-
1
-
-
84861978076
-
Host-gut microbiota metabolic interactions
-
Nicholson, J. K. et al. Host-gut microbiota metabolic interactions. Science 336, 1262-1267 (2012).
-
(2012)
Science
, vol.336
, pp. 1262-1267
-
-
Nicholson, J.K.1
-
2
-
-
0028039193
-
The metabolism of drugs by the gut flora
-
Mikov, M. The metabolism of drugs by the gut flora. Eur. J. Drug Metab. Pharmacokinet. 19, 201-207 (1994).
-
(1994)
Eur. J. Drug Metab. Pharmacokinet
, vol.19
, pp. 201-207
-
-
Mikov, M.1
-
3
-
-
0030888748
-
Aryl hydrocarbon receptor-mediated signal transduction
-
Rowlands, J. C. & Gustafsson, J.-A. Aryl hydrocarbon receptor-mediated signal transduction. Crit. Rev. Toxicol. 27, 109-134 (1997).
-
(1997)
Crit. Rev. Toxicol.
, vol.27
, pp. 109-134
-
-
Rowlands, J.C.1
Gustafsson, J.-A.2
-
4
-
-
0028987872
-
The aryl hydrocarbon receptor complex
-
Hankinson, O. The aryl hydrocarbon receptor complex. Annu. Rev. Pharmacol. Toxicol. 35, 307-340 (1995).
-
(1995)
Annu. Rev. Pharmacol. Toxicol
, vol.35
, pp. 307-340
-
-
Hankinson, O.1
-
5
-
-
0031895561
-
Rapid and transient induction of CYP1A1 gene expression in human cells by the tryptophan photoproduct 6-formylindolo(3, 2-b)carbazole
-
Wei, Y., Helleberg, H., Rannug, U. & Rannug, A. Rapid and transient induction of CYP1A1 gene expression in human cells by the tryptophan photoproduct 6-formylindolo(3, 2-b)carbazole. Chem. Biol. Interact. 110, 39-55 (1998).
-
(1998)
Chem. Biol., Interact
, vol.110
, pp. 39-55
-
-
Wei, Y.1
Helleberg, H.2
Rannug, U.3
Rannug, A.4
-
6
-
-
80054041992
-
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
-
Opitz, C. A. et al. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 478, 197-203 (2011).
-
(2011)
Nature
, vol.478
, pp. 197-203
-
-
Opitz, C.A.1
-
7
-
-
83855160821
-
Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles
-
Kiss, E. a. et al. Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles. Science 334, 1561-1565 (2011).
-
(2011)
Science
, vol.334
, pp. 1561-1565
-
-
Kiss, E.A.1
-
8
-
-
80155164160
-
Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation
-
Li, Y. et al. Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation. Cell 147, 629-640 (2011).
-
(2011)
Cell
, vol.147
, pp. 629-640
-
-
Li, Y.1
-
9
-
-
84901658581
-
Identification of a probiotic bacteria-derived activator of the aryl hydrocarbon receptor that inhibits colitis
-
Fukumoto, S. et al. Identification of a probiotic bacteria-derived activator of the aryl hydrocarbon receptor that inhibits colitis. Immunol. Cell Biol. 92, 460-465 (2014).
-
(2014)
Immunol. Cell Biol
, vol.92
, pp. 460-465
-
-
Fukumoto, S.1
-
10
-
-
84882664672
-
Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22
-
Zelante, T. et al. Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22. Immunity 39, 372-385 (2013).
-
(2013)
Immunity
, vol.39
, pp. 372-385
-
-
Zelante, T.1
-
11
-
-
80053906324
-
Lactobacillus bulgaricus OLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis
-
Takamura, T. et al. Lactobacillus bulgaricus OLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis. Immunol. Cell Biol. 89, 817-822 (2011).
-
(2011)
Immunol. Cell Biol
, vol.89
, pp. 817-822
-
-
Takamura, T.1
-
12
-
-
0017898940
-
Suppression of histone deacetylation in vivo and in vitro by sodium butyrate
-
Boffa, I. C., Vidali, G., Mann, R. S. & Allfrey, V. G. Suppression of histone deacetylation in vivo and in vitro by sodium butyrate. J. Biol. Chem. 253, 3364-3366 (1978).
-
(1978)
J. Biol. Chem
, vol.253
, pp. 3364-3366
-
-
Boffa, I.C.1
Vidali, G.2
Mann, R.S.3
Allfrey, V.G.4
-
13
-
-
0034105047
-
Butyrate and trichostatin A effects on the proliferation/differentiation of human intestinal epithelial cells: Induction of cyclin D3 and p21 expression
-
Siavoshian, S. et al. Butyrate and trichostatin A effects on the proliferation/differentiation of human intestinal epithelial cells: induction of cyclin D3 and p21 expression. Gut 46, 507-514 (2000).
-
(2000)
Gut
, vol.46
, pp. 507-514
-
-
Siavoshian, S.1
-
14
-
-
0017864644
-
The effect of sodium butyrate on histone modification
-
Sealy, L. & Chalkley, R. The effect of sodium butyrate on histone modification. Cell 14, 115-121 (1978).
-
(1978)
Cell
, vol.14
, pp. 115-121
-
-
Sealy, L.1
Chalkley, R.2
-
15
-
-
42149103211
-
Gut flora, Toll-like receptors and nuclear receptors: A tripartite communication that tunes innate immunity in large intestine
-
Lundin, A. et al. Gut flora, Toll-like receptors and nuclear receptors: A tripartite communication that tunes innate immunity in large intestine. Cell Microbiol. 10, 1093-1103 (2008).
-
(2008)
Cell Microbiol
, vol.10
, pp. 1093-1103
-
-
Lundin, A.1
-
16
-
-
57449087449
-
Regulation of gene expression of hepatic drug metabolizing enzymes and transporters by the Toll-like receptor 2 ligand, lipoteichoic acid
-
Ghose, R., Guo, T. & Haque, N. Regulation of gene expression of hepatic drug metabolizing enzymes and transporters by the Toll-like receptor 2 ligand, lipoteichoic acid. Arch. Biochem. Biophys. 481, 123-130 (2009).
-
(2009)
Arch. Biochem. Biophys
, vol.481
, pp. 123-130
-
-
Ghose, R.1
Guo, T.2
Haque, N.3
-
17
-
-
84858595413
-
TLR2 controls intestinal carcinogen detoxication by CYP1A1
-
Do, K. N., Fink, L. N., Jensen, T. E., Gautier, L. & Parlesak, A. TLR2 controls intestinal carcinogen detoxication by CYP1A1. PLoS ONE 7, e32309 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e32309
-
-
Do, K.N.1
Fink, L.N.2
Jensen, T.E.3
Gautier, L.4
Parlesak, A.5
-
18
-
-
84907382483
-
AhR sensing of bacterial pigments regulates antibacterial defence
-
Moura-Alves, P. et al. AhR sensing of bacterial pigments regulates antibacterial defence. Nature 512, 387-392 (2014).
-
(2014)
Nature
, vol.512
, pp. 387-392
-
-
Moura-Alves, P.1
-
19
-
-
84897374287
-
Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities
-
Jin, U.-H. et al. Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities. Mol. Pharmacol. 85, 777-788 (2014).
-
(2014)
Mol. Pharmacol
, vol.85
, pp. 777-788
-
-
Jin, U.-H.1
-
20
-
-
84863472497
-
A crypt-specific core microbiota resides in the mouse colon
-
Pédron, T. et al. A crypt-specific core microbiota resides in the mouse colon. MBio 3, e00116-e00212 (2012).
-
(2012)
MBio
, vol.3
, pp. e00116-e00212
-
-
Pédron, T.1
-
21
-
-
20544444045
-
Diversity of the human intestinal microbial flora
-
Eckburg, P. B. et al. Diversity of the human intestinal microbial flora. Science 308, 1635-1638 (2005).
-
(2005)
Science
, vol.308
, pp. 1635-1638
-
-
Eckburg, P.B.1
-
22
-
-
0034003005
-
Stress signals utilize multiple pathways to stabilize p53
-
Ashcroft, M., Taya, Y. & Vousden, K. H. Stress signals utilize multiple pathways to stabilize p53. Mol. Cell Biol. 20, 3224-3233 (2000).
-
(2000)
Mol. Cell, Biol.
, vol.20
, pp. 3224-3233
-
-
Ashcroft, M.1
Taya, Y.2
Vousden, K.H.3
-
23
-
-
74249089749
-
Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-Alpha3 binding
-
Marchenko, N. D. et al. Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-Alpha3 binding. Cell Death Differ. 17, 255-267 (2010).
-
(2010)
Cell Death Differ
, vol.17
, pp. 255-267
-
-
Marchenko, N.D.1
-
24
-
-
84891551481
-
Long-Term disruption of maternal glucose homeostasis induced by prenatal glucocorticoid treatment correlates with MIR-29 upregulation
-
Gomes, P. R. et al. Long-Term disruption of maternal glucose homeostasis induced by prenatal glucocorticoid treatment correlates with miR-29 upregulation. Am. J. Physiol. Endocrinol. Metab. 306, E109-E120 (2014).
-
(2014)
Am. J. Physiol. Endocrinol. Metab
, vol.306
, pp. E109-E120
-
-
Gomes, P.R.1
-
25
-
-
84924356420
-
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease
-
Youm, Y.-H. et al. The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. Nat. Med. 21, 263-269 (2015).
-
(2015)
Nat. Med
, vol.21
, pp. 263-269
-
-
Youm, Y.-H.1
-
26
-
-
35648933928
-
White adipose tissue: Storage and effector site for environmental pollutants
-
Müllerová, D. & Kopecký, J. White adipose tissue: storage and effector site for environmental pollutants. Physiol. Res. 56, 375-381 (2007).
-
(2007)
Physiol. Res
, vol.56
, pp. 375-381
-
-
Müllerová, D.1
Kopecký, J.2
-
27
-
-
67650848116
-
Endocrine disruptive chemicals: Mechanisms of action and involvement in metabolic disorders
-
Swedenborg, E., Rüegg, J., Mäkelä, S. & Pongratz, I. Endocrine disruptive chemicals: mechanisms of action and involvement in metabolic disorders. J. Mol. Endocrinol. 43, 1-10 (2009).
-
(2009)
J. Mol. Endocrinol
, vol.43
, pp. 1-10
-
-
Swedenborg, E.1
Rüegg, J.2
Mäkelä, S.3
Pongratz, I.4
-
28
-
-
84884560637
-
P53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production
-
Goldstein, I. et al. p53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production. Cancer Metab. 1, 9 (2013).
-
(2013)
Cancer Metab
, vol.1
, pp. 9
-
-
Goldstein, I.1
-
29
-
-
84880773540
-
QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: Diet-And sex-dependent, effects
-
Lin, C. et al. QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet-And sex-dependent effects. PLoS ONE 8, e68776 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e68776
-
-
Lin, C.1
-
30
-
-
33845874101
-
An obesity-Associated gut microbiome with increased capacity for energy harvest
-
Turnbaugh, P. J. et al. An obesity-Associated gut microbiome with increased capacity for energy harvest. Nature 444, 1027-1031 (2006).
-
(2006)
Nature
, vol.444
, pp. 1027-1031
-
-
Turnbaugh, P.J.1
-
31
-
-
41849127118
-
Marked alterations in the distal gut microbiome linked to diet-induced obesity
-
Turnbaugh, P. J., Backhed, F., Fulton, L. & Gordon, J. I. Marked alterations in the distal gut microbiome linked to diet-induced obesity. Cell Host Microbe 3, 213-223 (2008).
-
(2008)
Cell Host Microbe
, vol.3
, pp. 213-223
-
-
Turnbaugh, P.J.1
Backhed, F.2
Fulton, L.3
Gordon, J.I.4
-
32
-
-
58749112734
-
A core gut microbiome in obese and lean twins
-
Turnbaugh, P. J. et al. A core gut microbiome in obese and lean twins. Nature 457, 480-484 (2009).
-
(2009)
Nature
, vol.457
, pp. 480-484
-
-
Turnbaugh, P.J.1
-
33
-
-
77957262599
-
Absence of intestinal microbiota does not protect mice from diet-induced obesity
-
Fleissner, C. K. et al. Absence of intestinal microbiota does not protect mice from diet-induced obesity. Br J Nutr 104, 919-929 (2010).
-
(2010)
Br J Nutr
, vol.104
, pp. 919-929
-
-
Fleissner, C.K.1
-
34
-
-
78649887273
-
Composition and energy harvesting capacity of the gut microbiota: Relationship to diet, obesity and time in mouse models
-
Murphy, E. F. et al. Composition and energy harvesting capacity of the gut microbiota: Relationship to diet, obesity and time in mouse models. Gut 59, 1635-1642 (2010).
-
(2010)
Gut
, vol.59
, pp. 1635-1642
-
-
Murphy, E.F.1
-
35
-
-
84911884131
-
The gut microbiota influences blood-brain barrier permeability in mice
-
263ra158
-
Braniste, V. et al. The gut microbiota influences blood-brain barrier permeability in mice. Sci. Transl. Med. 6, 263ra158 (2014).
-
(2014)
Sci. Transl. Med
, vol.6
-
-
Braniste, V.1
-
36
-
-
0031241140
-
Loss of teratogenic response to 2, 3, 7, 8-Tetrachlorodibenzo-pdioxin (TCDD) in mice lacking the Ah (dioxin) receptor
-
Mimura, J. et al. Loss of teratogenic response to 2, 3, 7, 8-Tetrachlorodibenzo-pdioxin (TCDD) in mice lacking the Ah (dioxin) receptor. Genes Cells 2, 645-654 (1997).
-
(1997)
Genes Cells
, vol.2
, pp. 645-654
-
-
Mimura, J.1
-
37
-
-
84878662294
-
ANGPTL4 expression induced by butyrate and rosiglitazone in human intestinal epithelial cells utilizes independent pathways
-
Korecka, A. et al. ANGPTL4 expression induced by butyrate and rosiglitazone in human intestinal epithelial cells utilizes independent pathways. Am. J. Physiol. Gastrointest. Liver Physiol. 304, G1025-G1037 (2013).
-
(2013)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.304
, pp. G1025-G1037
-
-
Korecka, A.1
-
38
-
-
39149126712
-
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
-
Beckonert, O. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat. Protoc. 2, 2692-2703 (2007).
-
(2007)
Nat. Protoc
, vol.2
, pp. 2692-2703
-
-
Beckonert, O.1
-
39
-
-
84907886121
-
Precision high-Throughput proton NMR spectroscopy of human urine, serum, and plasma for large-scale metabolic phenotyping
-
Dona, A. C. et al. Precision high-Throughput proton NMR spectroscopy of human urine, serum, and plasma for large-scale metabolic phenotyping. Anal. Chem. 86, 9887-9894 (2014).
-
(2014)
Anal. Chem.
, vol.86
, pp. 9887-9894
-
-
Dona, A.C.1
-
40
-
-
33645663178
-
Scaling and normalization effects in NMR spectroscopic metabonomic data sets
-
Craig, A., Cloarec, O., Holmes, E., Nicholson, J. K. & Lindon, J. C. Scaling and normalization effects in NMR spectroscopic metabonomic data sets. Anal. Chem. 78, 2262-2267 (2006).
-
(2006)
Anal. Chem.
, vol.78
, pp. 2262-2267
-
-
Craig, A.1
Cloarec, O.2
Holmes, E.3
Nicholson, J.K.4
Lindon, J.C.5
-
41
-
-
0001413420
-
Metabolite profiling by one-And two-dimensional NMR analysis of complex mixtures
-
Fan, T. W.-M. Metabolite profiling by one-And two-dimensional NMR analysis of complex mixtures. Prog. Nucl. Magn. Reson. Spectrosc. 28, 161-219 (1996).
-
(1996)
Prog. Nucl. Magn. Reson. Spectrosc
, vol.28
, pp. 161-219
-
-
Fan, T.W.-M.1
-
42
-
-
0024946615
-
High resolution proton magnetic resonance spectroscopy of biological fluids
-
Nicholson, J. K. W. I. High resolution proton magnetic resonance spectroscopy of biological fluids. Prog. Nucl. Magn. Reson. Spectrosc. 21, 449-501 (1989).
-
(1989)
Prog. Nucl. Magn. Reson. Spectrosc.
, vol.21
, pp. 449-501
-
-
Nicholson, J.K.W.I.1
-
43
-
-
0029269288
-
750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma
-
Nicholson, J. K., Foxall, P. J., Spraul, M., Farrant, R. D. & Lindon, J. C. 750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma. Anal. Chem. 67, 793-811 (1995).
-
(1995)
Anal. Chem
, vol.67
, pp. 793-811
-
-
Nicholson, J.K.1
Foxall, P.J.2
Spraul, M.3
Farrant, R.D.4
Lindon, J.C.5
-
44
-
-
20144388102
-
Comparative metabonomics of differential hydrazine toxicity in the rat and mouse
-
Bollard, M. E. et al. Comparative metabonomics of differential hydrazine toxicity in the rat and mouse. Toxicol. Appl. Pharmacol. 204, 135-151 (2005).
-
(2005)
Toxicol. Appl. Pharmacol
, vol.204
, pp. 135-151
-
-
Bollard, M.E.1
-
45
-
-
0035796127
-
Pattern recognition methods and applications in biomedical magnetic resonance
-
Lindon, J. C., Holmes, E. & Nicholson, J. K. Pattern recognition methods and applications in biomedical magnetic resonance. Prog. Nucl. Magn. Reson. Spectrosc. 39, 1-40 (2001).
-
(2001)
Prog. Nucl. Magn. Reson. Spectrosc
, vol.39
, pp. 1-40
-
-
Lindon, J.C.1
Holmes, E.2
Nicholson, J.K.3
-
46
-
-
33750979266
-
PCR DGGE and RT-PCR DGGE show diversity and short-Term temporal stability in the Clostridium coccoides-Eubacterium rectale group in the human intestinal microbiota
-
Maukonen, J. et al. PCR DGGE and RT-PCR DGGE show diversity and short-Term temporal stability in the Clostridium coccoides-Eubacterium rectale group in the human intestinal microbiota. FEMS Microbiol. Ecol. 58, 517-528 (2006).
-
(2006)
FEMS Microbiol., Ecol.
, vol.58
, pp. 517-528
-
-
Maukonen, J.1
-
47
-
-
84872798237
-
Comparison of the distal gut microbiota from people and animals in Africa
-
Ellis, R. J. et al. Comparison of the distal gut microbiota from people and animals in Africa. PLoS ONE 8, e54783 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e54783
-
-
Ellis, R.J.1
-
48
-
-
77952243141
-
QIIME allows analysis of high-Throughput community sequencing data
-
Caporaso, J. G. et al. QIIME allows analysis of high-Throughput community sequencing data. Nat. Methods 7, 335-336 (2010).
-
(2010)
Nat. Methods
, vol.7
, pp. 335-336
-
-
Caporaso, J.G.1
-
49
-
-
77957244650
-
Search and clustering orders of magnitude faster than BLAST
-
Edgar, R. C. Search and clustering orders of magnitude faster than BLAST. Bioinformatics 26, 2460-2461 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 2460-2461
-
-
Edgar, R.C.1
-
50
-
-
34548293679
-
Naïve Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy
-
Wang, Q., Garrity, G. M., Tiedje, J. M. & Cole, J. R. Naïve Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy. Appl. Environ. Microbiol. 73, 5261-5267 (2007).
-
(2007)
Appl. Environ. Microbiol
, vol.73
, pp. 5261-5267
-
-
Wang, Q.1
Garrity, G.M.2
Tiedje, J.M.3
Cole, J.R.4
-
51
-
-
33746061683
-
Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB
-
De Santis, T. Z. et al. Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB. Appl. Environ. Microbiol. 72, 5069-5072 (2006).
-
(2006)
Appl. Environ. Microbiol
, vol.72
, pp. 5069-5072
-
-
De Santis, T.Z.1
|