Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-α3 binding

Cell Death and Differentiation

Volumn 17, Issue 2, 2010, Pages 255-267

  Marchenko, N D ^a   Hanel, W ^a   Li, D ^a   Becker, K ^a   Reich, N ^a   Moll, U M ^a,b  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Importin ; MDM2; Nuclear import; P53; Ubiquitination

Indexed keywords

AMINO ACID; IMPORTIN ALPHA3; KARYOPHERIN; LYSINE; PROTEIN MDM2; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL FRACTIONATION; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; NUCLEAR LOCALIZATION SIGNAL; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; REGULATORY MECHANISM; RNA INTERFERENCE; STRESS; UBIQUITINATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ADENOCARCINOMA; ALPHA KARYOPHERINS; CELL DIVISION; CELL NUCLEUS; COLONIC NEOPLASMS; CYTOPLASM; HCT116 CELLS; HUMANS; LUNG NEOPLASMS; LYSINE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-MDM2; STRESS, PHYSIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINATION;

EID: 74249089749     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.173     Document Type: Article

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