Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 115, Issue 6, 2018, Pages E1147-E1156

  Djurec, Magdolna ^a   Graña, Osvaldo ^a   Lee, Albert ^b   Troulé, Kevin ^a   Espinet, Elisa ^c,d   Cabras, Lavinia ^a   Navas, Carolina ^a   Blasco, María Teresa ^a   Martín Díaz, Laura ^a   Burdiel, Miranda ^a   Li, Jing ^a   Liu, Zhaoqi ^b   Vallespinós, Mireia ^e,f   Sanchez Bueno, Francisco ^g   Sprick, Martin R ^d   Trumpp, Andreas ^c,d   Sainz, Bruno ^e,f   Al Shahrour, Fátima ^a   Rabadan, Raul ^b   Guerra, Carmen ^a   Barbacid, Mariano ^a   more..

^a Structural Biology and Biocomputing Programme   (Spain)

^b Department of Medicine   (United States)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI STEM)   (Germany)

^e AUTONOMOUS UNIVERSITY OF MADRID   (Spain)

^f INSTITUTO RAMÓN Y CAJAL DE INVESTIGACIÓN SANITARIA IRYCIS   (Spain)

^g HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

Author keywords

CAFs; Mouse models; PDAC; Saa3; Stroma

Indexed keywords

MEMBRANE PROTEIN; MPP6 PROTEIN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; SERUM AMYLOID A; UNCLASSIFIED DRUG; SAA1 PROTEIN, HUMAN; SAA3 PROTEIN, MOUSE; SAA3P PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER ASSOCIATED FIBROBLAST; CANCER PROGNOSIS; CANCER SURVIVAL; CARCINOGENICITY; CELL INTERACTION; CONTROLLED STUDY; FEMALE; GENE; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; SAA1 GENE; SAA3 GENE; TUMOR CELL; TUMOR GROWTH; ANIMAL; C57BL MOUSE; CELL MOTION; CELL PROLIFERATION; GENETICS; HIGH THROUGHPUT SEQUENCING; KNOCKOUT MOUSE; METABOLISM; PANCREAS; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; PHYSIOLOGY; STROMA CELL; TUMOR MICROENVIRONMENT;

ANIMALS; CANCER-ASSOCIATED FIBROBLASTS; CARCINOMA, PANCREATIC DUCTAL; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PANCREAS; PANCREATIC NEOPLASMS; SERUM AMYLOID A PROTEIN; STROMAL CELLS; TUMOR MICROENVIRONMENT;

EID: 85041554314     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1717802115     Document Type: Article

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