A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion

Nature Cell Biology

Volumn 19, Issue 3, 2017, Pages 224-237

  Labernadie, Anna ^a   Kato, Takuya ^b   Brugués, Agustí ^a   Serra Picamal, Xavier ^a,c   Derzsi, Stefanie ^b   Arwert, Esther ^b   Weston, Anne ^b   González Tarragó, Victor ^a   Elosegui Artola, Alberto ^a   Albertazzi, Lorenzo ^a   Alcaraz, Jordi ^c   Roca Cusachs, Pere ^a,c   Sahai, Erik ^b   Trepat, Xavier ^a,c,d,e  

^a INSTITUTE FOR BIOENGINEERING OF CATALONIA IBEC   (Spain)

^b THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^c UNIVERSITY OF BARCELONA   (Spain)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^e BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AFADIN; ALPHA CATENIN; BETA CATENIN; BINDING PROTEIN; CELL ADHESION MOLECULE; NECTIN; NERVE CELL ADHESION MOLECULE; UNCLASSIFIED DRUG; UVOMORULIN; VINCULIN; ACTIN BINDING PROTEIN; CADHERIN; NECTINS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER ASSOCIATED FIBROBLAST; CANCER CELL; CELL ADHESION; CELL MEMBRANE; CELL MIGRATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPOLARIZATION; TUMOR INVASION; ADENOCARCINOMA; BIOMECHANICS; CELL MIGRATION ASSAY; CELL MOTION; CELL POLARITY; COCULTURE; LUNG TUMOR; MECHANOTRANSDUCTION; METABOLISM; MULTICELLULAR SPHEROID; NEOPLASM; OPTICAL TWEEZERS; PATHOLOGY; SQUAMOUS CELL CARCINOMA; THREE DIMENSIONAL IMAGING; TUMOR CELL LINE; ULTRASTRUCTURE; VULVA TUMOR;

ADENOCARCINOMA; BIOMECHANICAL PHENOMENA; CADHERINS; CANCER-ASSOCIATED FIBROBLASTS; CELL ADHESION; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL MIGRATION ASSAYS; CELL MOVEMENT; CELL POLARITY; COCULTURE TECHNIQUES; FEMALE; HUMANS; IMAGING, THREE-DIMENSIONAL; LUNG NEOPLASMS; MECHANOTRANSDUCTION, CELLULAR; MICROFILAMENT PROTEINS; NEOPLASM INVASIVENESS; NEOPLASMS; NEOPLASMS, SQUAMOUS CELL; OPTICAL TWEEZERS; SPHEROIDS, CELLULAR; VULVAR NEOPLASMS;

EID: 85014184482     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3478     Document Type: Article

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