메뉴 건너뛰기




Volumn 17, Issue 3, 2018, Pages 293-302

A comparative safety review between GLP-1 receptor agonists and SGLT2 inhibitors for diabetes treatment

Author keywords

cardiovascular; GLP 1 receptor agonists; outcome studies; safety; SGLT2 inhibitors

Indexed keywords

CANAGLIFLOZIN; DAPAGLIFLOZIN; DULAGLUTIDE; EMPAGLIFLOZIN; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; LIRAGLUTIDE; LIXISENATIDE; SEMAGLUTIDE; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; ANTIDIABETIC AGENT; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLYCOSYLATED HEMOGLOBIN; SLC5A2 PROTEIN, HUMAN; SODIUM GLUCOSE COTRANSPORTER 2;

EID: 85041501364     PISSN: 14740338     EISSN: 1744764X     Source Type: Journal    
DOI: 10.1080/14740338.2018.1428305     Document Type: Review
Times cited : (33)

References (106)
  • 1
    • 84995662272 scopus 로고    scopus 로고
    • Practical combination therapy based on pathophysiology of type 2 diabetes
    • Levin PA., Practical combination therapy based on pathophysiology of type 2 diabetes. Diabetes Metab Syndr Obes Targets Ther. 2016;9:355–369.
    • (2016) Diabetes Metab Syndr Obes Targets Ther , vol.9 , pp. 355-369
    • Levin, P.A.1
  • 2
    • 85021428641 scopus 로고    scopus 로고
    • Combination SGLT2 inhibitor and GLP-1 receptor agonist therapy: a complementary approach to the treatment of type 2 diabetes
    • Busch RS, Kane MP., Combination SGLT2 inhibitor and GLP-1 receptor agonist therapy: a complementary approach to the treatment of type 2 diabetes. Postgrad Med [Internet]. 2017;1–12. Available from https://www.tandfonline.com/doi/full/10.1080/00325481.2017.1342509%0Ahttp://www.ncbi.nlm.nih.gov/pubmed/28657399
    • (2017) Postgrad Med [Internet] , pp. 1-12
    • Busch, R.S.1    Kane, M.P.2
  • 3
    • 84979609753 scopus 로고    scopus 로고
    • Positioning SGLT2 Inhibitors/Incretin-Based Therapies in the Treatment Algorithm
    • Wilding JPH, Rajeev SP, DeFronzo RA. Positioning SGLT2 Inhibitors/Incretin-Based Therapies in the Treatment Algorithm. Diabetes Care [Internet]. 2016;39:S154–S164. Available from http://care.diabetesjournals.org/lookup/doi/10.2337/dcS15-3005
    • (2016) Diabetes Care [Internet] , vol.39 , pp. S154-S164
    • Wilding, J.P.H.1    Rajeev, S.P.2    DeFronzo, R.A.3
  • 4
    • 84864270406 scopus 로고    scopus 로고
    • Basal insulin and cardiovascular and other outcomes in dysglycemia
    • et al
    • Gerstein HC, Bosch J, Dagenais GR, et al. Basal insulin and cardiovascular and other outcomes in dysglycemia. N Engl J Med. 2012;367:319–328.
    • (2012) N Engl J Med , vol.367 , pp. 319-328
    • Gerstein, H.C.1    Bosch, J.2    Dagenais, G.R.3
  • 5
    • 54949085654 scopus 로고    scopus 로고
    • Effects of intensive glucose lowering in type 2 diabetes the action to control cardiovascular risk in diabetes study group*
    • et al,;358
    • Sciences HH, Miller ME, Byington RP, et al. Effects of intensive glucose lowering in type 2 diabetes the action to control cardiovascular risk in diabetes study group*. N Engl J Med. 2008;358:2545–2559.
    • (2008) N Engl J Med , pp. 2545-2559
    • Sciences, H.H.1    Miller, M.E.2    Byington, R.P.3
  • 6
    • 84923791994 scopus 로고    scopus 로고
    • Pharmacodynamics, efficacy and safety of sodium–glucose co-transporter type 2 (SGLT2) inhibitors for the treatment of type 2 diabetes mellitus
    • cited 2017 Oct26
    • Scheen AJ. Pharmacodynamics, efficacy and safety of sodium–glucose co-transporter type 2 (SGLT2) inhibitors for the treatment of type 2 diabetes mellitus. Drugs [Internet]. 2015;75:33–59. [cited 2017 Oct26]. Available from http://link.springer.com/10.1007/s40265-014-0337-y
    • (2015) Drugs [Internet] , vol.75 , pp. 33-59
    • Scheen, A.J.1
  • 7
    • 84957665720 scopus 로고    scopus 로고
    • The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions
    • cited 2017 Nov2
    • Nauck MA, Meier JJ. The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions. Lancet Diabetes Endocrinol [Internet]. 2016;4:525–536. [cited 2017 Nov2]. Available from http://www.sciencedirect.com/science/article/pii/S2213858715004829?via%3Dihub
    • (2016) Lancet Diabetes Endocrinol [Internet] , vol.4 , pp. 525-536
    • Nauck, M.A.1    Meier, J.J.2
  • 8
    • 85020473445 scopus 로고    scopus 로고
    • Combination therapy with GLP-1 receptor agonist and SGLT2 inhibitor
    • cited 2017 Nov2
    • DeFronzo RA. Combination therapy with GLP-1 receptor agonist and SGLT2 inhibitor. Diabetes Obes Metab [Internet]. 2017;19:1353–1362. [cited 2017 Nov2]. Available from http://www.ncbi.nlm.nih.gov/pubmed/28432726
    • (2017) Diabetes Obes Metab [Internet] , vol.19 , pp. 1353-1362
    • DeFronzo, R.A.1
  • 9
    • 84929377076 scopus 로고    scopus 로고
    • Dapagliflozin lowers plasma glucose concentration and improves β-cell function
    • cited 2017 Nov2
    • Merovci A, Mari A, Solis C, et al. Dapagliflozin lowers plasma glucose concentration and improves β-cell function. J Clin Endocrinol Metab [Internet]. 2015 [cited 2017 Nov2];100:1927–1932. Available from http://www.ncbi.nlm.nih.gov/pubmed/25710563
    • (2015) J Clin Endocrinol Metab [Internet] , vol.100 , pp. 1927-1932
    • Merovci, A.1    Mari, A.2    Solis, C.3
  • 10
    • 85040168055 scopus 로고    scopus 로고
    • Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes
    • NEJMoa1612917
    • Holman RR, Bethel MA, Mentz RJ, et al. Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes. N Engl J Med [Internet] NEJMoa1612917. 2017. Available from: http://www.nejm.org/doi/10.1056/NEJMoa1612917
    • (2017) N Engl J Med [Internet]
    • Holman, R.R.1    Bethel, M.A.2    Mentz, R.J.3
  • 11
    • 84962338740 scopus 로고    scopus 로고
    • Efficacy and safety of once-weekly dulaglutide versus insulin glargine in patients with type 2 diabetes on metformin and glimepiride (AWARD-2)
    • et al
    • Giorgino F, Benroubi M, Sun J-H, et al. Efficacy and safety of once-weekly dulaglutide versus insulin glargine in patients with type 2 diabetes on metformin and glimepiride (AWARD-2). Diabetes Care. 2015;38:2241–2249.
    • (2015) Diabetes Care , vol.38 , pp. 2241-2249
    • Giorgino, F.1    Benroubi, M.2    Sun, J.-H.3
  • 12
    • 84978839381 scopus 로고    scopus 로고
    • Brown-Frandsen K, et al. Liraglutide and Cardiovascular Outcomesin Type 2 Diabetes. N Engl J Med., Jul 28
    • Marso SP, Daniels GH, Brown-Frandsen K, et al. Liraglutide and Cardiovascular Outcomesin Type 2 Diabetes. N Engl J Med. 2016 Jul 28;375(4):311–322
    • (2016) , vol.375 , Issue.4 , pp. 311-322
    • Marso, S.P.1    Daniels, G.H.2
  • 13
    • 84948740668 scopus 로고    scopus 로고
    • Lixisenatide in patients with type 2 diabetes and acute coronary syndrome
    • et al
    • Pfeffer MA, Claggett B, Diaz R, et al. Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. N Engl J Med. 2015;373:2247–2257.
    • (2015) N Engl J Med , vol.373 , pp. 2247-2257
    • Pfeffer, M.A.1    Claggett, B.2    Diaz, R.3
  • 14
    • 84944800184 scopus 로고    scopus 로고
    • Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
    • cited 2017 Nov2
    • Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med [Internet]. 2015;373:2117–2128. [cited 2017 Nov2]. Available from: http://www.nejm.org/doi/10.1056/NEJMoa1504720
    • (2015) N Engl J Med [Internet] , vol.373 , pp. 2117-2128
    • Zinman, B.1    Wanner, C.2    Lachin, J.M.3
  • 15
    • 84945175811 scopus 로고    scopus 로고
    • Dapagliflozin’s effects on glycemia and cardiovascular risk factors in high-risk patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled study with a 28-week extension
    • et al
    • Cefalu WT, Leiter LA, De Bruin TWA, et al. Dapagliflozin’s effects on glycemia and cardiovascular risk factors in high-risk patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled study with a 28-week extension. Diabetes Care. 2015;38:1218–1227.
    • (2015) Diabetes Care , vol.38 , pp. 1218-1227
    • Cefalu, W.T.1    Leiter, L.A.2    De Bruin, T.W.A.3
  • 16
    • 85023777061 scopus 로고    scopus 로고
    • Canagliflozin and cardiovascular and renal events in type 2 diabetes
    • et al
    • Neal B, Perkovic V, Mahaffey KW, et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med. 2017;377:644–657.
    • (2017) N Engl J Med , vol.377 , pp. 644-657
    • Neal, B.1    Perkovic, V.2    Mahaffey, K.W.3
  • 19
    • 0037387745 scopus 로고    scopus 로고
    • Diagnosis and treatment of diabetic ketoacidosis and the hyperglycemic hyperosmolar state
    • cited 2017 Nov7
    • Chiasson J-L, Aris-Jilwan N, Bélanger R, et al. Diagnosis and treatment of diabetic ketoacidosis and the hyperglycemic hyperosmolar state. CMAJ [Internet]. 2003 [cited 2017 Nov7];168:859–866. Available from http://www.ncbi.nlm.nih.gov/pubmed/12668546
    • (2003) CMAJ [Internet] , vol.168 , pp. 859-866
    • Chiasson, J.-L.1    Aris-Jilwan, N.2    Bélanger, R.3
  • 20
    • 84959366596 scopus 로고    scopus 로고
    • Euglycemic diabetic ketoacidosis induced by SGLT2 inhibitors: possible mechanism and contributing factors
    • cited 2017 Nov7
    • Ogawa W, Sakaguchi K. Euglycemic diabetic ketoacidosis induced by SGLT2 inhibitors: possible mechanism and contributing factors. J Diabetes Investig [Internet]. 2016;7:135–138. [cited 2017 Nov7]. Available from http://doi.wiley.com/10.1111/jdi.12401
    • (2016) J Diabetes Investig [Internet] , vol.7 , pp. 135-138
    • Ogawa, W.1    Sakaguchi, K.2
  • 22
    • 85006820094 scopus 로고    scopus 로고
    • SGLT2 inhibitor–associated diabetic ketoacidosis: clinical review and recommendations for prevention and diagnosis
    • cited 2017 Nov6
    • Goldenberg RM, Berard LD, Cheng AYY, et al. SGLT2 inhibitor–associated diabetic ketoacidosis: clinical review and recommendations for prevention and diagnosis. Clin Ther [Internet]. 2016;38:2654–2664.e1. [cited 2017 Nov6]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28003053
    • (2016) Clin Ther [Internet] , vol.38 , pp. 2654-2664
    • Goldenberg, R.M.1    Berard, L.D.2    Cheng, A.Y.Y.3
  • 23
    • 77950111202 scopus 로고    scopus 로고
    • Elevated resting heart rate is an independent risk factor for cardiovascular disease in healthy men and women
    • cited 2017 Nov6
    • Cooney MT, Vartiainen E, Laakitainen T, et al. Elevated resting heart rate is an independent risk factor for cardiovascular disease in healthy men and women. Am Heart J [Internet]. 2010. [cited 2017 Nov6];159:612–619.e3. Available from http://www.ncbi.nlm.nih.gov/pubmed/20362720
    • (2010) Am Heart J [Internet] , vol.159 , pp. 612-619
    • Cooney, M.T.1    Vartiainen, E.2    Laakitainen, T.3
  • 24
    • 84946543383 scopus 로고    scopus 로고
    • Association between resting heart rate and cardiovascular mortality: evidence from a meta-analysis of prospective studies
    • cited 2017 Nov6
    • Li Y. Association between resting heart rate and cardiovascular mortality: evidence from a meta-analysis of prospective studies. Int J Clin Exp Med [Internet]. 2015;8:15329–15339. [cited 2017 Nov6]. Available from http://www.ncbi.nlm.nih.gov/pubmed/26629022
    • (2015) Int J Clin Exp Med [Internet] , vol.8 , pp. 15329-15339
    • Li, Y.1
  • 25
    • 84873554686 scopus 로고    scopus 로고
    • Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis
    • cited 2017 Nov6
    • Robinson LE, Holt TA, Rees K, et al. Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis. BMJ Open [Internet]. 2013;3:e001986. [cited 2017 Nov6]. Available from http://www.ncbi.nlm.nih.gov/pubmed/23355666
    • (2013) BMJ Open [Internet] , vol.3 , pp. e001986
    • Robinson, L.E.1    Holt, T.A.2    Rees, K.3
  • 26
    • 84862785543 scopus 로고    scopus 로고
    • Resting heart rate and the risk of death and cardiovascular complications in patients with type 2 diabetes mellitus
    • cited 2017 Dec1
    • Hillis GS, Woodward M, Rodgers A, et al. Resting heart rate and the risk of death and cardiovascular complications in patients with type 2 diabetes mellitus. Diabetologia [Internet]. 2012. [cited 2017 Dec1];55:1283–1290. Available from http://www.ncbi.nlm.nih.gov/pubmed/22286552
    • (2012) Diabetologia [Internet] , vol.55 , pp. 1283-1290
    • Hillis, G.S.1    Woodward, M.2    Rodgers, A.3
  • 27
    • 84948740668 scopus 로고    scopus 로고
    • Lixisenatide in patients with type 2 diabetes and acute coronary syndrome
    • cited 2017 Oct26
    • Pfeffer MA, Claggett B, Diaz R, et al. Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. N Engl J Med [Internet]. 2015. [cited 2017 Oct26];373:2247–2257. Available from http://www.ncbi.nlm.nih.gov/pubmed/26630143
    • (2015) N Engl J Med [Internet] , vol.373 , pp. 2247-2257
    • Pfeffer, M.A.1    Claggett, B.2    Diaz, R.3
  • 28
    • 85041530512 scopus 로고    scopus 로고
    • Cardiovascular benefits and safety of non-insulin medications used in the treatment of type 2 diabetes mellitus
    • Wroge J, Williams NT, Li L, et al. Cardiovascular benefits and safety of non-insulin medications used in the treatment of type 2 diabetes mellitus. Postgrad Med [Internet]. 2017;1–11. Available from http://m.jasn.asnjournals.org/content/early/2017/06/01/ASN.2016121372.abstract?papetoc%5Cnhttp://www.jasn.org/lookup/doi/10.1681/ASN.2016121372%5Cnwww.jasn.org
    • (2017) Postgrad Med [Internet] , pp. 1-11
    • Wroge, J.1    Williams, N.T.2    Li, L.3
  • 29
    • 84955439795 scopus 로고    scopus 로고
    • GLP-1 agonists and blood pressure: a review of the evidence
    • cited 2017 6
    • Goud A, Zhong J, Peters M, et al. GLP-1 agonists and blood pressure: a review of the evidence. Curr Hypertens Rep [Internet]. 2016 [cited 2017 6];18:16. Available from http://link.springer.com/10.1007/s11906-015-0621-6
    • (2016) Curr Hypertens Rep [Internet] , vol.18 , pp. 16
    • Goud, A.1    Zhong, J.2    Peters, M.3
  • 30
    • 84890536384 scopus 로고    scopus 로고
    • Effect of GLP-1 mimetics on blood pressure and relationship to weight loss and glycemia lowering: results of a systematic meta-analysis and meta-regression
    • cited 2017 Nov6
    • Katout M, Zhu H, Rutsky J, et al. Effect of GLP-1 mimetics on blood pressure and relationship to weight loss and glycemia lowering: results of a systematic meta-analysis and meta-regression. Am J Hypertens [Internet]. 2014 [cited 2017 Nov6];27:130–139. Available from http://www.ncbi.nlm.nih.gov/pubmed/24263424
    • (2014) Am J Hypertens [Internet] , vol.27 , pp. 130-139
    • Katout, M.1    Zhu, H.2    Rutsky, J.3
  • 31
    • 84901198078 scopus 로고    scopus 로고
    • Blood pressure effects of sodium–glucose co-transport 2 (SGLT2) inhibitors
    • cited 2017 Nov6
    • Oliva RV, Bakris GL. Blood pressure effects of sodium–glucose co-transport 2 (SGLT2) inhibitors. J Am Soc Hypertens [Internet]. 2014;8:330–339. [cited 2017 Nov6]. Available from http://www.ncbi.nlm.nih.gov/pubmed/24631482
    • (2014) J Am Soc Hypertens [Internet] , vol.8 , pp. 330-339
    • Oliva, R.V.1    Bakris, G.L.2
  • 32
    • 84923448295 scopus 로고    scopus 로고
    • SGLT-2 inhibitors and cardiovascular risk: proposed pathways and review of ongoing outcome trials
    • cited 2017 Nov6
    • Inzucchi SE, Zinman B, Wanner C, et al. SGLT-2 inhibitors and cardiovascular risk: proposed pathways and review of ongoing outcome trials. Diabetes Vasc Dis Res [Internet]. 2015 [cited 2017 Nov6];12:90–100. Available from http://www.ncbi.nlm.nih.gov/pubmed/25589482
    • (2015) Diabetes Vasc Dis Res [Internet] , vol.12 , pp. 90-100
    • Inzucchi, S.E.1    Zinman, B.2    Wanner, C.3
  • 33
    • 84898854471 scopus 로고    scopus 로고
    • Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: A systematic review and meta-analysis
    • cited 2017 Nov6
    • Baker WL, Smyth LR, Riche DM, et al. Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: A systematic review and meta-analysis. J Am Soc Hypertens [Internet]. 2014 [cited 2017 Nov6];8:262–275.e9. Available from http://www.ncbi.nlm.nih.gov/pubmed/24602971
    • (2014) J Am Soc Hypertens [Internet] , vol.8 , pp. 262-275
    • Baker, W.L.1    Smyth, L.R.2    Riche, D.M.3
  • 34
    • 1442299811 scopus 로고    scopus 로고
    • Heart failure prevalence, incidence, and mortality in the elderly with diabetes
    • cited 2017 Nov2
    • Bertoni AG, Hundley WG, Massing MW, et al. Heart failure prevalence, incidence, and mortality in the elderly with diabetes. Diabetes Care [Internet]. 2004 [cited 2017 Nov2];27:699–703. Available from http://www.ncbi.nlm.nih.gov/pubmed/14988288
    • (2004) Diabetes Care [Internet] , vol.27 , pp. 699-703
    • Bertoni, A.G.1    Hundley, W.G.2    Massing, M.W.3
  • 35
    • 84883765959 scopus 로고    scopus 로고
    • Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus
    • cited 2017 Nov15
    • Scirica BM, Bhatt DL, Braunwald E, et al. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med [Internet]. 2013 [cited 2017 Nov15];369:1317–1326. Available from http://www.ncbi.nlm.nih.gov/pubmed/23992601
    • (2013) N Engl J Med [Internet] , vol.369 , pp. 1317-1326
    • Scirica, B.M.1    Bhatt, D.L.2    Braunwald, E.3
  • 36
    • 84883745765 scopus 로고    scopus 로고
    • Alogliptin after acute coronary syndrome in patients with type 2 diabetes
    • et al
    • White WB, Cannon CP, Heller SR, et al. Alogliptin after acute coronary syndrome in patients with type 2 diabetes. N Engl J Med. 2013;369:1327–1335.
    • (2013) N Engl J Med , vol.369 , pp. 1327-1335
    • White, W.B.1    Cannon, C.P.2    Heller, S.R.3
  • 37
    • 85017233857 scopus 로고    scopus 로고
    • GLP-1 receptor agonists and heart failure in diabetes
    • Scheen AJ. GLP-1 receptor agonists and heart failure in diabetes. Diabetes Metab [Internet]. 2017;43:2S13–2S19. Available from https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017233857&doi=10.1016%2FS1262-3636%2817%2930068-X&partnerID=40&md5=f35f150e492c41b7615b65aadf5be99b
    • (2017) Diabetes Metab [Internet] , vol.43 , pp. 2S13-2S19
    • Scheen, A.J.1
  • 38
    • 85019731757 scopus 로고    scopus 로고
    • Lower risk of heart failure and death in patients initiated on sodium-glucose cotransporter-2 inhibitors versus other glucose-lowering drugsclinical perspective
    • cited 2017 Nov2
    • Kosiborod M, Cavender MA, Fu AZ, et al. Lower risk of heart failure and death in patients initiated on sodium-glucose cotransporter-2 inhibitors versus other glucose-lowering drugsclinical perspective. Circulation [Internet]. 2017 [cited 2017 Nov2];136:249–259. Available from http://www.ncbi.nlm.nih.gov/pubmed/28522450
    • (2017) Circulation [Internet] , vol.136 , pp. 249-259
    • Kosiborod, M.1    Cavender, M.A.2    Fu, A.Z.3
  • 39
    • 85034774651 scopus 로고    scopus 로고
    • Canagliflozin and cardiovascular and renal events in type 2 diabetes
    • cited 2017 Nov2
    • Neal B, Perkovic V, Mahaffey KW, et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med [Internet]. 2017 [cited 2017 Nov2];377:644–657. Available from http://www.nejm.org/doi/10.1056/NEJMoa1611925
    • (2017) N Engl J Med [Internet] , vol.377 , pp. 644-657
    • Neal, B.1    Perkovic, V.2    Mahaffey, K.W.3
  • 40
    • 85007452917 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonists and heart failure in type 2 diabetes: systematic review and meta-analysis of randomized and observational studies
    • cited 2017 Nov2
    • Li L, Li S, Liu J, et al. Glucagon-like peptide-1 receptor agonists and heart failure in type 2 diabetes: systematic review and meta-analysis of randomized and observational studies. BMC Cardiovasc Disord [Internet]. 2016 [cited 2017 Nov2];16:91. Available from http://www.ncbi.nlm.nih.gov/pubmed/27169565
    • (2016) BMC Cardiovasc Disord [Internet] , vol.16 , pp. 91
    • Li, L.1    Li, S.2    Liu, J.3
  • 41
    • 84948740668 scopus 로고    scopus 로고
    • Lixisenatide in patients with type 2 diabetes and acute coronary syndrome
    • cited 2017 Nov2
    • Pfeffer MA, Claggett B, Diaz R, et al. Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. N Engl J Med [Internet]. 2015 [cited 2017 Nov2];373:2247–2257. Available from http://www.nejm.org/doi/10.1056/NEJMoa1509225
    • (2015) N Engl J Med [Internet] , vol.373 , pp. 2247-2257
    • Pfeffer, M.A.1    Claggett, B.2    Diaz, R.3
  • 42
    • 84978839381 scopus 로고    scopus 로고
    • Liraglutide and cardiovascular outcomes in type 2 diabetes
    • cited 2017 Nov2
    • Marso SP, Daniels GH, Brown-Frandsen K, et al. Liraglutide and cardiovascular outcomes in type 2 diabetes. N Engl J Med [Internet]. 2016;375:311–322. [cited 2017 Nov2]. Available from: http://www.nejm.org/doi/10.1056/NEJMoa1603827
    • (2016) N Engl J Med [Internet] , vol.375 , pp. 311-322
    • Marso, S.P.1    Daniels, G.H.2    Brown-Frandsen, K.3
  • 43
    • 85030448557 scopus 로고    scopus 로고
    • Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes
    • cited 2017 Nov2
    • Holman RR, Bethel MA, Mentz RJ, et al. Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes. N Engl J Med [Internet]. 2017 [cited 2017 Nov2];377:1228–1239. Available from http://www.ncbi.nlm.nih.gov/pubmed/28910237
    • (2017) N Engl J Med [Internet] , vol.377 , pp. 1228-1239
    • Holman, R.R.1    Bethel, M.A.2    Mentz, R.J.3
  • 44
    • 84982082404 scopus 로고    scopus 로고
    • Effects of liraglutide on clinical stability among patients with advanced heart failure and reduced ejection fraction
    • cited 2017 Nov16
    • Margulies KB, Hernandez AF, Redfield MM, et al. Effects of liraglutide on clinical stability among patients with advanced heart failure and reduced ejection fraction. JAMA [Internet]. 2016 [cited 2017 Nov16];316:500. Available from http://www.ncbi.nlm.nih.gov/pubmed/27483064
    • (2016) JAMA [Internet] , vol.316 , pp. 500
    • Margulies, K.B.1    Hernandez, A.F.2    Redfield, M.M.3
  • 45
    • 84897408865 scopus 로고    scopus 로고
    • The perils of clinical trials
    • cited 2017 Nov2
    • Gilbert RE. The perils of clinical trials. Kidney Int [Internet]. 2014;85:745–747. [cited 2017 Nov2]. Available from http://www.sciencedirect.com/science/article/pii/S0085253815562832
    • (2014) Kidney Int [Internet] , vol.85 , pp. 745-747
    • Gilbert, R.E.1
  • 46
    • 85023746021 scopus 로고    scopus 로고
    • Cardiovascular safety of antidiabetic drugs in the hospital setting
    • Seggelke SA, Lindsay MC, Hazlett I, et al. Cardiovascular safety of antidiabetic drugs in the hospital setting. Curr Diab Rep [Internet]. 2017;64:17. Available from http://link.springer.com/10.1007/s11892-017-0884-1
    • (2017) Curr Diab Rep [Internet] , vol.64 , pp. 17
    • Seggelke, S.A.1    Lindsay, M.C.2    Hazlett, I.3
  • 47
    • 84994813253 scopus 로고    scopus 로고
    • Semaglutide and cardiovascular outcomes in patients with type 2 diabetes
    • et al
    • Marso SP, Bain SC, Consoli A, et al. Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. N Engl J Med. 2016;375:1834–1844.
    • (2016) N Engl J Med , vol.375 , pp. 1834-1844
    • Marso, S.P.1    Bain, S.C.2    Consoli, A.3
  • 48
    • 85041547958 scopus 로고    scopus 로고
    • cited 2017 Nov3
    • Hospital Discharge Rates for Nontraumatic Lower Extremity Amputation by Diabetes Status — united States, 1997 [Internet]. [cited 2017 Nov3]. Available from: https://www.cdc.gov/diabetes/statistics/lea/fig5.htm.
  • 50
    • 85024835007 scopus 로고    scopus 로고
    • SGTL2 inhibitors and amputations in the US FDA Adverse Event Reporting System
    • cited 2017 Nov3
    • Fadini GP, Avogaro A, Schmidt C, et al. SGTL2 inhibitors and amputations in the US FDA Adverse Event Reporting System. Lancet Diabetes Endocrinol [Internet]. 2017;5:680–681. [cited 2017 Nov3]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28733172
    • (2017) Lancet Diabetes Endocrinol [Internet] , vol.5 , pp. 680-681
    • Fadini, G.P.1    Avogaro, A.2    Schmidt, C.3
  • 51
    • 4644300651 scopus 로고    scopus 로고
    • Effectiveness of progressive dose-escalation of exenatide (exendin-4) in reducing dose-limiting side effects in subjects with type 2 diabetes
    • cited 2017 Nov28
    • Fineman MS, Shen LZ, Taylor K, et al. Effectiveness of progressive dose-escalation of exenatide (exendin-4) in reducing dose-limiting side effects in subjects with type 2 diabetes. Diabetes Metab Res Rev [Internet]. 2004 [cited 2017 Nov28];20:411–417. Available from http://doi.wiley.com/10.1002/dmrr.499
    • (2004) Diabetes Metab Res Rev [Internet] , vol.20 , pp. 411-417
    • Fineman, M.S.1    Shen, L.Z.2    Taylor, K.3
  • 52
    • 85032856532 scopus 로고    scopus 로고
    • Reasons for discontinuation of GLP1 receptor agonists: data from a real-world cross-sectional survey of physicians and their patients with type 2 diabetes
    • cited 2017 Nov28
    • Sikirica MV, Martin AA, Wood R, et al. Reasons for discontinuation of GLP1 receptor agonists: data from a real-world cross-sectional survey of physicians and their patients with type 2 diabetes. Diabetes Metab Syndr Obes [Internet]. 2017 [cited 2017 Nov28];10:403–412. Available from http://www.ncbi.nlm.nih.gov/pubmed/29033597
    • (2017) Diabetes Metab Syndr Obes [Internet] , vol.10 , pp. 403-412
    • Sikirica, M.V.1    Martin, A.A.2    Wood, R.3
  • 53
    • 67649666737 scopus 로고    scopus 로고
    • Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
    • cited 2017 Nov28
    • Buse JB, Rosenstock J, Sesti G, et al. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet (London, England) [Internet]. 2009 [cited 2017 Nov28];374:39–47. Available from http://linkinghub.elsevier.com/retrieve/pii/S0140673609606590
    • (2009) Lancet (London, England) [Internet] , vol.374 , pp. 39-47
    • Buse, J.B.1    Rosenstock, J.2    Sesti, G.3
  • 54
    • 84857045922 scopus 로고    scopus 로고
    • The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide
    • cited 2017 Nov28
    • Kanoski SE, Rupprecht LE, Fortin SM, et al. The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide. Neuropharmacology [Internet]. 2012 [cited 2017 Nov28];62:1916–1927. Available from http://linkinghub.elsevier.com/retrieve/pii/S002839081100579X
    • (2012) Neuropharmacology [Internet] , vol.62 , pp. 1916-1927
    • Kanoski, S.E.1    Rupprecht, L.E.2    Fortin, S.M.3
  • 55
    • 84959871979 scopus 로고    scopus 로고
    • Review of head-to-head comparisons of glucagon-like peptide-1 receptor agonists
    • Madsbad S. Review of head-to-head comparisons of glucagon-like peptide-1 receptor agonists. Diabetes Obes Metab [Internet]. 2016;18:317–332. Available from http://www.ncbi.nlm.nih.gov/pubmed/26511102
    • (2016) Diabetes Obes Metab [Internet] , vol.18 , pp. 317-332
    • Madsbad, S.1
  • 56
    • 84937208890 scopus 로고    scopus 로고
    • Sodium-Glucose Linked Transporter 2 (SGLT2) inhibitors in the management of type-2 diabetes: a drug class overview
    • Mosley JF, Smith L, Everton E, et al. Sodium-Glucose Linked Transporter 2 (SGLT2) inhibitors in the management of type-2 diabetes: a drug class overview. Pharm Ther [Internet]. 2015;40:451–462. Available from http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4495872&tool=pmcentrez&rendertype=abstract
    • (2015) Pharm Ther [Internet] , vol.40 , pp. 451-462
    • Mosley, J.F.1    Smith, L.2    Everton, E.3
  • 57
    • 84994874856 scopus 로고    scopus 로고
    • Safety and efficacy of incretin-based therapies in patients with type 2 diabetes mellitus and CKD: a systematic review and meta-analysis
    • Howse PM, Chibrikova LN, Twells LK, et al. Safety and efficacy of incretin-based therapies in patients with type 2 diabetes mellitus and CKD: a systematic review and meta-analysis. Am J Kidney Dis [Internet]. 2016;68:733–742. Available from. DOI:10.1053/j.ajkd.2016.06.014
    • (2016) Am J Kidney Dis [Internet] , vol.68 , pp. 733-742
    • Howse, P.M.1    Chibrikova, L.N.2    Twells, L.K.3
  • 58
    • 85019371670 scopus 로고    scopus 로고
    • SGLT2 inhibitors: a novel choice for the combination therapy in diabetic kidney disease
    • Zou H, Zhou B, Xu G. SGLT2 inhibitors: a novel choice for the combination therapy in diabetic kidney disease. Cardiovasc Diabetol [Internet]. 2017;16:65. Available from http://cardiab.biomedcentral.com/articles/10.1186/s12933-017-0547-1
    • (2017) Cardiovasc Diabetol [Internet] , vol.16 , pp. 65
    • Zou, H.1    Zhou, B.2    Xu, G.3
  • 59
    • 85026498712 scopus 로고    scopus 로고
    • Therapeutic considerations for antihyperglycemic agents in diabetic kidney disease
    • ASN.2016121372
    • Neumiller JJ, Alicic RZ, Tuttle KR. Therapeutic considerations for antihyperglycemic agents in diabetic kidney disease. J Am Soc Nephrol [Internet]. 2017;28:ASN.2016121372. Available from http://m.jasn.asnjournals.org/content/early/2017/06/01/ASN.2016121372.abstract?papetoc%5Cnhttp://www.jasn.org/lookup/doi/10.1681/ASN.2016121372%5Cnwww.jasn.org
    • (2017) J Am Soc Nephrol [Internet] , vol.28
    • Neumiller, J.J.1    Alicic, R.Z.2    Tuttle, K.R.3
  • 60
    • 84962052167 scopus 로고    scopus 로고
    • Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL): A randomized clinical trial
    • et al
    • Davies MJ, Bain SC, Atkin SL, et al. Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL): A randomized clinical trial. Diabetes Care. 2016;39:222–230.
    • (2016) Diabetes Care , vol.39 , pp. 222-230
    • Davies, M.J.1    Bain, S.C.2    Atkin, S.L.3
  • 61
    • 84978839381 scopus 로고    scopus 로고
    • Liraglutide and cardiovascular outcomes in type 2 diabetes
    • et al
    • Marso SP, Daniels GH, Brown-Frandsen K, et al. Liraglutide and cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2016;375:311–322.
    • (2016) N Engl J Med , vol.375 , pp. 311-322
    • Marso, S.P.1    Daniels, G.H.2    Brown-Frandsen, K.3
  • 62
    • 85026394482 scopus 로고    scopus 로고
    • Cardiovascular benefits and safety of non-insulin medications used in the treatment of type 2 diabetes mellitus
    • Nov, et al
    • Yandrapalli S, Jolly G, Horblitt A, et al. Cardiovascular benefits and safety of non-insulin medications used in the treatment of type 2 diabetes mellitus. Postgrad Med. 2017 Nov;129(8):811–821.
    • (2017) Postgrad Med , vol.129 , Issue.8 , pp. 811-821
    • Yandrapalli, S.1    Jolly, G.2    Horblitt, A.3
  • 63
    • 84937208890 scopus 로고    scopus 로고
    • Sodium-Glucose Linked Transporter 2 (SGLT2) inhibitors in the management of type-2 diabetes: a drug class overview
    • et al
    • Mosley JF, Smith L, Everton E, et al. Sodium-Glucose Linked Transporter 2 (SGLT2) inhibitors in the management of type-2 diabetes: a drug class overview. Pharm Ther. 2015;40:451–462.
    • (2015) Pharm Ther , vol.40 , pp. 451-462
    • Mosley, J.F.1    Smith, L.2    Everton, E.3
  • 64
    • 84979895487 scopus 로고    scopus 로고
    • Empagliflozin and progression of kidney disease in type 2 diabetes
    • cited 2017 Dec3
    • Wanner C, Inzucchi SE, Lachin JM, et al. Empagliflozin and progression of kidney disease in type 2 diabetes. N Engl J Med [Internet]. 2016 [cited 2017 Dec3];375:323–334. Available from http://www.ncbi.nlm.nih.gov/pubmed/27299675
    • (2016) N Engl J Med [Internet] , vol.375 , pp. 323-334
    • Wanner, C.1    Inzucchi, S.E.2    Lachin, J.M.3
  • 65
    • 84962135632 scopus 로고    scopus 로고
    • Acute renal effects of the GLP-1 receptor agonist exenatide in overweight type 2 diabetes patients: a randomised, double-blind, placebo-controlled trial
    • et al
    • Tonneijck L, Smits MM, Muskiet MHA, et al. Acute renal effects of the GLP-1 receptor agonist exenatide in overweight type 2 diabetes patients: a randomised, double-blind, placebo-controlled trial. Diabetologia. 2016;59:1412–1421.
    • (2016) Diabetologia , vol.59 , pp. 1412-1421
    • Tonneijck, L.1    Smits, M.M.2    Muskiet, M.H.A.3
  • 66
    • 84906268577 scopus 로고    scopus 로고
    • Effects of GLP-1 in the kidney
    • Skov J. Effects of GLP-1 in the kidney. Rev Endocr Metab Disord. 2014;15:197–207.
    • (2014) Rev Endocr Metab Disord , vol.15 , pp. 197-207
    • Skov, J.1
  • 67
    • 85030447466 scopus 로고    scopus 로고
    • GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes
    • et al
    • Muskiet MHA, Tonneijck L, Smits MM, et al. GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes. Nat Rev Nephrol. 2017.
    • (2017) Nat Rev Nephrol
    • Muskiet, M.H.A.1    Tonneijck, L.2    Smits, M.M.3
  • 68
    • 84908066747 scopus 로고    scopus 로고
    • Update on developments with SGLT2 inhibitors in the management of type 2 diabetes
    • Nauck MA. Update on developments with SGLT2 inhibitors in the management of type 2 diabetes. Drug Des Devel Ther. 2014;8:1335–1351.
    • (2014) Drug Des Devel Ther , vol.8 , pp. 1335-1351
    • Nauck, M.A.1
  • 69
    • 85041497675 scopus 로고    scopus 로고
    • Available from,. [Cited 2017 Nov 7]
    • Invokana prescribing information [Internet]. 2017. [Cited 2017 Nov 7]. Available from: https://www.invokana.com/prescribing-information.pdf.
    • (2017)
  • 70
    • 84980320178 scopus 로고    scopus 로고
    • Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus
    • cited 2017 Nov3
    • Heerspink HJL, Perkins BA, Fitchett DH, et al. Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus. Circulation [Internet]. 2016 [cited 2017 Nov3];134:752–772. Available from http://www.ncbi.nlm.nih.gov/pubmed/27470878
    • (2016) Circulation [Internet] , vol.134 , pp. 752-772
    • Heerspink, H.J.L.1    Perkins, B.A.2    Fitchett, D.H.3
  • 71
    • 85032165629 scopus 로고    scopus 로고
    • Sodium glucose cotransporter-2 inhibition in heart failure
    • Lytvyn Y, Bjornstad P, Udell JA, et al. Sodium glucose cotransporter-2 inhibition in heart failure. Circulation [Internet]. 2017;136:1643. Available from http://circ.ahajournals.org/content/136/17/1643.abstract
    • (2017) Circulation [Internet] , vol.136 , pp. 1643
    • Lytvyn, Y.1    Bjornstad, P.2    Udell, J.A.3
  • 72
    • 84891851923 scopus 로고    scopus 로고
    • Long-term safety and efficacy of empagliflozin, sitagliptin, and metformin
    • et al
    • Ferrannini E, Berk A, Hantel S, et al. Long-term safety and efficacy of empagliflozin, sitagliptin, and metformin. Diabetes Care. 2013;36:4015–4021.
    • (2013) Diabetes Care , vol.36 , pp. 4015-4021
    • Ferrannini, E.1    Berk, A.2    Hantel, S.3
  • 73
    • 84874291673 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise
    • et al
    • Stenlöf K, Cefalu WT, Kim KA, et al. Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise. Diabetes Obes Metab. 2013;15:372–382.
    • (2013) Diabetes Obes Metab , vol.15 , pp. 372-382
    • Stenlöf, K.1    Cefalu, W.T.2    Kim, K.A.3
  • 74
    • 84901455931 scopus 로고    scopus 로고
    • Empaglif lozin as add-on to metformin in patients with type 2 diabetes: A 24-week, randomized, double-blind, placebo-controlled trial
    • et al
    • Häring HU, Merker L, Seewaldt-Becker E, et al. Empaglif lozin as add-on to metformin in patients with type 2 diabetes: A 24-week, randomized, double-blind, placebo-controlled trial. Diabetes Care. 2014;37:1650–1659.
    • (2014) Diabetes Care , vol.37 , pp. 1650-1659
    • Häring, H.U.1    Merker, L.2    Seewaldt-Becker, E.3
  • 75
    • 84903511385 scopus 로고    scopus 로고
    • Improved glucose control with weight loss, lower insulin doses, and no increased hypoglycemia with empagliflozin added to titrated multiple daily injections of insulin in obese inadequately controlled type 2 diabetes
    • et al
    • Rosenstock J, Jelaska A, Frappin G, et al. Improved glucose control with weight loss, lower insulin doses, and no increased hypoglycemia with empagliflozin added to titrated multiple daily injections of insulin in obese inadequately controlled type 2 diabetes. Diabetes Care. 2014;37:1815–1823.
    • (2014) Diabetes Care , vol.37 , pp. 1815-1823
    • Rosenstock, J.1    Jelaska, A.2    Frappin, G.3
  • 76
    • 84892479365 scopus 로고    scopus 로고
    • Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin
    • et al
    • Bolinder J, Ljunggren Ö, Johansson L, et al. Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin. Diabetes Obes Metab. 2014;16:159–169.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 159-169
    • Bolinder, J.1    Ljunggren, Ö.2    Johansson, L.3
  • 77
    • 85020394574 scopus 로고    scopus 로고
    • Effects of SGLT2 inhibitors on UTIs and genital infections in type 2 diabetes mellitus: A systematic review and meta-analysis
    • et al
    • Liu J, Li L, Li S, et al. Effects of SGLT2 inhibitors on UTIs and genital infections in type 2 diabetes mellitus: A systematic review and meta-analysis. Sci Rep. 2017;7:1–11.
    • (2017) Sci Rep , vol.7 , pp. 1-11
    • Liu, J.1    Li, L.2    Li, S.3
  • 78
    • 84945436077 scopus 로고    scopus 로고
    • Determinants of adherence to diabetes treatment
    • et al
    • Larkin AT, Hoffman C, Stevens A, et al. Determinants of adherence to diabetes treatment. J Diabetes. 2015;7:864–871.
    • (2015) J Diabetes , vol.7 , pp. 864-871
    • Larkin, A.T.1    Hoffman, C.2    Stevens, A.3
  • 79
    • 84872065294 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus and the risk of acute pancreatitis
    • et al
    • Yang L, He Z, Tang X, et al. Type 2 diabetes mellitus and the risk of acute pancreatitis. Eur J Gastroenterol Hepatol. 2013;25:225–231.
    • (2013) Eur J Gastroenterol Hepatol , vol.25 , pp. 225-231
    • Yang, L.1    He, Z.2    Tang, X.3
  • 80
    • 84872341897 scopus 로고    scopus 로고
    • Increased variability and abnormalities in pancreatic enzyme concentrations in otherwise asymptomatic subjects with type 2 diabetes
    • et al
    • Malloy J, Gurney K, Shan K, et al. Increased variability and abnormalities in pancreatic enzyme concentrations in otherwise asymptomatic subjects with type 2 diabetes. Diabetes Metab Syndr Obes. 2012;5:419–424.
    • (2012) Diabetes Metab Syndr Obes , vol.5 , pp. 419-424
    • Malloy, J.1    Gurney, K.2    Shan, K.3
  • 81
    • 84887295824 scopus 로고    scopus 로고
    • Pancreatitis-diabetes-pancreatic cancer: summary of an NIDDK-NCI workshop
    • et al
    • Andersen DK, Andren-Sandberg Å, Duell EJ, et al. Pancreatitis-diabetes-pancreatic cancer: summary of an NIDDK-NCI workshop. Pancreas. 2013;42:1227–1237.
    • (2013) Pancreas , vol.42 , pp. 1227-1237
    • Andersen, D.K.1    Andren-Sandberg, Å.2    Duell, E.J.3
  • 82
    • 79959559653 scopus 로고    scopus 로고
    • Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
    • cited 2017 Oct23
    • Elashoff M, Matveyenko AV, Gier B, et al. Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology [Internet]. 2011 [cited 2017 Oct23];141:150–156. Available from http://www.ncbi.nlm.nih.gov/pubmed/21334333
    • (2011) Gastroenterology [Internet] , vol.141 , pp. 150-156
    • Elashoff, M.1    Matveyenko, A.V.2    Gier, B.3
  • 83
    • 84956541198 scopus 로고    scopus 로고
    • Incretins, diabetes, pancreatitis and pancreatic cancer: what the GI specialist needs to know
    • cited 2017 Oct25
    • Forsmark CE. Incretins, diabetes, pancreatitis and pancreatic cancer: what the GI specialist needs to know. Pancreatology [Internet]. 2016;16:10–13. [cited 2017 Oct25]. Available from http://www.ncbi.nlm.nih.gov/pubmed/26795258
    • (2016) Pancreatology [Internet] , vol.16 , pp. 10-13
    • Forsmark, C.E.1
  • 84
    • 84884903039 scopus 로고    scopus 로고
    • The association of pancreatitis with antidiabetic drug use: gaining insight through the FDA pharmacovigilance database
    • cited 2017 Oct25
    • Raschi E, Piccinni C, Poluzzi E, et al. The association of pancreatitis with antidiabetic drug use: gaining insight through the FDA pharmacovigilance database. Acta Diabetol [Internet]. 2013 [cited 2017 Oct25];50:569–577. Available from http://www.ncbi.nlm.nih.gov/pubmed/22008948
    • (2013) Acta Diabetol [Internet] , vol.50 , pp. 569-577
    • Raschi, E.1    Piccinni, C.2    Poluzzi, E.3
  • 85
    • 84878352363 scopus 로고    scopus 로고
    • Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors
    • et al
    • Butler AE, Campbell-Thompson M, Gurlo T, et al. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes. 2013;62:2595–2604.
    • (2013) Diabetes , vol.62 , pp. 2595-2604
    • Butler, A.E.1    Campbell-Thompson, M.2    Gurlo, T.3
  • 86
    • 84903183754 scopus 로고    scopus 로고
    • Reanalysis of study of pancreatic effects of incretin therapy: methodological deficiencies
    • cited 2017 Oct25
    • Bonner-Weir S, In’t Veld PA, Weir GC. Reanalysis of study of pancreatic effects of incretin therapy: methodological deficiencies. Diabetes Obes Metab [Internet]. 2014;16:661–666. [cited 2017 Oct25]. Available from http://www.ncbi.nlm.nih.gov/pubmed/24400596
    • (2014) Diabetes Obes Metab [Internet] , vol.16 , pp. 661-666
    • Bonner-Weir, S.1    In’t Veld, P.A.2    Weir, G.C.3
  • 87
    • 84876063836 scopus 로고    scopus 로고
    • Glucagonlike peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study
    • cited 2017 Oct26
    • Singh S, Chang H-Y, Richards TM, et al. Glucagonlike peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study. JAMA Intern Med [Internet]. 2013 [cited 2017 Oct26];173:534–539. Available from http://archinte.jamanetwork.com/article.aspx?doi=10.1001/jamainternmed.2013.2720
    • (2013) JAMA Intern Med [Internet] , vol.173 , pp. 534-539
    • Singh, S.1    Chang, H.-Y.2    Richards, T.M.3
  • 88
    • 84997521885 scopus 로고    scopus 로고
    • Association between incretin-based drugs and the risk of acute pancreatitis
    • cited 2017 Oct23
    • Azoulay L, Filion KB, Platt RW, et al. Association between incretin-based drugs and the risk of acute pancreatitis. JAMA Intern Med [Internet]. 2016 [cited 2017 Oct23];176:1464. Available from http://www.ncbi.nlm.nih.gov/pubmed/27479930
    • (2016) JAMA Intern Med [Internet] , vol.176 , pp. 1464
    • Azoulay, L.1    Filion, K.B.2    Platt, R.W.3
  • 89
    • 84960154441 scopus 로고    scopus 로고
    • Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study
    • et al
    • Azoulay L, Filion KB, Platt RW, et al. Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study. Bmj. 2016;352:i581.
    • (2016) Bmj , vol.352 , pp. i581
    • Azoulay, L.1    Filion, K.B.2    Platt, R.W.3
  • 90
    • 84942303261 scopus 로고    scopus 로고
    • Incretin-based therapies and acute pancreatitis risk: a systematic review and meta-analysis of observational studies
    • et al
    • Giorda CB, Sacerdote C, Nada E, et al. Incretin-based therapies and acute pancreatitis risk: a systematic review and meta-analysis of observational studies. Endocrine. 2015;48:461–471.
    • (2015) Endocrine , vol.48 , pp. 461-471
    • Giorda, C.B.1    Sacerdote, C.2    Nada, E.3
  • 91
    • 85027063324 scopus 로고    scopus 로고
    • Safety issues with glucagon-like peptide-1 receptor agonists (pancreatitis, pancreatic cancer and cholelithiasis): data from randomized controlled trials. Diabetes, Obes
    • cited 2017 Oct16
    • Monami M, Nreu B, Scatena A, et al. Safety issues with glucagon-like peptide-1 receptor agonists (pancreatitis, pancreatic cancer and cholelithiasis): data from randomized controlled trials. Diabetes, Obes. Metab [Internet]. 2017;19:1233–1241. [cited 2017 Oct16]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28244632
    • (2017) Metab [Internet] , vol.19 , pp. 1233-1241
    • Monami, M.1    Nreu, B.2    Scatena, A.3
  • 92
    • 33847629923 scopus 로고    scopus 로고
    • Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes—a meta-analysis
    • cited, 2017 Nov3
    • Vestergaard P. Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes—a meta-analysis. Osteoporos Int [Internet]. 2007;18:427–444. cited: http://www.ncbi.nlm.nih.gov/pubmed/17068657. 2017 Nov3.
    • (2007) Osteoporos Int [Internet] , vol.18 , pp. 427-444
    • Vestergaard, P.1
  • 93
    • 0035403173 scopus 로고    scopus 로고
    • Diabetes and risk of fracture: the blue mountains eye study
    • cited 2017 Nov3
    • Ivers RQ, Cumming RG, Mitchell P, et al. Diabetes and risk of fracture: the blue mountains eye study. Diabetes Care [Internet]. 2001 [cited 2017 Nov3];24:1198–1203. Available from http://www.ncbi.nlm.nih.gov/pubmed/11423502
    • (2001) Diabetes Care [Internet] , vol.24 , pp. 1198-1203
    • Ivers, R.Q.1    Cumming, R.G.2    Mitchell, P.3
  • 94
    • 34147154970 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-γ agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trial
    • cited 2017 Nov3
    • Grey A, Bolland M, Gamble G, et al. The peroxisome proliferator-activated receptor-γ agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trial. J Clin Endocrinol Metab [Internet]. 2007 [cited 2017 Nov3];92:1305–1310. Available from http://www.ncbi.nlm.nih.gov/pubmed/17264176
    • (2007) J Clin Endocrinol Metab [Internet] , vol.92 , pp. 1305-1310
    • Grey, A.1    Bolland, M.2    Gamble, G.3
  • 95
    • 84953346649 scopus 로고    scopus 로고
    • Glucagon-like peptide-1(GLP-1) receptor agonists: potential to reduce fracture risk in diabetic patients?
    • cited 2017 Nov3
    • Luo G, Liu H, Lu H. Glucagon-like peptide-1(GLP-1) receptor agonists: potential to reduce fracture risk in diabetic patients? Br J Clin Pharmacol [Internet]. 2016;81:78–88. [cited 2017 Nov3]. Available from http://www.ncbi.nlm.nih.gov/pubmed/27099876
    • (2016) Br J Clin Pharmacol [Internet] , vol.81 , pp. 78-88
    • Luo, G.1    Liu, H.2    Lu, H.3
  • 96
    • 84925463236 scopus 로고    scopus 로고
    • Possible adverse effects of SGLT2 inhibitors on bone
    • cited 2017 Nov3
    • Taylor SI, Blau JE, Rother KI. Possible adverse effects of SGLT2 inhibitors on bone. Lancet Diabetes Endocrinol [Internet]. 2015;3:8–10. [cited 2017 Nov3]. Available from http://www.ncbi.nlm.nih.gov/pubmed/25523498
    • (2015) Lancet Diabetes Endocrinol [Internet] , vol.3 , pp. 8-10
    • Taylor, S.I.1    Blau, J.E.2    Rother, K.I.3
  • 97
    • 84954514891 scopus 로고    scopus 로고
    • Effects of canagliflozin on fracture risk in patients with type 2 diabetes mellitus
    • cited 2017 Nov3
    • Watts NB, Bilezikian JP, Usiskin K, et al. Effects of canagliflozin on fracture risk in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab [Internet]. 2016 [cited 2017 Nov3];101:157–166. Available from http://www.ncbi.nlm.nih.gov/pubmed/26580237
    • (2016) J Clin Endocrinol Metab [Internet] , vol.101 , pp. 157-166
    • Watts, N.B.1    Bilezikian, J.P.2    Usiskin, K.3
  • 98
    • 85041508368 scopus 로고    scopus 로고
    • cited 2017 Nov3
    • FDA revises label of diabetes drug canagliflozin (Invokana, Invokamet) to include updates on bone fracture risk and new information on decreased bone mineral density. [cited 2017 Nov3]; Available from: https://www.fda.gov/downloads/Drugs/DrugSafety/UCM461790.pdf.
  • 99
    • 84964334442 scopus 로고    scopus 로고
    • Safety and tolerability of empagliflozin in patients with type 2 diabetes
    • cited 2017 Nov3
    • Kohler S, Salsali A, Hantel S, et al. Safety and tolerability of empagliflozin in patients with type 2 diabetes. Clin Ther [Internet]. 2016 [cited 2017 Nov3];38:1299–1313. Available from http://www.ncbi.nlm.nih.gov/pubmed/27085585
    • (2016) Clin Ther [Internet] , vol.38 , pp. 1299-1313
    • Kohler, S.1    Salsali, A.2    Hantel, S.3
  • 100
    • 84867142771 scopus 로고    scopus 로고
    • Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately controlled type 2 diabetes mellitus on metformin
    • cited 2017 Nov3
    • Ljunggren Ö, Bolinder J, Johansson L, et al. Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately controlled type 2 diabetes mellitus on metformin. Diabetes Obes Metab [Internet]. 2012 [cited 2017 Nov3];14:990–999. Available from http://www.ncbi.nlm.nih.gov/pubmed/22651373
    • (2012) Diabetes Obes Metab [Internet] , vol.14 , pp. 990-999
    • Ljunggren, Ö.1    Bolinder, J.2    Johansson, L.3
  • 101
    • 84962613532 scopus 로고    scopus 로고
    • Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular events, death, and major safety outcomes in adults with type 2 diabetes: A systematic review and meta-analysis
    • Wu JHY, Foote C, Blomster J, et al. Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular events, death, and major safety outcomes in adults with type 2 diabetes: A systematic review and meta-analysis. Lancet Diabetes Endocrinol [Internet]. 2016;4:411–419. Available from http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L609203272%5Cnhttp://dx.doi.org/10.1016/S2213-8587(16)00052-8%5Cnhttp://sfx.library.uu.nl/utrecht?sid=EMBASE&issn=22138595&id=doi:10.1016/S2213-8587(16)00052-8&atitle=Effects+of+sodi
    • (2016) Lancet Diabetes Endocrinol [Internet] , vol.4 , pp. 411-419
    • Wu, J.H.Y.1    Foote, C.2    Blomster, J.3
  • 102
    • 85041525208 scopus 로고    scopus 로고
    • Available from,. [Cited 2017 Nov 3]
    • Victoza prescribing information [Internet]. 2017. [Cited 2017 Nov 3]. Available from: http://www.novo-pi.com/victoza.pdf.
    • (2017)
  • 103
    • 84898954869 scopus 로고    scopus 로고
    • Carcinogenicity risk assessment supports the chronic safety of dapagliflozin, an inhibitor of sodium–glucose co-transporter 2, in the treatment of type 2 diabetes mellitus
    • cited 2017 Dec3
    • Reilly TP, Graziano MJ, Janovitz EB, et al. Carcinogenicity risk assessment supports the chronic safety of dapagliflozin, an inhibitor of sodium–glucose co-transporter 2, in the treatment of type 2 diabetes mellitus. Diabetes Ther [Internet]. 2014 [cited 2017 Dec3];5:73–96. Available from http://www.ncbi.nlm.nih.gov/pubmed/24474422
    • (2014) Diabetes Ther [Internet] , vol.5 , pp. 73-96
    • Reilly, T.P.1    Graziano, M.J.2    Janovitz, E.B.3
  • 104
    • 84921480876 scopus 로고    scopus 로고
    • A review on the relationship between SGLT2 inhibitors and cancer
    • cited 2017 Dec3
    • Lin H-W, Tseng C-H. A review on the relationship between SGLT2 inhibitors and cancer. Int J Endocrinol [Internet]. 2014;2014:1–6. [cited 2017 Dec3]. Available from http://www.ncbi.nlm.nih.gov/pubmed/25254045
    • (2014) Int J Endocrinol [Internet] , vol.2014 , pp. 1-6
    • Lin, H.-W.1    Tseng, C.-H.2
  • 105
    • 77950228684 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonists activate rodent thyroid c-cells causing calcitonin release and C-cell proliferation
    • cited 2017 Dec3
    • Bjerre Knudsen L, Madsen LW, Andersen S, et al. Glucagon-like peptide-1 receptor agonists activate rodent thyroid c-cells causing calcitonin release and C-cell proliferation. Endocrinology [Internet]. 2010 [cited 2017 Dec3];151:1473–1486. Available from http://www.ncbi.nlm.nih.gov/pubmed/20203154
    • (2010) Endocrinology [Internet] , vol.151 , pp. 1473-1486
    • Bjerre Knudsen, L.1    Madsen, L.W.2    Andersen, S.3
  • 106
    • 84994508611 scopus 로고    scopus 로고
    • Exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy (DURATION-8): a 28 week, multicentre, double-blind, phase 3, randomised controlled trial
    • cited 2017 Dec3
    • Frías JP, Guja C, Hardy E, et al. Exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy (DURATION-8): a 28 week, multicentre, double-blind, phase 3, randomised controlled trial. Lancet Diabetes Endocrinol [Internet]. 2016 [cited 2017 Dec3];4:1004–1016. Available from http://www.ncbi.nlm.nih.gov/pubmed/27651331
    • (2016) Lancet Diabetes Endocrinol [Internet] , vol.4 , pp. 1004-1016
    • Frías, J.P.1    Guja, C.2    Hardy, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.