-
2
-
-
0028281773
-
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide i in humans
-
Orskov C, Rabenhøj L, Wettergren A, Kofod H, Holst JJ. Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans. Diabetes 1994;43:535-539
-
(1994)
Diabetes
, vol.43
, pp. 535-539
-
-
Orskov, C.1
Rabenhøj, L.2
Wettergren, A.3
Kofod, H.4
Holst, J.J.5
-
3
-
-
79952310049
-
Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: What is up, what is down?
-
Nauck MA, Vardarli I, Deacon CF, Holst JJ, Meier JJ. Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down? Diabetologia 2011;54:10-18
-
(2011)
Diabetologia
, vol.54
, pp. 10-18
-
-
Nauck, M.A.1
Vardarli, I.2
Deacon, C.F.3
Holst, J.J.4
Meier, J.J.5
-
4
-
-
0036373430
-
Defective amplification of the late phase insulin response to glucose by GIP in obese type II diabetic patients
-
Vilsbøll T, Krarup T, Madsbad S, Holst JJ. Defective amplification of the late phase insulin response to glucose by GIP in obese type II diabetic patients. Diabetologia 2002;45:1111-1119
-
(2002)
Diabetologia
, vol.45
, pp. 1111-1119
-
-
Vilsbøll, T.1
Krarup, T.2
Madsbad, S.3
Holst, J.J.4
-
5
-
-
58149467276
-
Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
-
Højberg PV, Vilsbøll T, Rabøl R, et al. Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes. Diabetologia 2009;52:199-207
-
(2009)
Diabetologia
, vol.52
, pp. 199-207
-
-
Højberg, P.V.1
Vilsbøll, T.2
Rabøl, R.3
-
6
-
-
0036959991
-
Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers
-
Nauck MA, Heimesaat MM, Behle K, et al. Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers. J Clin Endocrinol Metab 2002;87:1239-1246
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1239-1246
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Behle, K.3
-
7
-
-
4344713643
-
Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia
-
Degn KB, Brock B, Juhl CB, et al. Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia. Diabetes 2004;53:2397-2403
-
(2004)
Diabetes
, vol.53
, pp. 2397-2403
-
-
Degn, K.B.1
Brock, B.2
Juhl, C.B.3
-
8
-
-
13344282056
-
A role for glucagon-like peptide-1 in the central regulation of feeding
-
Turton MD, O'Shea D, Gunn I, et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 1996;379:69-72
-
(1996)
Nature
, vol.379
, pp. 69-72
-
-
Turton, M.D.1
O'Shea, D.2
Gunn, I.3
-
9
-
-
0029859220
-
Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats
-
Tang-Christensen M, Larsen PJ, Göke R, et al. Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats. Am J Physiol 1996;271:R848-R856
-
(1996)
Am J Physiol
, vol.271
, pp. R848-R856
-
-
Tang-Christensen, M.1
Larsen, P.J.2
Göke, R.3
-
10
-
-
70450190143
-
Weight loss with liraglutide, a once-daily human glucagonlike peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue
-
LEAD-2 and LEAD-3 Study Groups
-
Jendle J, Nauck MA, Matthews DR, et al.; LEAD-2 and LEAD-3 Study Groups. Weight loss with liraglutide, a once-daily human glucagonlike peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue. Diabetes Obes Metab 2009;11:1163-1172
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 1163-1172
-
-
Jendle, J.1
Nauck, M.A.2
Matthews, D.R.3
-
11
-
-
0030068620
-
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: Effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
-
Willms B, Werner J, Holst JJ, Orskov C, Creutzfeldt W, Nauck MA. Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients. J Clin Endocrinol Metab 1996;81:327-332
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 327-332
-
-
Willms, B.1
Werner, J.2
Holst, J.J.3
Orskov, C.4
Creutzfeldt, W.5
Nauck, M.A.6
-
12
-
-
0037045845
-
Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: A parallel-group study
-
Zander M, Madsbad S, Madsen JL, Holst JJ. Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study. Lancet 2002;359:824-830
-
(2002)
Lancet
, vol.359
, pp. 824-830
-
-
Zander, M.1
Madsbad, S.2
Madsen, J.L.3
Holst, J.J.4
-
13
-
-
77958030736
-
Efficacy and safety of saxagliptin in combination with metformin compared with sitagliptin in combination with metformin in adult patients with type 2 diabetes mellitus
-
Scheen AJ, Charpentier G, Ostgren CJ, Hellqvist A, Gause-Nilsson I. Efficacy and safety of saxagliptin in combination with metformin compared with sitagliptin in combination with metformin in adult patients with type 2 diabetes mellitus. Diabetes Metab Res Rev 2010;26: 540-549
-
(2010)
Diabetes Metab Res Rev
, vol.26
, pp. 540-549
-
-
Scheen, A.J.1
Charpentier, G.2
Ostgren, C.J.3
Hellqvist, A.4
Gause-Nilsson, I.5
-
14
-
-
84924062138
-
Once-weekly trelagliptin versus daily alogliptin in Japanese patients with type 2 diabetes: A randomised, double-blind, phase 3, non-inferiority study
-
Inagaki N, Onouchi H, Maezawa H, Kuroda S, Kaku K. Once-weekly trelagliptin versus daily alogliptin in Japanese patients with type 2 diabetes: a randomised, double-blind, phase 3, non-inferiority study. Lancet Diabetes Endocrinol 2015;3:191-197
-
(2015)
Lancet Diabetes Endocrinol
, vol.3
, pp. 191-197
-
-
Inagaki, N.1
Onouchi, H.2
Maezawa, H.3
Kuroda, S.4
Kaku, K.5
-
15
-
-
34447267513
-
Efficacy and safety of incretin therapy in type 2 diabetes: Systematic review and meta-analysis
-
Amori RE, Lau J, Pittas AG. Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis. JAMA 2007;298:194-206
-
(2007)
JAMA
, vol.298
, pp. 194-206
-
-
Amori, R.E.1
Lau, J.2
Pittas, A.G.3
-
16
-
-
84905472510
-
Comparison of GLP-1 analogues versus sitagliptin in the management of type 2 diabetes: Systematic review and meta-analysis of head-to-head studies
-
Wang T, Gou Z, Wang F, Ma M, Zhai SD. Comparison of GLP-1 analogues versus sitagliptin in the management of type 2 diabetes: systematic review and meta-analysis of head-to-head studies. PLoS One 2014;9:e103798
-
(2014)
PLoS One
, vol.9
, pp. e103798
-
-
Wang, T.1
Gou, Z.2
Wang, F.3
Ma, M.4
Zhai, S.D.5
-
17
-
-
78649686908
-
Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review
-
Deacon CF.Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review. Diabetes Obes Metab 2011;13:7-18
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 7-18
-
-
Deacon, C.F.1
-
18
-
-
34247874561
-
Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes
-
Fonseca V, Schweizer A, Albrecht D, Baron MA, Chang I, Dejager S. Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes. Diabetologia 2007;50:1148-1155
-
(2007)
Diabetologia
, vol.50
, pp. 1148-1155
-
-
Fonseca, V.1
Schweizer, A.2
Albrecht, D.3
Baron, M.A.4
Chang, I.5
Dejager, S.6
-
19
-
-
70450173642
-
Alogliptin added to insulin therapy in patients with type 2 diabetes reduces HbA(1C) without causing weight gain or increased hypoglycaemia
-
Rosenstock J, Rendell MS, Gross JL, Fleck PR, Wilson CA, Mekki Q. Alogliptin added to insulin therapy in patients with type 2 diabetes reduces HbA(1C) without causing weight gain or increased hypoglycaemia. Diabetes ObesMetab 2009;11:1145-1152
-
(2009)
Diabetes ObesMetab
, vol.11
, pp. 1145-1152
-
-
Rosenstock, J.1
Rendell, M.S.2
Gross, J.L.3
Fleck, P.R.4
Wilson, C.A.5
Mekki, Q.6
-
20
-
-
84896731936
-
Pancreatic safety of incretin-based drugs-FDA and EMA assessment
-
Egan AG, Blind E, Dunder K, et al. Pancreatic safety of incretin-based drugs-FDA and EMA assessment. N Engl J Med 2014;370:794-797
-
(2014)
N Engl J Med
, vol.370
, pp. 794-797
-
-
Egan, A.G.1
Blind, E.2
Dunder, K.3
-
21
-
-
84979617391
-
-
U.S. Food and Drug Administration. Drug safety communication. FDA warns that DPP-4 inhibitors for type 2 diabetes may cause severe joint pain [article online] . Accessed 8 December 2015
-
U.S. Food and Drug Administration. Drug safety communication. FDA warns that DPP-4 inhibitors for type 2 diabetes may cause severe joint pain [article online], 2015. Available from http://www.fda.gov/Drugs/DrugSafety/ucm459579 .htm. Accessed 8 December 2015
-
(2015)
-
-
-
22
-
-
84883765959
-
Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus
-
SAVOR-TIMI 53 Steering Committee and Investigators
-
Scirica BM, Bhatt DL, Braunwald E, et al.; SAVOR-TIMI 53 Steering Committee and Investigators. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med 2013;369:1317-1326
-
(2013)
N Engl J Med
, vol.369
, pp. 1317-1326
-
-
Scirica, B.M.1
Bhatt, D.L.2
Braunwald, E.3
-
23
-
-
84883745765
-
Alogliptin after acute coronary syndrome in patients with type 2 diabetes
-
EXAMINE Investigators
-
White WB, Cannon CP, Heller SR, et al.; EXAMINE Investigators. Alogliptin after acute coronary syndrome in patients with type 2 diabetes. N Engl J Med 2013;369:1327-1335
-
(2013)
N Engl J Med
, vol.369
, pp. 1327-1335
-
-
White, W.B.1
Cannon, C.P.2
Heller, S.R.3
-
24
-
-
84937053742
-
Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes
-
TECOS Study Group
-
Green JB, Bethel MA, Armstrong PW, et al.; TECOS Study Group. Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. N Engl J Med 2015;373:232-242
-
(2015)
N Engl J Med
, vol.373
, pp. 232-242
-
-
Green, J.B.1
Bethel, M.A.2
Armstrong, P.W.3
-
25
-
-
84862152967
-
Efficacy of GLP-1 receptor agonists and DPP-4 inhibitors: Meta-analysis and systematic review
-
Aroda VR, Henry RR, Han J, et al. Efficacy of GLP-1 receptor agonists and DPP-4 inhibitors: meta-analysis and systematic review. Clin Ther 2012;34:1247-1258.e22
-
(2012)
Clin Ther
, vol.34
, pp. 1247e22-1247e22
-
-
Aroda, V.R.1
Henry, R.R.2
Han, J.3
-
26
-
-
79953040963
-
An overview of once-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for the future
-
Madsbad S, Kielgast U, Asmar M, Deacon CF, Torekov SS, Holst JJ. An overview of once-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for the future. Diabetes Obes Metab 2011; 13:394-407
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 394-407
-
-
Madsbad, S.1
Kielgast, U.2
Asmar, M.3
Deacon, C.F.4
Torekov, S.S.5
Holst, J.J.6
-
27
-
-
84944517749
-
Efficacy and safety of once-weekly glucagon-like peptide 1 receptor agonists for the management of type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials
-
Karagiannis T, Liakos A, Bekiari E, et al. Efficacy and safety of once-weekly glucagon-like peptide 1 receptor agonists for the management of type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. Diabetes Obes Metab 2015;17:1065-1074
-
(2015)
Diabetes Obes Metab
, vol.17
, pp. 1065-1074
-
-
Karagiannis, T.1
Liakos, A.2
Bekiari, E.3
-
28
-
-
34249869806
-
Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes
-
Vilsbøll T, Zdravkovic M, Le-Thi T, et al. Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes. Diabetes Care 2007;30:1608-1610
-
(2007)
Diabetes Care
, vol.30
, pp. 1608-1610
-
-
Vilsbøll, T.1
Zdravkovic, M.2
Le-Thi, T.3
-
29
-
-
79951962172
-
Glucagon-like peptide-1 analogues for type 2 diabetes
-
Wilding JP, Hardy K. Glucagon-like peptide-1 analogues for type 2 diabetes. BMJ 2011;342:d410
-
(2011)
BMJ
, vol.342
, pp. d410
-
-
Wilding, J.P.1
Hardy, K.2
-
30
-
-
55549136417
-
Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: A randomized, cross-over study
-
DeFronzo RA, Okerson T, Viswanathan P, Guan X, Holcombe JH, MacConell L. Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study. Curr Med Res Opin 2008;24: 2943-2952
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 2943-2952
-
-
DeFronzo, R.A.1
Okerson, T.2
Viswanathan, P.3
Guan, X.4
Holcombe, J.H.5
MacConell, L.6
-
31
-
-
45549101449
-
Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes
-
Cervera A, Wajcberg E, Sriwijitkamol A, et al. Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes. Am J Physiol Endocrinol Metab 2008; 294:E846-E852
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
, pp. E846-E852
-
-
Cervera, A.1
Wajcberg, E.2
Sriwijitkamol, A.3
-
32
-
-
80054090833
-
Effects of exenatide on measures of b-cell function after 3 years in metformin-treated patients with type 2 diabetes
-
Bunck MC, Corńer A, Eliasson B, et al. Effects of exenatide on measures of b-cell function after 3 years in metformin-treated patients with type 2 diabetes. Diabetes Care 2011;34: 2041-2047
-
(2011)
Diabetes Care
, vol.34
, pp. 2041-2047
-
-
Bunck, M.C.1
Corńer, A.2
Eliasson, B.3
-
33
-
-
77952309372
-
Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: A 26-week, randomised, parallel-group, open-label trial
-
1860-LIRA-DPP-4 Study Group
-
Pratley RE, Nauck M, Bailey T, et al.; 1860-LIRA-DPP-4 Study Group. Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial. Lancet 2010;375:1447-1456
-
(2010)
Lancet
, vol.375
, pp. 1447-1456
-
-
Pratley, R.E.1
Nauck, M.2
Bailey, T.3
-
34
-
-
67650066860
-
Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met+TZD)
-
LEAD-4 Study Investigators
-
Zinman B, Gerich J, Buse JB, et al.; LEAD-4 Study Investigators. Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met+TZD). Diabetes Care 2009;32: 1224-1230
-
(2009)
Diabetes Care
, vol.32
, pp. 1224-1230
-
-
Zinman, B.1
Gerich, J.2
Buse, J.B.3
-
35
-
-
77950228684
-
Glucagon-like peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation
-
Bjerre Knudsen L, Madsen LW, Andersen S, et al. Glucagon-like peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation. Endocrinology 2010;151:1473-1486
-
(2010)
Endocrinology
, vol.151
, pp. 1473-1486
-
-
Bjerre Knudsen, L.1
Madsen, L.W.2
Andersen, S.3
-
36
-
-
79952284556
-
GLP-1 and calcitonin concentration in humans: Lack of evidence of calcitonin release from sequential screening in over 5000 subjects with type 2 diabetes or nondiabetic obese subjects treated with the human GLP-1 analog, liraglutide
-
Hegedüs L, Moses AC, Zdravkovic M, Le Thi T, Daniels GH. GLP-1 and calcitonin concentration in humans: lack of evidence of calcitonin release from sequential screening in over 5000 subjects with type 2 diabetes or nondiabetic obese subjects treated with the human GLP-1 analog, liraglutide. J Clin Endocrinol Metab 2011;96:853-860
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 853-860
-
-
Hegedüs, L.1
Moses, A.C.2
Zdravkovic, M.3
Le Thi, T.4
Daniels, G.H.5
-
37
-
-
78650733949
-
Cardiovascular comorbidities of type 2 diabetes mellitus: Defining the potential of glucagonlike peptide-1-based therapies
-
Chilton R, Wyatt J, Nandish S, Oliveros R, Lujan M. Cardiovascular comorbidities of type 2 diabetes mellitus: defining the potential of glucagonlike peptide-1-based therapies. Am J Med 2011;124(Suppl.):S35-S53
-
(2011)
Am J Med
, vol.124
, pp. S35-S53
-
-
Chilton, R.1
Wyatt, J.2
Nandish, S.3
Oliveros, R.4
Lujan, M.5
-
38
-
-
84948740668
-
Lixisenatide in patients with type 2 diabetes and acute coronary syndrome
-
ELIXA Investigators
-
Pfeffer MA, Claggett B, Diaz R, et al.; ELIXA Investigators. Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. N Engl J Med 2015;373:2247-2257
-
(2015)
N Engl J Med
, vol.373
, pp. 2247-2257
-
-
Pfeffer, M.A.1
Claggett, B.2
Diaz, R.3
-
39
-
-
0023275573
-
Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats
-
Rossetti L, Smith D, ShulmanGI, Papachristou D, DeFronzo RA. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest 1987;79: 1510-1515
-
(1987)
J Clin Invest
, vol.79
, pp. 1510-1515
-
-
Rossetti, L.1
Smith, D.2
Shulman, G.I.3
Papachristou, D.4
DeFronzo, R.A.5
-
40
-
-
80052362968
-
Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes
-
Abdul-Ghani MA, Norton L, Defronzo RA. Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes. Endocr Rev 2011;32:515-531
-
(2011)
Endocr Rev
, vol.32
, pp. 515-531
-
-
Abdul-Ghani, M.A.1
Norton, L.2
Defronzo, R.A.3
-
41
-
-
78651349221
-
Biology of human sodium glucose transporters
-
Wright EM, Loo DD, Hirayama BA. Biology of human sodium glucose transporters. Physiol Rev 2011;91:733-794
-
(2011)
Physiol Rev
, vol.91
, pp. 733-794
-
-
Wright, E.M.1
Loo, D.D.2
Hirayama, B.A.3
-
42
-
-
84937763347
-
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
-
Bonner C, Kerr-Conte J, Gmyr V, et al. Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. Nat Med 2015;21:512-517
-
(2015)
Nat Med
, vol.21
, pp. 512-517
-
-
Bonner, C.1
Kerr-Conte, J.2
Gmyr, V.3
-
43
-
-
0034997336
-
Renal Na(+)-glucose cotransporters
-
Wright EM. Renal Na(+)-glucose cotransporters. Am J Physiol Renal Physiol 2001;280: F10-F18
-
(2001)
Am J Physiol Renal Physiol
, vol.280
, pp. F10-F18
-
-
Wright, E.M.1
-
44
-
-
77953181310
-
Dapagliflozin treatment in patients with different stages of type 2 diabetes mellitus: Effects on glycaemic control and body weight
-
Zhang L, Feng Y, List J, Kasichayanula S, Pfister M. Dapagliflozin treatment in patients with different stages of type 2 diabetes mellitus: effects on glycaemic control and body weight. Diabetes Obes Metab 2010;12:510-516
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 510-516
-
-
Zhang, L.1
Feng, Y.2
List, J.3
Kasichayanula, S.4
Pfister, M.5
-
45
-
-
84898791935
-
Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: A meta-analysis of randomized clinical trials
-
Monami M, Nardini C, Mannucci E. Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials. Diabetes ObesMetab 2014;16:457-466
-
(2014)
Diabetes ObesMetab
, vol.16
, pp. 457-466
-
-
Monami, M.1
Nardini, C.2
Mannucci, E.3
-
46
-
-
84882251091
-
Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: A systematic reviewandmetaanalysis
-
Vasilakou D, Karagiannis T, Athanasiadou E, et al. Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic reviewandmetaanalysis. Ann Intern Med 2013;159:262-274
-
(2013)
Ann Intern Med
, vol.159
, pp. 262-274
-
-
Vasilakou, D.1
Karagiannis, T.2
Athanasiadou, E.3
-
47
-
-
84934288630
-
Safety profile of dapagliflozin for type 2 diabetes: Pooled analysis of clinical studies for overall safety and rare events
-
Ptaszynska A, Johnsson KM, Parikh SJ, de Bruin TW, Apanovitch AM, List JF. Safety profile of dapagliflozin for type 2 diabetes: pooled analysis of clinical studies for overall safety and rare events. Drug Saf 2014;37:815-829
-
(2014)
Drug Saf
, vol.37
, pp. 815-829
-
-
Ptaszynska, A.1
Johnsson, K.M.2
Parikh, S.J.3
De Bruin, T.W.4
Apanovitch, A.M.5
List, J.F.6
-
48
-
-
84914689445
-
A safety evaluation of canagliflozin: A first-in-class treatment for type 2 diabetes
-
Boyle LD, Wilding JP. A safety evaluation of canagliflozin: a first-in-class treatment for type 2 diabetes. Expert Opin Drug Saf 2014;13: 1535-1544
-
(2014)
Expert Opin Drug Saf
, vol.13
, pp. 1535-1544
-
-
Boyle, L.D.1
Wilding, J.P.2
-
49
-
-
84899105421
-
Sodium-glucose cotransporter 2 inhibition and glycemic control in type 1 diabetes: Results of an 8-week open-label proof-of-concept trial
-
Perkins BA, Cherney DZ, Partridge H, et al. Sodium-glucose cotransporter 2 inhibition and glycemic control in type 1 diabetes: results of an 8-week open-label proof-of-concept trial. Diabetes Care 2014;37:1480-1483
-
(2014)
Diabetes Care
, vol.37
, pp. 1480-1483
-
-
Perkins, B.A.1
Cherney, D.Z.2
Partridge, H.3
-
50
-
-
84933523949
-
Characterisation of glomerular haemodynamic responses to SGLT2 inhibition in patients with type 1 diabetes and renal hyperfiltration
-
Skrtíc M, Yang GK, Perkins BA, et al. Characterisation of glomerular haemodynamic responses to SGLT2 inhibition in patients with type 1 diabetes and renal hyperfiltration. Diabetologia 2014;57:2599-2602
-
(2014)
Diabetologia
, vol.57
, pp. 2599-2602
-
-
Skrtíc, M.1
Yang, G.K.2
Perkins, B.A.3
-
51
-
-
84962339296
-
Euglycemic diabetic ketoacidosis: A potential complication of treatment with sodium-glucose cotransporter 2 inhibition
-
Peters AL, Buschur EO, Buse JB, Cohan P, Diner JC, Hirsch IB. Euglycemic diabetic ketoacidosis: a potential complication of treatment with sodium-glucose cotransporter 2 inhibition. Diabetes Care 2015;38:1687-1693
-
(2015)
Diabetes Care
, vol.38
, pp. 1687-1693
-
-
Peters, A.L.1
Buschur, E.O.2
Buse, J.B.3
Cohan, P.4
Diner, J.C.5
Hirsch, I.B.6
-
54
-
-
0020567452
-
Role of glucagon in enhancing ketone body production in ketotic diabetic man
-
Keller U, Schnell H, Sonnenberg GE, Gerber PP, Stauffacher W. Role of glucagon in enhancing ketone body production in ketotic diabetic man. Diabetes 1983;32:387-391
-
(1983)
Diabetes
, vol.32
, pp. 387-391
-
-
Keller, U.1
Schnell, H.2
Sonnenberg, G.E.3
Gerber, P.P.4
Stauffacher, W.5
-
55
-
-
84897394040
-
Longterm study of patients with type 2 diabetes and moderate renal impairment shows that dapagliflozin reduces weight and blood pressure but does not improve glycemic control
-
Kohan DE, Fioretto P, Tang W, List JF. Longterm study of patients with type 2 diabetes and moderate renal impairment shows that dapagliflozin reduces weight and blood pressure but does not improve glycemic control. Kidney Int 2014;85:962-971
-
(2014)
Kidney Int
, vol.85
, pp. 962-971
-
-
Kohan, D.E.1
Fioretto, P.2
Tang, W.3
List, J.F.4
-
56
-
-
84954514891
-
Effects of canagliflozin on fracture risk in patients with type 2 diabetes mellitus
-
Watts NB, Bilezikian JP, Usiskin K, et al. Effects of canagliflozin on fracture risk in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 2016;101:157-166
-
(2016)
J Clin Endocrinol Metab
, vol.101
, pp. 157-166
-
-
Watts, N.B.1
Bilezikian, J.P.2
Usiskin, K.3
-
58
-
-
84892479365
-
Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin
-
Bolinder J, Ljunggren O, Johansson L, et al. Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin. Diabetes Obes Metab 2014;16:159-169
-
(2014)
Diabetes Obes Metab
, vol.16
, pp. 159-169
-
-
Bolinder, J.1
Ljunggren, O.2
Johansson, L.3
-
59
-
-
84885954870
-
Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: A randomised, double-blind, placebo-controlled, phase 3 trial
-
EMPAREG MONO trial investigators
-
Roden M, Weng J, Eilbracht J, et al.; EMPAREG MONO trial investigators. Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Diabetes Endocrinol 2013;1: 208-219
-
(2013)
Lancet Diabetes Endocrinol
, vol.1
, pp. 208-219
-
-
Roden, M.1
Weng, J.2
Eilbracht, J.3
-
60
-
-
84887997289
-
Efficacy and safety of canagliflozin compared with placebo and sitagliptin in patientswith type 2 diabetes on background metformin monotherapy: A randomised trial
-
Lavalle-Gonźalez FJ, Januszewicz A, Davidson J, et al. Efficacy and safety of canagliflozin compared with placebo and sitagliptin in patientswith type 2 diabetes on background metformin monotherapy: a randomised trial. Diabetologia 2013;56: 2582-2592
-
(2013)
Diabetologia
, vol.56
, pp. 2582-2592
-
-
Lavalle-Gonźalez, F.J.1
Januszewicz, A.2
Davidson, J.3
-
61
-
-
84891784200
-
Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea: A 52-week randomized trial
-
Schernthaner G, Gross JL, Rosenstock J, et al. Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea: a 52-week randomized trial. Diabetes Care 2013;36:2508-2515
-
(2013)
Diabetes Care
, vol.36
, pp. 2508-2515
-
-
Schernthaner, G.1
Gross, J.L.2
Rosenstock, J.3
-
62
-
-
84884167643
-
Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial
-
Cefalu WT, Leiter LA, Yoon K-H, et al. Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial. Lancet 2013;382: 941-950
-
(2013)
Lancet
, vol.382
, pp. 941-950
-
-
Cefalu, W.T.1
Leiter, L.A.2
Yoon, K.-H.3
-
63
-
-
84908332537
-
Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: A 104-week randomised, active-controlled, double-blind, phase 3 trial
-
EMPA-REG H2H-SU trial investigators
-
Ridderstrale M, Andersen KR, Zeller C, Kim G, Woerle HJ, Broedl UC; EMPA-REG H2H-SU trial investigators. Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol 2014;2:691-700
-
(2014)
Lancet Diabetes Endocrinol
, vol.2
, pp. 691-700
-
-
Ridderstrale, M.1
Andersen, K.R.2
Zeller, C.3
Kim, G.4
Woerle, H.J.5
Broedl, U.C.6
-
64
-
-
80155124676
-
Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: A randomized, 52-week, double-blind, activecontrolled noninferiority trial
-
Nauck MA, Del Prato S, Meier JJ, et al. Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: a randomized, 52-week, double-blind, activecontrolled noninferiority trial. Diabetes Care 2011;34:2015-2022
-
(2011)
Diabetes Care
, vol.34
, pp. 2015-2022
-
-
Nauck, M.A.1
Del Prato, S.2
Meier, J.J.3
-
65
-
-
84928426587
-
Long-term glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as addon therapy to metformin in patients with type 2 diabetes: 4-year data
-
Del Prato S, Nauck M, Duŕan-Garcia S, et al. Long-term glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as addon therapy to metformin in patients with type 2 diabetes: 4-year data. Diabetes Obes Metab 2015;17:581-590
-
(2015)
Diabetes Obes Metab
, vol.17
, pp. 581-590
-
-
Del Prato, S.1
Nauck, M.2
Duŕan-Garcia, S.3
-
66
-
-
0032511583
-
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
-
UK Prospective Diabetes Study (UKPDS) Group
-
UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-853
-
(1998)
Lancet
, vol.352
, pp. 837-853
-
-
-
67
-
-
29144453326
-
Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes
-
Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDiC) Study Research Group
-
Nathan DM, Cleary PA, Backlund JY, et al.; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDiC) Study Research Group. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med 2005;353:2643-2653
-
(2005)
N Engl J Med
, vol.353
, pp. 2643-2653
-
-
Nathan, D.M.1
Cleary, P.A.2
Backlund, J.Y.3
-
68
-
-
0034071036
-
Long-term results of the Kumamoto Study on optimal diabetes control in type 2 diabetic patients
-
Shichiri M, Kishikawa H, Ohkubo Y, Wake N. Long-term results of the Kumamoto Study on optimal diabetes control in type 2 diabetic patients. Diabetes Care 2000;23(Suppl. 2):B21-B29
-
(2000)
Diabetes Care
, vol.23
, pp. B21-B29
-
-
Shichiri, M.1
Kishikawa, H.2
Ohkubo, Y.3
Wake, N.4
-
69
-
-
45149133036
-
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
-
ADVANCE Collaborative Group
-
Patel A, MacMahon S, Chalmers J, et al.; ADVANCE Collaborative Group. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008;358:2560-2572
-
(2008)
N Engl J Med
, vol.358
, pp. 2560-2572
-
-
Patel, A.1
MacMahon, S.2
Chalmers, J.3
-
70
-
-
45149131667
-
Effects of intensive glucose lowering in type 2 diabetes
-
Action to Control Cardiovascular Risk in Diabetes Study Group
-
Gerstein HC, Miller ME, Byington RP, et al.; Action to Control Cardiovascular Risk in Diabetes Study Group. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 2008;358:2545-2559
-
(2008)
N Engl J Med
, vol.358
, pp. 2545-2559
-
-
Gerstein, H.C.1
Miller, M.E.2
Byington, R.P.3
-
71
-
-
58149389215
-
Glucose control and vascular complications in veterans with type 2 diabetes
-
VADT Investigators
-
Duckworth W, Abraira C, Moritz T, et al.; VADT Investigators. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009;360:129-139
-
(2009)
N Engl J Med
, vol.360
, pp. 129-139
-
-
Duckworth, W.1
Abraira, C.2
Moritz, T.3
-
72
-
-
84941243068
-
Impact of glucoselowering drugs on cardiovascular disease in type 2 diabetes
-
Ferrannini E,DeFronzo RA. Impact of glucoselowering drugs on cardiovascular disease in type 2 diabetes. Eur Heart J 2015;36:2288-2296
-
(2015)
Eur Heart J
, vol.36
, pp. 2288-2296
-
-
Ferrannini, E.1
DeFronzo, R.A.2
-
73
-
-
77952778197
-
The A1C and ABCD of glycaemia management in type 2 diabetes: A physician's personalized approach
-
Pozzilli P, Leslie RD, Chan J, et al. The A1C and ABCD of glycaemia management in type 2 diabetes: a physician's personalized approach. Diabetes Metab Res Rev 2010;26:239-244
-
(2010)
Diabetes Metab Res Rev
, vol.26
, pp. 239-244
-
-
Pozzilli, P.1
Leslie, R.D.2
Chan, J.3
-
74
-
-
84866268783
-
Management of hyperglycemia in type 2 diabetes: A patient-centered approach: Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
-
American Diabetes Association (ADA); European Association for the Study of Diabetes (EASD)
-
Inzucchi SE, Bergenstal RM, Buse JB, et al.; American Diabetes Association (ADA); European Association for the Study of Diabetes (EASD). Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2012;35:1364-1379
-
(2012)
Diabetes Care
, vol.35
, pp. 1364-1379
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
75
-
-
84979497046
-
-
National Institute for Health and Care Excellence. Type 2 diabetes in adults: management NICE guideline (NG28) [article online] . Accessed 8 December 2015
-
National Institute for Health and Care Excellence. Type 2 diabetes in adults: management NICE guideline (NG28) [article online], 2015. Available from https://www.nice.org.uk/guidance/ng28. Accessed 8 December 2015
-
(2015)
-
-
-
76
-
-
84964203025
-
Initial combination therapy with metformin, pioglitazone and exenatide is more effective than sequential add-on therapy in subjects with new-onset diabetes Results from the Efficacy and Durability of Initial Combination Therapy for Type 2 Diabetes (EDiCT): A randomized trial
-
Abdul-Ghani MA, Puckett C, Triplitt C, et al. Initial combination therapy with metformin, pioglitazone and exenatide is more effective than sequential add-on therapy in subjects with new-onset diabetes. Results from the Efficacy and Durability of Initial Combination Therapy for Type 2 Diabetes (EDiCT): a randomized trial. Diabetes Obes Metab 2015; 17:268-275
-
(2015)
Diabetes Obes Metab
, vol.17
, pp. 268-275
-
-
Abdul-Ghani, M.A.1
Puckett, C.2
Triplitt, C.3
-
77
-
-
84876269606
-
Insulin vs GLP-1 analogues in poorly controlled type 2 diabetic subjects on oral therapy: Ameta-analysis
-
Abdul-Ghani MA, Williams K, Kanat M, Altuntas Y, DeFronzo RA. Insulin vs GLP-1 analogues in poorly controlled type 2 diabetic subjects on oral therapy: ameta-analysis. J Endocrinol Invest 2013;36:168-173
-
(2013)
J Endocrinol Invest
, vol.36
, pp. 168-173
-
-
Abdul-Ghani, M.A.1
Williams, K.2
Kanat, M.3
Altuntas, Y.4
DeFronzo, R.A.5
-
78
-
-
38549162147
-
Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years
-
Klonoff DC, Buse JB, Nielsen LL, et al. Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years. Curr Med Res Opin 2008;24:275-286
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 275-286
-
-
Klonoff, D.C.1
Buse, J.B.2
Nielsen, L.L.3
-
79
-
-
84904360390
-
Efficacy and safety of dulaglutide monotherapy versus metformin in type 2 diabetes in a randomized controlled trial (AWARD-3)
-
Umpierrez G, Tofé Povedano S, Ṕerez Manghi F, Shurzinske L, Pechtner V. Efficacy and safety of dulaglutide monotherapy versus metformin in type 2 diabetes in a randomized controlled trial (AWARD-3). Diabetes Care 2014; 37:2168-2176
-
(2014)
Diabetes Care
, vol.37
, pp. 2168-2176
-
-
Umpierrez, G.1
Tofé Povedano, S.2
Ṕerez Manghi, F.3
Shurzinske, L.4
Pechtner, V.5
-
80
-
-
84862302997
-
Exenatide twice daily versus glimepiride for prevention of glycaemic deterioration in patients with type 2 diabetes with metformin failure (EUREXA): An open-label, randomised controlled trial
-
Gallwitz B, Guzman J,Dotta F, et al. Exenatide twice daily versus glimepiride for prevention of glycaemic deterioration in patients with type 2 diabetes with metformin failure (EUREXA): an open-label, randomised controlled trial. Lancet 2012;379:2270-2278
-
(2012)
Lancet
, vol.379
, pp. 2270-2278
-
-
Gallwitz, B.1
Guzman, J.2
Dotta, F.3
-
81
-
-
77649254732
-
Secondary failure of metformin monotherapy in clinical practice
-
Brown JB, Conner C, Nichols GA. Secondary failure of metformin monotherapy in clinical practice. Diabetes Care 2010;33:501-506
-
(2010)
Diabetes Care
, vol.33
, pp. 501-506
-
-
Brown, J.B.1
Conner, C.2
Nichols, G.A.3
-
82
-
-
33845405222
-
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
-
ADOPT Study Group
-
Kahn SE, Haffner SM, Heise MA, et al.; ADOPT Study Group. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 2006;355:2427-2443
-
(2006)
N Engl J Med
, vol.355
, pp. 2427-2443
-
-
Kahn, S.E.1
Haffner, S.M.2
Heise, M.A.3
-
83
-
-
62449169287
-
Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: The LEAD (Liraglutide Effect and Action in Diabetes)-2 study
-
LEAD-2 Study Group
-
NauckM, Frid A, Hermansen K, et al.; LEAD-2 Study Group. Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (Liraglutide Effect and Action in Diabetes)-2 study. Diabetes Care 2009;32:84-90
-
(2009)
Diabetes Care
, vol.32
, pp. 84-90
-
-
Nauck, M.1
Frid, A.2
Hermansen, K.3
-
84
-
-
79951906623
-
Liraglutide, a once-daily human glucagon-like peptide 1 analogue, provides sustained improvements in glycaemic control and weight for 2 years as monotherapy compared with glimepiride in patients with type 2 diabetes
-
LEAD-3 (Mono) Study Group
-
Garber A, Henry RR, Ratner R, Hale P, Chang CT, Bode B; LEAD-3 (Mono) Study Group. Liraglutide, a once-daily human glucagon-like peptide 1 analogue, provides sustained improvements in glycaemic control and weight for 2 years as monotherapy compared with glimepiride in patients with type 2 diabetes. Diabetes Obes Metab 2011;13:348-356
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 348-356
-
-
Garber, A.1
Henry, R.R.2
Ratner, R.3
Hale, P.4
Chang, C.T.5
Bode, B.6
-
85
-
-
77949356196
-
A comparison of efficacy and safety of vildagliptin and gliclazide in combination with metformin in patients with type 2 diabetes inadequately controlled with metformin alone: A 52-week, randomized study
-
Filozof C, Gautier JF. A comparison of efficacy and safety of vildagliptin and gliclazide in combination with metformin in patients with type 2 diabetes inadequately controlled with metformin alone: a 52-week, randomized study. Diabet Med 2010;27:318-326
-
(2010)
Diabet Med
, vol.27
, pp. 318-326
-
-
Filozof, C.1
Gautier, J.F.2
-
86
-
-
58149330590
-
Fifty-two-week efficacy and safety of vildagliptin vs. Glimepiride in patients with type 2 diabetes mellitus inadequately controlled on metformin monotherapy
-
Ferrannini E, Fonseca V, Zinman B, et al. Fifty-two-week efficacy and safety of vildagliptin vs. glimepiride in patients with type 2 diabetes mellitus inadequately controlled on metformin monotherapy. Diabetes Obes Metab 2009;11: 157-166
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 157-166
-
-
Ferrannini, E.1
Fonseca, V.2
Zinman, B.3
-
87
-
-
84904963065
-
HARMONY 3: 104-week randomized, double-blind, placeboand active-controlled trial assessing the efficacy and safety of albiglutide compared with placebo, sitagliptin, and glimepiride in patients with type 2 diabetes taking metformin
-
HARMONY 3 Study Group
-
Ahŕen B, Johnson SL, Stewart M, et al.; HARMONY 3 Study Group. HARMONY 3: 104-week randomized, double-blind, placeboand active-controlled trial assessing the efficacy and safety of albiglutide compared with placebo, sitagliptin, and glimepiride in patients with type 2 diabetes taking metformin. Diabetes Care 2014;37:2141-2148
-
(2014)
Diabetes Care
, vol.37
, pp. 2141-2148
-
-
Ahŕen, B.1
Johnson, S.L.2
Stewart, M.3
-
88
-
-
84919999219
-
Management of hyperglycemia in type 2 diabetes, 2015: A patient-centered approach: Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2015; 38:140-149
-
(2015)
Diabetes Care
, vol.38
, pp. 140-149
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
89
-
-
79551615182
-
Use of twice-daily exenatide in basal insulin-treated patients with type 2 diabetes: A randomized, controlled trial
-
Buse JB, Bergenstal RM, Glass LC, et al. Use of twice-daily exenatide in basal insulin-treated patients with type 2 diabetes: a randomized, controlled trial. Ann Intern Med 2011;154: 103-112
-
(2011)
Ann Intern Med
, vol.154
, pp. 103-112
-
-
Buse, J.B.1
Bergenstal, R.M.2
Glass, L.C.3
-
90
-
-
84919344081
-
Glucagon-like peptide-1 receptor agonist and basal insulin combination treatment for the management of type 2 diabetes: A systematic review and meta-analysis
-
Eng C, Kramer CK, Zinman B, Retnakaran R. Glucagon-like peptide-1 receptor agonist and basal insulin combination treatment for the management of type 2 diabetes: a systematic review and meta-analysis. Lancet 2014;384: 2228-2234
-
(2014)
Lancet
, vol.384
, pp. 2228-2234
-
-
Eng, C.1
Kramer, C.K.2
Zinman, B.3
Retnakaran, R.4
-
91
-
-
84908164432
-
Glucagon-like peptide 1 receptor agonist or bolus insulin with optimized basal insulin in type 2 diabetes
-
4B Study Group
-
Diamant M, Nauck MA, Shaginian R, et al.; 4B Study Group. Glucagon-like peptide 1 receptor agonist or bolus insulin with optimized basal insulin in type 2 diabetes. Diabetes Care 2014; 37:2763-2773
-
(2014)
Diabetes Care
, vol.37
, pp. 2763-2773
-
-
Diamant, M.1
Nauck, M.A.2
Shaginian, R.3
-
92
-
-
84858323889
-
Long-term efficacy of dapagliflozin in patients with type 2 diabetesmellitus receiving high doses of insulin: A randomized trial
-
Dapagliflozin 006 Study Group
-
Wilding JP,WooV, SolerNG, et al.;Dapagliflozin 006 Study Group. Long-term efficacy of dapagliflozin in patients with type 2 diabetesmellitus receiving high doses of insulin: a randomized trial. Ann Intern Med 2012;156:405-415
-
(2012)
Ann Intern Med
, vol.156
, pp. 405-415
-
-
Wilding, J.P.1
Woo, V.2
Soler, N.G.3
-
93
-
-
84930841315
-
American Association of Clinical Endocrinologists and American College of Endocrinology-clinical practice guidelines for developing a diabetes mellitus comprehensive care plan-2015
-
Handelsman Y, Bloomgarden ZT, Grunberger G, et al. American Association of Clinical Endocrinologists and American College of Endocrinology-clinical practice guidelines for developing a diabetes mellitus comprehensive care plan-2015. Endocr Pract 2015;21(Suppl. 1): 1-87
-
(2015)
Endocr Pract
, vol.21
, pp. 1-87
-
-
Handelsman, Y.1
Bloomgarden, Z.T.2
Grunberger, G.3
-
94
-
-
67149146438
-
Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): A multicentre, randomised, open-label trial
-
RECORD Study Team
-
Home PD, Pocock SJ, Beck-Nielsen H, et al.; RECORD Study Team. Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial. Lancet 2009;373:2125-2135
-
(2009)
Lancet
, vol.373
, pp. 2125-2135
-
-
Home, P.D.1
Pocock, S.J.2
Beck-Nielsen, H.3
-
95
-
-
84944800184
-
Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
-
EMPA-REGOUTCOMEInvestigators
-
Zinman B, Wanner C, Lachin JM, et al.; EMPA-REGOUTCOMEInvestigators. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med 2015;373:2117-2128
-
(2015)
N Engl J Med
, vol.373
, pp. 2117-2128
-
-
Zinman, B.1
Wanner, C.2
Lachin, J.M.3
-
96
-
-
0024026298
-
Lilly lecture 1987 the triumvirate: Beta-cell,muscle, liver A collusion responsible for NIDDM
-
DeFronzo RA. Lilly lecture 1987. The triumvirate: beta-cell,muscle, liver. A collusion responsible for NIDDM. Diabetes 1988;37:667-687
-
(1988)
Diabetes
, vol.37
, pp. 667-687
-
-
DeFronzo, R.A.1
-
97
-
-
64649104158
-
Banting lecture from the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus
-
Defronzo RA. Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes 2009;58:773-795
-
(2009)
Diabetes
, vol.58
, pp. 773-795
-
-
Defronzo, R.A.1
-
98
-
-
84928176749
-
Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin
-
DeFronzo RA, Lewin A, Patel S, et al. Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin. Diabetes Care 2015;38:384-393
-
(2015)
Diabetes Care
, vol.38
, pp. 384-393
-
-
DeFronzo, R.A.1
Lewin, A.2
Patel, S.3
-
99
-
-
84928201032
-
Dual addon therapy in type 2 diabetes poorly controlled with metformin monotherapy: A randomized doubleblind trial of saxagliptin plus dapagliflozin addition versus single addition of saxagliptin or dapagliflozin to metformin
-
Rosenstock J, Hansen L, Zee P, et al. Dual addon therapy in type 2 diabetes poorly controlled with metformin monotherapy: a randomized doubleblind trial of saxagliptin plus dapagliflozin addition versus single addition of saxagliptin or dapagliflozin to metformin. Diabetes Care 2015;38:376-383
-
(2015)
Diabetes Care
, vol.38
, pp. 376-383
-
-
Rosenstock, J.1
Hansen, L.2
Zee, P.3
-
100
-
-
84893872877
-
Metabolic response tosodium-glucose cotransporter2 inhibition in type 2 diabetic patients
-
Ferrannini E,Muscelli E, Frascerra S, et al.Metabolic response tosodium-glucose cotransporter2 inhibition in type 2 diabetic patients. J Clin Invest 2014;124:499-508.
-
(2014)
J Clin Invest
, vol.124
, pp. 499-508
-
-
Ferrannini, E.1
Muscelli, E.2
Frascerra, S.3
-
101
-
-
84893827104
-
Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production
-
Merovci A, Solis-Herrera C, Daniele G, et al. Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production. J Clin Invest 2014;124:509-514
-
(2014)
J Clin Invest
, vol.124
, pp. 509-514
-
-
Merovci, A.1
Solis-Herrera, C.2
Daniele, G.3
-
102
-
-
77956921439
-
Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: A randomized, double-blind, placebo-controlled, phase 3 trial
-
Ferrannini E, Ramos SJ, Salsali A, Tang W, List JF. Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial. Diabetes Care 2010;33:2217-2224
-
(2010)
Diabetes Care
, vol.33
, pp. 2217-2224
-
-
Ferrannini, E.1
Ramos, S.J.2
Salsali, A.3
Tang, W.4
List, J.F.5
-
103
-
-
84918531200
-
Sodium-glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy
-
?Skrtíc M, Cherney DZ. Sodium-glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy. Curr Opin Nephrol Hypertens 2015;24:96-103
-
(2015)
Curr Opin Nephrol Hypertens
, vol.24
, pp. 96-103
-
-
Skrtíc, M.1
Cherney, D.Z.2
-
104
-
-
84893214045
-
Renal hemodynamic effect of sodiumglucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus
-
Cherney DZI, Perkins BA, Soleymanlou N, et al. Renal hemodynamic effect of sodiumglucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus. Circulation 2014; 129:587-597
-
(2014)
Circulation
, vol.129
, pp. 587-597
-
-
Cherney, D.Z.I.1
Perkins, B.A.2
Soleymanlou, N.3
-
105
-
-
84873497173
-
Effects of SGLT2 inhibition in human kidney proximal tubular cells-renoprotection in diabetic nephropathy?
-
Panchapakesan U, Pegg K, Gross S, et al. Effects of SGLT2 inhibition in human kidney proximal tubular cells-renoprotection in diabetic nephropathy? PLoS One 2013;8:e54442
-
(2013)
PLoS One
, vol.8
, pp. e54442
-
-
Panchapakesan, U.1
Pegg, K.2
Gross, S.3
-
106
-
-
85006124911
-
Renoprotective effects of combined SGLT2 and ACE inhibitor therapy in diabetic Dahl S rats
-
Kojima N, Williams JM, Slaughter TN, et al. Renoprotective effects of combined SGLT2 and ACE inhibitor therapy in diabetic Dahl S rats. Physiol Rep 2015;3:3
-
(2015)
Physiol Rep
, vol.3
, pp. 3
-
-
Kojima, N.1
Williams, J.M.2
Slaughter, T.N.3
-
107
-
-
84964228541
-
Empagliflozin and cardiovascular outcomes in patients with type 2 diabetes and chronic kidney disease (Abstract)
-
Wanner CLJ, Fitchett DH, Inzucchi SE, et al. Empagliflozin and cardiovascular outcomes in patients with type 2 diabetes and chronic kidney disease (Abstract). J Am Soc Nephrol 2015;(Suppl.):26:B1
-
(2015)
J Am Soc Nephrol
, vol.26
, pp. B1
-
-
Wanner, C.L.J.1
Fitchett, D.H.2
Inzucchi, S.E.3
-
108
-
-
84938750467
-
Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice
-
Pathak V, Vasu S, Gault VA, Flatt PR, Irwin N. Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice. Diabetologia 2015;58: 2144-2153
-
(2015)
Diabetologia
, vol.58
, pp. 2144-2153
-
-
Pathak, V.1
Vasu, S.2
Gault, V.A.3
Flatt, P.R.4
Irwin, N.5
|