Development of a Simple Sequential Organ Failure Assessment Score for Risk Assessment of Emergency Department Patients With Sepsis

Journal of Intensive Care Medicine

Volumn 35, Issue 3, 2020, Pages 270-278

  Guirgis, Faheem W ^a   Puskarich, Michael A ^b   Smotherman, Carmen ^a   Sterling, Sarah A ^b   Gautam, Shiva ^a   Moore, Frederick A ^a   Jones, Alan E ^b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

infection; organ dysfunction; sepsis; septic shock

Indexed keywords

HYPERTENSIVE AGENT;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; ARTIFICIAL VENTILATION; CLINICAL ASSESSMENT; EMERGENCY WARD; FEMALE; HOSPITAL MORTALITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; QUICK SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEPSIS; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; HOSPITAL EMERGENCY SERVICE; INTENSIVE CARE UNIT; MORTALITY; ORGAN DYSFUNCTION SCORE; PREDICTIVE VALUE; PROCEDURES; PROGNOSIS; REPRODUCIBILITY;

ADULT; AGED; AREA UNDER CURVE; EMERGENCY SERVICE, HOSPITAL; FEMALE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; ORGAN DYSFUNCTION SCORES; PREDICTIVE VALUE OF TESTS; PROGNOSIS; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEPSIS;

EID: 85041352578     PISSN: 08850666     EISSN: 15251489     Source Type: Journal    
DOI: 10.1177/0885066617741284     Document Type: Article

References (27)

1. Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801–810. doi:10.1001/jama.2016.0287.
2. Boomer JS, To K, Chang KC, et al. Immunosuppression in patients who die of sepsis and multiple organ failure. JAMA. 2011;306(23):2594–2605. doi:10.1001/jama.2011.1829.
3. Walton AH, Muenzer JT, Rasche D, et al. Reactivation of multiple viruses in patients with sepsis. PLoS One. 2014;9(2):e98819. doi:10.1371/journal.pone.0098819.
4. Hotchkiss RS, Monneret G, Payen D. Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy. Nat Rev Immunol. 2013;13(12):862–874. doi:10.1038/nri3552.
5. Gentile LF, Cuenca AG, Efron PA, et al. Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care. J Trauma Acute Care Surg. 2012;72(6):1491–1501. doi:10.1097/TA.0b013e318256e000.
6. Jones AE, Trzeciak S, Kline JA. The Sequential Organ Failure Assessment score for predicting outcome in patients with severe sepsis and evidence of hypoperfusion at the time of emergency department presentation. Crit Care Med. 2009;37(5):1649–1654. doi:10.1097/CCM.0b013e31819def97.
7. Vosylius S, Sipylaite J, Ivaskevicius J. Sequential organ failure assessment score as the determinant of outcome for patients with severe sepsis. Croat Med J. 2004;45(6):715–720.
8. Michalopoulos A, Falagas ME, Karatza DC, et al. Epidemiologic, clinical characteristics, and risk factors for adverse outcome in multiresistant gram-negative primary bacteremia of critically ill patients. Am J Infect Control. 2011;39(5):396–400. doi:10.1016/j.ajic.2010.06.017.
9. Vincent JL, de Mendonca A, Cantraine F, et al. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on “sepsis-related problems” of the European Society of Intensive Care Medicine. Crit Care Med. 1998;26(11):1793–1800.
10. Sterling SA, Puskarich MA, Summers RL, Jones AE. The effect of early quantitative resuscitation on organ function in survivors of septic shock. J Crit Care. 2014;30(2):261–263. doi:10.1016/j.jcrc.2014.10.029.
11. Guirgis FW, Brakenridge S, Sutchu S, et al. The long-term burden of severe sepsis and septic shock: sepsis recidivism and organ dysfunction. J Trauma Acute Care Surg. 2016;81(3):525–532. doi:10.1097/TA.0000000000001135.
12. Seymour CW, Liu VX, Iwashyna TJ, et al. Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):762–774. doi:10.1001/jama.2016.0288.
13. Churpek MM, Snyder A, Han X, et al. qSOFA, SIRS, and early warning scores for detecting clinical deterioration in infected patients outside the ICU. Am J Respir Crit Care Med. 2017;195(7):906–911. doi:10.1164/rccm.201604-0854OC.
14. Marshall JC. Sepsis-3: what is the meaning of a definition? Crit Care Med. 2016;44(8):1459–1460. doi:10.1097/CCM.0000000000001983.
15. Simpson SQ. New sepsis criteria: a change we should not make. Chest. 2016;149(5):1117–1118. doi:10.1016/j.chest.2016.02.653.
16. Dellinger RP, Levy MM, Carlet JM, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock. 2008. Intensive Care Med. 2008;36(1);17–60. doi:10.1097/01.CCM.0000298158.12101.41.
17. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001;29(7):1303–1310.
18. Sharabiani MT, Aylin P, Bottle A. Systematic review of comorbidity indices for administrative data. Med Care. 2012;50(12):1109–1118. doi:10.1097/MLR.0b013e31825f64d0.
19. Li P, Kim MM, Doshi JA. Comparison of the performance of the CMS Hierarchical Condition Category (CMS-HCC) risk adjuster with the Charlson and Elixhauser comorbidity measures in predicting mortality. BMC Health Serv Res. 2010;10:245. doi:10.1186/1472-6963-10-245.
20. Grissom CK, Brown SM, Kuttler KG, et al. A modified sequential organ failure assessment score for critical care triage. Disaster Med Public Health Prep. 2010;4(4):277–284. doi:10.1001/dmp.2010.40.
21. Reith FCM, Van den Brande R, Synnot A, Gruen R, Maas AIR. The reliability of the Glasgow Coma Scale: a systematic review. Intensive Care Med. 2016;42(1):3–15. doi:10.1007/s00134-015-4124-3.
22. Arnold RC, Sherwin R, Shapiro NI, et al. Multicenter observational study of the development of progressive organ dysfunction and therapeutic interventions in normotensive sepsis patients in the emergency department. Acad Emerg Med. 2013;20(5):433–440. doi:10.1111/acem.12137; 10.1111/acem.12137.
23. Shapiro NI, Wolfe RE, Moore RB, Smith E, Burdick E, Bates DW. Mortality in Emergency Department Sepsis (MEDS) score: a prospectively derived and validated clinical prediction rule. Crit Care Med. 2003;31(3):670–675. doi:10.1097/01.CCM.0000054867.01688.D1.
24. Puskarich MA, Nandi U, Long BG, Jones AE. Association between persistent tachycardia and tachypnea and in-hospital mortality among non-hypotensive emergency department patients admitted to the hospital. Clin Exp Emerg Med. 2017;4(1):2–9. doi:10.15441/ceem.16.144.
25. Forward E, Konecny P, Burston J, Adhikari S, Doolan H, Jensen T. Predictive validity of the qSOFA criteria for sepsis in non-ICU inpatients. Intensive Care Med. 2017;46(6):945–946. doi:10.1007/s00134-017-4776-2.
26. Henning DJ, Puskarich MA, Self WH, et al. An emergency department validation of the SEP-3 sepsis and septic shock definitions and comparison with 1992 consensus definitions. Ann Emerg Med. 2017;70(4):544–552.e5. doi:10.1016/j.annemergmed.2017.01.008.
27. Donnelly JP, Safford MM, Shapiro NI, Baddley JW, Wang HE. Application of the third international consensus definitions for sepsis (Sepsis-3) classification: a retrospective population-based cohort study. Lancet Infect Dis. 2017;17(6):661–670. doi:10.1016/S1473-3099(17)30117-2.