Quick sepsis-related organ failure assessment, systemic inflammatory response syndrome, and early warning scores for detecting clinical deterioration in infected patients outside theintensive care unit

American Journal of Respiratory and Critical Care Medicine

Volumn 195, Issue 7, 2017, Pages 906-911

  Churpek, Matthew M ^a,b   Snyder, Ashley ^a   Han, Xuan ^a   Sokol, Sarah ^c   Pettit, Natasha ^c   Howell, Michael D ^a,b   Edelson, Dana P ^a,b  

^a UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^b Center for Healthcare Delivery Science and Innovation   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Early warning scores; Organ dysfunction Scores; QSOFA; Sepsis; Systemic inflammatory response syndrome

Indexed keywords

ANTIBIOTIC AGENT;

ACCURACY; ADULT; ADVERSE OUTCOME; AGED; ARTICLE; DEATH; EMERGENCY WARD; FEMALE; GENERAL CONDITION DETERIORATION; HIGH RISK PATIENT; HOSPITAL MORTALITY; HUMAN; INFECTION; INTENSIVE CARE UNIT; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MODIFIED EARLY WARNING SCORE; NATIONAL EARLY WARNING SCORE; ORGAN DYSFUNCTION SCORE; OUTCOME ASSESSMENT; PATIENT TRANSPORT; PREDICTION; PRIORITY JOURNAL; QUICK SEPSIS RELATED ORGAN FAILURE ASSESSMENT; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; WARD; COMPLICATION; HOSPITAL EMERGENCY SERVICE; HOSPITALIZATION; MIDDLE AGED; RECEIVER OPERATING CHARACTERISTIC; REPRODUCIBILITY; RISK ASSESSMENT; SEPSIS;

EMERGENCY SERVICE, HOSPITAL; FEMALE; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; ORGAN DYSFUNCTION SCORES; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 85017407164     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201604-0854OC     Document Type: Article

References (26)

1. Liu V, Escobar GJ, Greene JD, Soule J, Whippy A, Angus DC, Iwashyna TJ. Hospital deaths in patients with sepsis from 2 independent cohorts. JAMA 2014;312:90-92.
2. Lagu T, Rothberg MB, Shieh MS, Pekow PS, Steingrub JS, Lindenauer PK. Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007. Crit Care Med 2012;40:754-761.
3. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992;101:1644-1655.
4. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G; SCCM/ESICM/ACCP/ATS/SIS. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31:1250-1256.
5. Vincent JL. Dear SIRS, I'm sorry to say that I don't like you. . . . Crit Care Med 1997;25:372-374.
6. Churpek MM, Zadravecz FJ, Winslow C, Howell MD, Edelson DP. Incidence and prognostic value of the systemic inflammatory response syndrome and organ dysfunctions in ward patients. Am J Respir Crit Care Med 2015;192:958-964.
7. Sprung CL, Sakr Y, Vincent JL, Le Gall JR, Reinhart K, Ranieri VM, Gerlach H, Fielden J, Groba CB, Payen D. An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence In Acutely Ill Patients (SOAP) study. Intensive Care Med 2006;32:421-427.
8. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016;315:801-810.
9. Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD, Scherag A, Rubenfeld G, Kahn JM, Shankar-Hari M, Singer M, et al. Assessment of clinical criteria for sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016;315:762-774.
10. Levy MM, Rhodes A, Phillips GS, Townsend SR, Schorr CA, Beale R, Osborn T, Lemeshow S, Chiche JD, Artigas A, et al. Surviving sepsis campaign: Association between performance metrics and outcomes in a 7. 5-year study. Crit Care Med 2015;43:3-12.
11. Simpson SQ. New sepsis criteria: A change we should not make. Chest 2016;149:1117-1118.
12. Subbe CP, Kruger M, Rutherford P, Gemmel L. Validation of a modified early warning score in medical admissions. QJM 2001;94:521-526.
13. Smith GB, Prytherch DR, Meredith P, Schmidt PE, Featherstone PI. The ability of the National Early Warning Score (NEWS) to discriminate patients at risk of early cardiac arrest, unanticipated intensive care unit admission, and death. Resuscitation 2013;84:465-470.
14. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, et al. ; Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med 2013;41:580-637.
15. Angus DC, Linde-ZwirbleWT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001;29:1303-1310.
16. ChurpekMM, Yuen TC, Winslow C, Robicsek AA, Meltzer DO, Gibbons RD, Edelson DP. Multicenter development and validation of a risk stratification tool for ward patients. Am J Respir Crit Care Med 2014; 190:649-655.
17. Knaus WA, Wagner DP, Draper EA, Zimmerman JE, Bergner M, Bastos PG, Sirio CA, Murphy DJ, Lotring T, Damiano A, et al. The APACHE III prognostic system: Risk prediction of hospital mortality for critically ill hospitalized adults. Chest 1991;100: 1619-1636.
18. Royal College of Physicians. National early warning score (NEWS): Standardising the assessment of acute illness severity in the NHS. London: Royal College of Physicians; 2012.
19. Jones DA, DeVita MA, Bellomo R. Rapid-response teams. N Engl J Med 2011;365:139-146.
20. Smith ME, Chiovaro JC, O'Neil M, Kansagara D, Quinoñes AR, Freeman M, Motu'apuaka ML, Slatore CG. Early warning system scores for clinical deterioration in hospitalized patients: A systematic review. Ann Am Thorac Soc 2014;11:1454-1465.
21. Moskowitz A, Andersen LW, Cocchi M, Donnino MW. The misapplication of severity-of-illness scores toward clinical decision making. Am J Respir Crit Care Med 2016;194:256-258.
22. Prytherch DR, Smith GB, Schmidt P, Featherstone PI, Stewart K, Knight D, Higgins B. Calculating early warning scores: A classroom comparison of pen and paper and hand-held computer methods. Resuscitation 2006;70:173-178.
23. Patel AR, Zadravecz FJ, Young RS, Williams MV, Churpek MM, Edelson DP. The value of clinical judgment in the detection of clinical deterioration. JAMA Intern Med 2015;175:456-458.
24. Fullerton JN, Price CL, Silvey NE, Brace SJ, Perkins GD. Is the Modified Early Warning Score (MEWS) superior to clinician judgement in detecting critical illness in the pre-hospital environment Resuscitation 2012;83:557-562.
25. Kang MA, Churpek MM, Zadravecz FJ, Adhikari R, Twu NM, Edelson DP. Real-time risk prediction on the wards: A feasibility study. Crit Care Med 2016;44:1468-1473.
26. Churpek MM, Yuen TC, Edelson DP. Risk stratification of hospitalized patients on the wards. Chest 2013;143:1758-1765.