Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell

Cell

Volumn 172, Issue 1-2, 2018, Pages 191-204.e10

  Hoggatt, Jonathan ^a,b,c   Singh, Pratibha ^d   Tate, Tiffany A ^b,c   Chou, Bin Kuan ^a,b   Datari, Shruti R ^a,b   Fukuda, Seiji ^d,h   Liu, Liqiong ^d   Kharchenko, Peter V ^b,e   Schajnovitz, Amir ^b,c,f   Baryawno, Ninib ^b,c,f   Mercier, Francois E ^b,c,f   Boyer, Joseph ^g   Gardner, Jason ^g,i   Morrow, Dwight M ^g   Scadden, David T ^b,c,f   Pelus, Louis M ^d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

^c Harvard University   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^g GLAXOSMITHKLINE   (United States)

^h SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

ⁱ Magenta Therapeutics   (United States)

Author keywords

AMD3100; bone marrow transplantation; CXCR2; CXCR4; granulocyte colony stimulating factor; hematopoiesis; hematopoietic stem cell mobilization; MMP 9; neutrophils; stem cell trafficking

Indexed keywords

CHEMOKINE RECEPTOR AGONIST; GELATINASE B; GRANULOCYTE COLONY STIMULATING FACTOR; GRO BETA; PLERIXAFOR; UNCLASSIFIED DRUG; CXCL2 CHEMOKINE; HETEROCYCLIC COMPOUND; PLERIXAFOR OCTAHYDROCHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIMIT OF QUANTITATION; MALE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; SIGNAL TRANSDUCTION; STEM CELL MOBILIZATION; ADULT; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; DBA MOUSE; DRUG EFFECT; GENETICS; HEMATOPOIETIC STEM CELL; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; PROCEDURES;

ADULT; ANIMALS; CHEMOKINE CXCL2; FEMALE; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HETEROCYCLIC COMPOUNDS; HUMANS; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, INBRED ICR; POLYMORPHISM, GENETIC;

EID: 85041113078     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.11.003     Document Type: Article

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