The chemokine receptor CXCR4 is expressed within the mast cell lineage and its ligand stromal cell-derived factor-1α acts as a mast cell chemotaxin

European Journal of Immunology

Volumn 30, Issue 12, 2000, Pages 3614-3622

  Juremalm, Mikael ^a   Hjertson, Malin ^b   Olsson, Niclas ^a   Harvima, Ilkka ^b   Nilsson, Kenneth ^b   Nilsson, Gunnar ^a,c  

^a UPPSALA UNIVERSITY   (Sweden)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Chemotaxis; CXCR4; Inflammation; Mast cell

Indexed keywords

CHEMOATTRACTANT; CHEMOKINE RECEPTOR CXCR4; CHEMOTAXIN; PERTUSSIS TOXIN; PROTEIN G; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL LINEAGE; CELL MIGRATION; ENZYME ANALYSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MAST CELL; PRIORITY JOURNAL; STEM CELL; UMBILICAL CORD BLOOD;

CALCIUM; CELL MOVEMENT; CHEMOKINES, CXC; CHEMOTACTIC FACTORS; HUMANS; MAST CELLS; ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTORS, CXCR4; STEM CELL FACTOR; STEM CELLS;

EID: 0034536801     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200012)30:12<3614::AID-IMMU3614>3.0.CO;2-B     Document Type: Article

References (49)

1. + bone marrow progenitor cells
2. Origin of human mast cells: Development from transplanted hematopoietic stem cells after allogeneic bone marrow transplantation
3. +/Fc epsilon RI-cell population
4. Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13)
5. -, colony-forming cell
6. The c-kit receptor ligand functions as a mast cell chemoattractant
7. Stem cell factor is a chemotactic factor for human mast cells
8. Mast cell chemotactic activity of RANTES
9. Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/Interleukin-8RB
10. Expression and functional activity of the IL-8 receptor type CXCR1 CXCR2 on human mast cells
11. Tryptasechymase double-positive human mast cells express the eotaxin receptor CCR3 and are attracted by CCR3-binding chemokines
12. Transforming growth factor-beta 1 mediates mast cell chemotaxis
13. Human mast cell migration in response to members of the transforming growth factor-β family
14. C3a and C5a stimulate chemotaxis of human mast cells
15. C3a and C5a are chemotaxins for human mast cells act through distinct receptors via a pertussis toxin-sensitive signal transduction pathway
16. Serum amyloid A induces chemotaxis of human mast cells by activating a pertussis toxin-sensitive signal transduction pathway
17. Demonstration that platelet-activating factor is capable of activating mast cells and inducing a chemotactic response
18. Chemokines-chemotactic cytokines that mediate inflammation
19. Chemokines and leukocyte traffic
20. Chemokines: A new classification system and their role in immunity
21. CC chemokines in allergic inflammation
22. Chemokine receptor specific for IP10 and Mig: Structure, function and expression in activated T-lymphocytes
23. B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5
24. Molecular cloning and structure of a pre-B-cell growth-stimulating factor
25. A highly efficacious lymphocyte chemoattractant stromal cell-derived factor 1 (SDF-1)
26. The alphachemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion
27. + progenitor cells: CXC chemokine receptor 4 and CC chemokine receptor 5 expression and infection by HIV
28. Selective transendothelial migration of hematopoietic progenitor cells: A role in homing of progenitor cells
29. Cloning of a human seven-transmembrane domain receptor, LESTR that is highly expressed in leukocytes
30. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
31. The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4
32. Human immunodeficiency virus-1 entry into purified blood dendritic cells through CC and CXC chemokine coreceptors
33. + hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1
34. Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors
35. Establishment of an immature mast cell line from a patient with mast cell leukemia
36. Stem cell factor-dependent human cord blood derived mast cells express α- and β-tryptase, heparin and chondroitin sulphate
37. Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis
38. B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement
39. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes
40. T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro
41. Interleukin-4 inhibits the expression of Kit and tryptase during stem cell factor-dependent development of human mast cells from fetal liver cells
42. Effect of recombinant human IL-4 on tryptase, chymase, and Fc epsilon receptor type I expression in recombinant human stem cell factor-dependent fetal liver-derived human mast cells
43. Induction of the high-affinity IgE receptor (Fc epsilon RI) on human mast cells by IL-4
44. + progenitors to peripheral blood
45. Phenotypic characterization of the human mast cell line HMC-1
46. + indicators with greatly improved fluorescence properties
47. Leukocyte locomotion and chemotaxis
48. CD4-independent infection by HIV-2 is mediated by fusin/CXCR4
49. Separation and partial characterization of proteinases with substrate specificity for basic amino acids from human MOLT-4 T lymphocytes: Identification of those inhibited by variable-loop-V3 peptides of HIV-1 (human immunodeficiency virus-1) envelope glycoprotein