-
1
-
-
84860210262
-
Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease
-
Swerdlow, R.H., Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease. Antioxid Redox Signal 16 (2012), 1434–1455.
-
(2012)
Antioxid Redox Signal
, vol.16
, pp. 1434-1455
-
-
Swerdlow, R.H.1
-
2
-
-
0029444246
-
Age-related changes in brain: II. Positron emission tomography of frontal and temporal lobe glucose metabolism in normal subjects
-
De Santi, S., de Leon, M.J., Convit, A., Tarshish, C., Rusinek, H., Tsui, W.H., et al. Age-related changes in brain: II. Positron emission tomography of frontal and temporal lobe glucose metabolism in normal subjects. Psychiatr Q 66 (1995), 357–370.
-
(1995)
Psychiatr Q
, vol.66
, pp. 357-370
-
-
De Santi, S.1
de Leon, M.J.2
Convit, A.3
Tarshish, C.4
Rusinek, H.5
Tsui, W.H.6
-
3
-
-
84903362456
-
Brain glucose and acetoacetate metabolism: a comparison of young and older adults
-
Nugent, S., Tremblay, S., Chen, K.W., Ayutyanont, N., Roontiva, A., Castellano, C.A., et al. Brain glucose and acetoacetate metabolism: a comparison of young and older adults. Neurobiol Aging 35 (2014), 1386–1395.
-
(2014)
Neurobiol Aging
, vol.35
, pp. 1386-1395
-
-
Nugent, S.1
Tremblay, S.2
Chen, K.W.3
Ayutyanont, N.4
Roontiva, A.5
Castellano, C.A.6
-
4
-
-
0019270679
-
Positron emission tomography in the study of aging and senile dementia
-
Ferris, S.H., de Leon, M.J., Wolf, A.P., Farkas, T., Christman, D.R., Reisberg, B., et al. Positron emission tomography in the study of aging and senile dementia. Neurobiol Aging 1 (1980), 127–131.
-
(1980)
Neurobiol Aging
, vol.1
, pp. 127-131
-
-
Ferris, S.H.1
de Leon, M.J.2
Wolf, A.P.3
Farkas, T.4
Christman, D.R.5
Reisberg, B.6
-
5
-
-
0020518539
-
Alzheimer's disease: focal cortical changes shown by positron emission tomography
-
Foster, N.L., Chase, T.N., Fedio, P., Patronas, N.J., Brooks, R.A., Di Chiro, G., Alzheimer's disease: focal cortical changes shown by positron emission tomography. Neurology 33 (1983), 961–965.
-
(1983)
Neurology
, vol.33
, pp. 961-965
-
-
Foster, N.L.1
Chase, T.N.2
Fedio, P.3
Patronas, N.J.4
Brooks, R.A.5
Di Chiro, G.6
-
6
-
-
0029970342
-
Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E
-
Reiman, E.M., Caselli, R.J., Yun, L.S., Chen, K., Bandy, D., Minoshima, S., et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. N Engl J Med 334 (1996), 752–758.
-
(1996)
N Engl J Med
, vol.334
, pp. 752-758
-
-
Reiman, E.M.1
Caselli, R.J.2
Yun, L.S.3
Chen, K.4
Bandy, D.5
Minoshima, S.6
-
7
-
-
0028950856
-
Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease
-
Small, G.W., Mazziotta, J.C., Collins, M.T., Baxter, L.R., Phelps, M.E., Mandelkern, M.A., et al. Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease. JAMA 273 (1995), 942–947.
-
(1995)
JAMA
, vol.273
, pp. 942-947
-
-
Small, G.W.1
Mazziotta, J.C.2
Collins, M.T.3
Baxter, L.R.4
Phelps, M.E.5
Mandelkern, M.A.6
-
8
-
-
37649001373
-
Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism
-
Mosconi, L., Brys, M., Switalski, R., Mistur, R., Glodzik, L., Pirraglia, E., et al. Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism. Proc Natl Acad Sci U S A 104 (2007), 19067–19072.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19067-19072
-
-
Mosconi, L.1
Brys, M.2
Switalski, R.3
Mistur, R.4
Glodzik, L.5
Pirraglia, E.6
-
9
-
-
0027959878
-
Brain glucose metabolism in Alzheimer's disease
-
Swerdlow, R., Marcus, D.L., Landman, J., Kooby, D., Frey, W. 2nd, Freedman, M.L., Brain glucose metabolism in Alzheimer's disease. Am J Med Sci 308 (1994), 141–144.
-
(1994)
Am J Med Sci
, vol.308
, pp. 141-144
-
-
Swerdlow, R.1
Marcus, D.L.2
Landman, J.3
Kooby, D.4
Frey, W.5
Freedman, M.L.6
-
10
-
-
84897409736
-
Bioenergetic medicine
-
Swerdlow, R.H., Bioenergetic medicine. Br J Pharmacol 171 (2014), 1854–1869.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 1854-1869
-
-
Swerdlow, R.H.1
-
11
-
-
70350731779
-
Ketogenic diets: an update for child neurologists
-
Kossoff, E.H., Zupec-Kania, B.A., Rho, J.M., Ketogenic diets: an update for child neurologists. J Child Neurol 24 (2009), 979–988.
-
(2009)
J Child Neurol
, vol.24
, pp. 979-988
-
-
Kossoff, E.H.1
Zupec-Kania, B.A.2
Rho, J.M.3
-
12
-
-
0014139879
-
Brain metabolism during fasting
-
Owen, O.E., Morgan, A.P., Kemp, H.G., Sullivan, J.M., Herrera, M.G., Cahill, G.F. Jr., Brain metabolism during fasting. J Clin Invest 46 (1967), 1589–1595.
-
(1967)
J Clin Invest
, vol.46
, pp. 1589-1595
-
-
Owen, O.E.1
Morgan, A.P.2
Kemp, H.G.3
Sullivan, J.M.4
Herrera, M.G.5
Cahill, G.F.6
-
13
-
-
0023470792
-
Capacity for substrate utilization in oxidative metabolism by neurons, astrocytes, and oligodendrocytes from developing brain in primary culture
-
Edmond, J., Robbins, R.A., Bergstrom, J.D., Cole, R.A., de Vellis, J., Capacity for substrate utilization in oxidative metabolism by neurons, astrocytes, and oligodendrocytes from developing brain in primary culture. J Neurosci Res 18 (1987), 551–561.
-
(1987)
J Neurosci Res
, vol.18
, pp. 551-561
-
-
Edmond, J.1
Robbins, R.A.2
Bergstrom, J.D.3
Cole, R.A.4
de Vellis, J.5
-
14
-
-
0028813537
-
Blood-brain barrier permeability of glucose and ketone bodies during short-term starvation in humans
-
Hasselbalch, S.G., Knudsen, G.M., Jakobsen, J., Hageman, L.P., Holm, S., Paulson, O.B., Blood-brain barrier permeability of glucose and ketone bodies during short-term starvation in humans. Am J Physiol 268 (1995), E1161–E1166.
-
(1995)
Am J Physiol
, vol.268
, pp. E1161-E1166
-
-
Hasselbalch, S.G.1
Knudsen, G.M.2
Jakobsen, J.3
Hageman, L.P.4
Holm, S.5
Paulson, O.B.6
-
15
-
-
84984623335
-
Can ketones help rescue brain fuel supply in later life? Implications for cognitive health during aging and the treatment of Alzheimer's disease
-
Cunnane, S.C., Courchesne-Loyer, A., Vandenberghe, C., St-Pierre, V., Fortier, M., Hennebelle, M., et al. Can ketones help rescue brain fuel supply in later life? Implications for cognitive health during aging and the treatment of Alzheimer's disease. Front Mol Neurosci, 9, 2016, 53.
-
(2016)
Front Mol Neurosci
, vol.9
, pp. 53
-
-
Cunnane, S.C.1
Courchesne-Loyer, A.2
Vandenberghe, C.3
St-Pierre, V.4
Fortier, M.5
Hennebelle, M.6
-
16
-
-
84919917084
-
Lower brain 18F-fluorodeoxyglucose uptake but normal 11C-acetoacetate metabolism in mild Alzheimer's disease dementia
-
Castellano, C.A., Nugent, S., Paquet, N., Tremblay, S., Bocti, C., Lacombe, G., et al. Lower brain 18F-fluorodeoxyglucose uptake but normal 11C-acetoacetate metabolism in mild Alzheimer's disease dementia. J Alzheimers Dis 43 (2015), 1343–1353.
-
(2015)
J Alzheimers Dis
, vol.43
, pp. 1343-1353
-
-
Castellano, C.A.1
Nugent, S.2
Paquet, N.3
Tremblay, S.4
Bocti, C.5
Lacombe, G.6
-
17
-
-
74549188639
-
Brain glucose and ketone body metabolism in patients with Alzheimer's disease
-
Swerdlow, R., Marcus, D.M., Landman, J., Harooni, M., Freedman, M.L., Brain glucose and ketone body metabolism in patients with Alzheimer's disease. Clin Res, 37, 1989, 461A.
-
(1989)
Clin Res
, vol.37
, pp. 461A
-
-
Swerdlow, R.1
Marcus, D.M.2
Landman, J.3
Harooni, M.4
Freedman, M.L.5
-
18
-
-
59049104610
-
Caloric restriction improves memory in elderly humans
-
Witte, A.V., Fobker, M., Gellner, R., Knecht, S., Floel, A., Caloric restriction improves memory in elderly humans. Proc Natl Acad Sci U S A 106 (2009), 1255–1260.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1255-1260
-
-
Witte, A.V.1
Fobker, M.2
Gellner, R.3
Knecht, S.4
Floel, A.5
-
19
-
-
82755194976
-
Dietary ketosis enhances memory in mild cognitive impairment
-
Krikorian, R., Shidler, M.D., Dangelo, K., Couch, S.C., Benoit, S.C., Clegg, D.J., Dietary ketosis enhances memory in mild cognitive impairment. Neurobiol Aging 33 (2012), 425.e19–425.e27.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 425.e19-425.e27
-
-
Krikorian, R.1
Shidler, M.D.2
Dangelo, K.3
Couch, S.C.4
Benoit, S.C.5
Clegg, D.J.6
-
20
-
-
84983802988
-
Effect of a ketogenic meal on cognitive function in elderly adults: potential for cognitive enhancement
-
Ota, M., Matsuo, J., Ishida, I., Hattori, K., Teraishi, T., Tonouchi, H., et al. Effect of a ketogenic meal on cognitive function in elderly adults: potential for cognitive enhancement. Psychopharmacology (Berl) 233 (2016), 3797–3802.
-
(2016)
Psychopharmacology (Berl)
, vol.233
, pp. 3797-3802
-
-
Ota, M.1
Matsuo, J.2
Ishida, I.3
Hattori, K.4
Teraishi, T.5
Tonouchi, H.6
-
21
-
-
1242338801
-
Effects of beta-hydroxybutyrate on cognition in memory-impaired adults
-
Reger, M.A., Henderson, S.T., Hale, C., Cholerton, B., Baker, L.D., Watson, G.S., et al. Effects of beta-hydroxybutyrate on cognition in memory-impaired adults. Neurobiol Aging 25 (2004), 311–314.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 311-314
-
-
Reger, M.A.1
Henderson, S.T.2
Hale, C.3
Cholerton, B.4
Baker, L.D.5
Watson, G.S.6
-
22
-
-
69449085062
-
Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial
-
Henderson, S.T., Vogel, J.L., Barr, L.J., Garvin, F., Jones, J.J., Costantini, L.C., Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial. Nutr Metab (Lond), 6, 2009, 31.
-
(2009)
Nutr Metab (Lond)
, vol.6
, pp. 31
-
-
Henderson, S.T.1
Vogel, J.L.2
Barr, L.J.3
Garvin, F.4
Jones, J.J.5
Costantini, L.C.6
-
23
-
-
79956142378
-
The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
McKhann, G.M., Knopman, D.S., Chertkow, H., Hyman, B.T., Jack, C.R. Jr., Kawas, C.H., et al. The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7 (2011), 263–269.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 263-269
-
-
McKhann, G.M.1
Knopman, D.S.2
Chertkow, H.3
Hyman, B.T.4
Jack, C.R.5
Kawas, C.H.6
-
24
-
-
0025062451
-
A new predictive equation for resting energy expenditure in healthy individuals
-
Mifflin, M.D., St Jeor, S.T., Hill, L.A., Scott, B.J., Daugherty, S.A., Koh, Y.O., A new predictive equation for resting energy expenditure in healthy individuals. Am J Clin Nutr 51 (1990), 241–247.
-
(1990)
Am J Clin Nutr
, vol.51
, pp. 241-247
-
-
Mifflin, M.D.1
St Jeor, S.T.2
Hill, L.A.3
Scott, B.J.4
Daugherty, S.A.5
Koh, Y.O.6
-
25
-
-
84962722736
-
Establishing an Adult Epilepsy Diet Center: Experience, efficacy and challenges
-
Cervenka, M.C., Henry, B.J., Felton, E.A., Patton, K., Kossoff, E.H., Establishing an Adult Epilepsy Diet Center: Experience, efficacy and challenges. Epilepsy Behav 58 (2016), 61–68.
-
(2016)
Epilepsy Behav
, vol.58
, pp. 61-68
-
-
Cervenka, M.C.1
Henry, B.J.2
Felton, E.A.3
Patton, K.4
Kossoff, E.H.5
-
26
-
-
57549095804
-
Ketogenic diet treatment in adults with refractory epilepsy: a prospective pilot study
-
Mosek, A., Natour, H., Neufeld, M.Y., Shiff, Y., Vaisman, N., Ketogenic diet treatment in adults with refractory epilepsy: a prospective pilot study. Seizure 18 (2009), 30–33.
-
(2009)
Seizure
, vol.18
, pp. 30-33
-
-
Mosek, A.1
Natour, H.2
Neufeld, M.Y.3
Shiff, Y.4
Vaisman, N.5
-
27
-
-
84941342359
-
Measuring the caregiver burden of caring for community-residing people with Alzheimer's disease
-
Yu, H., Wang, X., He, R., Liang, R., Zhou, L., Measuring the caregiver burden of caring for community-residing people with Alzheimer's disease. PLoS One, 10, 2015, e0132168.
-
(2015)
PLoS One
, vol.10
, pp. e0132168
-
-
Yu, H.1
Wang, X.2
He, R.3
Liang, R.4
Zhou, L.5
-
28
-
-
65549152475
-
A randomized trial of classical and medium-chain triglyceride ketogenic diets in the treatment of childhood epilepsy
-
Neal, E.G., Chaffe, H., Schwartz, R.H., Lawson, M.S., Edwards, N., Fitzsimmons, G., et al. A randomized trial of classical and medium-chain triglyceride ketogenic diets in the treatment of childhood epilepsy. Epilepsia 50 (2009), 1109–1117.
-
(2009)
Epilepsia
, vol.50
, pp. 1109-1117
-
-
Neal, E.G.1
Chaffe, H.2
Schwartz, R.H.3
Lawson, M.S.4
Edwards, N.5
Fitzsimmons, G.6
-
29
-
-
84930088691
-
Caloric restriction increases ketone bodies metabolism and preserves blood flow in aging brain
-
Lin, A.L., Zhang, W., Gao, X., Watts, L., Caloric restriction increases ketone bodies metabolism and preserves blood flow in aging brain. Neurobiol Aging 36 (2015), 2296–2303.
-
(2015)
Neurobiol Aging
, vol.36
, pp. 2296-2303
-
-
Lin, A.L.1
Zhang, W.2
Gao, X.3
Watts, L.4
-
30
-
-
84922709891
-
A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease
-
Newport, M.T., VanItallie, T.B., Kashiwaya, Y., King, M.T., Veech, R.L., A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease. Alzheimers Dement 11 (2015), 99–103.
-
(2015)
Alzheimers Dement
, vol.11
, pp. 99-103
-
-
Newport, M.T.1
VanItallie, T.B.2
Kashiwaya, Y.3
King, M.T.4
Veech, R.L.5
-
31
-
-
85013177882
-
Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics
-
Puchalska, P., Crawford, P.A., Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics. Cell Metab 25 (2017), 262–284.
-
(2017)
Cell Metab
, vol.25
, pp. 262-284
-
-
Puchalska, P.1
Crawford, P.A.2
-
32
-
-
84922566816
-
Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure
-
Selfridge, J.E., Wilkins, H.M., Lezi, E., Carl, S.M., Koppel, S., Funk, E., et al. Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure. J Bioenerg Biomembr 47 (2015), 1–11.
-
(2015)
J Bioenerg Biomembr
, vol.47
, pp. 1-11
-
-
Selfridge, J.E.1
Wilkins, H.M.2
Lezi, E.3
Carl, S.M.4
Koppel, S.5
Funk, E.6
-
33
-
-
84936846247
-
Ketogenic diet exhibits anti-inflammatory properties
-
Dupuis, N., Curatolo, N., Benoist, J.F., Auvin, S., Ketogenic diet exhibits anti-inflammatory properties. Epilepsia 56 (2015), e95–e98.
-
(2015)
Epilepsia
, vol.56
, pp. e95-e98
-
-
Dupuis, N.1
Curatolo, N.2
Benoist, J.F.3
Auvin, S.4
-
34
-
-
79952570329
-
The ketogenic diet inhibits the mammalian target of rapamycin (mTOR) pathway
-
McDaniel, S.S., Rensing, N.R., Thio, L.L., Yamada, K.A., Wong, M., The ketogenic diet inhibits the mammalian target of rapamycin (mTOR) pathway. Epilepsia 52 (2011), e7–e11.
-
(2011)
Epilepsia
, vol.52
, pp. e7-e11
-
-
McDaniel, S.S.1
Rensing, N.R.2
Thio, L.L.3
Yamada, K.A.4
Wong, M.5
-
35
-
-
33746848935
-
Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet
-
Bough, K.J., Wetherington, J., Hassel, B., Pare, J.F., Gawryluk, J.W., Greene, J.G., et al. Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet. Ann Neurol 60 (2006), 223–235.
-
(2006)
Ann Neurol
, vol.60
, pp. 223-235
-
-
Bough, K.J.1
Wetherington, J.2
Hassel, B.3
Pare, J.F.4
Gawryluk, J.W.5
Greene, J.G.6
-
36
-
-
34248147101
-
The neuropharmacology of the ketogenic diet
-
Hartman, A.L., Gasior, M., Vining, E.P., Rogawski, M.A., The neuropharmacology of the ketogenic diet. Pediatr Neurol 36 (2007), 281–292.
-
(2007)
Pediatr Neurol
, vol.36
, pp. 281-292
-
-
Hartman, A.L.1
Gasior, M.2
Vining, E.P.3
Rogawski, M.A.4
-
37
-
-
4644241829
-
A cDNA microarray analysis of gene expression profiles in rat hippocampus following a ketogenic diet
-
Noh, H.S., Lee, H.P., Kim, D.W., Kang, S.S., Cho, G.J., Rho, J.M., et al. A cDNA microarray analysis of gene expression profiles in rat hippocampus following a ketogenic diet. Brain Res Mol Brain Res 129 (2004), 80–87.
-
(2004)
Brain Res Mol Brain Res
, vol.129
, pp. 80-87
-
-
Noh, H.S.1
Lee, H.P.2
Kim, D.W.3
Kang, S.S.4
Cho, G.J.5
Rho, J.M.6
-
38
-
-
0035346949
-
Is there an astrocyte-neuron ketone body shuttle?
-
Guzman, M., Blazquez, C., Is there an astrocyte-neuron ketone body shuttle?. Trends Endocrinol Metab 12 (2001), 169–173.
-
(2001)
Trends Endocrinol Metab
, vol.12
, pp. 169-173
-
-
Guzman, M.1
Blazquez, C.2
-
39
-
-
84920587151
-
β-hydroxybutyrate: much more than a metabolite
-
Newman, J.C., Verdin, E., β-hydroxybutyrate: much more than a metabolite. Diabetes Res Clin Pract 106 (2014), 173–181.
-
(2014)
Diabetes Res Clin Pract
, vol.106
, pp. 173-181
-
-
Newman, J.C.1
Verdin, E.2
-
40
-
-
84949624063
-
Protein acetylation in metabolism - metabolites and cofactors
-
Menzies, K.J., Zhang, H., Katsyuba, E., Auwerx, J., Protein acetylation in metabolism - metabolites and cofactors. Nat Rev Endocrinol 12 (2016), 43–60.
-
(2016)
Nat Rev Endocrinol
, vol.12
, pp. 43-60
-
-
Menzies, K.J.1
Zhang, H.2
Katsyuba, E.3
Auwerx, J.4
-
41
-
-
84963812301
-
Metabolic regulation of gene expression by histone lysine beta-hydroxybutyrylation
-
Xie, Z., Zhang, D., Chung, D., Tang, Z., Huang, H., Dai, L., et al. Metabolic regulation of gene expression by histone lysine beta-hydroxybutyrylation. Mol Cell 62 (2016), 194–206.
-
(2016)
Mol Cell
, vol.62
, pp. 194-206
-
-
Xie, Z.1
Zhang, D.2
Chung, D.3
Tang, Z.4
Huang, H.5
Dai, L.6
-
42
-
-
1042265019
-
The ketogenic diet; fatty acids, fatty acid-activated receptors and neurological disorders
-
Cullingford, T.E., The ketogenic diet; fatty acids, fatty acid-activated receptors and neurological disorders. Prostaglandins Leukot Essent Fatty Acids 70 (2004), 253–264.
-
(2004)
Prostaglandins Leukot Essent Fatty Acids
, vol.70
, pp. 253-264
-
-
Cullingford, T.E.1
|