Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation

Science

Volumn 359, Issue 6375, 2018, Pages 545-550

  Wild, Rebekka ^a   Kowal, Julia ^a   Eyring, Jillianne ^a   Ngwa, Elsy M ^a   Aebi, Markus ^a   Locher, Kaspar P ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCAN; MEMBRANE PROTEIN; OLIGOSACCHARYLTRANSFERASE; OLIGOSACCHARYLTRANSFERASE 3; OLIGOSACCHARYLTRANSFERASE 4; OLIGOSACCHARYLTRANSFERASE 5; OLIGOSACCHARYLTRANSFERASE 6; OXIDOREDUCTASE; UNCLASSIFIED DRUG; DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE - PROTEIN GLYCOTRANSFERASE; GLYCOSYLTRANSFERASE; MULTIENZYME COMPLEX; SACCHAROMYCES CEREVISIAE PROTEIN; STT3 PROTEIN, S CEREVISIAE;

CATALYSIS; CELL ORGANELLE; CHEMICAL REACTION; COMPLEXITY; EUKARYOTE; MEMBRANE; PEPTIDE; PROTEIN; YEAST;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME GLYCOSYLATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN MODIFICATION; STRUCTURAL HOMOLOGY; THREE DIMENSIONAL IMAGING; CHEMISTRY; CONSERVED SEQUENCE; CRYOELECTRON MICROSCOPY; ENZYME SPECIFICITY; GLYCOSYLATION; ULTRASTRUCTURE;

EUKARYOTA;

CATALYTIC DOMAIN; CONSERVED SEQUENCE; CRYOELECTRON MICROSCOPY; GLYCOSYLATION; HEXOSYLTRANSFERASES; MEMBRANE PROTEINS; MULTIENZYME COMPLEXES; OXIDATION-REDUCTION; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY;

EID: 85040050034     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aar5140     Document Type: Article

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