Unexpected reactivity and mechanism of carboxamide activation in bacterial N-linked protein glycosylation

Nature Communications

Volumn 4, Issue , 2013, Pages

  Lizak, Christian ^a   Gerber, Sabina ^a,c   Michaud, Gaëlle ^b   Schubert, Mario ^a   Fan, Yao Yun ^a   Bucher, Monika ^a   Darbre, Tamis ^b   Aebi, Markus ^a   Reymond, Jean Louis ^b   Locher, Kaspar P ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c GlycoVaxyn AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINOBUTYRIC ACID; AMIDE; ASPARAGINE; BACTERIAL PROTEIN; BASE; GLUTAMINE; HOMOSERINE; HYDROXAMIC ACID; MEMBRANE ENZYME; OLIGOSACCHARYLTRANSFERASE; PEPTIDE DERIVATIVE; PGLB PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID; AMMONIUM COMPOUND; BACTERIUM; BIOCHEMISTRY; ENZYME ACTIVITY; PEPTIDE; PROTEIN;

ANIMAL CELL; ARTICLE; BACTERIUM; BINDING SITE; CHEMICAL REACTION; CONTROLLED STUDY; DEPROTONATION; ESCHERICHIA COLI; IN VITRO STUDY; NONHUMAN; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN GLYCOSYLATION; PROTEIN METHYLATION; PROTEIN SYNTHESIS; PROTON TRANSPORT;

BACTERIA (MICROORGANISMS);

AMIDES; ASPARAGINE; ASPARTIC ACID; BACTERIAL PROTEINS; BINDING SITES; CAMPYLOBACTER JEJUNI; CAMPYLOBACTER LARI; ESCHERICHIA COLI; GENE EXPRESSION; GLUTAMINE; GLYCOSYLATION; HEXOSYLTRANSFERASES; HOMOSERINE; KINETICS; MEMBRANE PROTEINS; MODELS, MOLECULAR; PROTEIN BINDING; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84889264480     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3627     Document Type: Article

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