Particles on the lung surface - physicochemical and hydrodynamic effects

Current Opinion in Colloid and Interface Science

Volumn 36, Issue , 2018, Pages 1-9

  Sosnowski, Tomasz R ^a  

^a WARSAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Adsorption; Lung surfactant; Marangoni effects; Surface tension

Indexed keywords

ADSORPTION; BIOCHEMISTRY; MASS TRANSFER; PHASE INTERFACES; SURFACE ACTIVE AGENTS; SURFACE TENSION;

DOSE-DEPENDENT MANNER; EXPERIMENTAL METHODOLOGY; LUNG SURFACTANTS; MARANGONI EFFECTS; NANOSTRUCTURED PARTICLES; PHYSIOLOGICAL FUNCTIONS; PULMONARY DRUG DELIVERY; SURFACE CHARACTERISTICS;

BIOLOGICAL ORGANS;

LUNG SURFACTANT; NANOPARTICLE;

ADSORPTION; AEROSOL; CHEMICAL COMPOSITION; HUMAN; HYDRODYNAMICS; HYDROPHILICITY; HYSTERESIS; IN VITRO STUDY; IN VIVO STUDY; INHALATION; LUNG; LUNG ALVEOLUS; LUNG DISEASE; MOLECULAR INTERACTION; PARTICLE SIZE; PHYSICAL CHEMISTRY; PHYSIOLOGICAL PROCESS; PREDICTION; REVIEW; SURFACE PROPERTY; SURFACE TENSION; THEORETICAL STUDY; ZETA POTENTIAL;

EID: 85039749442     PISSN: 13590294     EISSN: 18790399     Source Type: Journal    
DOI: 10.1016/j.cocis.2017.12.003     Document Type: Review

References (75)

1. Goerke, J., Surfactant and lung mechanics. Robertson, B., Van Golde, L.M.G., Batenburg, J.J., (eds.) Pulmonary surfactant: From molecular biology to clinical practice, 1992, Elsevier, Amsterdam, 165–192 A chapter describing the importance of the lung surfactant for the mechanics of breathing.
2. Copland, I.B., Post, M., Understanding the mechanisms of infant respiratory distress and chronic lung disease. Am J Respir Cell Mol Biol 26 (2002), 261–265.
3. Newman, S., Respiratory drug delivery. Essential theory and practice. 2009, RDD Online-VCU, Richmond A monograph on technical aspects of inhalation aerosols and inhaling devices, including the regulatory requirements.
4. Sosnowski, T.R., Selected engineering and physicochemical aspects of systemic drug delivery by inhalation. Curr Pharm Des 22 (2016), 2453–2462 A review on selected aspects of inhalation drug delivery and particle-lung interactions.
5. Sosnowski, T.R., Kramek-Romanowska, K., Predicted deposition of e-cigarette aerosol in the human lungs. J Aerosol Med Pulm Drug Deliv 29 (2016), 299–309.
6. Lang, C.J., Postle, A.D., Orgeig, S., Possmayer, F., Bernhard, W., Panda, A.K., et al. Dipalmitoylphosphatidylcholine is not the major surfactant phospholipid species in all mammals. Am J Physiol Regul Integr Comp Physiol 289 (2005), R1426–R1439.
7. Gradoń L., Podgórski, A., Hydrodynamical model of pulmonary clearance. Chem Eng Sci 44 (1989), 741–749 A paper explaining and modeling the pulmonary hydrodynamics and Marangoni flows in the lungs.
8. Podgórski, A., Gradoń L., An improved mathematical model of hydrodynamical self-cleansing of pulmonary alveoli. Ann Occup Hyg 37 (1993), 347–365.
9. Gradoń L., Podgórski, A., Sosnowski, T.R., Experimental and theoretical investigations of transport properties of DPPC monolayer. J Aerosol Med 9 (1996), 357–367 A paper describing the hydrodynamics of liquid layer in the Langmuir trough and particle driven by dynamic Marangoni effects.
10. Sosnowski, T.R., Dynamic effects in gas-liquid systems with the active interface. 2006, Publishing House of Warsaw University of Technology, Warsaw, Poland [book in Polish].
11. Notter, R.H., Taubold, R., Mavis, R.D., Hysteresis in saturated phospholipid films and its potential relevance for lung surfactant functions in vivo. Exp Lung Res 3 (1982), 109–127.
12. Lyklema, J., Fundamentals of interface and colloid science. 2000, Academic Press, London-San Diego A comprehensive and clearly-written book on various aspects interfacial science.
13. Wüstneck, R., Wüstneck, N., Moser, B., Karageorgieva, V., Pison, U., Surface dilatational behavior of pulmonary surfactant components spread on the surface of a pendant drop. 1. Dipalmitoyl phosphatidylcholine and surfactant protein C. Langmuir 18 (2002), 1119–1124 A paper describing an alternative method of studying dynamics of DPPC and mixed monolayers by pendant drop method.
14. Kondej, D., Sosnowski, T.R., Effect of clay nanoparticles on model lung surfactant: a potential marker of hazard from nanoaerosol inhalation. Environ Sci Pollut Res 23 (2016), 4660–4669.
15. Sosnowski, T.R., Gradoń L., Podgórski, A., Influence of insoluble aerosol deposits on the surface activity of the pulmonary surfactant: a possible mechanism of alveolar clearance retardation. Aerosol Sci Technol 32 (2000), 52–60.
16. Podgórski, A., Gradoń L., Function of the pulmonary surfactant in the clearance of respiratory bronchioles: a mathematical model. Chem Eng Commun 110 (1991), 143–162 A paper modeling the bronchiolar flows induced by static surface tension gradients.
17. Ashgarian, B., Hofmann, W., Miller, F.J., Mucociliary clearance of insoluble particles from the tracheobronchial airways of the human lung. J Aerosol Sci 32 (2001), 817–832 A paper analyzing particle retention in various parts of bronchial tree based on the mathematical modeling of mucociliary transport rate.
18. Smith, D.J., Gaffney, E.A., Blake, J.R., A viscoelastic traction layer model of mucociliary transport. Bull Math Biol 69 (2007), 289–327.
19. Zuo, Y.Y., Li, D., Acosta, E., Cox, P.N., Neumann, A.W., Effect of surfactant on interfacial gas transfer studied by axisymmetric drop shape analysis-captive bubble (ADSA-CB). Langmuir 21 (2005), 5446–5452.
20. Białecki, J., Hołyst, J.A., Linear stablity in a liquid layer with a surface velocity gradient. Phys Rev E, 67, 2003, 066311.
21. Gradoń L., Sosnowski, T.R., Mass transfer trough the gas-liquid interface at the presence of adsorbed active phospholipid monolayer. Stud Surf Sci Catal 133 (2001), 283–288.
22. Sosnowski, T.R., Gradoń L., Skoczek, M., Droździel, H., Experimental evaluation of importance of the pulmonary surfactant for oxygen transfer rate in human lungs. Int J Occup Saf Ergon 4 (1998), 391–409.
23. Kramek-Romanowska, K., Odziomek, M., Sosnowski, T.R., Dynamic tensiometry studies on interactions of novel therapeutic inhalable powders with model pulmonary surfactant at the air-water interface. Colloids Surf A Physicochem Eng Asp 480 (2015), 149–158.
24. Sosnowski, T.R., Dymowski, K., Mazurkiewicz-Pawlicka, M., Inactivation of pulmonary surfactant by nanoparticles - in vitro studies by DSA method. J Aerosol Med Pulm Drug Deliv, 30(3), 2017, A34.
25. Notter, R.H., Lung surfactants: Basic science and clinical applications. 2000, CRC Press, New York -Basel A comprehensive book on the lung surfactant viewed from biological, physico-chemical and medical perspective.
26. Schürch, S., Gehr, P., Im, Hof V., Geiser, M., Green, F., Surfactant displaces particles toward the epithelium in airways and alveoli. Respir Physiol Neurobiol 80 (1980), 17–32 An early paper analyzing the wetting of particles by surfactant and their possible sinking in the lung fluids.
27. Gehr, P., Geiser, M., Im, Hof V., Schurch, S., Waber, U., Baumann, M., Surfactant and inhaled particles in the conducting airways: structural, stereological, and biophysical aspects. Microsc Res Tech 26 (1993), 423–436.
28. Schleh, C., Hohlfeld, J.M., Interaction of nanoparticles with the pulmonary surfactant system. Inhal Toxicol 21 (2009), 97–103.
29. Nel, A., Xia, T., Mädler, L., Li, N., Toxic potential of materials at the nanolevel. Science 311:5761 (2006), 622–627 An excellent input to the understanding nanomaterials toxicity.
30. Wallace, W.E., Keane, M.J., Murray, D.K., Chisholm, W.P., Maynard, A.D., Ong, T.M., Phospholipid lung surfactant and nanoparticle surface toxicity: lessons from diesel soots and silicate dusts. J Nanopart Res 9 (2007), 23–38 A review of toxic effects mediated by nanoparticles interaction with the lung surfactant.
31. Nel, A.E., Mädler, L., Velegol, D., Xia, T., Hoek, E.M.V., Somasundaran, P., et al. Understanding biophysicochemical interactions at the nano–bio interface. Nat Mater 8 (2009), 543–557 Discussion of physico-chemical aspects of nanomaterial-interface interactions in biological systems.
32. Jabłczyńska, K., Janczewska, M., Kulikowska, A., Sosnowski, T.R., Preparation and characterization of biocompatible polymer particles as potential nanocarriers for inhalation therapy. Int J Polym Sci, 2015, 2015, 763020 [8 pages].
33. Sung, J.C., Pulliam, B.L., Edwards, D.A., Nanoparticles for drug delivery to the lungs. Trends Biotechnol 25 (2007), 563–570 A paper indicating possibilities in designing nanosized and nanostructured particles for an improved inhalation therapy.
34. Kittelson, D.B., Engines and nanoparticles: a review. J Aerosol Sci 29 (1998), 575–588.
35. Sosnowski, T.R., Koliński, M., Gradoń L., Interactions of benzo[a]pyrene and diesel exhaust particulate matter with the lung surfactant system. Ann Occup Hyg 55 (2011), 329–338.
36. Sosnowski, T.R., Koliński, M., Gradoń L., Alteration of surface properties of dipalmitoyl phosphatidylcholine by benzo[a]pyrene: a model of pulmonary effects of diesel exhaust inhalation. J Biomed Nanotechnol 8 (2012), 818–825 A paper showing changes in model biosurface induced by aromatic compound - studied by experiments and molecular dynamics.
37. Kodama, A.T., Kuo, C.-C., Boatwright, T., Dennin, M., Investigating the effect of particle size on pulmonary surfactant phase behavior. Biophys J 107 (2014), 1573–1581.
38. Dwivedi, M.V., Harishchandra, R.K., Koshkina, O., Maskos, M., Galla, H.-J., Size influences the effect of hydrophobic nanoparticles on lung surfactant model systems. Biophys J 106:1 (2014), 289–298.
39. Guzmán, E., Liggieri, L., Santini, E., Ferrari, M., Ravera, F., Effect of hydrophilic and hydrophobic nanoparticles on the surface pressure response of DPPC monolayers. J Phys Chem C 115 (2011), 21715–21722.
40. Guzmán, E., Santini, E., Zabiegaj, D., Ferrari, M., Liggieri, L., Ravera, F., Interaction of carbon black particles and dipalmitoylphosphatidylcholine at the water/air interface: thermodynamics and rheology. J Phys Chem C 44 (2015), 26937–26947 A paper explaining the influence of hydrophobic particles on DPPC monolayer architecture and dynamics.
41. Sheridan, A.J., Slater, J.M., Arnold, T.A., Campbell, R.A., Thompson, K.C., Changes to DPPC domain structure in the presence of carbon nanoparticles. Langmuir 33 (2017), 10374–10384.
42. Kendall, M., Brown, L., Trought, K., Molecular adsorption at particle surfaces: a PM toxicity mediation mechanism. Inhal Toxicol 16:Suppl. 1 (2004), 99–105 A paper analyzing a possible route of the lung toxicity of inhaled particles.
43. Wang, L., Castranova, V., Mishra, A., Chen, B., Mercer, R.R., Schwegler-Berry, D., et al. Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies. Part Fibre Toxicol, 7, 2010, 31.
44. Seiffert, J., Hussain, F., Wiegman, C., Li, F., Bey, L., Baker, W., et al. Pulmonary toxicity of instilled silver nanoparticles: influence of size, coating and rat strain. PLoS ONE, 10, 2015, e0119726.
45. 2 particles and in the presence of phospho(lipases) by zeta potential and effective diameter measurements. Powder Technol 213 (2011), 141–147.
46. Kanishtha, T., Banerjee, R., Venkataraman, C., Effect of particle emissions from biofuel combustion on surface activity of model and therapeutic pulmonary surfactants. Environ Toxicol Pharmacol 22 (2006), 325–333.
47. Guzmán, E., Santini, E., Ferrari, M., Liggieri, L., Ravera, F., Interfacial properties of mixed DPPC–hydrophobic fumed silica nanoparticle layers. J Phys Chem C 119 (2015), 21024–21034.
48. Orsi, D., Rimoldi, T., Guzmán, E., Liggieri, L., Ravera, F., Ruta, B., et al. Hydrophobic silica nanoparticles induce gel phases in phospholipid monolayers. Langmuir 32 (2016), 4868–4876.
49. Harishchandra, R.K., Saleem, M., Galla, H.-J., Nanoparticle interaction with model lung surfactant monolayers. J R Soc Interface 7 (2010), S15–S26.
50. Tatur, S., Badia, A., Influence of hydrophobic alkylated gold nanoparticles on the phase behavior of monolayers of DPPC and clinical lung surfactant. Langmuir 28 (2012), 628–639.
51. Valle, R.P., Huang, C.L., Loo, J.S.C., Zuo, Y.Y., Increasing hydrophobicity of nanoparticles intensifies lung surfactant film inhibition and particle retention. ACS Sustain Chem Eng 2 (2014), 1574–1580.
52. Hu, G., Jiao, B., Shi, X., Valle, R.P., Fan, Q., Zuo, Y.Y., Physicochemical properties of nanoparticles regulate translocation across pulmonary surfactant monolayer and formation of lipoprotein corona. ACS Nano 7 (2013), 10525–10533.
53. Mills, N.L., Amin, N., Robinson, S.D., Anand, A., Davies, J., Patel, D., et al. Do inhaled carbon nanoparticles translocate directly into the circulation in humans?. Am J Respir Crit Care Med 173 (2006), 426–431.
54. Guzmán, E., Liggieri, L., Santini, E., Ferrari, M., Ravera, F., Influence of silica nanoparticles on dilational rheology of DPPC–palmitic acid Langmuir monolayers. Soft Matter 8 (2012), 3938–3948.
55. Orsi, D., Guzmán, E., Liggieri, L., Ravera, F., Ruta, B., Chushkin, Y., et al. 2D dynamical arrest transition in a mixed nanoparticle-phospholipid layer studied in real and momentum spaces. Sci Rep, 5, 2016, 17930, 10.1038/srep17930 A paper describing the peculiar effect of nanoparticles on highly compressed lipid monolayer.
56. Guzmán, E., Ferrari, M., Santini, E., Liggieri, L., Ravera, F., Effect of silica nanoparticles on the interfacial properties of a canonical lipid mixture. Colloids Surf B Biointerfaces 136 (2015), 971–980.
57. Farnoud, A.M., Fiegel, J., Low concentrations of negatively charged sub-micron particles alter the microstructure of DPPC at the air–water interface. Colloids Surf A Physicochem Eng Asp 415 (2012), 320–327.
58. Fan, Q., Wang, Y.E., Zhao, X., Loo, J.S., Zuo, Y.Y., Adverse biophysical effects of hydroxyapatite nanoparticles on natural pulmonary surfactant. ACS Nano 5 (2011), 6410–6416.
59. Guzmán, E., Santini, E., Ferrari, M., Liggieri, L., Ravera, F., Effect of the incorporation of nanosized titanium dioxide on the interfacial properties of 1,2-dipalmitoyl-sn-glycerol-3-phosphocholine Langmuir monolayers. Langmuir 33 (2017), 10715–10725.
60. Mukherjee, D., Porter, A., Ryan, M., Schwander, S., Chung, K.F., Tetley, T., et al. Modeling in vivo interactions of engineered nanoparticles in the pulmonary alveolar lining fluid. Nanomaterials 5 (2015), 1223–1249.
61. Choe, S., Chang, R., Jeon, J., Violi, A., Molecular dynamics simulation study of a pulmonary surfactant film interacting with a carbonaceous nanoparticle. Biophys J 95 (2008), 4102–4114.
62. Xu, Y., Deng, L., Ren, H., Zhang, X., Huang, F., Yue, T., Transport of nanoparticles across pulmonary surfactant monolayer: a molecular dynamics study. Phys Chem Chem Phys 19 (2017), 17568–17576 Theoretical analysis of particle transfer across the lipid monolayer.
63. Ratoi, M., Hoet, P.H.M., Crossley, A., Dobson, P., Impact of lung surfactant on wettability and cytotoxicity of nanoparticles. RSC Adv, 4, 2014, 20573 A paper discussing the alterations in nanoparticles properties on contact with the lung surfactant.
64. Kondej, D., Sosnowski, T.R., Alteration of biophysical activity of pulmonary surfactant by aluminosilicate nanoparticles. Inhal Toxicol 25 (2013), 77–83.
65. Kondej, D., Sosnowski, T.R., Physicochemical mechanisms of mineral nanoparticles effects on pulmonary gas/liquid interface studied in model systems. Physicochem Probl Miner Process 50 (2014), 55–67.
66. Whitwell, H., Mackay, R.-M., Elgy, C., Morgan, C., Griffiths, M., Clark, H., et al. Nanoparticles in the lung and their protein corona: the few proteins that count. Nanotoxicology 10 (2016), 1385–1394.
67. Kendall, M., Fine airborne urban particles (PM2.5) sequester lung surfactant and amino acids from human lung lavage. Am J Physiol Lung Cell Mol Physiol 293 (2007), L1053–L1058.
68. Schleh, C., Kreyling, W.G., Lehr, C.-M., Pulmonary surfactant is indispensable in order to simulate the in vivo situation. Part Fibre Toxicol, 10, 2013, 6.
69. Bihari, P., Vippola, M., Schultes, S., Praetner, M., Khandoga, A.G., Reichel, C.A., et al. Optimized dispersion of nanoparticles for biological in vitro and in vivo studies. Part Fibre Toxicol, 5, 2008, 14.
70. Valle, R.P., Wu, T., Zuo, Y.Y., Biophysical influence of airborne carbon nanomaterials on natural pulmonary surfactant. ACS Nano 5 (2015), 5413–5421.
71. Farnoud, A.M., Fiegel, J., Calf lung surfactant recovers surface functionality after exposure to aerosols containing polymeric particles. J Aerosol Med Pulm Drug Deliv 29 (2016), 10–23 A paper showing the new method of particle introduction to the air/liquid interface.
72. Sosnowski, T.R., Gradoń L., Iskandar, F., Okuyama, K., Interaction of deposited aerosol particles with the alveolar liquid layer. Gradoń L., Marijnissen, J., (eds.) Optimization of aerosol drug delivery, 2003, Kluwer, Dordrecht, 205–216.
73. Sosnowski, T.R., Nanosized and nanostructured particles in pulmonary drug delivery. J. Nanosci. Nanotechnol. 15 (2015), 3476–3487.
74. Sosnowski, T.R., Sorption-induced Marangoni microflows in the pulmonary surfactant system. Inz. Chem. Proces. 22 (2001), 251–267.
75. Bakshi, M.S., Zhao, L., Smith, R., Possmayer, F., Petersen, N.O., Metal nanoparticle pollutants interfere with pulmonary surfactant function in vitro. Biophys. J. 94 (2008), 855–868.