Alteration of surface properties of dipalmitoyl phosphatidylcholine by benzo[a]pyrene: A model of pulmonary effects of diesel exhaust inhalation

Journal of Biomedical Nanotechnology

Volumn 8, Issue 5, 2012, Pages 818-825

  Sosnowski, Tomasz R ^a   Koliński, Michał ^b   Gradon, Leon ^a  

^a WARSAW UNIVERSITY OF TECHNOLOGY   (Poland)

^b INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

Author keywords

Diesel exhaust; Lung surfactant; Molecular dynamics; PAHs; Surface activity

Indexed keywords

BENZO[A]PYRENE; CONCENTRATION-DEPENDENT; DIESEL EXHAUSTS; DIPALMITOYL PHOSPHATIDYLCHOLINE; HEALTH EFFECTS; HYDROCARBON CHAINS; INTERFACIAL LAYER; LIPID MEMBRANES; LUNG SURFACTANTS; MOLECULAR DYNAMICS SIMULATIONS; PAHS; PHOSPHOLIPID FILMS; PHOSPHOLIPID MOLECULES; PULMONARY SURFACTANTS; SURFACE ACTIVITIES; SURFACE COMPRESSIBILITY;

HYDROCARBONS; MOLECULAR DYNAMICS; MOLECULES; MONOLAYERS; SURFACE ACTIVE AGENTS; SURFACE PROPERTIES;

PHOSPHOLIPIDS;

BENZO[A]PYRENE; DIPALMITOYLPHOSPHATIDYLCHOLINE; HYDROCARBON; PHOSPHOLIPID;

ARTICLE; EXHAUST GAS; FILM; HYDROPHOBICITY; LIPID MEMBRANE; LUNG; MEMBRANE FLUIDITY; MOLECULAR DYNAMICS; MOLECULE; MONOLAYER CULTURE; PHYSICAL CHEMISTRY; SURFACE PROPERTY;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; AIR POLLUTANTS; BENZOPYRENES; COMPUTER SIMULATION; MODELS, CHEMICAL; MODELS, MOLECULAR; PULMONARY SURFACTANTS; SURFACE PROPERTIES; VEHICLE EMISSIONS;

EID: 84865124338     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2012.1436     Document Type: Article

References (32)

1. H. Burtscher, Physical characterization of particulate emissions from diesel engines: A review. J. Aerosol Sci. 36, 896 (2005).
2. M. M. Maricq, Chemical characterization of particulate emissions from diesel engines: A review. J. Aerosol Sci. 38, 1079 (2007).
3. M. Ono-Ogasawara and T. J. Smith, Diesel exhaust particles in the work environment and their analysis. Industrial Health 42, 389 (2004).
4. T. C. Bailey and R. A. W. Veldhuizen, Lung surfactant function and disorder, edited by K. Nag, Taylor and Francis, Boca Raton (2008), Chap. 15, pp. 359-381.
5. L. Gradoń and A. Podgórski, hydrodynamical model of pulmonary clearance. Chem. Eng. Sci. 44, 741 (1989).
6. T. R. Sosnowski, L. Gradon, and A. Podgórski, Influence of insoluble aerosol deposits on the surface activity of the pulmonary surfactant: A possible mechanism of alveolar clearance retardation? Aerosol Sci. Technol. 32, 52 (2000).
7. A. Moskal, T. R. Sosnowski, and L. Gradoń, Environmental and Medical Aerosol Nanoparticles. Inhalation and Health Effects, edited by J. C. M. Marijnissen and L. Gradoń, Springer, Dordrecht (2010), Chap. 7, pp. 113-144.
8. T. R. Sosnowski, L. Gradoń, F. Iskandar, and K. Okuyama, Optimization of Aerosol Drug Delivery, edited by L. Gradoń and J. Marijnissen, Kluwer Academic Publishers, Dordrecht (2003), pp. 205-216.
9. M. S. Bakhsi, L. Zhao, R. Smith, F. Possmayer, and N. O. Petersen, Metal nanoparticle pollutants interfere with pulmonary surfactant function in vitro. Biophys. J. 94, 855 (2008).
10. D. Kondej and T. R. Sosnowski, The influence of metal-containing occupational dust on pulmonary surfactant activity. Chem. Eng. Transact. 19, 315 (2010).
11. T. R. Sosnowski, M. Koliński, and L. Gradoń, Interactions of benzo[a]pyrene and diesel exhaust particulate matter with the lung surfactant system. Ann. Occup. Hyg. 55, 329 (2011).
12. C.-E. Bostrom, P. Gerde, A. Hanberg, B. Jernström, C. Johansson, T. Kyrklund, A. Rannug, M. Törnqvist, K. Victorin, and R. Westerholm, Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air. Envir. Health Persp. 110, 451 (2002).
13. K. P. Miller and K. S. Ramos, Impact of cellular metabolism on the biological effects of benzo[a]pyrene and related hydrocarbons. Drug Metab. Rev. 33, 1 (2001).
14. J. Sherley, M. Amrein, and Z. Leonenko, Pulmonary surfactant self-assembles into a functional film of defined molecular architecture irrespective of concentration and solvent of the spreading solution: A fluorescence and atomic force microscopy study. J. Biomedical Nanotechnology 4, 210 (2008).
15. A. Skibinsky, R. M. Venable, and R. W. Pastor, A molecular dynamics study of the response of lipid bilayers and monolayers to trehalose. Biophys. J. 89, 4111 (2005).
16. J. Sykora, S. Yilma, W. C. Neely, and V. Vodyanoy, Amphotericin B and cholesterol in monolayers and bilayers. Langmuir 19, 858 (2003).
17. A. W. Schuttelkopf and D. M. van Aalten, PRODRG: A tool for high-throughput crystallography of protein-ligand complexes. Acta Crystallogr. D Biol. Crystallogr. 60, 1355 (2004).
18. D. van der Spoel, E. Lindahl, B. Hess, G. Groenhof, A. E. Mark, and H. J. C. Berendsen, GROMACS: Fast, flexible, and free. J. Comput. Chem. 26, 1701 (2005).
19. O. Berger, O. Edholm, and F. Jahnig, Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature. Biophys. J. 72, 2002 (1997).
20. D. van der Spoel, P. J. van Maaren, and H. J. C. Berendsen, Asystematic study of water models for molecular simulation: Derivation of water models optimized for use with a reaction field. J. Chem. Physics 108, 10220 (1998).
21. T. Darden, D. York, and L. Pedersen, Particle mesh Ewald: An N log(N) method for Ewald sums in large systems. J. Chem. Physics 98, 10089 (1993).
22. E. G. M. Vanquelef, G. Caron, J. C. Delepine, C. Cezard, P. Cieplak, and F.-Y. Dupradeau, R.E.D. Server: A web service designed to derive RESP and ESP charges of high quality and reproducibility and to generate force field libraries for new molecules and new molecular fragments, Université de Picardie Jules Verne - Burnham Institute for Medical Research (2009).
23. C. I. Bayly, P. Cieplak, W. Cornell, and P. A. Kollman, A well-behaved electrostatic potential based method using charge restraints for deriving atom-centered charges: The RESP model. J. Phys. Chem. 97, 10269 (1993).
24. W. Humphrey, A. Dalke, and K. Schulten, VMD: Visual molecular dynamics. J. Mol. Graph. 14, 27-8 (1996).
25. J. Lyklema, Fundamentals of Interface and Colloid Science, Academic Press, London-San Diego (2000).
26. B. Pastrana-Rios, C. Flach, J. Braunner, A. J. Mautone, and R. Mendelsohn, A direct test of the "squeeze-out" hypothesis of lung surfactant function. external reflection FT-IR at the air/water interface. Biochemistry 33, 5121 (1994).
27. J. F. Nagle, R. Zhang, S. Tristram-Nagle, W. Sun, H. I. Petrache, and R. M. Suter, X-ray structure determination of fully hydrated L alpha phase dipalmitoylphosphatidylcholine bilayers. Biophys. J. 70, 1419 (1996).
28. D. P. Tieleman and H. J. C. Berendsen, Molecular dynamics simulations of fully hydrated DPPC with different macroscopic boundary conditions and parameters. J. Chem. Physics 105, 4871 (1996).
29. S. H. White and W. C. Wimley, Membrane protein folding and stability: Physical principles. Ann. Rev. Biophys. Biomol. Struct. 28, 319 (1999).
30. P.-G. de Gennes, Scaling Concepts in Polymer Physics, Cornell University Press, Ithaca (1979).
31. A. Filippov, G. Oradd, and G. Lindblom, The effect of cholesterol on the lateral diffusion of phospholipids in oriented bilayers. Biophys. J. 84, 3079 (2003).
32. A. Podgórski, T. R. Sosnowski, and L. Gradoń, Deactivation of the pulmonary surfactant dynamics by toxic aerosols and gases. J. Aerosol Med. 14, 455 (2001).