West Africa 2013 ebola: From virus outbreak to humanitarian crisis

Current Topics in Microbiology and Immunology

Volumn 411, Issue , 2017, Pages 63-92

  Bausch, Daniel G ^a,b  

^a TULANE UNIVERSITY   (United States)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AFRICA; CULTURAL FACTOR; DISASTER; EBOLA HEMORRHAGIC FEVER; ECONOMIC RECESSION; EPIDEMIC; EVOLUTION; HUMAN; HUMANITARIAN DISASTER; INFECTION CONTROL; MORTALITY; NONHUMAN; POLITICS; PRIORITY JOURNAL; SOCIAL ASPECT; VIRUS TRANSMISSION; WEST AFRICA; COMMUNICABLE DISEASE; ECONOMICS; STATISTICS AND NUMERICAL DATA; VIROLOGY;

AFRICA, WESTERN; COMMUNICABLE DISEASES, EMERGING; DISEASE OUTBREAKS; HEMORRHAGIC FEVER, EBOLA; HUMANS;

EID: 85039459870     PISSN: 0070217X     EISSN: 21969965     Source Type: Book Series    
DOI: 10.1007/82_2017_69     Document Type: Chapter

References (70)

1. Akerlund E, Prescott J, Tampellini L (2015) Shedding of Ebola virus in an asymptomatic pregnant woman. N Engl J Med 372(25):2467–2469.
2. Baggi FM, Taybi A, Kurth A, Van Herp M, Di Caro A, Wolfel R et al (2014) Management of pregnant women infected with Ebola virus in a treatment centre in Guinea, June 2014. Euro Surveill: Bull Eur Sur Les Mal Transm = European Commun Dis Bull 19(49).
3. Baize S, Pannetier D, Oestereich L, Rieger T, Koivogui L, Magassouba N et al (2014) Emergence of Zaire Ebola virus disease in Guinea. N Engl J Med 371(15):1418–1425.
4. Bank TW (2016) The world bank fact sheet. The world bank.
5. Bausch DG, Rojek A (2016) West Africa 2013: re-examining Ebola. Microbiol Spectr 4(3).
6. Bausch DG, Schwarz L (2014) Outbreak of Ebola virus disease in Guinea: where ecology meets economy. PLoS Negl Trop Dis 8(7):e3056.
7. Bausch DG, Bangura J, Garry RF, Goba A, Grant DS, Jacquerioz FA et al (2014) A tribute to Sheik Humarr Khan and all the healthcare workers in West Africa who have sacrificed in the fight against Ebola virus disease: Mae we hush. Antiviral Res 111C:33–35.
8. Bird BH, Spengler Jr., Chakrabarti AK, Khristova ML, Sealy TK, Coleman-McCray JD et al (2016) Humanized mouse model of Ebola virus disease mimics the immune responses in human disease. J Infect Dis 213(5):703–711.
9. Bower H, Grass JE, Veltus E, Brault A, Campbell S, Basile AJ et al (2015) Delivery of an Ebola virus-positive stillborn infant in a rural community health center, Sierra Leone, January 2015. Am J Trop Med Hyg.
10. Brainard J, Pond K, Hooper L, Edmunds K, Hunter P (2016) Presence and persistence of Ebola or Marburg virus in patients and survivors: a rapid systematic review. PLoS Negl Trop Dis 10(2):e0004475.
11. Caluwaerts S, Fautsch T, Lagrou D, Moreau M, Modet Camara A, Gunther S et al (2015) Dilemmas in managing pregnant women with Ebola: 2 case reports. Clin Infect Dis: Off publ Infect Dis Soc Am.
12. Carroll MW, Matthews DA, Hiscox JA, Elmore MJ, Pollakis G, Rambaut A et al (2015) Temporal and spatial analysis of the 2014–2015 Ebola virus outbreak in West Africa. Nature 524(7563):97–101.
13. Christie A, Davies-Wayne GJ, Cordier-Lasalle T, Blackley DJ, Laney AS, Williams DE et al (2015) Possible sexual transmission of Ebola virus—Liberia, 2015. MMWR Morb Mortal Wkly Rep 64(17):479–481.
14. Deen GF, Knust B, Broutet N, Sesay FR, Formenty P, Ross C et al (2015) Ebola RNA persistence in semen of Ebola virus disease survivors—preliminary report. N Engl J Med.
15. Dhillon RS, Srikrishna D, Garry RF, Chowell G (2015) Ebola control: rapid diagnostic testing. Lancet Infect Dis 15(2):147–148.
16. Diallo B, Sissoko D, Loman NJ, Bah HA, Bah H, Worrell MC et al (2016) Resurgence of Ebola virus disease in Guinea linked to a survivor with virus persistence in seminal fluid for more than 500 days. Clin Infect Dis: Off Publ Infect Dis Soc Am 63(10):1353–1356.
17. Dunham EC, Banadyga L, Groseth A, Chiramel AI, Best SM, Ebihara H et al (2015) Assessing the contribution of interferon antagonism to the virulence of West African Ebola viruses. Nat Commun 6:8000.
18. Eggo RM, Watson CH, Camacho A, Kucharski AJ, Funk S, Edmunds WJ (2015) Duration of Ebola virus RNA persistence in semen of survivors: population-level estimates and projections. Euro surveillance: Bull Eur Sur Les Mal Transm = Eur Commun Dis Bull 20(48).
19. Elston JW, Moosa AJ, Moses F, Walker G, Dotta N, Waldman RJ et al (2015) Impact of the Ebola outbreak on health systems and population health in Sierra Leone. J Public Health.
20. Faye O, Boelle PY, Heleze E, Faye O, Loucoubar C, Magassouba N et al (2015) Chains of transmission and control of Ebola virus disease in Conakry, Guinea, in 2014: an observational study. Lancet Infect Dis 15(3):320–326.
21. Formenty P, Hatz C, Le Guenno B, Stoll A, Rogenmoser P, Widmer A (1999a) Human infection due to Ebola virus, subtype Cote d’Ivoire: clinical and biologic presentation. J Infect Dis 179(Suppl 1):S48–S53.
22. Formenty P, Boesch C, Wyers M, Steiner C, Donati F, Dind F et al (1999b) Ebola virus outbreak among wild chimpanzees living in a rain forest of Cote d’Ivoire. J Infect Dis 179(Suppl 1):S120–S126.
23. Franklin SM (2016) A comparison of personal protective standards: caring for patients with Ebola virus. Clin Nurse Spec 30(2):E1–E8.
24. Gire SK, Goba A, Andersen KG, Sealfon RS, Park DJ, Kanneh L et al (2014) Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science (New York, NY) 345(6202):1369–1372.
25. Hassanin A, Nesi N, Marin J, Kadjo B, Pourrut X, Leroy E et al (2016) Comparative phylogeography of African fruit bats (Chiroptera, Pteropodidae) provide new insights into the outbreak of Ebola virus disease in West Africa, 2014–2016. CR Biol 339(11–12):517–528.
26. Hayden FG, Friede M, Bausch DG (2017) Experimental therapies for Ebola virus disease: what have we learned? J Infect Dis.
27. Henao-Restrepo AM, Camacho A, Longini IM, Watson CH, Edmunds WJ, Egger M et al (2016) Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ca Suffit!). Lancet.
28. Hersi M, Stevens A, Quach P, Hamel C, Thavorn K, Garritty C et al (2015) Effectiveness of personal protective equipment for healthcare workers caring for patients with filovirus disease: a rapid review. PLoS ONE 10(10):e0140290.
29. Hofmann-Winkler H, Gnirss K, Wrensch F, Pohlmann S (2015) Comparative analysis of host cell entry of Ebola virus from Sierra Leone, 2014, and Zaire, 1976. J Infect Dis 212(Suppl 2):S172–S180.
30. Holmes EC, Dudas G, Rambaut A, Andersen KG (2016) The evolution of Ebola virus: insights from the 2013–2016 epidemic. Nature 538(7624):193–200.
31. Howlett P, Brown C, Helderman T, Brooks T, Lisk D, Deen G et al (2016) Ebola virus disease complicated by late-onset encephalitis and polyarthritis Sierra Leone. Emerg Infect Dis 22(1):150–152.
32. Huttner A, Dayer JA, Yerly S, Combescure C, Auderset F, Desmeules J et al (2015) The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial. Lancet Infect Dis 15(10):1156–1166.
33. Jacobs M, Rodger A, Bell DJ, Bhagani S, Cropley I, Filipe A et al (2016) Late Ebola virus relapse causing meningoencephalitis: a case report. Lancet.
34. Keita M, Duraffour S, Loman NJ, Rambaut A, Diallo B, Magassouba N et al (2016) Unusual Ebola virus chain of transmission, Conakry, Guinea, 2014–2015. Emerg Infect Dis 22(12):2149–2152.
35. Kuhn JH, Andersen KG, Baize S, Bao Y, Bavari S, Berthet N et al (2014) Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014. Viruses 6(11):4760–4799.
36. Lau MS, Dalziel BD, Funk S, McClelland A, Tiffany A, Riley S et al (2017) Spatial and temporal dynamics of superspreading events in the 2014–2015 West Africa Ebola epidemic. Proc Natl Acad Sci USA 114(9):2337–2342.
37. Li X, Zai J, Liu H, Feng Y, Li F, Wei J et al (2016) The 2014 Ebola virus outbreak in West Africa highlights no evidence of rapid evolution or adaptation to humans. Sci Rep 6:35822.
38. Mari Saez A, Weiss S, Nowak K, Lapeyre V, Zimmermann F, Dux A et al (2014) Investigating the zoonotic origin of the West African Ebola epidemic. EMBO Mol Med 7(1):17–23.
39. Marzi A, Robertson SJ, Haddock E, Feldmann F, Hanley PW, Scott DP et al (2015a) EBOLA VACCINE. VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain. Science (New York, NY) 349(6249):739–742.
40. Marzi A, Feldmann F, Hanley PW, Scott DP, Gunther S, Feldmann H (2015b) Delayed disease progression in cynomolgus macaques infected with Ebola virus makona strain. Emerg Infect Dis 21(10):1777–1783.
41. Mate SE, Kugelman Jr., Nyenswah TG, Ladner JT, Wiley MR, Cordier-Lassalle T et al (2015) Molecular evidence of sexual transmission of Ebola virus. N Engl J Med.
42. Matranga CB, Andersen KG, Winnicki S, Busby M, Gladden AD, Tewhey R et al (2014) Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples. Genome Biol 15(11):519.
43. Meltzer MI, Atkins CY, Santibanez S, Knust B, Petersen BW, Ervin ED et al (2014) Estimating the future number of cases in the Ebola epidemic–Liberia and Sierra Leone, 2014–2015. MMWR Suppl 63(3):1–14.
44. Moon S, Sridhar D, Pate MA, Jha AK, Clinton C, Delaunay S et al (2015) Will Ebola change the game? Ten essential reforms before the next pandemic. The report of the Harvard-LSHTM Independent Panel on the Global Response to Ebola. Lancet 386(10009):2204–2221.
45. Nations U (ed) (1948) The universal declaration of human rights. UN Gen Assem, New York, United Nations.
46. NIH (2015) Study of Ebola survivors opens in Liberia [cited 2016 April 21]. http://www.nih.gov/news-events/news-releases/study-ebola-survivors-opens-liberia.
47. Ning YJ, Deng F, Hu Z, Wang H (2017) The roles of Ebolavirus glycoproteins in viral pathogenesis. Virol Sin. 32(1):3–15.
48. Oduyebo T, Pineda D, Lamin M, Leung A, Corbett C, Jamieson DJ (2015) A pregnant patient with Ebola virus disease. Obstet Gynecol.
49. Osterholm MT, Moore KA, Kelley NS, Brosseau LM, Wong G, Murphy FA et al (2015) Transmission of Ebola viruses: what we know and what we do not know. mBio 6(2):e00137.
50. Park DJ, Dudas G, Wohl S, Goba A, Whitmer SL, Andersen KG et al (2015) Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone. Cell 161(7):1516–1526.
51. Parpia AS, Ndeffo-Mbah ML, Wenzel NS, Galvani AP (2016) Effects of response to 2014–2015 Ebola outbreak on deaths from Malaria, HIV/AIDS, and tuberculosis, West Africa. Emerg Infect Dis 22(3):433–441.
52. Quick J, Loman NJ, Duraffour S, Simpson JT, Severi E, Cowley L et al (2016) Real-time, portable genome sequencing for Ebola surveillance. Nature 530(7589):228–232.
53. Simon-Loriere E, Faye O, Faye O, Koivogui L, Magassouba N, Keita S et al (2015) Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic. Nature 524(7563):102–104.
54. Sozhamannan S, Holland MY, Hall AT, Negron DA, Ivancich M, Koehler JW et al (2015) Evaluation of signature erosion in Ebola virus due to genomic drift and its impact on the performance of diagnostic assays. Viruses 7(6):3130–3154.
55. System Ebola Epidemiology Team IM (2014) Update: Ebola virus disease epidemic—west Africa, November 2014. MMWR Morbidity and mortality weekly report 63(46):1064–1066.
56. UNICEF (2016) Children hardest hit New York, USA [cited 2017 April 23]. https://www.unicef.org/emergencies/ebola/75941_76202.html.
57. Urbanowicz RA, McClure CP, Sakuntabhai A, Sall AA, Kobinger G, Muller MA, et al (2016) Human adaptation of Ebola virus during the West African outbreak. Cell 167(4):1079–1087 e5.
58. Uyeki TM, Mehta AK, Davey RT Jr., Liddell AM, Wolf T, Vetter P et al (2016) Clinical management of Ebola virus disease in the United States and Europe. N Engl J Med 374(7):636–646.
59. Varkey JB, Shantha JG, Crozier I, Kraft CS, Lyon GM, Mehta AK et al (2015) Persistence of Ebola virus in ocular fluid during convalescence. N Engl J Med.
60. Vetter P, Fischer WA, 2nd, Schibler M, Jacobs M, Bausch DG, Kaiser L (2016a) Ebola virus shedding and transmission: review of current evidence. J Infect Dis.
61. Vetter P, Kaiser L, Schibler M, Ciglenecki I, Bausch DG (2016b) Sequelae of Ebola virus disease: the emergency within the emergency. Lancet Infect Dis.
62. Whitmer SL, Albarino C, Shepard SS, Dudas G, Sheth M, Brown SC et al (2016) Preliminary evaluation of the effect of investigational Ebola virus disease treatments on viral genome sequences. J Infect Dis 214(Suppl 3):S333–S341.
63. WHO (2008) Interim infection control recommendations for care of patients with suspected or confirmed Filovirus (Ebola, Marburg) Haemorrhagic Fever.
64. WHO (2014a) Ground zero in Guinea: the Ebola outbreak smoulders—undetected—for more than 3 months. http://www.who.int/csr/disease/ebola/ebola-6-months/guinea/en/.
65. WHO (2014b) Ebola virus disease in Guinea. http://www.afro.who.int/en/clusters-a-programmes/dpc/epidemic-a-pandemic-alert-and-response/outbreak-news/4063-ebola-hemorrhagic-fever-in-guinea.html.
66. WHO (2015a) Ebola Situation Report—4 November 2015. http://apps.who.int/ebola/current-situation/ebola-situation-report-4-November-2015.
67. WHO (2015b) Ebola situation report—2 December 2015. http://apps.who.int/ebola/current-situation/ebola-situation-report-2-December-2015.
68. WHO (2015c) Ebola virus disease (EVD) in West Africa: an extraordinary epidemic. Releve epidemiologique hebdomadaire/section d’hygiene du secretariat de la societe des nations = weekly epidemiological record/ health section of the secretariat of the league of nations. 90(10):89–96.
69. WHO (2016a) Clinical care for survivors of Ebola virus disease. Interim guidance Geneva, Switzerland: WHO [cited 2016 January 24, 2016]. http://apps.who.int/csr/resources/publications/ebola/guidance-survivors/en/index.html.
70. WHO (2016b) WHO health emergencies program geneva, Switzerland: WHO [cited 2017 April 23]. http://www.who.int/about/who_reform/emergency-capacities/emergency-programme/en/.