Evaluation of signature erosion in ebola virus due to genomic drift and its impact on the performance of diagnostic assays

Viruses

Volumn 7, Issue 6, 2015, Pages 3130-3154

  Sozhamannan, Shanmuga ^a,b   Holland, Mitchell Y ^c   Hall, Adrienne T ^d   Negrón, Daniel A ^c   Ivancich, Mychal ^c   Koehler, Jeffrey W ^d   Minogue, Timothy D ^d   Campbell, Catherine E ^e   Berger, Walter J ^c   Christopher, George W ^f   Goodwin, Bruce G ^a   Smith, Michael A ^a  

^a Ft Detrick   (United States)

^b Tauri Group   (United States)

^c NOBLIS   (United States)

^d UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^e DCE consulting   (United States)

^f Medical Countermeasure Systems Joint Vaccine Acquisition Program   (United States)

Author keywords

BioVelocity; EBOV; PSET; QRT PCR; Signature erosion; Western African outbreak; WGS

Indexed keywords

VIRUS RNA;

ARTICLE; CLINICAL ASSESSMENT TOOL; EBOLAVIRUS; GENETIC DRIFT; NONHUMAN; PCR SIGNATURE EROSION TOOL; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDATION PROCESS; DIAGNOSTIC ERROR; GENETICS; HEMORRHAGIC FEVER, EBOLA; HUMAN; MOLECULAR DIAGNOSIS; PROCEDURES; VIROLOGY; VIRUS GENOME;

EBOLA VIRUS;

DIAGNOSTIC ERRORS; EBOLAVIRUS; GENETIC DRIFT; GENOME, VIRAL; HEMORRHAGIC FEVER, EBOLA; HUMANS; MOLECULAR DIAGNOSTIC TECHNIQUES; SENSITIVITY AND SPECIFICITY;

EID: 84935009609     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v7062763     Document Type: Article

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