-
1
-
-
0037109183
-
Switching metabolic genes to build a better heart
-
Taegtmeyer H, Switching metabolic genes to build a better heart. Circulation 2002 106 2043 2045
-
(2002)
Circulation
, vol.106
, pp. 2043-2045
-
-
Taegtmeyer, H.1
-
2
-
-
34547590901
-
Metabolic mechanisms in heart failure
-
Ashrafian H, Frenneaux MP, Opie LH, Metabolic mechanisms in heart failure. Circulation 2007 116 434 448. doi: 10.1161/CIRCULATIONAHA.107.702795.
-
(2007)
Circulation
, vol.116
, pp. 434-448
-
-
Ashrafian, H.1
Frenneaux, M.P.2
Opie, L.H.3
-
3
-
-
33947239659
-
The failing heart-an engine out of fuel
-
Neubauer S, The failing heart-an engine out of fuel. N Engl J Med 2007 356 1140 1151. doi: 10.1056/NEJMra063052.
-
(2007)
N Engl J Med
, vol.356
, pp. 1140-1151
-
-
Neubauer, S.1
-
4
-
-
67649209841
-
Increased glucose uptake and oxidation in mouse hearts prevent high fatty acid oxidation but cause cardiac dysfunction in diet-induced obesity
-
Yan J, Young ME, Cui L, Lopaschuk GD, Liao R, Tian R, Increased glucose uptake and oxidation in mouse hearts prevent high fatty acid oxidation but cause cardiac dysfunction in diet-induced obesity. Circulation 2009 119 2818 2828. doi: 10.1161/CIRCULATIONAHA.108.832915.
-
(2009)
Circulation
, vol.119
, pp. 2818-2828
-
-
Yan, J.1
Young, M.E.2
Cui, L.3
Lopaschuk, G.D.4
Liao, R.5
Tian, R.6
-
5
-
-
74949133862
-
Myocardial fatty acid metabolism in health and disease
-
Lopaschuk GD, Ussher JR, Folmes CD, Jaswal JS, Stanley WC, Myocardial fatty acid metabolism in health and disease. Physiol Rev 2010 90 207 258. doi: 10.1152/physrev.00015.2009.
-
(2010)
Physiol Rev
, vol.90
, pp. 207-258
-
-
Lopaschuk, G.D.1
Ussher, J.R.2
Folmes, C.D.3
Jaswal, J.S.4
Stanley, W.C.5
-
6
-
-
79955365919
-
Glucose metabolism and cardiac hypertrophy
-
Kolwicz SC Jr, Tian R, Glucose metabolism and cardiac hypertrophy. Cardiovasc Res 2011 90 194 201. doi: 10.1093/cvr/cvr071.
-
(2011)
Cardiovasc Res
, vol.90
, pp. 194-201
-
-
Kolwicz, S.C.1
Tian, R.2
-
7
-
-
33750110683
-
Fuel metabolism in starvation
-
Cahill GF Jr, Fuel metabolism in starvation. Annu Rev Nutr 2006 26 1 22. doi: 10.1146/annurev.nutr.26.061505.111258.
-
(2006)
Annu Rev Nutr
, vol.26
, pp. 1-22
-
-
Cahill, G.F.1
-
8
-
-
26844561663
-
Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization
-
Luptak I, Balschi JA, Xing Y, Leone TC, Kelly DP, Tian R, Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization. Circulation 2005 112 2339 2346. doi: 10.1161/CIRCULATIONAHA.105.534594.
-
(2005)
Circulation
, vol.112
, pp. 2339-2346
-
-
Luptak, I.1
Balschi, J.A.2
Xing, Y.3
Leone, T.C.4
Kelly, D.P.5
Tian, R.6
-
9
-
-
70449591256
-
Substrate utilization by the failing human heart by direct quantification using arterio-venous blood sampling
-
Funada J, Betts TR, Hodson L, Humphreys SM, Timperley J, Frayn KN, Karpe F, Substrate utilization by the failing human heart by direct quantification using arterio-venous blood sampling. PLoS One 2009 4 e7533. doi: 10.1371/journal.pone.0007533.
-
(2009)
PLoS One
, vol.4
, pp. e7533
-
-
Funada, J.1
Betts, T.R.2
Hodson, L.3
Humphreys, S.M.4
Timperley, J.5
Frayn, K.N.6
Karpe, F.7
-
10
-
-
84975775436
-
Evidence for intramyocardial disruption of lipid metabolism and increased myocardial ketone utilization in advanced human heart failure
-
Bedi KC Jr, Snyder NW, Brandimarto J, Aziz M, Mesaros C, Worth AJ, Wang LL, Javaheri A, Blair IA, Margulies KB, Rame JE, Evidence for intramyocardial disruption of lipid metabolism and increased myocardial ketone utilization in advanced human heart failure. Circulation 2016 133 706 716. doi: 10.1161/CIRCULATIONAHA.115.017545.
-
(2016)
Circulation
, vol.133
, pp. 706-716
-
-
Bedi, K.C.1
Snyder, N.W.2
Brandimarto, J.3
Aziz, M.4
Mesaros, C.5
Worth, A.J.6
Wang, L.L.7
Javaheri, A.8
Blair, I.A.9
Margulies, K.B.10
Rame, J.E.11
-
11
-
-
0028804087
-
Breath acetone in congestive heart failure
-
Kupari M, Lommi J, Ventilä M, Karjalainen U, Breath acetone in congestive heart failure. Am J Cardiol 1995 76 1076 1078
-
(1995)
Am J Cardiol
, vol.76
, pp. 1076-1078
-
-
Kupari, M.1
Lommi, J.2
Ventilä, M.3
Karjalainen, U.4
-
12
-
-
0030248160
-
Blood ketone bodies in congestive heart failure
-
Lommi J, Kupari M, Koskinen P, Näveri H, Leinonen H, Pulkki K, Härkönen M, Blood ketone bodies in congestive heart failure. J Am Coll Cardiol 1996 28 665 672
-
(1996)
J Am Coll Cardiol
, vol.28
, pp. 665-672
-
-
Lommi, J.1
Kupari, M.2
Koskinen, P.3
Näveri, H.4
Leinonen, H.5
Pulkki, K.6
Härkönen, M.7
-
13
-
-
84870724943
-
Urinary ketone is associated with the heart failure severity
-
Chung JH, Kim JS, Kim OY, Kang SM, Hwang GS, Shin MJ, Urinary ketone is associated with the heart failure severity. Clin Biochem 2012 45 1697 1699. doi: 10.1016/j.clinbiochem.2012.08.013.
-
(2012)
Clin Biochem
, vol.45
, pp. 1697-1699
-
-
Chung, J.H.1
Kim, J.S.2
Kim, O.Y.3
Kang, S.M.4
Hwang, G.S.5
Shin, M.J.6
-
14
-
-
84864808802
-
Exhaled acetone as a new biomaker of heart failure severity
-
Marcondes-Braga FG, Gutz IGR, Batista GL, Saldiva PHN, Ayub-Ferreira SM, Issa VS, Mangini S, Bocchi EA, Bacal F, Exhaled acetone as a new biomaker of heart failure severity. Chest 2012 142 457 466. doi: 10.1378/chest.11-2892.
-
(2012)
Chest
, vol.142
, pp. 457-466
-
-
Marcondes-Braga, F.G.1
Gutz, I.G.R.2
Batista, G.L.3
Saldiva, P.H.N.4
Ayub-Ferreira, S.M.5
Issa, V.S.6
Mangini, S.7
Bocchi, E.A.8
Bacal, F.9
-
15
-
-
84964264849
-
Exhaled acetone concentration is related to hemodynamic severity in patients with non-ischemic chronic heart failure
-
Yokokawa T, Sugano Y, Shimouchi A, Shibata A, Jinno N, Nagai T, Kanzaki H, Aiba T, Kusano K, Shirai M, Takeishi Y, Yasuda S, Ogawa H, Anzai T, Exhaled acetone concentration is related to hemodynamic severity in patients with non-ischemic chronic heart failure. Circ J 2016 80 1178 1186. doi: 10.1253/circj.CJ-16-0011.
-
(2016)
Circ J
, vol.80
, pp. 1178-1186
-
-
Yokokawa, T.1
Sugano, Y.2
Shimouchi, A.3
Shibata, A.4
Jinno, N.5
Nagai, T.6
Kanzaki, H.7
Aiba, T.8
Kusano, K.9
Shirai, M.10
Takeishi, Y.11
Yasuda, S.12
Ogawa, H.13
Anzai, T.14
-
16
-
-
0036838498
-
Dl-3-Hydroxybutyrate administration prevents myocardial damage after coronary occlusion in rat hearts
-
Zou Z, Sasaguri S, Rajesh KG, Suzuki R, dl-3-Hydroxybutyrate administration prevents myocardial damage after coronary occlusion in rat hearts. Am J Physiol Heart Circ Physiol 2002 283 H1968 H1974. doi: 10.1152/ajpheart.00250.2002.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
, pp. H1968-H1974
-
-
Zou, Z.1
Sasaguri, S.2
Rajesh, K.G.3
Suzuki, R.4
-
17
-
-
84872166360
-
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor
-
Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, Newgard CB, Farese RV Jr, de Cabo R, Ulrich S, Akassoglou K, Verdin E, Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science 2013 339 211 214. doi: 10.1126/science.1227166.
-
(2013)
Science
, vol.339
, pp. 211-214
-
-
Shimazu, T.1
Hirschey, M.D.2
Newman, J.3
He, W.4
Shirakawa, K.5
Le Moan, N.6
Grueter, C.A.7
Lim, H.8
Saunders, L.R.9
Stevens, R.D.10
Newgard, C.B.11
Farese, R.V.12
De Cabo, R.13
Ulrich, S.14
Akassoglou, K.15
Verdin, E.16
-
18
-
-
84961213631
-
The ketone body, β-hydroxybutyrate stimulates the autophagic flux and prevents neuronal death induced by glucose deprivation in cortical cultured neurons
-
Camberos-Luna L, Gerónimo-Olvera C, Montiel T, Rincon-Heredia R, Massieu L, The ketone body, β-hydroxybutyrate stimulates the autophagic flux and prevents neuronal death induced by glucose deprivation in cortical cultured neurons. Neurochem Res 2016 41 600 609. doi: 10.1007/s11064-015-1700-4.
-
(2016)
Neurochem Res
, vol.41
, pp. 600-609
-
-
Camberos-Luna, L.1
Gerónimo-Olvera, C.2
Montiel, T.3
Rincon-Heredia, R.4
Massieu, L.5
-
19
-
-
0034624968
-
D-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease
-
Kashiwaya Y, Takeshima T, Mori N, Nakashima K, Clarke K, Veech RL, D-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease. Proc Natl Acad Sci USA 2000 97 5440 5444
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5440-5444
-
-
Kashiwaya, Y.1
Takeshima, T.2
Mori, N.3
Nakashima, K.4
Clarke, K.5
Veech, R.L.6
-
20
-
-
84975775560
-
The failing heart relies on ketone bodies as a fuel
-
Aubert G, Martin OJ, Horton JL, Lai L, Vega RB, Leone TC, Koves T, Gardell SJ, Kruger M, Hoppel CL, Lewandowski ED, Crawford PA, Muoio DM, Kelly DP, The failing heart relies on ketone bodies as a fuel. Circulation 2016 133 698 705
-
(2016)
Circulation
, vol.133
, pp. 698-705
-
-
Aubert, G.1
Martin, O.J.2
Horton, J.L.3
Lai, L.4
Vega, R.B.5
Leone, T.C.6
Koves, T.7
Gardell, S.J.8
Kruger, M.9
Hoppel, C.L.10
Lewandowski, E.D.11
Crawford, P.A.12
Muoio, D.M.13
Kelly, D.P.14
-
21
-
-
84902782383
-
Oxidative post-translational modifications develop LONP1 dysfunction in pressure overload heart failure
-
Hoshino A, Okawa Y, Ariyoshi M, Kaimoto S, Uchihashi M, Fukai K, Iwai-Kanai E, Matoba S, Oxidative post-translational modifications develop LONP1 dysfunction in pressure overload heart failure. Circ Heart Fail 2014 7 500 509. doi: 10.1161/CIRCHEARTFAILURE.113.001062.
-
(2014)
Circ Heart Fail
, vol.7
, pp. 500-509
-
-
Hoshino, A.1
Okawa, Y.2
Ariyoshi, M.3
Kaimoto, S.4
Uchihashi, M.5
Fukai, K.6
Iwai-Kanai, E.7
Matoba, S.8
-
22
-
-
79954694973
-
Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure
-
Dai DF, Johnson SC, Villarin JJ, Chin MT, Nieves-Cintrón M, Chen T, Marcinek DJ, Dorn GW II, Kang YJ, Prolla TA, Santana LF, Rabinovitch PS, Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circ Res 2011 108 837 846. doi: 10.1161/CIRCRESAHA.110.232306.
-
(2011)
Circ Res
, vol.108
, pp. 837-846
-
-
Dai, D.F.1
Johnson, S.C.2
Villarin, J.J.3
Chin, M.T.4
Nieves-Cintrón, M.5
Chen, T.6
Marcinek, D.J.7
Dorn, G.W.I.I.8
Kang, Y.J.9
Prolla, T.A.10
Santana, L.F.11
Rabinovitch, P.S.12
-
23
-
-
84887454400
-
Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides
-
Dai DF, Hsieh EJ, Chen T, Menendez LG, Basisty NB, Tsai L, Beyer RP, Crispin DA, Shulman NJ, Szeto HH, Tian R, MacCoss MJ, Rabinovitch PS, Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides. Circ Heart Fail 2013 6 1067 1076. doi: 10.1161/CIRCHEARTFAILURE.113.000406.
-
(2013)
Circ Heart Fail
, vol.6
, pp. 1067-1076
-
-
Dai, D.F.1
Hsieh, E.J.2
Chen, T.3
Menendez, L.G.4
Basisty, N.B.5
Tsai, L.6
Beyer, R.P.7
Crispin, D.A.8
Shulman, N.J.9
Szeto, H.H.10
Tian, R.11
MacCoss, M.J.12
Rabinovitch, P.S.13
-
24
-
-
84555188518
-
Mitochondrial proteome remodelling in pressure overload-induced heart failure: The role of mitochondrial oxidative stress
-
Dai DF, Hsieh EJ, Liu Y, Chen T, Beyer RP, Chin MT, MacCoss MJ, Rabinovitch PS, Mitochondrial proteome remodelling in pressure overload-induced heart failure: the role of mitochondrial oxidative stress. Cardiovasc Res 2012 93 79 88. doi: 10.1093/cvr/cvr274.
-
(2012)
Cardiovasc Res
, vol.93
, pp. 79-88
-
-
Dai, D.F.1
Hsieh, E.J.2
Liu, Y.3
Chen, T.4
Beyer, R.P.5
Chin, M.T.6
MacCoss, M.J.7
Rabinovitch, P.S.8
-
25
-
-
84859642245
-
P53 promotes cardiac dysfunction in diabetic mellitus caused by excessive mitochondrial respiration-mediated reactive oxygen species generation and lipid accumulation
-
Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A, Nakaoka M, Katamura M, Okawa Y, Ariyoshi M, Mita Y, Ikeda K, Okigaki M, Adachi S, Tanaka H, Takamatsu T, Matsubara H, p53 promotes cardiac dysfunction in diabetic mellitus caused by excessive mitochondrial respiration-mediated reactive oxygen species generation and lipid accumulation. Circ Heart Fail 2012 5 106 115. doi: 10.1161/CIRCHEARTFAILURE.111.961565.
-
(2012)
Circ Heart Fail
, vol.5
, pp. 106-115
-
-
Nakamura, H.1
Matoba, S.2
Iwai-Kanai, E.3
Kimata, M.4
Hoshino, A.5
Nakaoka, M.6
Katamura, M.7
Okawa, Y.8
Ariyoshi, M.9
Mita, Y.10
Ikeda, K.11
Okigaki, M.12
Adachi, S.13
Tanaka, H.14
Takamatsu, T.15
Matsubara, H.16
-
26
-
-
84970022005
-
β-Hydroxybutyrate elevation as a compensatory response against oxidative stress in cardiomyocytes
-
Nagao M, Toh R, Irino Y, Mori T, Nakajima H, Hara T, Honjo T, Satomi-Kobayashi S, Shinke T, Tanaka H, Ishida T, Hirata K, β-Hydroxybutyrate elevation as a compensatory response against oxidative stress in cardiomyocytes. Biochem Biophys Res Commun 2016 475 322 328. doi: 10.1016/j.bbrc.2016.05.097.
-
(2016)
Biochem Biophys Res Commun
, vol.475
, pp. 322-328
-
-
Nagao, M.1
Toh, R.2
Irino, Y.3
Mori, T.4
Nakajima, H.5
Hara, T.6
Honjo, T.7
Satomi-Kobayashi, S.8
Shinke, T.9
Tanaka, H.10
Ishida, T.11
Hirata, K.12
-
27
-
-
34247559154
-
Ketone bodies alter dinitrophenol-induced glucose uptake through AMPK inhibition and oxidative stress generation in adult cardiomyocytes
-
Pelletier A, Coderre L, Ketone bodies alter dinitrophenol-induced glucose uptake through AMPK inhibition and oxidative stress generation in adult cardiomyocytes. Am J Physiol Endocrinol Metab 2007 292 E1325 E1332. doi: 10.1152/ajpendo.00186.2006.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
, pp. E1325-E1332
-
-
Pelletier, A.1
Coderre, L.2
-
28
-
-
84908143721
-
Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling
-
Schugar RC, Moll AR, André d'Avignon D, Weinheimer CJ, Kovacs A, Crawford PA, Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling. Mol Metab 2014 3 754 769. doi: 10.1016/j.molmet.2014.07.010.
-
(2014)
Mol Metab
, vol.3
, pp. 754-769
-
-
Schugar, R.C.1
Moll, A.R.2
André D'Avignon, D.3
Weinheimer, C.J.4
Kovacs, A.5
Crawford, P.A.6
-
29
-
-
77955301740
-
Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment
-
Wentz AE, d'Avignon DA, Weber ML, Cotter DG, Doherty JM, Kerns R, Nagarajan R, Reddy N, Sambandam N, Crawford PA, Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment. J Biol Chem 2010 285 24447 24456. doi: 10.1074/jbc.M110.100651.
-
(2010)
J Biol Chem
, vol.285
, pp. 24447-24456
-
-
Wentz, A.E.1
D'Avignon, D.A.2
Weber, M.L.3
Cotter, D.G.4
Doherty, J.M.5
Kerns, R.6
Nagarajan, R.7
Reddy, N.8
Sambandam, N.9
Crawford, P.A.10
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