The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer

Genome Medicine

Volumn 9, Issue 1, 2017, Pages

  Widschwendter, Martin ^a   Zikan, Michal ^b   Wahl, Benjamin ^c   Lempiäinen, Harri ^d   Paprotka, Tobias ^c   Evans, Iona ^a   Jones, Allison ^a   Ghazali, Shohreh ^a   Reisel, Daniel ^a   Eichner, Johannes ^d   Rujan, Tamas ^d   Yang, Zhen ^e   Teschendorff, Andrew E ^a,e   Ryan, Andy ^a   Cibula, David ^b   Menon, Usha ^a   Wittenberger, Timo ^d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b CHARLES UNIVERSITY   (Czech Republic)

^c GATC Biotech AG   (Germany)

^d GENEDATA AG   (Switzerland)

^e MAX PLANCK INSTITUTE   (Germany)

Author keywords

Cell free DNA; DNA methylation; Early diagnosis; Ovarian cancer; Personalized treatment; Screening; Serum DNA

Indexed keywords

BISULFITE; CA 125 ANTIGEN; CELL FREE NUCLEIC ACID; TUMOR MARKER;

ADULT; ARTICLE; BLOOD SAMPLING; CANCER SCREENING; CASE CONTROL STUDY; CELL FREE SYSTEM; CIRCULATING TUMOR CELL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DNA CONTAMINATION; DNA ISOLATION; DNA METHYLATION; EARLY CANCER DIAGNOSIS; ENDOMETRIOSIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIQUID BIOPSY; MALE; NEOADJUVANT CHEMOTHERAPY; OVARY CANCER; PELVIS; PERSONALIZED MEDICINE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; UNITED KINGDOM COLLABORATIVE TRIAL OF OVARIAN CANCER SCREENING; AGED; BLOOD; DNA SEQUENCE; EVALUATION STUDY; GENETICS; MIDDLE AGED; OVARY TUMOR; PROCEDURES; RANDOMIZATION; STANDARDS;

ADULT; AGED; BIOMARKERS, TUMOR; CELL-FREE NUCLEIC ACIDS; DNA METHYLATION; FEMALE; HUMANS; MIDDLE AGED; OVARIAN NEOPLASMS; RANDOM ALLOCATION; SEQUENCE ANALYSIS, DNA;

EID: 85038919999     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/s13073-017-0500-7     Document Type: Article

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