메뉴 건너뛰기




Volumn 8, Issue DEC, 2017, Pages

ATP modifies the proteome of extracellular vesicles released by microglia and influences their action on astrocytes

Author keywords

Astrocyte activation; ATP; Extracellular vesicles; Microglia; Proteomics

Indexed keywords

ADENOSINE TRIPHOSPHATE; PROTEOME;

EID: 85038239508     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2017.00910     Document Type: Article
Times cited : (117)

References (63)
  • 2
    • 84857998516 scopus 로고    scopus 로고
    • Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism
    • Antonucci, F., Turola, E., Riganti, L., Caleo, M., Gabrielli, M., Perrotta, C., et al. (2012). Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism. EMBO J. 31, 1231-1240. doi: 10.1038/emboj.2011.489
    • (2012) EMBO J , vol.31 , pp. 1231-1240
    • Antonucci, F.1    Turola, E.2    Riganti, L.3    Caleo, M.4    Gabrielli, M.5    Perrotta, C.6
  • 3
    • 0028800295 scopus 로고
    • Thrombospondin-4, an extracellular matrix protein expressed in the developing and adult nervous system promotes neurite outgrowth
    • Arber, S., and Caroni, P. (1995). Thrombospondin-4, an extracellular matrix protein expressed in the developing and adult nervous system promotes neurite outgrowth. J. Cell Biol. 131, 1083-1094. doi: 10.1083/jcb.131.4.1083
    • (1995) J. Cell Biol , vol.131 , pp. 1083-1094
    • Arber, S.1    Caroni, P.2
  • 4
    • 0017404160 scopus 로고
    • A simple method for the preparation of homogeneous phospholipid vesicles
    • Barenholz, Y., Gibbes, D., Litman, B. J., Goll, J., Thompson, T. E., and Carlson, R. D. (1977). A simple method for the preparation of homogeneous phospholipid vesicles. Biochemistry 16, 2806-2810. doi: 10.1021/bi00631a035
    • (1977) Biochemistry , vol.16 , pp. 2806-2810
    • Barenholz, Y.1    Gibbes, D.2    Litman, B.J.3    Goll, J.4    Thompson, T.E.5    Carlson, R.D.6
  • 5
    • 17844385044 scopus 로고    scopus 로고
    • Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia
    • Bianco, F., Fumagalli, M., Pravettoni, E., D'ambrosi, N., Volonte, C., Matteoli, M., et al. (2005a). Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia. Brain Res. Brain Res. Rev. 48, 144-156. doi: 10.1016/j.brainresrev.2004.12.004
    • (2005) Brain Res. Brain Res. Rev , vol.48 , pp. 144-156
    • Bianco, F.1    Fumagalli, M.2    Pravettoni, E.3    D'ambrosi, N.4    Volonte, C.5    Matteoli, M.6
  • 6
    • 18944380607 scopus 로고    scopus 로고
    • Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia
    • Bianco, F., Pravettoni, E., Colombo, A., Schenk, U., Moller, T., Matteoli, M., et al. (2005b). Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia. J. Immunol. 174, 7268-7277
    • (2005) J. Immunol , vol.174 , pp. 7268-7277
    • Bianco, F.1    Pravettoni, E.2    Colombo, A.3    Schenk, U.4    Moller, T.5    Matteoli, M.6
  • 7
    • 67349114201 scopus 로고    scopus 로고
    • Acid sphingomyelinase activity triggers microparticle release from glial cells
    • Bianco, F., Perrotta, C., Novellino, L., Francolini, M., Riganti, L., Menna, E., et al. (2009). Acid sphingomyelinase activity triggers microparticle release from glial cells. EMBO J. 28, 1043-1054. doi: 10.1038/emboj.2009.45
    • (2009) EMBO J , vol.28 , pp. 1043-1054
    • Bianco, F.1    Perrotta, C.2    Novellino, L.3    Francolini, M.4    Riganti, L.5    Menna, E.6
  • 8
    • 79953016863 scopus 로고    scopus 로고
    • Fast and reversible stimulation of astrocytic glycolysis by K+ and a delayed and persistent effect of glutamate
    • Bittner, C. X., Valdebenito, R., Ruminot, I., Loaiza, A., Larenas, V., Sotelo-Hitschfeld, T., et al. (2011). Fast and reversible stimulation of astrocytic glycolysis by K+ and a delayed and persistent effect of glutamate. J. Neurosci. 31, 4709-4713. doi: 10.1523/JNEUROSCI.5311-10.2011
    • (2011) J. Neurosci , vol.31 , pp. 4709-4713
    • Bittner, C.X.1    Valdebenito, R.2    Ruminot, I.3    Loaiza, A.4    Larenas, V.5    Sotelo-Hitschfeld, T.6
  • 9
    • 84924548953 scopus 로고    scopus 로고
    • Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation
    • [Epub ahead of print]
    • Burguillos, M. A., Svensson, M., Schulte, T., Boza-Serrano, A., Garcia-Quintanilla, A., Kavanagh, E., et al. (2015). Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation. Cell Rep. doi: 10.1016/j.celrep.2015.02.012 [Epub ahead of print]
    • (2015) Cell Rep
    • Burguillos, M.A.1    Svensson, M.2    Schulte, T.3    Boza-Serrano, A.4    Garcia-Quintanilla, A.5    Kavanagh, E.6
  • 10
    • 84893745524 scopus 로고    scopus 로고
    • Identification of a unique TGF-beta-dependent molecular and functional signature in microglia
    • Butovsky, O., Jedrychowski, M. P., Moore, C. S., Cialic, R., Lanser, A. J., Gabriely, G., et al. (2014). Identification of a unique TGF-beta-dependent molecular and functional signature in microglia. Nat. Neurosci. 17, 131-143. doi: 10.1038/nn.3599
    • (2014) Nat. Neurosci , vol.17 , pp. 131-143
    • Butovsky, O.1    Jedrychowski, M.P.2    Moore, C.S.3    Cialic, R.4    Lanser, A.J.5    Gabriely, G.6
  • 11
    • 84992386887 scopus 로고    scopus 로고
    • Sall1 is a transcriptional regulator defining microglia identity and function
    • Buttgereit, A., Lelios, I., Yu, X., Vrohlings, M., Krakoski, N. R., Gautier, E. L., et al. (2016). Sall1 is a transcriptional regulator defining microglia identity and function. Nat. Immunol. 17, 1397-1406. doi: 10.1038/ni.3585
    • (2016) Nat. Immunol , vol.17 , pp. 1397-1406
    • Buttgereit, A.1    Lelios, I.2    Yu, X.3    Vrohlings, M.4    Krakoski, N.R.5    Gautier, E.L.6
  • 12
    • 84978817828 scopus 로고    scopus 로고
    • Developmental apoptosis mediates entry and positioning of microglia in the zebrafish brain
    • Casano, A. M., Albert, M., and Peri, F. (2016). Developmental apoptosis mediates entry and positioning of microglia in the zebrafish brain. Cell Rep. 16, 897-906. doi: 10.1016/j.celrep.2016.06.033
    • (2016) Cell Rep , vol.16 , pp. 897-906
    • Casano, A.M.1    Albert, M.2    Peri, F.3
  • 13
    • 84923238571 scopus 로고    scopus 로고
    • Microglia: multitasking specialists of the brain
    • Casano, A. M., and Peri, F. (2015). Microglia: multitasking specialists of the brain. Dev. Cell 32, 469-477. doi: 10.1016/j.devcel.2015.01.018
    • (2015) Dev. Cell , vol.32 , pp. 469-477
    • Casano, A.M.1    Peri, F.2
  • 14
    • 84929506373 scopus 로고    scopus 로고
    • Ectosomes and exosomes: shedding the confusion between extracellular vesicles
    • Cocucci, E., and Meldolesi, J. (2015). Ectosomes and exosomes: shedding the confusion between extracellular vesicles. Trends Cell Biol. 25, 364-372. doi: 10.1016/j.tcb.2015.01.004
    • (2015) Trends Cell Biol , vol.25 , pp. 364-372
    • Cocucci, E.1    Meldolesi, J.2
  • 15
    • 84861487658 scopus 로고    scopus 로고
    • New insights regarding the regulation of chemotaxis by nucleotides, adenosine, and their receptors
    • Corriden, R., and Insel, P. A. (2012). New insights regarding the regulation of chemotaxis by nucleotides, adenosine, and their receptors. Purinergic Signal. 8, 587-598. doi: 10.1007/s11302-012-9311-x
    • (2012) Purinergic Signal , vol.8 , pp. 587-598
    • Corriden, R.1    Insel, P.A.2
  • 16
    • 85021312383 scopus 로고    scopus 로고
    • Knowledge and attitudes toward vaccination: a survey of Serbian students
    • Cvjetkovic, S. J., Jeremic, V. L., and Tiosavljevic, D. V. (2017). Knowledge and attitudes toward vaccination: a survey of Serbian students. J. Infect. Public Health 10, 649-656. doi: 10.1016/j.jiph.2017.05.008
    • (2017) J. Infect. Public Health , vol.10 , pp. 649-656
    • Cvjetkovic, S.J.1    Jeremic, V.L.2    Tiosavljevic, D.V.3
  • 17
    • 77954613183 scopus 로고    scopus 로고
    • CFTR inhibition provokes an inflammatory response associated with an imbalance of the annexin A1 pathway
    • Dalli, J., Rosignoli, G., Hayhoe, R. P., Edelman, A., and Perretti, M. (2010). CFTR inhibition provokes an inflammatory response associated with an imbalance of the annexin A1 pathway. Am. J. Pathol. 177, 176-186. doi: 10.2353/ajpath.2010.091149
    • (2010) Am. J. Pathol , vol.177 , pp. 176-186
    • Dalli, J.1    Rosignoli, G.2    Hayhoe, R.P.3    Edelman, A.4    Perretti, M.5
  • 18
    • 19544374896 scopus 로고    scopus 로고
    • Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation
    • Damazo, A. S., Yona, S., D'acquisto, F., Flower, R. J., Oliani, S. M., and Perretti, M. (2005). Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation. Am. J. Pathol. 166, 1607-1617. doi: 10.1016/S0002-9440(10)62471-6
    • (2005) Am. J. Pathol , vol.166 , pp. 1607-1617
    • Damazo, A.S.1    Yona, S.2    D'acquisto, F.3    Flower, R.J.4    Oliani, S.M.5    Perretti, M.6
  • 19
    • 22244464662 scopus 로고    scopus 로고
    • ATP mediates rapid microglial response to local brain injury in vivo
    • Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., et al. (2005). ATP mediates rapid microglial response to local brain injury in vivo. Nat. Neurosci. 8, 752-758. doi: 10.1038/nn1472
    • (2005) Nat. Neurosci , vol.8 , pp. 752-758
    • Davalos, D.1    Grutzendler, J.2    Yang, G.3    Kim, J.V.4    Zuo, Y.5    Jung, S.6
  • 20
    • 84960155925 scopus 로고    scopus 로고
    • Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process
    • de Torre-Minguela, C., Barbera-Cremades, M., Gomez, A. I., Martin-Sanchez, F., and Pelegrin, P. (2016). Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process. Sci. Rep. 6:22586. doi: 10.1038/srep22586
    • (2016) Sci. Rep , vol.6 , pp. 22586
    • de Torre-Minguela, C.1    Barbera-Cremades, M.2    Gomez, A.I.3    Martin-Sanchez, F.4    Pelegrin, P.5
  • 21
    • 23944509766 scopus 로고    scopus 로고
    • Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation
    • Del Conde, I., Shrimpton, C. N., Thiagarajan, P., and Lopez, J. A. (2005). Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood 106, 1604-1611. doi: 10.1182/blood-2004-03-1095
    • (2005) Blood , vol.106 , pp. 1604-1611
    • Del Conde, I.1    Shrimpton, C.N.2    Thiagarajan, P.3    Lopez, J.A.4
  • 22
    • 84959016597 scopus 로고    scopus 로고
    • Persistent activation of microglia and NADPH oxidase [corrected] drive hippocampal dysfunction in experimental multiple sclerosis
    • Di Filippo, M., De Iure, A., Giampa, C., Chiasserini, D., Tozzi, A., Orvietani, P. L., et al. (2016). Persistent activation of microglia and NADPH oxidase [corrected] drive hippocampal dysfunction in experimental multiple sclerosis. Sci. Rep. 6:20926. doi: 10.1038/srep20926
    • (2016) Sci. Rep , vol.6 , pp. 20926
    • Di Filippo, M.1    De Iure, A.2    Giampa, C.3    Chiasserini, D.4    Tozzi, A.5    Orvietani, P.L.6
  • 23
    • 33947700320 scopus 로고    scopus 로고
    • Purinergic signalling in the immune system A brief update
    • Di Virgilio, F. (2007). Purinergic signalling in the immune system. A brief update. Purinergic Signal. 3, 1-3. doi: 10.1007/s11302-006-9048-5
    • (2007) Purinergic Signal , vol.3 , pp. 1-3
    • Di Virgilio, F.1
  • 24
    • 84875995596 scopus 로고    scopus 로고
    • Neurotransmitter signaling in the pathophysiology of microglia
    • Domercq, M., Vazquez-Villoldo, N., and Matute, C. (2013). Neurotransmitter signaling in the pathophysiology of microglia. Front. Cell Neurosci. 7:49. doi: 10.3389/fncel.2013.00049
    • (2013) Front. Cell Neurosci , vol.7 , pp. 49
    • Domercq, M.1    Vazquez-Villoldo, N.2    Matute, C.3
  • 25
    • 84862781810 scopus 로고    scopus 로고
    • Microglial migration mediated by ATP-induced ATP release from lysosomes
    • Dou, Y., Wu, H. J., Li, H. Q., Qin, S., Wang, Y. E., Li, J., et al. (2012). Microglial migration mediated by ATP-induced ATP release from lysosomes. Cell Res. 22, 1022-1033. doi: 10.1038/cr.2012.10
    • (2012) Cell Res , vol.22 , pp. 1022-1033
    • Dou, Y.1    Wu, H.J.2    Li, H.Q.3    Qin, S.4    Wang, Y.E.5    Li, J.6
  • 26
    • 70350368006 scopus 로고    scopus 로고
    • Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis
    • Eroglu, C., Allen, N. J., Susman, M. W., O'rourke, N. A., Park, C. Y., Ozkan, E., et al. (2009). Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis. Cell 139, 380-392. doi: 10.1016/j.cell.2009.09.025
    • (2009) Cell , vol.139 , pp. 380-392
    • Eroglu, C.1    Allen, N.J.2    Susman, M.W.3    O'rourke, N.A.4    Park, C.Y.5    Ozkan, E.6
  • 27
    • 33745760093 scopus 로고    scopus 로고
    • Purinergic signaling and microglia
    • Farber, K., and Kettenmann, H. (2006). Purinergic signaling and microglia. Pflugers. Arch. 452, 615-621. doi: 10.1007/s11302-006-9048-5
    • (2006) Pflugers. Arch , vol.452 , pp. 615-621
    • Farber, K.1    Kettenmann, H.2
  • 28
    • 84906097556 scopus 로고    scopus 로고
    • Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation
    • Frohlich, D., Kuo, W. P., Fruhbeis, C., Sun, J. J., Zehendner, C. M., Luhmann, H. J., et al. (2014). Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation. Philos. Trans. R. Soc. Lond. B Biol. Sci. 369:20130510. doi: 10.1098/rstb.2013.0510
    • (2014) Philos. Trans. R. Soc. Lond. B Biol. Sci , vol.369
    • Frohlich, D.1    Kuo, W.P.2    Fruhbeis, C.3    Sun, J.J.4    Zehendner, C.M.5    Luhmann, H.J.6
  • 29
    • 84880950361 scopus 로고    scopus 로고
    • Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication
    • Fruhbeis, C., Frohlich, D., Kuo, W. P., Amphornrat, J., Thilemann, S., Saab, A. S., et al. (2013). Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLOS Biol. 11:e1001604. doi: 10.1371/journal.pbio.1001604
    • (2013) PLOS Biol , vol.11
    • Fruhbeis, C.1    Frohlich, D.2    Kuo, W.P.3    Amphornrat, J.4    Thilemann, S.5    Saab, A.S.6
  • 30
    • 84949623094 scopus 로고    scopus 로고
    • Active endocannabinoids are secreted on extracellular membrane vesicles
    • Gabrielli, M., Battista, N., Riganti, L., Prada, I., Antonucci, F., Cantone, L., et al. (2015). Active endocannabinoids are secreted on extracellular membrane vesicles. EMBO Rep. 16, 213-220. doi: 10.15252/embr.201439668
    • (2015) EMBO Rep , vol.16 , pp. 213-220
    • Gabrielli, M.1    Battista, N.2    Riganti, L.3    Prada, I.4    Antonucci, F.5    Cantone, L.6
  • 31
    • 58249118710 scopus 로고    scopus 로고
    • Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation
    • Gastardelo, T. S., Damazo, A. S., Dalli, J., Flower, R. J., Perretti, M., and Oliani, S. M. (2009). Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation. Am. J. Pathol. 174, 177-183. doi: 10.2353/ajpath.2009.080342
    • (2009) Am. J. Pathol , vol.174 , pp. 177-183
    • Gastardelo, T.S.1    Damazo, A.S.2    Dalli, J.3    Flower, R.J.4    Perretti, M.5    Oliani, S.M.6
  • 32
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adult microglia derive from primitive macrophages
    • Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., et al. (2010). Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 330, 841-845. doi: 10.1126/science.1194637
    • (2010) Science , vol.330 , pp. 841-845
    • Ginhoux, F.1    Greter, M.2    Leboeuf, M.3    Nandi, S.4    See, P.5    Gokhan, S.6
  • 33
    • 84878087706 scopus 로고    scopus 로고
    • Anti-inflammatory mechanisms of the annexin A1 protein and its mimetic peptide Ac2-26 in models of ocular inflammation in vivo and in vitro
    • Girol, A. P., Mimura, K. K., Drewes, C. C., Bolonheis, S. M., Solito, E., Farsky, S. H., et al. (2013). Anti-inflammatory mechanisms of the annexin A1 protein and its mimetic peptide Ac2-26 in models of ocular inflammation in vivo and in vitro. J. Immunol. 190, 5689-5701. doi: 10.4049/jimmunol.1202030
    • (2013) J. Immunol , vol.190 , pp. 5689-5701
    • Girol, A.P.1    Mimura, K.K.2    Drewes, C.C.3    Bolonheis, S.M.4    Solito, E.5    Farsky, S.H.6
  • 34
    • 84959110290 scopus 로고    scopus 로고
    • Microglial brain region-dependent diversity and selective regional sensitivities to aging
    • Grabert, K., Michoel, T., Karavolos, M. H., Clohisey, S., Baillie, J. K., Stevens, M. P., et al. (2016). Microglial brain region-dependent diversity and selective regional sensitivities to aging. Nat. Neurosci. 19, 504-516. doi: 10.1038/nn.4222
    • (2016) Nat. Neurosci , vol.19 , pp. 504-516
    • Grabert, K.1    Michoel, T.2    Karavolos, M.H.3    Clohisey, S.4    Baillie, J.K.5    Stevens, M.P.6
  • 35
    • 68849086814 scopus 로고    scopus 로고
    • Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation
    • Gu, B. J., Rathsam, C., Stokes, L., Mcgeachie, A. B., and Wiley, J. S. (2009). Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation. Am. J. Physiol. Cell Physiol. 297, C430-C439. doi: 10.1152/ajpcell.00079.2009
    • (2009) Am. J. Physiol. Cell Physiol , vol.297 , pp. C430-C439
    • Gu, B.J.1    Rathsam, C.2    Stokes, L.3    Mcgeachie, A.B.4    Wiley, J.S.5
  • 37
    • 0035869474 scopus 로고    scopus 로고
    • Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors
    • Honda, S., Sasaki, Y., Ohsawa, K., Imai, Y., Nakamura, Y., Inoue, K., et al. (2001). Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J. Neurosci. 21, 1975-1982
    • (2001) J. Neurosci , vol.21 , pp. 1975-1982
    • Honda, S.1    Sasaki, Y.2    Ohsawa, K.3    Imai, Y.4    Nakamura, Y.5    Inoue, K.6
  • 38
    • 84869881760 scopus 로고    scopus 로고
    • Wnt3a induces exosome secretion from primary cultured rat microglia
    • Hooper, C., Sainz-Fuertes, R., Lynham, S., Hye, A., Killick, R., Warley, A., et al. (2012). Wnt3a induces exosome secretion from primary cultured rat microglia. BMC Neurosci. 13:144. doi: 10.1186/1471-2202-13-144
    • (2012) BMC Neurosci , vol.13 , pp. 144
    • Hooper, C.1    Sainz-Fuertes, R.2    Lynham, S.3    Hye, A.4    Killick, R.5    Warley, A.6
  • 39
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da, W., Sherman, B. T., and Lempicki, R. A. (2009). Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57. doi: 10.1038/nprot.2008.211
    • (2009) Nat. Protoc , vol.4 , pp. 44-57
    • da Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 40
    • 85027873149 scopus 로고    scopus 로고
    • Extracellular vesicles are independent metabolic units with asparaginase activity
    • Iraci, N., Gaude, E., Leonardi, T., Costa, A. S. H., Cossetti, C., Peruzzotti-Jametti, L., et al. (2017). Extracellular vesicles are independent metabolic units with asparaginase activity. Nat. Chem. Biol. 13, 951-955. doi: 10.1038/nchembio.2422
    • (2017) Nat. Chem. Biol , vol.13 , pp. 951-955
    • Iraci, N.1    Gaude, E.2    Leonardi, T.3    Costa, A.S.H.4    Cossetti, C.5    Peruzzotti-Jametti, L.6
  • 41
    • 0035890154 scopus 로고    scopus 로고
    • Proteomic and functional evidence for a P2X7 receptor signalling complex
    • Kim, M., Jiang, L. H., Wilson, H. L., North, R. A., and Surprenant, A. (2001). Proteomic and functional evidence for a P2X7 receptor signalling complex. EMBO J. 20, 6347-6358. doi: 10.1093/emboj/20.22.6347
    • (2001) EMBO J , vol.20 , pp. 6347-6358
    • Kim, M.1    Jiang, L.H.2    Wilson, H.L.3    North, R.A.4    Surprenant, A.5
  • 42
  • 43
    • 84963969178 scopus 로고    scopus 로고
    • Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation
    • Lui, H., Zhang, J., Makinson, S. R., Cahill, M. K., Kelley, K. W., Huang, H. Y., et al. (2016). Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation. Cell 165, 921-935. doi: 10.1016/j.cell.2016.04.001
    • (2016) Cell , vol.165 , pp. 921-935
    • Lui, H.1    Zhang, J.2    Makinson, S.R.3    Cahill, M.K.4    Kelley, K.W.5    Huang, H.Y.6
  • 45
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • Nimmerjahn, A., Kirchhoff, F., and Helmchen, F. (2005). Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308, 1314-1318. doi: 10.1126/science.1110647
    • (2005) Science , vol.308 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 46
    • 77952573195 scopus 로고    scopus 로고
    • P2Y12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP
    • Ohsawa, K., Irino, Y., Sanagi, T., Nakamura, Y., Suzuki, E., Inoue, K., et al. (2010). P2Y12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP. Glia 58, 790-801. doi: 10.1002/glia.20963
    • (2010) Glia , vol.58 , pp. 790-801
    • Ohsawa, K.1    Irino, Y.2    Sanagi, T.3    Nakamura, Y.4    Suzuki, E.5    Inoue, K.6
  • 47
    • 58149233871 scopus 로고    scopus 로고
    • Fluctuation of annexin-A1 positive mast cells in chronic granulomatous inflammation
    • Oliani, S. M., Ciocca, G. A., Pimentel, T. A., Damazo, A. S., Gibbs, L., and Perretti, M. (2008). Fluctuation of annexin-A1 positive mast cells in chronic granulomatous inflammation. Inflamm. Res. 57, 450-456. doi: 10.1007/s00011-008-7222-7
    • (2008) Inflamm. Res , vol.57 , pp. 450-456
    • Oliani, S.M.1    Ciocca, G.A.2    Pimentel, T.A.3    Damazo, A.S.4    Gibbs, L.5    Perretti, M.6
  • 48
    • 80052633284 scopus 로고    scopus 로고
    • Synaptic pruning by microglia is necessary for normal brain development
    • Paolicelli, R. C., Bolasco, G., Pagani, F., Maggi, L., Scianni, M., Panzanelli, P., et al. (2011). Synaptic pruning by microglia is necessary for normal brain development. Science 333, 1456-1458. doi: 10.1126/science.1202529
    • (2011) Science , vol.333 , pp. 1456-1458
    • Paolicelli, R.C.1    Bolasco, G.2    Pagani, F.3    Maggi, L.4    Scianni, M.5    Panzanelli, P.6
  • 49
    • 34247353273 scopus 로고    scopus 로고
    • Stimulation of P2 receptors causes release of IL-1beta-loaded microvesicles from human dendritic cells
    • Pizzirani, C., Ferrari, D., Chiozzi, P., Adinolfi, E., Sandona, D., Savaglio, E., et al. (2007). Stimulation of P2 receptors causes release of IL-1beta-loaded microvesicles from human dendritic cells. Blood 109, 3856-3864. doi: 10.1182/blood-2005-06-031377
    • (2007) Blood , vol.109 , pp. 3856-3864
    • Pizzirani, C.1    Ferrari, D.2    Chiozzi, P.3    Adinolfi, E.4    Sandona, D.5    Savaglio, E.6
  • 50
    • 34848843543 scopus 로고    scopus 로고
    • Neurotransmitter receptors on microglia
    • Pocock, J. M., and Kettenmann, H. (2007). Neurotransmitter receptors on microglia. Trends Neurosci. 30, 527-535. doi: 10.1016/j.tins.2007.07.007
    • (2007) Trends Neurosci , vol.30 , pp. 527-535
    • Pocock, J.M.1    Kettenmann, H.2
  • 51
    • 26844505013 scopus 로고    scopus 로고
    • Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC
    • Potolicchio, I., Chitta, S., Xu, X., Fonseca, D., Crisi, G., Horejsi, V., et al. (2005). Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC. J. Immunol. 175, 4935-4947. doi: 10.4049/jimmunol.175.8.4935
    • (2005) J. Immunol , vol.175 , pp. 4935-4947
    • Potolicchio, I.1    Chitta, S.2    Xu, X.3    Fonseca, D.4    Crisi, G.5    Horejsi, V.6
  • 52
    • 84954348643 scopus 로고    scopus 로고
    • A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers
    • Prada, I., Amin, L., Furlan, R., Legname, G., Verderio, C., and Cojoc, D. (2016). A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers. Biotechniques 60, 35-41. doi: 10.2144/000114371
    • (2016) Biotechniques , vol.60 , pp. 35-41
    • Prada, I.1    Amin, L.2    Furlan, R.3    Legname, G.4    Verderio, C.5    Cojoc, D.6
  • 53
    • 84879586923 scopus 로고    scopus 로고
    • Classical and unconventional pathways of vesicular release in microglia
    • Prada, I., Furlan, R., Matteoli, M., and Verderio, C. (2013). Classical and unconventional pathways of vesicular release in microglia. Glia 61, 1003-1017. doi: 10.1002/glia.22497
    • (2013) Glia , vol.61 , pp. 1003-1017
    • Prada, I.1    Furlan, R.2    Matteoli, M.3    Verderio, C.4
  • 54
    • 85027931163 scopus 로고    scopus 로고
    • Altered microglial phagocytosis in GPR34-deficient mice
    • Preissler, J., Grosche, A., Lede, V., Le Duc, D., Krugel, K., Matyash, V., et al. (2015). Altered microglial phagocytosis in GPR34-deficient mice. Glia 63, 206-215. doi: 10.1002/glia.22744
    • (2015) Glia , vol.63 , pp. 206-215
    • Preissler, J.1    Grosche, A.2    Lede, V.3    Le Duc, D.4    Krugel, K.5    Matyash, V.6
  • 55
    • 0032970384 scopus 로고    scopus 로고
    • Murine microglial cells produce and respond to interleukin-18
    • Prinz, M., and Hanisch, U. K. (1999). Murine microglial cells produce and respond to interleukin-18. J. Neurochem. 72, 2215-2218. doi: 10.1046/j.1471-4159.1999.0722215.x
    • (1999) J. Neurochem , vol.72 , pp. 2215-2218
    • Prinz, M.1    Hanisch, U.K.2
  • 57
    • 84862154879 scopus 로고    scopus 로고
    • Long-range Ca2+ waves transmit brain-damage signals to microglia
    • Sieger, D., Moritz, C., Ziegenhals, T., Prykhozhij, S., and Peri, F. (2012). Long-range Ca2+ waves transmit brain-damage signals to microglia. Dev. Cell 22, 1138-1148. doi: 10.1016/j.devcel.2012.04.012
    • (2012) Dev. Cell , vol.22 , pp. 1138-1148
    • Sieger, D.1    Moritz, C.2    Ziegenhals, T.3    Prykhozhij, S.4    Peri, F.5
  • 58
    • 84860338445 scopus 로고    scopus 로고
    • The complement system: an unexpected role in synaptic pruning during development and disease
    • Stephan, A. H., Barres, B. A., and Stevens, B. (2012). The complement system: an unexpected role in synaptic pruning during development and disease. Annu. Rev. Neurosci. 35, 369-389. doi: 10.1146/annurev-neuro-061010-113810
    • (2012) Annu. Rev. Neurosci , vol.35 , pp. 369-389
    • Stephan, A.H.1    Barres, B.A.2    Stevens, B.3
  • 59
    • 36849076770 scopus 로고    scopus 로고
    • The classical complement cascade mediates CNS synapse elimination
    • Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., et al. (2007). The classical complement cascade mediates CNS synapse elimination. Cell 131, 1164-1178. doi: 10.1016/j.cell.2007.10.036
    • (2007) Cell , vol.131 , pp. 1164-1178
    • Stevens, B.1    Allen, N.J.2    Vazquez, L.E.3    Howell, G.R.4    Christopherson, K.S.5    Nouri, N.6
  • 60
    • 78649853114 scopus 로고    scopus 로고
    • Activation of macrophages by P2X7-induced microvesicles from myeloid cells is mediated by phospholipids and is partially dependent on TLR4
    • Thomas, L. M., and Salter, R. D. (2010). Activation of macrophages by P2X7-induced microvesicles from myeloid cells is mediated by phospholipids and is partially dependent on TLR4. J. Immunol. 185, 3740-3749. doi: 10.4049/jimmunol.1001231
    • (2010) J. Immunol , vol.185 , pp. 3740-3749
    • Thomas, L.M.1    Salter, R.D.2
  • 61
    • 84866425004 scopus 로고    scopus 로고
    • Microglial microvesicle secretion and intercellular signaling
    • Turola, E., Furlan, R., Bianco, F., Matteoli, M., and Verderio, C. (2012). Microglial microvesicle secretion and intercellular signaling. Front. Physiol. 3:149. doi: 10.3389/fphys.2012.00149
    • (2012) Front. Physiol , vol.3 , pp. 149
    • Turola, E.1    Furlan, R.2    Bianco, F.3    Matteoli, M.4    Verderio, C.5
  • 62
    • 84866343704 scopus 로고    scopus 로고
    • Myeloid microvesicles are a marker and therapeutic target for neuroinflammation
    • Verderio, C., Muzio, L., Turola, E., Bergami, A., Novellino, L., Ruffini, F., et al. (2012). Myeloid microvesicles are a marker and therapeutic target for neuroinflammation. Ann. Neurol. 72, 610-624. doi: 10.1002/ana.23627
    • (2012) Ann. Neurol , vol.72 , pp. 610-624
    • Verderio, C.1    Muzio, L.2    Turola, E.3    Bergami, A.4    Novellino, L.5    Ruffini, F.6
  • 63
    • 84946607022 scopus 로고    scopus 로고
    • Annexin A2 binds to endosomes and negatively regulates TLR4-triggered inflammatory responses via the TRAM-TRIF pathway
    • Zhang, S., Yu, M., Guo, Q., Li, R., Li, G., Tan, S., et al. (2015). Annexin A2 binds to endosomes and negatively regulates TLR4-triggered inflammatory responses via the TRAM-TRIF pathway. Sci. Rep. 5:15859. doi: 10.1038/srep15859
    • (2015) Sci. Rep , vol.5 , pp. 15859
    • Zhang, S.1    Yu, M.2    Guo, Q.3    Li, R.4    Li, G.5    Tan, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.