Polyphenol-rich ethyl acetate fraction isolated from Molineria latifolia ameliorates insulin resistance in experimental diabetic rats via IRS1/AKT activation

Biomedicine and Pharmacotherapy

Volumn 98, Issue , 2018, Pages 125-133

  Ooi, Der Jiun ^a   Adamu, Hadiza Altine ^a   Imam, Mustapha Umar ^a,b   Ithnin, Hairuszah ^a   Ismail, Maznah ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^b ZHENGZHOU UNIVERSITY   (China)

Author keywords

Ethyl acetate fraction; Insulin resistance; Insulin signaling; IRS1 AKT activation; Type 2 diabetes mellitus

Indexed keywords

ACETIC ACID ETHYL ESTER; ADIPOCYTOKINE; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; LIPID; NICOTINAMIDE; POLYPHENOL; PROTEIN KINASE B; STREPTOZOCIN; ACETIC ACID; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, RAT; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; GENE EXPRESSION; GLUCOSE TOLERANCE; HYPOXIDACEAE; IN VIVO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SIGNALING; LIPID DIET; LIVER TISSUE; MALE; MOLINERIA LATIFOLIA; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RHIZOME; SKELETAL MUSCLE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TRANSCRIPTION REGULATION; ANIMAL; CHEMISTRY; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; LIVER; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ACETATES; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; HYPOXIDACEAE; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; LIVER; MALE; PHOSPHORYLATION; PLANT EXTRACTS; POLYPHENOLS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STREPTOZOCIN;

EID: 85038020982     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2017.12.002     Document Type: Article

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