Imipenem–Relebactam and Meropenem–Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations

Drugs

Volumn 78, Issue 1, 2018, Pages 65-98

  Zhanel, George G ^a,c   Lawrence, Courtney K ^b   Adam, Heather ^a,d   Schweizer, Frank ^a,b   Zelenitsky, Sheryl ^b   Zhanel, Michael ^a   Lagacé Wiens, Philippe R S ^a,d   Walkty, Andrew ^a,c,d   Denisuik, Andrew ^a   Golden, Alyssa ^a   Gin, Alfred S ^a,b,c   Hoban, Daryl J ^a,d   Lynch, Joseph P ^e   Karlowsky, James A ^a,d  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c HEALTH SCIENCES CENTRE   (Canada)

^d Diagnostic Services of Manitoba Inc   (Canada)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMIPENEM; MEROPENEM; RELEBACTAM; VABORBACTAM; ANTIINFECTIVE AGENT; AZABICYCLO DERIVATIVE; BETA LACTAMASE INHIBITOR; BORONIC ACID DERIVATIVE; MK-7655; SINGLE HETEROCYCLIC RINGS; THIENAMYCIN DERIVATIVE;

ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; CHEMISTRY; COMBINATION DRUG THERAPY; DRUG MECHANISM; HUMAN; MEDICAL MICROBIOLOGY; NONHUMAN; PHARMACODYNAMIC PARAMETERS; PHARMACOKINETIC PARAMETERS; REVIEW; SIDE EFFECT; ABDOMINAL INFECTION; ANIMAL; CHEMICAL STRUCTURE; DRUG COMBINATION; DRUG EFFECT; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-BACTERIAL AGENTS; AZABICYCLO COMPOUNDS; BETA-LACTAMASE INHIBITORS; BORONIC ACIDS; DRUG COMBINATIONS; DRUG RESISTANCE, BACTERIAL; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; IMIPENEM; INTRAABDOMINAL INFECTIONS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; THIENAMYCINS;

EID: 85037681739     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.1007/s40265-017-0851-9     Document Type: Review

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