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Volumn 49, Issue 1, 2015, Pages 86-98

β-Lactam/β-Lactamase Inhibitor Combinations: From Then to Now

Author keywords

avibactam; bacterial resistance; carbapenemase; clavulanate; MK 7655; relebactam; RPX7009; sulbactam; tazobactam; lactamase; lactamase inhibitor

Indexed keywords

7 OXO N (4 PIPERIDINYL) 1,6 DIAZABICYCLO[3.2.1]OCTANE 2 CARBOXAMIDE; AMOXICILLIN; AVIBACTAM; AVIBACTAM PLUS CEFTAZIDIME; AZTREONAM; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; BETA LACTAMASE INHIBITOR; BIAPENEM; CARBAPENEMASE; CEFTAROLINE; CEFTOLOZANE PLUS TAZOBACTAM; CLAVULANIC ACID; IMIPENEM; PIPERACILLIN PLUS TAZOBACTAM; RELEBACTAM; RPX 7009; SULBACTAM; SULTAMICILLIN; TAZOBACTAM; TICARCILLIN; UNCLASSIFIED DRUG; AMPC BETA-LACTAMASES; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAM;

EID: 84919629764     PISSN: 10600280     EISSN: 15426270     Source Type: Journal    
DOI: 10.1177/1060028014556652     Document Type: Review
Times cited : (118)

References (112)
  • 1
    • 25144512582 scopus 로고    scopus 로고
    • Beta-lactam antibiotic resistance: a current structural perspective
    • Wilke M,Lovering A,Strynadka N.Beta-lactam antibiotic resistance: a current structural perspective.Curr Opin Microbiol. 2005;8:525-533
    • (2005) Curr Opin Microbiol , vol.8 , pp. 525-533
    • Wilke, M.1    Lovering, A.2    Strynadka, N.3
  • 2
    • 79958818528 scopus 로고    scopus 로고
    • Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention
    • Gupta N,Limbag B,Patel J,Kallen A.Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention.Clin Infect Dis. 2011;53:60-67
    • (2011) Clin Infect Dis , vol.53 , pp. 60-67
    • Gupta, N.1    Limbag, B.2    Patel, J.3    Kallen, A.4
  • 3
    • 40549126250 scopus 로고    scopus 로고
    • Predictors of carbapenem-resistant Klebsiella pneumonia acquisition among hospitalized adults and effect of acquisition on mortality
    • Schwaber MJ,Klarfeld-Lidji S,Navon-Venezia S,Schwartz D,Leavitt A,Carmeli Y.Predictors of carbapenem-resistant Klebsiella pneumonia acquisition among hospitalized adults and effect of acquisition on mortality.Antimicrob Agents Chemother. 2008;52:1028-1033
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1028-1033
    • Schwaber, M.J.1    Klarfeld-Lidji, S.2    Navon-Venezia, S.3    Schwartz, D.4    Leavitt, A.5    Carmeli, Y.6
  • 4
    • 84866072596 scopus 로고    scopus 로고
    • Predictors of mortality in bloodstream infections caused by Klebsiella pneumonia carbapenemase-producing K. pneumoniae: importance of combination therapy
    • ,,, et al.. ;:-
    • Tumbarello M,Viale P,Viscoli C, et al.Predictors of mortality in bloodstream infections caused by Klebsiella pneumonia carbapenemase-producing K. pneumoniae: importance of combination therapy.Clin Infect Dis. 2012;55:943-950
    • (2012) Clin Infect Dis , vol.55 , pp. 943-950
    • Tumbarello, M.1    Viale, P.2    Viscoli, C.3
  • 5
    • 0028883511 scopus 로고
    • Beta-lactamases in laboratory and clinical resistance
    • Livermore DM.Beta-lactamases in laboratory and clinical resistance.Clin Microbiol Rev. 1995;8:557-584
    • (1995) Clin Microbiol Rev , vol.8 , pp. 557-584
    • Livermore, D.M.1
  • 6
    • 0027479143 scopus 로고
    • Determinants of the activity of beta-lactamase inhibitor combinations
    • Livermore DM.Determinants of the activity of beta-lactamase inhibitor combinations.J Antimicrob Chemother. 1993;31:9-21
    • (1993) J Antimicrob Chemother , vol.31 , pp. 9-21
    • Livermore, D.M.1
  • 7
    • 0023686284 scopus 로고
    • Beta-lactamase inhibitors from laboratory to clinic
    • Bush K.Beta-lactamase inhibitors from laboratory to clinic.Clin Microbiol Rev. 1988;1:109-123
    • (1988) Clin Microbiol Rev , vol.1 , pp. 109-123
    • Bush, K.1
  • 8
    • 0031029659 scopus 로고    scopus 로고
    • Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics
    • Medeiros A.Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics.Clin Infect Dis. 1997;24:S19-S45
    • (1997) Clin Infect Dis , vol.24 , pp. S19-S45
    • Medeiros, A.1
  • 9
    • 0029073602 scopus 로고
    • Extended-spectrum plasmid-mediated beta lactamases
    • Sirot D.Extended-spectrum plasmid-mediated beta lactamases.J Antimicrob Chemother. 1995;36:19-34
    • (1995) J Antimicrob Chemother , vol.36 , pp. 19-34
    • Sirot, D.1
  • 11
    • 0033823040 scopus 로고    scopus 로고
    • Beta-lactamase inhibitor combinations with extended-spectrum penicillins: factors influencing antibacterial activity against Enterobacteriaceae and Pseudomonas aeruginosa
    • Lister P.Beta-lactamase inhibitor combinations with extended-spectrum penicillins: factors influencing antibacterial activity against Enterobacteriaceae and Pseudomonas aeruginosa.Pharmacotherapy. 2000;20:213S-218S
    • (2000) Pharmacotherapy , vol.20 , pp. 213S-218S
    • Lister, P.1
  • 12
    • 0023583815 scopus 로고
    • Clinical significance of beta-lactamase induction and stable depression in Gram-negative rods
    • Livermore DM.Clinical significance of beta-lactamase induction and stable depression in Gram-negative rods.Eur J Clin Microbiol. 1987;6:439-445
    • (1987) Eur J Clin Microbiol , vol.6 , pp. 439-445
    • Livermore, D.M.1
  • 13
    • 33646837531 scopus 로고    scopus 로고
    • Resistance in Gram negative bacteria: Enterobacteriaceae
    • Paterson D.Resistance in Gram negative bacteria: Enterobacteriaceae.Am J Med. 2006;119:S20-S28
    • (2006) Am J Med , vol.119 , pp. S20-S28
    • Paterson, D.1
  • 14
    • 84888615316 scopus 로고    scopus 로고
    • Class D beta-lactamases: a reappraisal after five decades
    • Leonard D,Bonomo K,Powers R.Class D beta-lactamases: a reappraisal after five decades.Acc Chem Res. 2013;46:2407-2415
    • (2013) Acc Chem Res , vol.46 , pp. 2407-2415
    • Leonard, D.1    Bonomo, K.2    Powers, R.3
  • 15
    • 0029071785 scopus 로고
    • A functional classification scheme for beta-lactamases and its correlation with molecular structure
    • Bush K,Jacoby GA,Medeiros A.A functional classification scheme for beta-lactamases and its correlation with molecular structure.Antimicrob Agents Chemother. 1995;39:1211-1233
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 1211-1233
    • Bush, K.1    Jacoby, G.A.2    Medeiros, A.3
  • 16
    • 77149165713 scopus 로고    scopus 로고
    • Updated functional classification of beta-lactamases
    • Bush K,Jacoby GA.Updated functional classification of beta-lactamases.Antimicrob Agents Chemother. 2010;54:969-976
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 969-976
    • Bush, K.1    Jacoby, G.A.2
  • 17
    • 0035311003 scopus 로고    scopus 로고
    • New beta-lactamases in Gram-negative bacteria: diversity and impact on the selection of antimicrobial therapy
    • Bush K.New beta-lactamases in Gram-negative bacteria: diversity and impact on the selection of antimicrobial therapy.Clin Infect Dis. 2001;32:1085-1089
    • (2001) Clin Infect Dis , vol.32 , pp. 1085-1089
    • Bush, K.1
  • 18
    • 0023037794 scopus 로고
    • Epidemiology of antibiotic resistance in Staphylococcus aureus
    • Lacey R,Kruczenk S.Epidemiology of antibiotic resistance in Staphylococcus aureus.J Antimicrob Chemother. 1986;18:207-214
    • (1986) J Antimicrob Chemother , vol.18 , pp. 207-214
    • Lacey, R.1    Kruczenk, S.2
  • 19
    • 0031747315 scopus 로고    scopus 로고
    • Beta-lactamase mediated resistance and opportunities for its control
    • Livermore D.Beta-lactamase mediated resistance and opportunities for its control.J Antimicrob Chemother. 1998;41:25-41
    • (1998) J Antimicrob Chemother , vol.41 , pp. 25-41
    • Livermore, D.1
  • 20
    • 34547422759 scopus 로고    scopus 로고
    • Carbapenemases: the versatile beta-lactamases
    • Queenan AM,Bush K.Carbapenemases: the versatile beta-lactamases.Clin Microbiol Rev. 2007;20:440-458
    • (2007) Clin Microbiol Rev , vol.20 , pp. 440-458
    • Queenan, A.M.1    Bush, K.2
  • 21
    • 51849123182 scopus 로고    scopus 로고
    • Zn and antibiotic resistance: metallo beta-lactamases and their synthetic analogues
    • Tamilselvi A,Mugesh G.Zn and antibiotic resistance: metallo beta-lactamases and their synthetic analogues.J Biol Inorg Chem. 2008;13:1039-1053
    • (2008) J Biol Inorg Chem , vol.13 , pp. 1039-1053
    • Tamilselvi, A.1    Mugesh, G.2
  • 22
    • 78049300941 scopus 로고    scopus 로고
    • Efficacy of calcium-EDTA as an inhibitor for metallo beta-lactamases in a mouse model of Pseudomonas aeruginosa pneumonia
    • ,,, et al.. ;:-
    • Aoki N,Ishii Y,Tateda K, et al.Efficacy of calcium-EDTA as an inhibitor for metallo beta-lactamases in a mouse model of Pseudomonas aeruginosa pneumonia.Antimicrob Agents Chemother. 2010;54:4582-4588
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 4582-4588
    • Aoki, N.1    Ishii, Y.2    Tateda, K.3
  • 23
    • 59649115459 scopus 로고    scopus 로고
    • AmpC beta-lactamases
    • Jacoby G.AmpC beta-lactamases.Clin Microbiol Rev. 2009;22:161
    • (2009) Clin Microbiol Rev , vol.22 , pp. 161
    • Jacoby, G.1
  • 24
    • 0031800337 scopus 로고    scopus 로고
    • Important and emerging beta-lactamase-mediated resistances in hospital-based pathogens: the AmpC enzymes
    • Jones R.Important and emerging beta-lactamase-mediated resistances in hospital-based pathogens: the AmpC enzymes.Diagn Microbiol Infect Dis. 1998;31:461-466
    • (1998) Diagn Microbiol Infect Dis , vol.31 , pp. 461-466
    • Jones, R.1
  • 25
    • 0027193905 scopus 로고
    • A comparative study of class D beta-lactamases
    • ,,, et al.. ;:-
    • Ledent P,Raquet K,Joris B, et al.A comparative study of class D beta-lactamases.Biochem J. 1993;292:555-562
    • (1993) Biochem J , vol.292 , pp. 555-562
    • Ledent, P.1    Raquet, K.2    Joris, B.3
  • 26
    • 73849084148 scopus 로고    scopus 로고
    • Diversity, epidemiology, and genetics of class D beta-lactamases
    • Poirel L,Naas T,Nordmann P.Diversity, epidemiology, and genetics of class D beta-lactamases.Antimicrob Agents Chemother. 2010;54:24-38
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 24-38
    • Poirel, L.1    Naas, T.2    Nordmann, P.3
  • 27
    • 0031928706 scopus 로고    scopus 로고
    • Molecular characterization of OXA-20, a novel, Class D beta-lactamase, and its integrin from Pseudomonas aeruginosa
    • ,,, et al.. ;:-
    • Naas T,Sougakoff W,Casetta A, et al.Molecular characterization of OXA-20, a novel, Class D beta-lactamase, and its integrin from Pseudomonas aeruginosa.Antimicrob Agents Chemother. 1998;42:2074-2083
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 2074-2083
    • Naas, T.1    Sougakoff, W.2    Casetta, A.3
  • 28
    • 0017074284 scopus 로고
    • Naturally occurring beta-lactamase inhibitors with antibacterial activity
    • ,,, et al.. ;:-
    • Brown AG,Butterworth D,Cole M, et al.Naturally occurring beta-lactamase inhibitors with antibacterial activity.J Antibiot (Tokyo). 1976;29:668-669
    • (1976) J Antibiot (Tokyo) , vol.29 , pp. 668-669
    • Brown, A.G.1    Butterworth, D.2    Cole, M.3
  • 29
    • 77951060664 scopus 로고    scopus 로고
    • Current challenges in antimicrobial chemotherapy: a focus on beta-lactamase inhibition
    • ,,, et al.. ;:-
    • Bebrone C,Lassaux P,Vercheval L, et al.Current challenges in antimicrobial chemotherapy: a focus on beta-lactamase inhibition.Drugs. 2010;70:651-679
    • (2010) Drugs , vol.70 , pp. 651-679
    • Bebrone, C.1    Lassaux, P.2    Vercheval, L.3
  • 30
    • 74249108028 scopus 로고    scopus 로고
    • Three decades of beta-lactamase inhibitors
    • Drawz S,Bonomo R.Three decades of beta-lactamase inhibitors.Clin Microbiol Rev. 2010;23:160-201
    • (2010) Clin Microbiol Rev , vol.23 , pp. 160-201
    • Drawz, S.1    Bonomo, R.2
  • 31
    • 9644268224 scopus 로고    scopus 로고
    • Pharmacodynamic profiling of piperacillin in the presence of tazobactam in patients through the use of population pharmacokinetic models and Monte Carlo simulation
    • Lodise T,Lomaestro B,Rodvold K,Danzinger L,Drusano G.Pharmacodynamic profiling of piperacillin in the presence of tazobactam in patients through the use of population pharmacokinetic models and Monte Carlo simulation.Antimicrob Agents Chemother. 2004;48:4718-4724
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 4718-4724
    • Lodise, T.1    Lomaestro, B.2    Rodvold, K.3    Danzinger, L.4    Drusano, G.5
  • 32
    • 0028985646 scopus 로고
    • Interaction of sulbactam, clavulanic acid, and tazobactam with penicillin-binding proteins of imipenem-resistant and imipenem-susceptible Acinetobacter baumannii
    • Urban C,Go E,Mariano N,Rahal JJ.Interaction of sulbactam, clavulanic acid, and tazobactam with penicillin-binding proteins of imipenem-resistant and imipenem-susceptible Acinetobacter baumannii.FEMS Microbiol Lett. 1995;125:193-197
    • (1995) FEMS Microbiol Lett , vol.125 , pp. 193-197
    • Urban, C.1    Go, E.2    Mariano, N.3    Rahal, J.J.4
  • 33
    • 84911003547 scopus 로고    scopus 로고
    • Combination antibiotic treatment versus monotherapy for multidrug-resistant, extensively-drug resistant, and pandrug-resistant Acinetobacter infections: a systematic review
    • Poulikakos P,Tansarli G,Falagas M.Combination antibiotic treatment versus monotherapy for multidrug-resistant, extensively-drug resistant, and pandrug-resistant Acinetobacter infections: a systematic review.Euro J Clin Microbiol Infect Dis. 2014;33:1675-1685
    • (2014) Euro J Clin Microbiol Infect Dis , vol.33 , pp. 1675-1685
    • Poulikakos, P.1    Tansarli, G.2    Falagas, M.3
  • 34
    • 0024421625 scopus 로고
    • Comparative in vitro and in vivo activities of piperacillin combined with the beta-lactamase inhibitors tazobactam, clavulanic acid, and sulbactam
    • Kuck N,Jacobus N,Petersen P,Weiss W,Testa R.Comparative in vitro and in vivo activities of piperacillin combined with the beta-lactamase inhibitors tazobactam, clavulanic acid, and sulbactam.Antimicrob Agents Chemother. 1989;33:1964-1969
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 1964-1969
    • Kuck, N.1    Jacobus, N.2    Petersen, P.3    Weiss, W.4    Testa, R.5
  • 35
    • 41449096190 scopus 로고    scopus 로고
    • Why clinically used tazobactam and sulbactam are poor inhibitors of OXA-10 beta lactamases: Raman crystallographic evidence
    • ,,, et al.. ;:-
    • Totir MA,Cha J,Ishiwata A, et al.Why clinically used tazobactam and sulbactam are poor inhibitors of OXA-10 beta lactamases: Raman crystallographic evidence.Biochemistry. 2008;47:4094-4101
    • (2008) Biochemistry , vol.47 , pp. 4094-4101
    • Totir, M.A.1    Cha, J.2    Ishiwata, A.3
  • 36
    • 0028219728 scopus 로고
    • Comparative activities of clavulanic acid, sulbactam, and tazobactam against clinically important beta-lactamases
    • Payne D,Cramp R,Winstanley D,Knowles D.Comparative activities of clavulanic acid, sulbactam, and tazobactam against clinically important beta-lactamases.Antimicrob Agents Chemother. 1994;38:767-772
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 767-772
    • Payne, D.1    Cramp, R.2    Winstanley, D.3    Knowles, D.4
  • 37
    • 84873673370 scopus 로고    scopus 로고
    • Comparative evaluation of the in-vitro activity of six beta-lactam/beta-lactamase inhibitor combinations against Gram negative bacilli
    • Sood S.Comparative evaluation of the in-vitro activity of six beta-lactam/beta-lactamase inhibitor combinations against Gram negative bacilli.J Clin Diagn Res. 2013;7:224-228
    • (2013) J Clin Diagn Res , vol.7 , pp. 224-228
    • Sood, S.1
  • 38
    • 0032445066 scopus 로고    scopus 로고
    • Mechanisms of beta-lactam resistance amongst Pseudomonas aeruginosa isolated in an Italian survey
    • Bonfiglio G,Laksai Y,Franchino L,Amicosante G,Nicoletti G.Mechanisms of beta-lactam resistance amongst Pseudomonas aeruginosa isolated in an Italian survey.J Antimicrob Chemother. 1998;42:697-702
    • (1998) J Antimicrob Chemother , vol.42 , pp. 697-702
    • Bonfiglio, G.1    Laksai, Y.2    Franchino, L.3    Amicosante, G.4    Nicoletti, G.5
  • 39
    • 84875175772 scopus 로고    scopus 로고
    • In vivo activities of Ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended-spectrum-lactamases, in the thighs of neutropenic mice
    • Craig WA,Andes DR.In vivo activities of Ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended-spectrum-lactamases, in the thighs of neutropenic mice.Antimicrob Agents Chemother. 2013;57:1577-1582
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 1577-1582
    • Craig, W.A.1    Andes, D.R.2
  • 40
    • 84919640981 scopus 로고    scopus 로고
    • Efficacy and safety of ceftolozane/tazobactam versus levofloxacin in the treatment of complicated urinary tract infections (cUTI)/pyelonephritis in hospitalized adults: results from the phase 3 ASPECT-cUTI trial (abstract eP449)
    • ,,, et al.; Barcelona, Spain
    • Wagenlehner F,Umeh O,Huntington J, et al.Efficacy and safety of ceftolozane/tazobactam versus levofloxacin in the treatment of complicated urinary tract infections (cUTI)/pyelonephritis in hospitalized adults: results from the phase 3 ASPECT-cUTI trial (abstract eP449).Paper presented at: European Congress of Clinical Microbiology and Infectious Diseases (ECCMID); Barcelona, Spain;.
    • Paper presented at: European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
    • Wagenlehner, F.1    Umeh, O.2    Huntington, J.3
  • 41
    • 84908327025 scopus 로고    scopus 로고
    • Efficacy and safety of ceftolozane/tazobactam versus meropenem in the treatment of complicated intra-abdominal infections (cIAI) in hospitalized adults: results from the phase 3 ASPECT-cIAI trial (abstract P0266-a)
    • ,,, et al.; Barcelona, Spain
    • Eckmann C,Hershberger E,Miller B, et al.Efficacy and safety of ceftolozane/tazobactam versus meropenem in the treatment of complicated intra-abdominal infections (cIAI) in hospitalized adults: results from the phase 3 ASPECT-cIAI trial (abstract P0266-a).Paper presented at: European Congress of Clinical Microbiology and Infectious Diseases (ECCMID); Barcelona, Spain;.
    • Paper presented at: European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
    • Eckmann, C.1    Hershberger, E.2    Miller, B.3
  • 42
    • 84919640979 scopus 로고    scopus 로고
    • Cubist Pharmaceuticals. Safety and efficacy study of ceftolozane/tazobactam to treat ventilated nosocomial pneumonia (ASPECT-NP). NLM Identifier: NCT02070757. Accessed August 11, 2014
    • Cubist Pharmaceuticals. Safety and efficacy study of ceftolozane/tazobactam to treat ventilated nosocomial pneumonia (ASPECT-NP). http://clinicaltrials.gov/ct2/show/NCT02070757. NLM Identifier: NCT02070757. Accessed August 11, 2014.
  • 43
    • 81155162497 scopus 로고    scopus 로고
    • Diazabicyclooctanes (DBOs): a potent new class of non-beta-lactam beta-lactamase inhibitors
    • Coleman K.Diazabicyclooctanes (DBOs): a potent new class of non-beta-lactam beta-lactamase inhibitors.Curr Opin Microbiol. 2011;14:550-555
    • (2011) Curr Opin Microbiol , vol.14 , pp. 550-555
    • Coleman, K.1
  • 44
    • 84872844727 scopus 로고    scopus 로고
    • New beta-lactam/beta-lactamase inhibitor combinations in clinical development
    • Shales D.New beta-lactam/beta-lactamase inhibitor combinations in clinical development.Ann N Y Acad Sci. 2013;1277:105-114
    • (2013) Ann N Y Acad Sci , vol.1277 , pp. 105-114
    • Shales, D.1
  • 45
    • 84877842576 scopus 로고    scopus 로고
    • Structural insight into potent broad-spectrum inhibition with reversible recyclization mechanism: avibactam in complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-lactamases
    • ,,, et al.. ;:-
    • Lahiri SD,Mangani S,Durand-Reville T, et al.Structural insight into potent broad-spectrum inhibition with reversible recyclization mechanism: avibactam in complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-lactamases.Antimicrob Agents Chemother. 2013;57:2496-2505
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 2496-2505
    • Lahiri, S.D.1    Mangani, S.2    Durand-Reville, T.3
  • 46
    • 78649683457 scopus 로고    scopus 로고
    • Mechanistic studies of the inactivation of TEM-1 and P99 by NXL104, a novel non-beta-lactam beta-lactamase inhibitor
    • ,,, et al.. ;:-
    • Stachyra T,Péchereau MC,Bruneau JM, et al.Mechanistic studies of the inactivation of TEM-1 and P99 by NXL104, a novel non-beta-lactam beta-lactamase inhibitor.Antimicrob Agents Chemother. 2010;54:5132-5138
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 5132-5138
    • Stachyra, T.1    Péchereau, M.C.2    Bruneau, J.M.3
  • 47
    • 84878278251 scopus 로고    scopus 로고
    • 10x’20 Progress: development of new drugs active against Gram-negative bacilli: an update from the Infectious Diseases Society of America
    • ,,, et al.. ;:-
    • Boucher H,Talbot G,Benjamin D, et al.10x’20 Progress: development of new drugs active against Gram-negative bacilli: an update from the Infectious Diseases Society of America.Clin Infect Dis. 2013;56:1685-1694
    • (2013) Clin Infect Dis , vol.56 , pp. 1685-1694
    • Boucher, H.1    Talbot, G.2    Benjamin, D.3
  • 48
    • 84884764949 scopus 로고    scopus 로고
    • Kinetics of avibactam inhibition against class A, C and D beta-lactamases
    • ,,, et al.. ;:-
    • Ehmann D,Jahic H,Ross P, et al.Kinetics of avibactam inhibition against class A, C and D beta-lactamases.J Biol Chem. 2013;288:27960-27971
    • (2013) J Biol Chem , vol.288 , pp. 27960-27971
    • Ehmann, D.1    Jahic, H.2    Ross, P.3
  • 49
    • 67650718178 scopus 로고    scopus 로고
    • In vitro activity of the beta-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases
    • ,,, et al.. ;:-
    • Stachyra T,Levasseur P,Péchereau MC, et al.In vitro activity of the beta-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases.Antimicrob Agents Chemother. 2009;64:326-329
    • (2009) Antimicrob Agents Chemother , vol.64 , pp. 326-329
    • Stachyra, T.1    Levasseur, P.2    Péchereau, M.C.3
  • 50
    • 84863905057 scopus 로고    scopus 로고
    • Avibactam is a covalent, reversible, non-beta-lactam beta-lactamase inhibitor
    • ,,, et al.. ;:-
    • Ehmann D,Jahic H,Ross PL, et al.Avibactam is a covalent, reversible, non-beta-lactam beta-lactamase inhibitor.Proc Natl Acad Sci U S A. 2012;109:11663-11668
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 11663-11668
    • Ehmann, D.1    Jahic, H.2    Ross, P.L.3
  • 51
    • 84919640978 scopus 로고    scopus 로고
    • AztraZeneca. Ceftazidime-avibactam for the treatment of infections due to ceftazidime resistant pathogens. Accessed January 2, 2014
    • AztraZeneca. Ceftazidime-avibactam for the treatment of infections due to ceftazidime resistant pathogens. http://clinicaltrials.gov/ct2/show/NCT01644643?term=avibactam&rank=6. Accessed January 2, 2014.
  • 52
    • 84919640977 scopus 로고    scopus 로고
    • AztraZeneca. A study comparing ceftazidime-avibactam versus meropenem in hospitalized adults with nosocomial pneumonia. Accessed January 27, 2014
    • AztraZeneca. A study comparing ceftazidime-avibactam versus meropenem in hospitalized adults with nosocomial pneumonia. http://clinicaltrials.gov/ct2/show/NCT01808092?term=avibactam&rank=11. Accessed January 27, 2014.
  • 53
    • 84919640976 scopus 로고    scopus 로고
    • Cerexa, Inc. Comparative study of coadministered ceftaroline foxamil and NXL 104 vs. intravenous doripenem in adult subjects with complicated urinary tract infections. Accessed January 2, 2014
    • Cerexa, Inc. Comparative study of coadministered ceftaroline foxamil and NXL 104 vs. intravenous doripenem in adult subjects with complicated urinary tract infections. http://clinicaltrials.gov/ct2/show/NCT01281462?term=avibactam&rank=5. Accessed January 2, 2014.
  • 54
    • 84919640975 scopus 로고    scopus 로고
    • AstraZeneca. To investigate the safety and tolerability of aztreonam-avibactam (ATM-AVI). Accessed August 11, 2014
    • AstraZeneca. To investigate the safety and tolerability of aztreonam-avibactam (ATM-AVI). http://clinicaltrials.gov/ct2/show/NCT01689207?term=aztreonam+avibactam&rank=1. Accessed August 11, 2014.
  • 55
    • 84857173233 scopus 로고    scopus 로고
    • In vitro antibacterial activity of the ceftazidime-avibactam (NXL104) combination against Pseudomonas aeruginosa clinical isolates
    • ,,, et al.. ;:-
    • Levasseur P,Girard AM,Claudon M, et al.In vitro antibacterial activity of the ceftazidime-avibactam (NXL104) combination against Pseudomonas aeruginosa clinical isolates.Antimicrob Agents Chemother. 2012;56:1606-1608
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 1606-1608
    • Levasseur, P.1    Girard, A.M.2    Claudon, M.3
  • 56
    • 84869237392 scopus 로고    scopus 로고
    • Comparative in vitro and in vivo efficacies of human simulated doses of ceftazidime and ceftazidime-avibactam against Pseudomonas aeruginosa
    • ,,, et al.. ;:-
    • Crandon J,Shuck V,Banevicius M, et al.Comparative in vitro and in vivo efficacies of human simulated doses of ceftazidime and ceftazidime-avibactam against Pseudomonas aeruginosa.Antimicrob Agents Chemother. 2012;56:6137-6146
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 6137-6146
    • Crandon, J.1    Shuck, V.2    Banevicius, M.3
  • 57
    • 79956326529 scopus 로고    scopus 로고
    • In vitro activity of ceftazidime combined with nxl104 versus Pseudomonas aeruginosa isolates obtained from patients in Canadian hospitals
    • Walkty A,DeCorby M,Lagace-Wiens PRS,Karlowsky J,Hoban D,Zhanel G.In vitro activity of ceftazidime combined with nxl104 versus Pseudomonas aeruginosa isolates obtained from patients in Canadian hospitals.Antimicrob Agents Chemother. 2011;55:2992-2994
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 2992-2994
    • Walkty, A.1    DeCorby, M.2    Lagace-Wiens, P.R.S.3    Karlowsky, J.4    Hoban, D.5    Zhanel, G.6
  • 58
    • 77957862993 scopus 로고    scopus 로고
    • In vitro activity of ceftazidime1NXL104 against Pseudomonas aeruginosa and other non-fermenters
    • Mushtaq S,Warner M,Livermore D.In vitro activity of ceftazidime1NXL104 against Pseudomonas aeruginosa and other non-fermenters.J Antimicrob Chemother. 2010;65:2376-2381
    • (2010) J Antimicrob Chemother , vol.65 , pp. 2376-2381
    • Mushtaq, S.1    Warner, M.2    Livermore, D.3
  • 59
    • 70449124604 scopus 로고    scopus 로고
    • Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms
    • Lister P,Wolter D,Hanson N.Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms.Clin Microbiol Rev. 2009;22:582-610
    • (2009) Clin Microbiol Rev , vol.22 , pp. 582-610
    • Lister, P.1    Wolter, D.2    Hanson, N.3
  • 60
    • 82955187694 scopus 로고    scopus 로고
    • In vitro activity of avibactam (NXL104) in combination with beta-lactams against Gram-negative bacteria, including OXA-48 beta-lactamase-producing Klebsiella pneumoniae
    • Atkas Z,Kayacan C,Oncul O.In vitro activity of avibactam (NXL104) in combination with beta-lactams against Gram-negative bacteria, including OXA-48 beta-lactamase-producing Klebsiella pneumoniae.Int J Antimicrob Agents. 2012;39:86-89
    • (2012) Int J Antimicrob Agents , vol.39 , pp. 86-89
    • Atkas, Z.1    Kayacan, C.2    Oncul, O.3
  • 61
    • 78650664486 scopus 로고    scopus 로고
    • Evaluation of ceftazidime and NXL 104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae
    • Endimiani A,Hujer K,Hujer A,Pulse M,Weiss W,Bonomo R.Evaluation of ceftazidime and NXL 104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae.Antimicrob Agents Chemother. 2011;55:82-85
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 82-85
    • Endimiani, A.1    Hujer, K.2    Hujer, A.3    Pulse, M.4    Weiss, W.5    Bonomo, R.6
  • 62
    • 84860436685 scopus 로고    scopus 로고
    • Anti-anaerobic activity of a new beta-lactamase inhibitor NXL104 in combination with beta-lactams and metronidazole
    • Dubreuil LJ,Mahieux S,Neut C,Miossec C,Pace J.Anti-anaerobic activity of a new beta-lactamase inhibitor NXL104 in combination with beta-lactams and metronidazole.Int J Antimicrob Agents. 2012;39:500-504
    • (2012) Int J Antimicrob Agents , vol.39 , pp. 500-504
    • Dubreuil, L.J.1    Mahieux, S.2    Neut, C.3    Miossec, C.4    Pace, J.5
  • 63
    • 84877123198 scopus 로고    scopus 로고
    • Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole in the treatment of intra-abdominal infections in hospitalized adults: results of a randomized, double-blind, phase II trial
    • Lucasti C,Popescu I,Ramesh M,Lipka J,Sable C.Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole in the treatment of intra-abdominal infections in hospitalized adults: results of a randomized, double-blind, phase II trial.J Antimicrob Chemother. 2013;68:1183-1192
    • (2013) J Antimicrob Chemother , vol.68 , pp. 1183-1192
    • Lucasti, C.1    Popescu, I.2    Ramesh, M.3    Lipka, J.4    Sable, C.5
  • 64
    • 84870399321 scopus 로고    scopus 로고
    • Efficacy and safety of ceftazidime-avibactam versus imipenem-cilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: results of a prospective, investigator-blinded, randomized study
    • ,,, et al.. ;:-
    • Vazquez JA,Gonzalez Patzan LD,Stricklin D, et al.Efficacy and safety of ceftazidime-avibactam versus imipenem-cilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: results of a prospective, investigator-blinded, randomized study.Curr Med Res Opin. 2012;28:1921-1931
    • (2012) Curr Med Res Opin , vol.28 , pp. 1921-1931
    • Vazquez, J.A.1    Gonzalez Patzan, L.D.2    Stricklin, D.3
  • 65
    • 84919640974 scopus 로고    scopus 로고
    • AstraZeneca. Comparative study of NXL104/ceftazidime versus comparator in adults with complicated urinary tract infections. Accessed August 18, 2011
    • AstraZeneca. Comparative study of NXL104/ceftazidime versus comparator in adults with complicated urinary tract infections. http://clinicaltrials.gov/ct2/show/NCT00690378?term=avibactam&rank=15. Accessed August 18, 2011.
  • 66
    • 84919640973 scopus 로고    scopus 로고
    • Ceftazidime/avibactam trials. Accessed February 10, 2014
    • Ceftazidime/avibactam trials. http://clinicaltrials.gov/ct2/show/NCT01726023?term=ceftazidime%2Favibactam&rank=4. Accessed February 10, 2014.
  • 67
    • 78649452602 scopus 로고    scopus 로고
    • Ceftaroline fosamil: a novel broad-spectrum cephalosporin with expanded anti-Gram-positive activity
    • Biek D,Critchley IA,Riccobene TA,Thye DA.Ceftaroline fosamil: a novel broad-spectrum cephalosporin with expanded anti-Gram-positive activity.J Antimicrob Chemother. 2010;65:iv9-iv16
    • (2010) J Antimicrob Chemother , vol.65 , pp. iv9-iv16
    • Biek, D.1    Critchley, I.A.2    Riccobene, T.A.3    Thye, D.A.4
  • 68
    • 79956304769 scopus 로고    scopus 로고
    • In vitro activity of ceftaroline against Gram-positive and Gram-negative pathogens isolated from patients in Canadian hospitals in 2009
    • Karlowsky J,Adam H,Decorby M,Lagace-Wiens P,Hoban D,Zhanel GG.In vitro activity of ceftaroline against Gram-positive and Gram-negative pathogens isolated from patients in Canadian hospitals in 2009.Antimicrob Agents Chemother. 2011;55:2837-2846
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 2837-2846
    • Karlowsky, J.1    Adam, H.2    Decorby, M.3    Lagace-Wiens, P.4    Hoban, D.5    Zhanel, G.G.6
  • 69
    • 84875140013 scopus 로고    scopus 로고
    • Antimicrobial activity of ceftaroline-avibactam tested against clinical isolates collected from US medical centers in 2010-2011
    • Sader H,Flamm R,Jones R.Antimicrobial activity of ceftaroline-avibactam tested against clinical isolates collected from US medical centers in 2010-2011.Antimicrob Agents Chemother. 2013;57:1982-1988
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 1982-1988
    • Sader, H.1    Flamm, R.2    Jones, R.3
  • 70
    • 77954197253 scopus 로고    scopus 로고
    • Activity of chequerboard combinations of ceftaroline and NXL104 versus beta-lactamase-producing Enterobacteriaceae
    • Mushtaq S,Warner M,Williams G,Critchley I,Livermore D.Activity of chequerboard combinations of ceftaroline and NXL104 versus beta-lactamase-producing Enterobacteriaceae.J Antimicrob Chemother. 2010;65:1428-1432
    • (2010) J Antimicrob Chemother , vol.65 , pp. 1428-1432
    • Mushtaq, S.1    Warner, M.2    Williams, G.3    Critchley, I.4    Livermore, D.5
  • 71
    • 84919640972 scopus 로고    scopus 로고
    • AztraZeneca. A study to investigate the effect of administration of ceftazidime-avibactam (CAZ-AVI) and ceftaroline fosamil-avibactam (CXL) on the intestinal flora of healthy volunteers. Accessed December 5, 2013
    • AztraZeneca. A study to investigate the effect of administration of ceftazidime-avibactam (CAZ-AVI) and ceftaroline fosamil-avibactam (CXL) on the intestinal flora of healthy volunteers. http://clinicaltrials.gov/ct2/show/NCT01789528. Accessed December 5, 2013.
  • 72
    • 84919640971 scopus 로고    scopus 로고
    • AstraZeneca. To investigate the safety and tolerability of aztreonam-avibactam (ATM-AVI). Accessed January 2, 2014
    • AstraZeneca. To investigate the safety and tolerability of aztreonam-avibactam (ATM-AVI). http://clinicaltrials.gov/show/NCT01689207. Accessed January 2, 2014.
  • 73
    • 78650636489 scopus 로고    scopus 로고
    • Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-producing Enterobacteriaceae
    • ,,, et al.. ;:-
    • Livermore DM,Mushtaq S,Warner M, et al.Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-producing Enterobacteriaceae.Antimicrob Agents Chemother. 2011;55:390-394
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 390-394
    • Livermore, D.M.1    Mushtaq, S.2    Warner, M.3
  • 75
    • 84888787952 scopus 로고    scopus 로고
    • Activity of MK-7655 combined with imipenem against Enterobacteriaceae and Pseudomonas aeruginosa
    • Livermore D,Warner M,Mushtaq S.Activity of MK-7655 combined with imipenem against Enterobacteriaceae and Pseudomonas aeruginosa.J Antimicrob Chemother. 2013;68:2286-2290
    • (2013) J Antimicrob Chemother , vol.68 , pp. 2286-2290
    • Livermore, D.1    Warner, M.2    Mushtaq, S.3
  • 76
    • 84862573378 scopus 로고    scopus 로고
    • In vitro activity of MK-7655, a novel beta-lactamase inhibitor, in combination with imipenem against carbapenem resistant Gram-negative bacteria
    • Hirsch E,Ledesma K,Chang KT,Schwartz M,Motyl M,Tam V.In vitro activity of MK-7655, a novel beta-lactamase inhibitor, in combination with imipenem against carbapenem resistant Gram-negative bacteria.Antimicrob Agents Chemother. 2012;56:3753-3757
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 3753-3757
    • Hirsch, E.1    Ledesma, K.2    Chang, K.T.3    Schwartz, M.4    Motyl, M.5    Tam, V.6
  • 78
    • 84919640968 scopus 로고    scopus 로고
    • Wayne, PA: ; :, Clinical Laboratory Standards Institute
    • Wayne, PA: Clinical Laboratory Standards Institute; 2007:
    • (2007)
  • 79
    • 84919640967 scopus 로고    scopus 로고
    • Wayne, PA: ; :, Clinical Laboratory Standards Institute
    • Wayne, PA: Clinical Laboratory Standards Institute; 2014:
    • (2014)
  • 80
    • 84919640966 scopus 로고    scopus 로고
    • Merck Sharp & Dohme Corp. Study of the safety, tolerability, and efficacy of MK-7655 + imipenem/cilastatin alone for the treatment of complicated urinary tract infection (cUTI). Accessed January 22, 2014
    • Merck Sharp & Dohme Corp. Study of the safety, tolerability, and efficacy of MK-7655 + imipenem/cilastatin alone for the treatment of complicated urinary tract infection (cUTI). http://clinicaltrials.gov/ct2/show/NCT01505634?term=MK-7655&rank=2. Accessed January 22, 2014.
  • 81
    • 84919640965 scopus 로고    scopus 로고
    • Merck Sharp & Dohme Corp. Study of the safety, tolerability, and efficacy of MK-7655 + imipenem/cilastatin versus imipenem/cilastatin alone to treat complicated intra-abdominal infection [cIAI]. Accessed January 15, 2014
    • Merck Sharp & Dohme Corp. Study of the safety, tolerability, and efficacy of MK-7655 + imipenem/cilastatin versus imipenem/cilastatin alone to treat complicated intra-abdominal infection [cIAI]. http://clinicaltrials.gov/ct2/show/NCT01506271?term=MK-7655&rank=3. Accessed January 15, 2014.
  • 82
    • 84919640964 scopus 로고    scopus 로고
    • Merck Sharp & Dohme Corp. Merck’s investigational beta-lactamase inhibitor relebactam (MK-7655) granted qualified infectious disease product (QIDP) and fast track designations by FDA. Accessed October 9, 2014
    • Merck Sharp & Dohme Corp. Merck’s investigational beta-lactamase inhibitor relebactam (MK-7655) granted qualified infectious disease product (QIDP) and fast track designations by FDA. http://www.mercknewsroom.com/news-release/cor-porate-news/mercks-investigational-beta-lactamase-inhibitor-relebactam-mk-7655-grant. Accessed October 9, 2014.
  • 83
    • 84919640963 scopus 로고    scopus 로고
    • Rempex Pharmaceuticals. Rempex Pharmaceuticals to present data at ICAAC on Carbavance, a new agent designed to treat multi-drug resistant (MDR) Gram-negative bacteria, September2012. Accessed January 18, 2014
    • Rempex Pharmaceuticals. Rempex Pharmaceuticals to present data at ICAAC on Carbavance, a new agent designed to treat multi-drug resistant (MDR) Gram-negative bacteria, September2012. http://www.rempexpharma.com/news/9-7-12. Accessed January 18, 2014.
  • 84
    • 0028214069 scopus 로고
    • In-vitro activity of biapenem, compared with imipenem and meropenem, against Pseudomonas aeruginosa strains and mutants with known resistance mechanisms
    • Chen HY,Livermore DM.In-vitro activity of biapenem, compared with imipenem and meropenem, against Pseudomonas aeruginosa strains and mutants with known resistance mechanisms.J Antimicrob Chemother. 1994;33:949-958
    • (1994) J Antimicrob Chemother , vol.33 , pp. 949-958
    • Chen, H.Y.1    Livermore, D.M.2
  • 85
    • 84880714408 scopus 로고    scopus 로고
    • Activity of biapenem (RPX2003) combined with the boronate beta-lactamase inhibitor RPX7009 against carbapenem-resistant Enterobacteriaceae
    • Livermore D,Mushtaq S.Activity of biapenem (RPX2003) combined with the boronate beta-lactamase inhibitor RPX7009 against carbapenem-resistant Enterobacteriaceae.J Antimicrob Chemother. 2013;68:1825-1831
    • (2013) J Antimicrob Chemother , vol.68 , pp. 1825-1831
    • Livermore, D.1    Mushtaq, S.2
  • 86
    • 84877858916 scopus 로고    scopus 로고
    • In vitro activity of biapenem plus RPX7009, a carbapenem combined with a serine beta-lactamase inhibitor, against anaerobic bacteria
    • Goldstein E,Citron D,Tyrrell K,Merriam C.In vitro activity of biapenem plus RPX7009, a carbapenem combined with a serine beta-lactamase inhibitor, against anaerobic bacteria.Antimicrob Agents Chemother. 2013;57:2620-2630
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 2620-2630
    • Goldstein, E.1    Citron, D.2    Tyrrell, K.3    Merriam, C.4
  • 87
    • 10544226874 scopus 로고    scopus 로고
    • Biapenem versus imipenem/cilastatin in the treatment of complicated intra-abdominal infections: report from a Swedish study group
    • ,,, et al.. ;:-
    • Brismar B,Akerlund JE,Sjostedt S, et al.Biapenem versus imipenem/cilastatin in the treatment of complicated intra-abdominal infections: report from a Swedish study group.Scand J Infect Dis. 1996;28:507-512
    • (1996) Scand J Infect Dis , vol.28 , pp. 507-512
    • Brismar, B.1    Akerlund, J.E.2    Sjostedt, S.3
  • 88
    • 84919640962 scopus 로고    scopus 로고
    • Efficacy, safety, tolerability of carbavance compared to best available therapy in serious infections due to carbapenem resistant Enterobacteriaceae, in adults. Accessed October 21, 2014
    • Efficacy, safety, tolerability of carbavance compared to best available therapy in serious infections due to carbapenem resistant Enterobacteriaceae, in adults. http://clinicaltrials.gov/ct2/show/NCT02168946?term=RPX7009&rank=6. Accessed October 21, 2014.
  • 89
    • 1642455995 scopus 로고    scopus 로고
    • Bacteremia due to Klebsiella pneumonia isolates producing the TEM-52 Extended-spectrum beta-lactamase: Treatment outcome of patients receiving imipenem or ciprofloxacin
    • Endimiani A,Luzzaro F,Perilli M.Bacteremia due to Klebsiella pneumonia isolates producing the TEM-52 Extended-spectrum beta-lactamase: Treatment outcome of patients receiving imipenem or ciprofloxacin.Clin Infect Dis. 2004;38:243-251
    • (2004) Clin Infect Dis , vol.38 , pp. 243-251
    • Endimiani, A.1    Luzzaro, F.2    Perilli, M.3
  • 90
    • 3042706689 scopus 로고    scopus 로고
    • Antibiotic therapy for Klebsiella pneumonia bacteremia: implications of the production of extended-spectrum beta-lactamases
    • ,,, et al.. ;:-
    • Paterson D,Wen-Chien K,Gottberg A, et al.Antibiotic therapy for Klebsiella pneumonia bacteremia: implications of the production of extended-spectrum beta-lactamases.Clin Infect Dis. 2003;39:31-37
    • (2003) Clin Infect Dis , vol.39 , pp. 31-37
    • Paterson, D.1    Wen-Chien, K.2    Gottberg, A.3
  • 91
    • 39049128343 scopus 로고    scopus 로고
    • Extended spectrum beta-lactamase producing Enterobacteriaceae: an emerging public-health concern
    • Pitout JD,Laupland KB.Extended spectrum beta-lactamase producing Enterobacteriaceae: an emerging public-health concern.Lancet Infect Dis. 2008;8:159-166
    • (2008) Lancet Infect Dis , vol.8 , pp. 159-166
    • Pitout, J.D.1    Laupland, K.B.2
  • 92
    • 0026667782 scopus 로고
    • Piperacillin, tazobactam, and gentamicin alone or combined in an endocarditis model of infection by a TEM-3-producing strain of Klebsiella pneumonia or its susceptible variant
    • ,,, et al.. ;:-
    • Mentec H,Vallois JM,Bure A, et al.Piperacillin, tazobactam, and gentamicin alone or combined in an endocarditis model of infection by a TEM-3-producing strain of Klebsiella pneumonia or its susceptible variant.Antimicrob Agents Chemother. 1992;36:1883-1889
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 1883-1889
    • Mentec, H.1    Vallois, J.M.2    Bure, A.3
  • 93
    • 0030063165 scopus 로고    scopus 로고
    • In vivo efficacies of beta-lactam beta-lactamase inhibitor combinations in Klebsiella pneumonia and in vivo response to beta-lactam therapy
    • Rice LB,Carias LL,Shales DM.In vivo efficacies of beta-lactam beta-lactamase inhibitor combinations in Klebsiella pneumonia and in vivo response to beta-lactam therapy.J Infect Dis. 1996;173:151-158
    • (1996) J Infect Dis , vol.173 , pp. 151-158
    • Rice, L.B.1    Carias, L.L.2    Shales, D.M.3
  • 94
    • 84555209226 scopus 로고    scopus 로고
    • Can we really use beta-lactam/beta-lactam inhibitor combinations for the treatment of infections caused by extended-spectrum beta-lactamase-producing bacteria?
    • Perez F,Bonomo R.Can we really use beta-lactam/beta-lactam inhibitor combinations for the treatment of infections caused by extended-spectrum beta-lactamase-producing bacteria?.Clin Infect Dis. 2012;54:175-177
    • (2012) Clin Infect Dis , vol.54 , pp. 175-177
    • Perez, F.1    Bonomo, R.2
  • 95
    • 0030956601 scopus 로고
    • Efficacies of piperacillin-tazobactam and cefepime in rats with experimental intra-abdominal abscesses due to an extended-spectrum beta-lactamase-producing strain of Klebsiella pneumonia
    • Thauvin-Eliopoulous C,Tripodi MF,Moellering JR,Eliopoulos GM.Efficacies of piperacillin-tazobactam and cefepime in rats with experimental intra-abdominal abscesses due to an extended-spectrum beta-lactamase-producing strain of Klebsiella pneumonia.Antimicrob Agents Chemother. 1994;41:1053-1057
    • (1994) Antimicrob Agents Chemother , vol.41 , pp. 1053-1057
    • Thauvin-Eliopoulous, C.1    Tripodi, M.F.2    Moellering, J.R.3    Eliopoulos, G.M.4
  • 96
    • 0035189967 scopus 로고    scopus 로고
    • Cefepime, piperacillin-tazobactam, and the inoculum effect in tests with extended-spectrum beta-lactamase-producing Enterobacteriaceae
    • Thompson K,Smith Moland E.Cefepime, piperacillin-tazobactam, and the inoculum effect in tests with extended-spectrum beta-lactamase-producing Enterobacteriaceae.Antimicrob Agents Chemother. 2001;45:3548-3554
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 3548-3554
    • Thompson, K.1    Smith Moland, E.2
  • 97
    • 74549187084 scopus 로고    scopus 로고
    • Comparative assessment of inoculum effects on the antimicrobial activity of amoxicillin/clavulanate and piperacillin/tazobactam with extended-spectrum beta-lactamase-producing and extended-spectrum beta-lactamase-nonproducing Escherichia coli isolates
    • ,,, et al.. ;:-
    • Lopez-Cerero L,Picon E,Morillo C, et al.Comparative assessment of inoculum effects on the antimicrobial activity of amoxicillin/clavulanate and piperacillin/tazobactam with extended-spectrum beta-lactamase-producing and extended-spectrum beta-lactamase-nonproducing Escherichia coli isolates.Clin Microbiol Infect. 2010;16:132-136
    • (2010) Clin Microbiol Infect , vol.16 , pp. 132-136
    • Lopez-Cerero, L.1    Picon, E.2    Morillo, C.3
  • 98
    • 84876224866 scopus 로고    scopus 로고
    • Inoculum effect on the efficacies of amoxicillin-clavulanate, piperacillin-tazobactam, and imipenem against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in an experimental murine sepsis model
    • ,,, et al.. ;:-
    • Docobo-Perez F,Lopez-Cereo L,Lopez-Rojas R, et al.Inoculum effect on the efficacies of amoxicillin-clavulanate, piperacillin-tazobactam, and imipenem against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in an experimental murine sepsis model.Antimicrob Agents Chemother. 2013;57:2109-2113
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 2109-2113
    • Docobo-Perez, F.1    Lopez-Cereo, L.2    Lopez-Rojas, R.3
  • 99
    • 0032517251 scopus 로고    scopus 로고
    • Class restriction of cephalosporin use to control total cephalosporin resistance in nosocomial Klebsiella
    • ,,, et al.. ;:-
    • Rahal JJ,Urban C,Horn D, et al.Class restriction of cephalosporin use to control total cephalosporin resistance in nosocomial Klebsiella.JAMA. 1998;280:1233-1237
    • (1998) JAMA , vol.280 , pp. 1233-1237
    • Rahal, J.J.1    Urban, C.2    Horn, D.3
  • 100
    • 84884220511 scopus 로고    scopus 로고
    • Correlations of antibiotic use and carbapenem resistance in Enterobacteriaceae
    • ,,, et al.. ;:-
    • McLaughlin M,Advincula MR,Malcynski M, et al.Correlations of antibiotic use and carbapenem resistance in Enterobacteriaceae.Antimicrob Agents Chemother. 2013;57:5131-5133
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 5131-5133
    • McLaughlin, M.1    Advincula, M.R.2    Malcynski, M.3
  • 101
    • 84900435221 scopus 로고    scopus 로고
    • Cefepime vs other antibacterial agents for the treatment of Enterobacter species bacteremia
    • ,,, et al.. ;:-
    • Siedner M,Galar A,Guzman-Suarez BB, et al.Cefepime vs other antibacterial agents for the treatment of Enterobacter species bacteremia.Clin Infect Dis. 2014;58:1554-1563
    • (2014) Clin Infect Dis , vol.58 , pp. 1554-1563
    • Siedner, M.1    Galar, A.2    Guzman-Suarez, B.B.3
  • 102
    • 84919640961 scopus 로고    scopus 로고
    • The efficacy of non-carbapenem antibiotics for the treatment of community-onset pyelonephritis due to extended-spectrum beta-lactamase-producing Escherichia coli
    • Park S,Choi S,Lee D.The efficacy of non-carbapenem antibiotics for the treatment of community-onset pyelonephritis due to extended-spectrum beta-lactamase-producing Escherichia coli.J Antimicrob Chemother. 2014;69:2848-2856
    • (2014) J Antimicrob Chemother , vol.69 , pp. 2848-2856
    • Park, S.1    Choi, S.2    Lee, D.3
  • 103
    • 84869484115 scopus 로고    scopus 로고
    • Carbapenems versus alternative antibiotics for the treatment of bacteremia due to Enterobacteriaceae producing extended-spectrum beta-lactamases: a systematic review and meta-analysis
    • Vardakas K,Tansarli G,Rafailidis P,Falagas M.Carbapenems versus alternative antibiotics for the treatment of bacteremia due to Enterobacteriaceae producing extended-spectrum beta-lactamases: a systematic review and meta-analysis.J Antimicrob Chemother. 2012;67:2793-2803
    • (2012) J Antimicrob Chemother , vol.67 , pp. 2793-2803
    • Vardakas, K.1    Tansarli, G.2    Rafailidis, P.3    Falagas, M.4
  • 104
    • 84555204766 scopus 로고    scopus 로고
    • Beta lactam/beta lactam inhibitor combinations for the treatment of bacteremia due to Extended-spectrum Beta-lactamase producing Escherichia coli: a post hoc analysis of prospective cohorts
    • ,,, et al.. ;:-
    • Rodriguez-Bano J,Navarro M,Retamar P, et al.Beta lactam/beta lactam inhibitor combinations for the treatment of bacteremia due to Extended-spectrum Beta-lactamase producing Escherichia coli: a post hoc analysis of prospective cohorts.Clin Infect Dis. 2012;54:167-174
    • (2012) Clin Infect Dis , vol.54 , pp. 167-174
    • Rodriguez-Bano, J.1    Navarro, M.2    Retamar, P.3
  • 105
    • 33744483523 scopus 로고    scopus 로고
    • Clinical correlation of CLSI susceptibility breakpoint for piperacillin-tazobactam against extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella species
    • Gavin P,Suseno M,Peterson L.Clinical correlation of CLSI susceptibility breakpoint for piperacillin-tazobactam against extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella species.Antimicrob Agents Chemother. 2006;50:2244-2247
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2244-2247
    • Gavin, P.1    Suseno, M.2    Peterson, L.3
  • 106
    • 33644617756 scopus 로고    scopus 로고
    • Outcomes evaluation of patients with ESBL and non-ESBL-producing Escherichia coli and Klebsiella species as defined by CLSI reference methods: report from the SENTRY Antimicrobial Surveillance Program
    • Bhavnani S,Ambrose P,Craig W.Outcomes evaluation of patients with ESBL and non-ESBL-producing Escherichia coli and Klebsiella species as defined by CLSI reference methods: report from the SENTRY Antimicrobial Surveillance Program.Diagn Microbiol Infect Dis. 2006;54:231-236
    • (2006) Diagn Microbiol Infect Dis , vol.54 , pp. 231-236
    • Bhavnani, S.1    Ambrose, P.2    Craig, W.3
  • 107
    • 9944248151 scopus 로고    scopus 로고
    • The inoculum effect: fact or artifact?
    • Craig W.The inoculum effect: fact or artifact?.Diagn Microbiol Infect Dis. 2004;50:229-230
    • (2004) Diagn Microbiol Infect Dis , vol.50 , pp. 229-230
    • Craig, W.1
  • 108
    • 84876003793 scopus 로고    scopus 로고
    • Background and rationale for revised clinical and laboratory standards institute interpretive criteria (breakpoints) for Entero-bacteriaceae and Pseudomonas aeruginosa: I. cephalosporins and aztreonam
    • ,,, et al.. ;:-
    • Dudley M,Ambrose P,Bhavnani SM, et al.Background and rationale for revised clinical and laboratory standards institute interpretive criteria (breakpoints) for Entero-bacteriaceae and Pseudomonas aeruginosa: I. cephalosporins and aztreonam.Clin Infect Dis. 2013;56:1301-1309
    • (2013) Clin Infect Dis , vol.56 , pp. 1301-1309
    • Dudley, M.1    Ambrose, P.2    Bhavnani, S.M.3
  • 109
    • 84879017251 scopus 로고    scopus 로고
    • Impact of the MIC of piperacillin/tazobactam on the outcome of patients with bacteremia due to extended-spectrum beta-lactamase-producing Escherichia coli
    • ,,, et al.. ;:-
    • Retamar P,Lopez-Cerero L,Muniain M, et al.Impact of the MIC of piperacillin/tazobactam on the outcome of patients with bacteremia due to extended-spectrum beta-lactamase-producing Escherichia coli.Antimicrob Agents Chemother. 2013;57:3402-3404
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 3402-3404
    • Retamar, P.1    Lopez-Cerero, L.2    Muniain, M.3
  • 110
    • 37249049746 scopus 로고    scopus 로고
    • Antibiotic policy and prescribing strategies for therapy of extended-spectrum beta-lactamase-producing Enterobacteriaceae: the role of piperacillin/tazobactam
    • Peterson L.Antibiotic policy and prescribing strategies for therapy of extended-spectrum beta-lactamase-producing Enterobacteriaceae: the role of piperacillin/tazobactam.Clin Microbiol Infect. 2008;14:181-184
    • (2008) Clin Microbiol Infect , vol.14 , pp. 181-184
    • Peterson, L.1
  • 111
    • 84875181975 scopus 로고    scopus 로고
    • Global spread of antibiotic resistance: the example of New Delhi metallo-beta-lactamase (NDM)-mediated carbapenem resistance
    • Johnson A,Woodford N.Global spread of antibiotic resistance: the example of New Delhi metallo-beta-lactamase (NDM)-mediated carbapenem resistance.J Med Microbiol. 2013;62:599-613
    • (2013) J Med Microbiol , vol.62 , pp. 599-613
    • Johnson, A.1    Woodford, N.2
  • 112
    • 84895516368 scopus 로고    scopus 로고
    • Increased waterborne blaNDM-1 resistance gene abundances associated with seasonal human pilgrimages to the upper Ganges river
    • Ahammad Z,Sreekrishnan T,Hands C,Knapp C,Graham D.Increased waterborne blaNDM-1 resistance gene abundances associated with seasonal human pilgrimages to the upper Ganges river.Environ Sci Technol. 2013;48:3014-3020
    • (2013) Environ Sci Technol , vol.48 , pp. 3014-3020
    • Ahammad, Z.1    Sreekrishnan, T.2    Hands, C.3    Knapp, C.4    Graham, D.5


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