Selenizing astragalus polysaccharide attenuates PCV2 replication promotion caused by oxidative stress through autophagy inhibition via PI3K/AKT activation

International Journal of Biological Macromolecules

Volumn 108, Issue , 2018, Pages 350-359

  Liu, Dandan ^a   Xu, Jing ^a   Qian, Gang ^a   Hamid, Mohammed ^a   Gan, Fang ^a   Chen, Xingxiang ^a   Huang, Kehe ^a  

^a NANJING AGRICULTURAL UNIVERSITY   (China)

Author keywords

Autophagy; LY294002; Oxidative stress; PCV2; PI3K AKT; Selenizing astragalus polysaccharide

Indexed keywords

3 METHYLADENINE; ANTIVIRUS AGENT; AUTOPHAGY RELATED PROTEIN 5; HYDROGEN PEROXIDE; IMMUNOGLOBULIN LIGHT CHAIN; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; POLYSACCHARIDE; PROTEIN KINASE B; SELENIZING ASTRAGALUS POLYSACCHARIDE; SMALL INTERFERING RNA; SODIUM SELENITE; UNCLASSIFIED DRUG; PLANT EXTRACT; TARGET OF RAPAMYCIN KINASE;

ANTIVIRAL ACTIVITY; ARTICLE; AUTOPHAGY INHIBITION; CELL VIABILITY; COMBINATION CHEMOTHERAPY; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; GENE DOSAGE; GENE SILENCING; INFRARED SPECTROSCOPY; MONOTHERAPY; MTT ASSAY; NONHUMAN; OXIDATIVE STRESS; PORCINE CIRCOVIRUS 2; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SCANNING ELECTRON MICROSCOPY; VIRUS REPLICATION; ANIMAL; ASTRAGALUS (PLANT); AUTOPHAGY; CELL LINE; CELL SURVIVAL; CHEMISTRY; CIRCOVIRUS; METABOLISM; PHOSPHORYLATION; PIG; SIGNAL TRANSDUCTION;

ANIMALS; ASTRAGALUS PLANT; AUTOPHAGY; CELL LINE; CELL SURVIVAL; CIRCOVIRUS; HYDROGEN PEROXIDE; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PLANT EXTRACTS; POLYSACCHARIDES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SODIUM SELENITE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SWINE; TOR SERINE-THREONINE KINASES; VIRUS REPLICATION;

EID: 85037618367     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2017.12.010     Document Type: Article

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