Apelin inhibits the proliferation and migration of rat PASMCs via the activation of PI3K/Akt/mTOR signal and the inhibition of autophagy under hypoxia

Journal of Cellular and Molecular Medicine

Volumn 18, Issue 3, 2014, Pages 542-553

  Zhang, Hongyu ^a   Gong, Yongsheng ^a   Wang, Zhouguang ^a   Jiang, Liping ^a   Chen, Ran ^a   Fan, Xiaofang ^a   Zhu, Huanmian ^a   Han, Liping ^a   Li, Xiaokun ^a   Xiao, Jian ^a   Kong, Xiaoxia ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Apelin; Autophagy; Hypoxia; PI3K Akt mTOR; Smooth muscle cells

Indexed keywords

3-METHYLADENINE; ADENINE; ADIPOCYTOKINE; APLN PROTEIN, MOUSE; G PROTEIN COUPLED RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SIGNAL PEPTIDE; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE;

ANALOGS AND DERIVATIVES; ANIMAL; AUTOPHAGY; CELL CULTURE; CELL CYCLE; CELL HYPOXIA; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; GENETIC TRANSFECTION; METABOLISM; MOUSE; PULMONARY ARTERY; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; WISTAR RAT;

ADENINE; ADIPOKINES; ANIMALS; AUTOPHAGY; CELL CYCLE; CELL HYPOXIA; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MYOCYTES, SMOOTH MUSCLE; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-AKT; PULMONARY ARTERY; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSFECTION;

EID: 84894568741     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12208     Document Type: Article

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