An Iron-Rich Diet Decreases the Mycobacterial Burden and Correlates with Hepcidin Upregulation, Lower Levels of Proinflammatory Mediators, and Increased T-Cell Recruitment in a Model of Mycobacterium bovis Bacille Calmette-Guerin Infection

Journal of Infectious Diseases

Volumn 216, Issue 7, 2017, Pages 907-918

  Agoro, Rafiou ^a,b   Benmerzoug, Sulayman ^a,b   Rose, Stéphanie ^a,b   Bouyer, Mélanie ^a,b   Gozzelino, Raffaella ^c   Garcia, Irene ^d   Ryffel, Bernhard ^a,b   Quesniaux, Valerie F J ^a,b   Mura, Catherine ^a,b  

^a CNRS   (France)

^b UNIVERSITÉ D'ORLÉANS   (France)

^c NOVA MEDICAL SCHOOL   (Portugal)

^d UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

hepcidin; inflammation; iron; Mycobacterium bovis BCG infection

Indexed keywords

GREEN FLUORESCENT PROTEIN; HEPCIDIN; REACTIVE OXYGEN METABOLITE; CYTOKINE; IRON;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL GROWTH; BACTERIAL LOAD; BONE MARROW CELL; BOVINE TUBERCULOSIS; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; GENETIC CODE; GRANULOMA; IN VIVO STUDY; IRON INTAKE; MACROPHAGE; MALE; MOUSE; MYCOBACTERIUM BOVIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; UPREGULATION; ANIMAL; GENETICS; IMMUNOLOGY; LIVER; LUNG; METABOLISM; MICROBIOLOGY; PHARMACOLOGY; PHYSIOLOGY; TUBERCULOSIS;

ANIMALS; CYTOKINES; HEPCIDINS; IRON; IRON, DIETARY; LIVER; LUNG; MICE; MYCOBACTERIUM BOVIS; T-LYMPHOCYTES; TUBERCULOSIS; UP-REGULATION;

EID: 85035000514     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jix366     Document Type: Article

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