Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior

Nature Immunology

Volumn 18, Issue 12, 2017, Pages 1342-1352

  Miyajima, Michio ^a   Zhang, Baihao ^a,b   Sugiura, Yuki ^c   Sonomura, Kazuhiro ^b   Guerrini, Matteo M ^a   Tsutsui, Yumi ^a   Maruya, Mikako ^a   Vogelzang, Alexis ^a   Chamoto, Kenji ^a   Honda, Kurara ^c   Hikida, Takatoshi ^b   Ito, Satomi ^a   Qin, Hongyan ^d   Sanuki, Rikako ^e   Suzuki, Keiichiro ^a   Furukawa, Takahisa ^e   Ishihama, Yasushi ^f   Matsuda, Fumihiko ^b   Suematsu, Makoto ^c   Honjo, Tasuku ^b   Fagarasan, Sidonia ^a   more..

^a RIKEN Center for Integrative Medical Sciences   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^e OSAKA UNIVERSITY   (Japan)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINO ACID; BRAIN MONOAMINE; DOPAMINE; FLUOXETINE; GAMMA INTERFERON; PHENELZINE; PROGRAMMED DEATH 1 RECEPTOR; SEROTONIN; TRYPTOPHAN; TYROSINE; AMINO ACID; KYNURENINE; PDCD1 PROTEIN, MOUSE;

AMINO ACID BLOOD LEVEL; ANIMAL BEHAVIOR; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; BEHAVIOR CHANGE; CELL METABOLISM; EMOTION; FEAR; INTESTINE FLORA; LOCOMOTION; LYMPH NODE; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN DEPLETION; T LYMPHOCYTE ACTIVATION; ANIMAL; ANXIETY; BLOOD; BRAIN; C57BL MOUSE; DEFICIENCY; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; T LYMPHOCYTE;

AMINO ACIDS; ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BRAIN; DOPAMINE; FEAR; INTERFERON-GAMMA; KYNURENINE; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROGRAMMED CELL DEATH 1 RECEPTOR; SEROTONIN; T-LYMPHOCYTES; TRYPTOPHAN; TYROSINE;

EID: 85034582678     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3867     Document Type: Article

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