-
1
-
-
84941053261
-
GRASP v2 0: An update on the Genome-Wide Repository of Associations between SNPs and phenotypes
-
Eicher JD, Landowski C, Stackhouse B, Sloan A, Chen W, Jensen N et al. GRASP v2.0: an update on the Genome-Wide Repository of Associations between SNPs and phenotypes. Nucleic Acids Res 2015; 43: D799-D804.
-
(2015)
Nucleic Acids Res
, vol.43
, pp. D799-D804
-
-
Eicher, J.D.1
Landowski, C.2
Stackhouse, B.3
Sloan, A.4
Chen, W.5
Jensen, N.6
-
3
-
-
84908890496
-
Defining the role of common variation in the genomic and biological architecture of adult human height
-
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet 2014; 46: 1173-1186.
-
(2014)
Nat Genet
, vol.46
, pp. 1173-1186
-
-
Wood, A.R.1
Esko, T.2
Yang, J.3
Vedantam, S.4
Pers, T.H.5
Gustafsson, S.6
-
4
-
-
84923171580
-
Genetic studies of body mass index yield new insights for obesity biology
-
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR et al. Genetic studies of body mass index yield new insights for obesity biology. Nature 2015; 518: 197-206.
-
(2015)
Nature
, vol.518
, pp. 197-206
-
-
Locke, A.E.1
Kahali, B.2
Berndt, S.I.3
Justice, A.E.4
Pers, T.H.5
Day, F.R.6
-
5
-
-
84876007072
-
Power and predictive accuracy of polygenic risk scores
-
Dudbridge F. Power and predictive accuracy of polygenic risk scores. PLoS Genet 2013; 9: e1003348.
-
(2013)
PLoS Genet
, vol.9
, pp. e1003348
-
-
Dudbridge, F.1
-
6
-
-
84938971555
-
A fast method that uses polygenic scores to estimate the variance explained by genome-wide marker panels and the proportion of variants affecting a trait
-
Palla L, Dudbridge F. A fast method that uses polygenic scores to estimate the variance explained by genome-wide marker panels and the proportion of variants affecting a trait. Am J Hum Genet 2015; 97: 250-259.
-
(2015)
Am J Hum Genet
, vol.97
, pp. 250-259
-
-
Palla, L.1
Dudbridge, F.2
-
8
-
-
84976604384
-
A plethora of pleiotropy across complex traits
-
Visscher PM, Yang J. A plethora of pleiotropy across complex traits. Nat Genet 2016; 48: 707-708.
-
(2016)
Nat Genet
, vol.48
, pp. 707-708
-
-
Visscher, P.M.1
Yang, J.2
-
9
-
-
85000692305
-
An atlas of genetic correlations across human diseases and traits
-
Bulik-Sullivan B, Finucane HK, Anttila V, Gusev A, Day FR, Loh P-R et al. An atlas of genetic correlations across human diseases and traits. Nat Genet 2015; 47: 1236-1241.
-
(2015)
Nat Genet
, vol.47
, pp. 1236-1241
-
-
Bulik-Sullivan, B.1
Finucane, H.K.2
Anttila, V.3
Gusev, A.4
Day, F.R.5
Loh, P.-R.6
-
10
-
-
84968649781
-
Detection and interpretation of shared genetic influences on 42 human traits
-
Pickrell JK, Berisa T, Liu JZ, Ségurel L, Tung JY, Hinds DA. Detection and interpretation of shared genetic influences on 42 human traits. Nat Genet 2016; 48: 709-717.
-
(2016)
Nat Genet
, vol.48
, pp. 709-717
-
-
Pickrell, J.K.1
Berisa, T.2
Liu, J.Z.3
Ségurel, L.4
Tung, J.Y.5
Hinds, D.A.6
-
11
-
-
84940099341
-
Phenome-wide analysis of genome-wide polygenic scores
-
Krapohl E, Euesden J, Zabaneh D, Pingault J-B, Rimfeld K, von Stumm S et al. Phenome-wide analysis of genome-wide polygenic scores. Mol Psychiatry 2016; 21: 1188-1193.
-
(2016)
Mol Psychiatry
, vol.21
, pp. 1188-1193
-
-
Krapohl, E.1
Euesden, J.2
Zabaneh, D.3
Pingault, J.-B.4
Rimfeld, K.5
Von Stumm, S.6
-
12
-
-
84879419343
-
Pleiotropy in complex traits: Challenges and strategies
-
Solovieff N, Cotsapas C, Lee PH, Purcell SM, Smoller JW. Pleiotropy in complex traits: challenges and strategies. Nat Rev Genet 2013; 14: 483-495.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 483-495
-
-
Solovieff, N.1
Cotsapas, C.2
Lee, P.H.3
Purcell, S.M.4
Smoller, J.W.5
-
13
-
-
16244401458
-
Regularization and variable selection via the elastic net
-
Zou H, Hastie T. Regularization and variable selection via the elastic net. J R Stat Soc Ser B Stat Methodol 2005; 67: 301-320.
-
(2005)
J R Stat Soc ser B Stat Methodol
, vol.67
, pp. 301-320
-
-
Zou, H.1
Hastie, T.2
-
14
-
-
84925130699
-
Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder
-
Cross-Disorder Working Group of the Psychiatric Genomics Consortium
-
Maier R, Moser G, Chen G-B, Ripke S, Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Coryell W et al. Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. Am J Hum Genet 2015; 96: 283-294.
-
(2015)
Am J Hum Genet
, vol.96
, pp. 283-294
-
-
Maier, R.1
Moser, G.2
Chen, G.-B.3
Ripke, S.4
Coryell, W.5
-
15
-
-
85046789976
-
Multivariate genome-wide and integrated transcriptome and epigenome-wide analyses of the well-being spectrum
-
Baselmans BM, Jansen R, Dongen J, van, Bao Y, Smart M, Kumari M et al. Multivariate genome-wide and integrated transcriptome and epigenome-wide analyses of the well-being spectrum. bioRxiv 2017; doi: 10.1101/115915.
-
(2017)
BioRxiv
-
-
Baselmans, B.M.1
Jansen, R.2
Dongen, J.3
Van4
Bao, Y.5
Smart, M.6
Kumari, M.7
-
17
-
-
85021824295
-
MTAG: Multi-trait analysis of GWAS
-
Turley P, Walters RK, Maghzian O, Okbay A, Lee JJ, Fontana MA et al. MTAG: multi-trait analysis of GWAS. bioRxiv 2017; doi: 10.1101/118810.
-
(2017)
BioRxiv
-
-
Turley, P.1
Walters, R.K.2
Maghzian, O.3
Okbay, A.4
Lee, J.J.5
Fontana, M.A.6
-
18
-
-
84978645459
-
Predicting educational achievement from DNA
-
Selzam S, Krapohl E, von Stumm S, O'Reilly PF, Rimfeld K, Kovas Y et al. Predicting educational achievement from DNA. Mol Psychiatry 2017; 22: 267-272.
-
(2017)
Mol Psychiatry
, vol.22
, pp. 267-272
-
-
Selzam, S.1
Krapohl, E.2
Von Stumm, S.3
O'Reilly, P.F.4
Rimfeld, K.5
Kovas, Y.6
-
19
-
-
84958839102
-
Genetic link between family socioeconomic status and children's educational achievement estimated from genome-wide SNPs
-
Krapohl E, Plomin R. Genetic link between family socioeconomic status and children's educational achievement estimated from genome-wide SNPs. Mol Psychiatry 2016; 21: 437-443.
-
(2016)
Mol Psychiatry
, vol.21
, pp. 437-443
-
-
Krapohl, E.1
Plomin, R.2
-
20
-
-
36049033420
-
The genetic and environmental origins of learning abilities and disabilities in the early school years
-
Kovas Y, Haworth CMA, Dale PS, Plomin R. The genetic and environmental origins of learning abilities and disabilities in the early school years. Monogr Soc Res Child Dev 2007; 72, vii 1-144.
-
(2007)
Monogr Soc Res Child Dev
, vol.72
, pp. 1-144
-
-
Kovas, Y.1
Haworth, C.M.A.2
Dale, P.S.3
Plomin, R.4
-
21
-
-
84983479616
-
A reference panel of 64,976 haplotypes for genotype imputation
-
35170
-
McCarthy S, Das S, Kretzschmar W, Durbin R, Abecasis G, Marchini J. A reference panel of 64,976 haplotypes for genotype imputation. bioRxiv 2015; 48: 1279-1283, 35170.
-
(2015)
BioRxiv
, vol.48
, pp. 1279-1283
-
-
McCarthy, S.1
Das, S.2
Kretzschmar, W.3
Durbin, R.4
Abecasis, G.5
Marchini, J.6
-
22
-
-
85028296791
-
LD Hub: A centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
-
Zheng J, Erzurumluoglu AM, Elsworth BL, Kemp JP, Howe L, Haycock PC et al. LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis. Bioinformatics 2017; 33: 272-279.
-
(2017)
Bioinformatics
, vol.33
, pp. 272-279
-
-
Zheng, J.1
Erzurumluoglu, A.M.2
Elsworth, B.L.3
Kemp, J.P.4
Howe, L.5
Haycock, P.C.6
-
23
-
-
84923946495
-
LD score regression distinguishes confounding from polygenicity in genome-wide association studies
-
Schizophrenia Working Group of the Psychiatric Genomics Consortium
-
Bulik-Sullivan BK, Loh P-R, Finucane HK, Ripke S, Yang J, Schizophrenia Working Group of the Psychiatric Genomics Consortium et al. LD score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat Genet 2015; 47: 291-295.
-
(2015)
Nat Genet
, vol.47
, pp. 291-295
-
-
Bulik-Sullivan, B.K.1
Loh, P.-R.2
Finucane, H.K.3
Ripke, S.4
Yang, J.5
-
24
-
-
84952665106
-
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
-
Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S et al. Modeling linkage disequilibrium increases accuracy of polygenic risk scores. Am J Hum Genet 2015; 97: 576-592.
-
(2015)
Am J Hum Genet
, vol.97
, pp. 576-592
-
-
Vilhjálmsson, B.J.1
Yang, J.2
Finucane, H.K.3
Gusev, A.4
Lindström, S.5
Ripke, S.6
-
25
-
-
56249113343
-
Building predictive models in R using the caret package
-
Kuhn M. Building predictive models in R using the caret package. J Stat Softw 2008; 28: 1-26.
-
(2008)
J Stat Softw
, vol.28
, pp. 1-26
-
-
Kuhn, M.1
-
26
-
-
85194972808
-
Regression shrinkage and selection via the Lasso
-
Tibshirani R. Regression shrinkage and selection via the Lasso. J R Stat Soc Ser B Methodol 1996; 58: 267-288.
-
(1996)
J R Stat Soc ser B Methodol
, vol.58
, pp. 267-288
-
-
Tibshirani, R.1
-
27
-
-
84879166428
-
On grouping effect of elastic net
-
Zhou D-X. On grouping effect of elastic net. Stat Probab Lett 2013; 83: 2108-2112.
-
(2013)
Stat Probab Lett
, vol.83
, pp. 2108-2112
-
-
Zhou, D.-X.1
-
28
-
-
77950537175
-
Regularization paths for generalized linear models via coordinate descent
-
Friedman J, Hastie T, Tibshirani R. Regularization paths for generalized linear models via coordinate descent. J Stat Softw 2010; 33: 1-22.
-
(2010)
J Stat Softw
, vol.33
, pp. 1-22
-
-
Friedman, J.1
Hastie, T.2
Tibshirani, R.3
-
29
-
-
85164392958
-
A study of cross-validation and bootstrap for accuracy estimation and model selection
-
Morgan Kaufmann Publishers Inc. : San Francisco, CA, USA, 1995 (cited 14 December
-
Kohavi R. A study of cross-validation and bootstrap for accuracy estimation and model selection. In: Proceedings of the 14th International Joint Conference on Artificial Intelligence- Volume 2. Morgan Kaufmann Publishers Inc.: San Francisco, CA, USA, 1995 (cited 14 December 2016), pp 1137-1143. Available from http://dl. acm.org/citation.cfm?id = 1643031.1643047.
-
(2016)
Proceedings of the 14th International Joint Conference on Artificial Intelligence- Volume 2
, pp. 1137-1143
-
-
Kohavi, R.1
-
30
-
-
84950461478
-
Estimating the error rate of a prediction rule: Improvement on cross-validation
-
Efron B. Estimating the error rate of a prediction rule: improvement on cross-validation. J Am Stat Assoc 1983; 78: 316-331.
-
(1983)
J Am Stat Assoc
, vol.78
, pp. 316-331
-
-
Efron, B.1
-
31
-
-
0031536511
-
Improvements on cross-validation: The 632+ bootstrap method
-
Efron B, Tibshirani R. Improvements on cross-validation: the 632+ bootstrap method. J Am Stat Assoc 1997; 92: 548-560.
-
(1997)
J Am Stat Assoc
, vol.92
, pp. 548-560
-
-
Efron, B.1
Tibshirani, R.2
-
32
-
-
65749119811
-
Estimating classification error rate: Repeated cross-validation, repeated hold-out and bootstrap
-
Kim J-H. Estimating classification error rate: repeated cross-validation, repeated hold-out and bootstrap. Comput Stat Data Anal 2009; 53: 3735-3745.
-
(2009)
Comput Stat Data Anal
, vol.53
, pp. 3735-3745
-
-
Kim, J.-H.1
-
33
-
-
0003834725
-
-
McGraw Hill Medical Book: New York
-
Malenka RC, Nestler E, Hyman S, Sydor A, Brown R. Molecular Neuropharmacology: A Foundation for Clinical Neuroscience. McGraw Hill Medical Book: New York, 2009.
-
(2009)
Molecular Neuropharmacology: A Foundation for Clinical Neuroscience
-
-
Malenka, R.C.1
Nestler, E.2
Hyman, S.3
Sydor, A.4
Brown, R.5
-
34
-
-
0344643407
-
Inhibition of subliminally primed responses is mediated by the caudate and thalamus: Evidence from functional MRI and Huntington's disease
-
Aron AR, Schlaghecken F, Fletcher PC, Bullmore ET, Eimer M, Barker R et al. Inhibition of subliminally primed responses is mediated by the caudate and thalamus: evidence from functional MRI and Huntington's disease. Brain 2003; 126: 713-723.
-
(2003)
Brain
, vol.126
, pp. 713-723
-
-
Aron, A.R.1
Schlaghecken, F.2
Fletcher, P.C.3
Bullmore, E.T.4
Eimer, M.5
Barker, R.6
-
35
-
-
84948069327
-
A fronto-striato-subthalamicpallidal network for goal-directed and habitual inhibition
-
Jahanshahi M, Obeso I, Rothwell JC, Obeso JA. A fronto-striato-subthalamicpallidal network for goal-directed and habitual inhibition. Nat Rev Neurosci 2015; 16: 719-732.
-
(2015)
Nat Rev Neurosci
, vol.16
, pp. 719-732
-
-
Jahanshahi, M.1
Obeso, I.2
Rothwell, J.C.3
Obeso, J.A.4
-
36
-
-
15244353512
-
The roles of the caudate nucleus in human classification learning
-
Seger CA, Cincotta CM. The roles of the caudate nucleus in human classification learning. J Neurosci 2005; 25: 2941-2951.
-
(2005)
J Neurosci
, vol.25
, pp. 2941-2951
-
-
Seger, C.A.1
Cincotta, C.M.2
-
37
-
-
43049090829
-
A probability-based measure of effect size: Robustness to base rates and other factors
-
Ruscio J. A probability-based measure of effect size: robustness to base rates and other factors. Psychol Methods 2008; 13: 19-30.
-
(2008)
Psychol Methods
, vol.13
, pp. 19-30
-
-
Ruscio, J.1
-
39
-
-
84957109611
-
Body mass index is associated with inflammatory bowel disease: A systematic review and meta-analysis
-
Dong J, Chen Y, Tang Y, Xu F, Yu C, Li Y et al. Body mass index is associated with inflammatory bowel disease: a systematic review and meta-analysis. PLoS ONE 2015; 10: e0144872.
-
(2015)
PLoS ONE
, vol.10
, pp. e0144872
-
-
Dong, J.1
Chen, Y.2
Tang, Y.3
Xu, F.4
Yu, C.5
Li, Y.6
-
40
-
-
84908121749
-
Research review: Polygenic methods and their application to psychiatric traits
-
Wray NR, Lee SH, Mehta D, Vinkhuyzen AAE, Dudbridge F, Middeldorp CM. Research review: polygenic methods and their application to psychiatric traits. J Child Psychol Psychiatry 2014; 55: 1068-1087.
-
(2014)
J Child Psychol Psychiatry
, vol.55
, pp. 1068-1087
-
-
Wray, N.R.1
Lee, S.H.2
Mehta, D.3
Vinkhuyzen, A.A.E.4
Dudbridge, F.5
Middeldorp, C.M.6
-
41
-
-
85037364395
-
An efficient Bayesian meta-analysis approach for studying cross-phenotype genetic associations
-
Majumdar A, Haldar T, Bhattacharya S, Witte J. An efficient Bayesian meta-analysis approach for studying cross-phenotype genetic associations. bioRxiv. 2017; doi: 10.1101/101543.
-
(2017)
BioRxiv.
-
-
Majumdar, A.1
Haldar, T.2
Bhattacharya, S.3
Witte, J.4
-
42
-
-
84920858732
-
Meta-analysis of correlated traits via summary statistics from GWASs with an application in hypertension
-
Zhu X, Feng T, Tayo BO, Liang J, Young JH, Franceschini N et al. Meta-analysis of correlated traits via summary statistics from GWASs with an application in hypertension. Am J Hum Genet 2015; 96: 21-36.
-
(2015)
Am J Hum Genet
, vol.96
, pp. 21-36
-
-
Zhu, X.1
Feng, T.2
Tayo, B.O.3
Liang, J.4
Young, J.H.5
Franceschini, N.6
-
43
-
-
84860771128
-
A subset-based approach improves power and interpretation for the combined analysis of genetic association studies of heterogeneous traits
-
Bhattacharjee S, Rajaraman P, Jacobs KB, Wheeler WA, Melin BS, Hartge P et al. A subset-based approach improves power and interpretation for the combined analysis of genetic association studies of heterogeneous traits. Am J Hum Genet 2012; 90: 821-835.
-
(2012)
Am J Hum Genet
, vol.90
, pp. 821-835
-
-
Bhattacharjee, S.1
Rajaraman, P.2
Jacobs, K.B.3
Wheeler, W.A.4
Melin, B.S.5
Hartge, P.6
-
44
-
-
84928253865
-
A multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians
-
Shim H, Chasman DI, Smith JD, Mora S, Ridker PM, Nickerson DA et al. A multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians. PLOS ONE 2015; 10: e0120758.
-
(2015)
PLOS ONE
, vol.10
, pp. e0120758
-
-
Shim, H.1
Chasman, D.I.2
Smith, J.D.3
Mora, S.4
Ridker, P.M.5
Nickerson, D.A.6
-
45
-
-
84897389512
-
A multi-trait, meta-analysis for detecting pleiotropic polymorphisms for stature, fatness and reproduction in beef cattle
-
Bolormaa S, Pryce JE, Reverter A, Zhang Y, Barendse W, Kemper K et al. A multi-trait, meta-analysis for detecting pleiotropic polymorphisms for stature, fatness and reproduction in beef cattle. PLOS Genet 2014; 10: e1004198.
-
(2014)
PLOS Genet
, vol.10
, pp. e1004198
-
-
Bolormaa, S.1
Pryce, J.E.2
Reverter, A.3
Zhang, Y.4
Barendse, W.5
Kemper, K.6
|