Inhibition of subliminally primed responses is mediated by the caudate and thalamus: Evidence from functional MRI and Huntington's disease

Brain

Volumn 126, Issue 3, 2003, Pages 713-723

  Aron, A R ^a   Schlaghecken, F ^d   Fletcher, P C ^a   Bullmore, E T ^a   Eimer, M ^e   Barker, R ^b   Sahakian, B J ^a   Robbins, T W ^c,f  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c Cambridge Centre for Brain Repair ^*  (United Kingdom)

^d UNIVERSITY OF WARWICK   (United Kingdom)

^e UNIVERSITY OF LONDON   (United Kingdom)

^f University of Cambridge   (United Kingdom)

Author keywords

Compatibility; Motor control; Priming; Striatum; Subliminal

Indexed keywords

ADULT; ARTICLE; BRAIN FUNCTION; CAUDATE NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; FEMALE; GLOBUS PALLIDUS; HUMAN; HUNTINGTON CHOREA; MALE; MOTOR CONTROL; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PERCEPTIVE THRESHOLD; PRIORITY JOURNAL; TASK PERFORMANCE; THALAMUS;

ADULT; ANALYSIS OF VARIANCE; BRAIN MAPPING; CASE-CONTROL STUDIES; CAUDATE NUCLEUS; FEMALE; HUMANS; HUNTINGTON DISEASE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PSYCHOMOTOR PERFORMANCE; REACTION TIME; THALAMUS;

EID: 0344643407     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/awg067     Document Type: Article

References (34)

1. Albin RL, Reiner A, Anderson KD, Penney JB, Young AB. Striatal and nigral neuron subpopulations in rigid Huntington's disease: implications for the functional anatomy of chorea and rigidity-akinesia. Ann Neurol 1990; 27: 357-65.
2. Alexander GE, Crutcher MD, DeLong MR. Basal gangliathalamocortical circuits: parallel substrates for motor, oculomotor, 'prefrontal' and 'limbic' functions. [Review]. Prog Brain Res 1990; 85: 119-46.
3. Beiser DG, Hua SE, Houk JC. Network models of the basal ganglia. [Review]. Curr Opin Neurobiol 1997; 7: 185-90.
4. Bruyn GW, Went LN. Huntington's chorea. In: Vinken PJ, Bruyn GW, Klawans HL, editors. Handbook of clinical neurology, Vol. 49. Amsterdam: Elsevier; 1986. p. 267-313.
5. Coles MG, Gratton G, Bashore TR, Eriksen CW, Donchin E. A psychophysiological investigation of the continuous flow model of human information processing. J Exp Psychol Hum Percept Perform 1985; 11: 529-53.
6. De Jong R, Coles MG, Logan GD. Strategies and mechanisms in nonselective and selective inhibitory motor control. J Exp Psychol Hum Percept Perform 1995; 21: 498-511.
7. Dehaene S, Naccache L, Le Clec'H G, Koechlin E, Mueller M, Dehaene-Lambertz G, et al. Imaging unconscious semantic priming. Nature 1998; 395: 597-600.
8. Eimer M. Stimulus-response compatibility and automatic response activation: evidence from psychophysiological studies. J Exp Psychol Hum Percept Perform 1995; 21: 837-54.
9. Eimer M. Facilitatory and inhibitory effects of masked prime stimuli on motor activation and behavioural performance. Acta Psychol (Amst) 1999; 101: 293-313.
10. Eimer M, Schlaghecken F. Effects of masked stimuli on motor activation: behavioral and electrophysiological evidence. J Exp Psychol Hum Percept Perform 1998; 24: 1737-47.
11. Eimer M, Schlaghecken F. Response facilitation and inhibition in manual, vocal, and oculomotor performance: evidence for a modality-unspecific mechanism. J Mot Behav 2001; 33: 16-26.
12. Georgiou N, Bradshaw JL, Phillips JG, Bradshaw JA, Chiu E. The Simon effect and attention deficits in Gilles de la Tourette's syndrome and Huntington's disease. Brain 1995; 118: 1305-18.
13. Gratton G, Coles MG, Sirevaag EJ, Eriksen CW, Donchin E. Pre- and poststimulus activation of response channels: a psychophysiological analysis. J Exp Psychol Hum Percept Perform 1988; 14: 331-44.
14. Gusnard DA, Raichle ME. Searching for a baseline: functional imaging and the resting human brain. [Review]. Nat Rev Neurosci 2001; 2: 685-94.
15. Klotz W, Wolff P. The effect of a masked stimulus on the response to the masking stimulus. Psychol Res 1995; 58: 92-101.
16. Lasker AG, Zee DS, Hain TC, Folstein SE, Singer HS. Saccades in Huntington's disease: initiation defects and distractibility. Neurology 1987; 37: 364-70.
17. Louis ED, Anderson KE, Moskowitz C, Thome DZ, Marder K. Dystonia-predominant adult-onset Huntington disease: association between motor phenotype and age of onset in adults. Arch Neurol 2000; 57: 1326-30.
18. Miller J, Hackley SA. Electrophysiological evidence for temporal overlap among contingent mental processes. J Exp Psychol Gen 1992; 121: 195-209.
19. Mink JW. The basal ganglia: focused selection and inhibition of competing motor programs. [Review]. Prog Neurobiol 1996; 50: 381-425.
20. Naccache L, Dehaene S. The priming method: imaging unconscious repetition priming reveals an abstract representation of number in the parietal lobes. Cereb Cortex 2001; 11: 966-74.
21. Neumann O, Klotz W. Motor responses to nonreportable, masked stimuli: where is the limit of direct parameter specification? In: Umilta C, Moscovitch M, editors. Attention and performance XV: Conscious and nonconscious information processing. Cambridge, MA: MIT Press; 1994; p. 123-50
22. Rorden C, Brett M. Stereotaxic display of brain lesions. Behav Neurol 2000; 12: 191-200.
23. Rosas HD, Goodman J, Chen YI, Jenkins BG, Kennedy DN, Makris N, et al. Striatal volume loss in HD as measured by MRI and the influence of CAG repeat. Neurology 2001; 57: 1025-8.
24. Schacter DL, Buckner RL. Priming and the brain. [Review]. Neuron 1998; 20: 185-95.
25. Schlaghecken F, Eimer M. The influence of subliminally presented primes on response preparation. Sprache Kognition 1997; 16: 166-75.
26. Schlaghecken F, Eimer M. A central-peripheral asymmetry in masked priming. Percept Psychophys 2000; 62: 1367-82.
27. Schlaghecken F, Eimer M. Partial response activation to masked primes is not dependent on response readiness. Percept Mot Skills 2001; 92: 208-22.
28. Schlaghecken F, Eimer M. Motor activation with and without inhibition: evidence for a threshold mechanism in motor control. Percept Psychophys 2002; 64: 148-62.
29. Schlaghecken F, Münchau A, Bloem B, Rothwell JC, Eimer M. Effects of motor and premotor cortex repetitive transcranial magnetic stimulation (rTMS) on reaction times in a masked priming task. Neuroimage 2001; 13: S1252.
30. Swerdlow NR, Geyer MA. Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. [Review]. Schizophr Bull 1998; 24: 285-301.
31. Tsai TT, Lasker A, Zee DS. Visual attention in Huntington's disease: the effect of cueing on saccade latencies and manual reaction times. Neuropsychologia 1995; 33: 1617-26.
32. Tzourio-Mazoyer N, De Schonen S, Crivello F, Reutter B, Aujard Y, Mazoyer B. Neural correlates of woman face processing by 2- month-old infants. Neuroimage 2002; 15: 454-61.
33. Vonsattel JP, DiFiglia M. Huntington disease. [Review]. J Neuropathol Exp Neurol 1998; 57: 369-84.
34. Wiggs CL, Martin A. Properties and mechanisms of perceptual priming. [Review]. Curr Opin Neurobiol 1998; 8: 227-33.