Blockade of CD38 diminishes lipopolysaccharide-induced macrophage classical activation and acute kidney injury involving NF-κB signaling suppression

Cellular Signalling

Volumn 42, Issue , 2018, Pages 249-258

  Shu, Bingyan ^a   Feng, Ye ^a   Gui, Yuan ^a   Lu, Qingmiao ^a   Wei, Wei ^a   Xue, Xian ^a   Sun, Xiaoli ^a   He, Weichun ^a   Yang, Junwei ^a   Dai, Chunsun ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

AKI; CD38; Sepsis

Indexed keywords

CD38 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; QUERCETIN; ADP RIBOSYL CYCLASE/CYCLIC ADP RIBOSE HYDROLASE 1; ANTIOXIDANT; CD38 PROTEIN, MOUSE; MEMBRANE PROTEIN; SMALL INTERFERING RNA;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DRUG TARGETING; INFLAMMATORY CELL; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN CELL; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KIDNEY; METABOLISM; PATHOLOGY; PERITONEUM MACROPHAGE; PRIMARY CELL CULTURE; RAW 264.7 CELL LINE; SEPSIS; SPLEEN;

ACUTE KIDNEY INJURY; ADP-RIBOSYL CYCLASE 1; ANIMALS; ANTIOXIDANTS; GENE EXPRESSION REGULATION; KIDNEY; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; NF-KAPPA B; PRIMARY CELL CULTURE; QUERCETIN; RAW 264.7 CELLS; RNA, SMALL INTERFERING; SEPSIS; SIGNAL TRANSDUCTION; SPLEEN;

EID: 85033407883     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2017.10.014     Document Type: Article

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