Monoclonal antibodies targeting CD38 in hematological malignancies and beyond

Immunological Reviews

Volumn 270, Issue 1, 2016, Pages 95-112

  van de Donk, Niels W C J ^a   Janmaat, Maarten L ^b   Mutis, Tuna ^a   Lammerts van Bueren, Jeroen J ^b   Ahmadi, Tahamtan ^c   Sasser, A Kate ^c   Lokhorst, Henk M ^a   Parren, Paul W H I ^b,d,e  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b GENMAB   (Netherlands)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^d UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cancer; CD38; Daratumumab; Isatuximab; Multiple myeloma; Therapeutic antibody

Indexed keywords

ANTINEOPLASTIC AGENT; BORTEZOMIB; CARFILZOMIB; CD38 ANTIBODY AB19; CD38 ANTIBODY AB79; CD38 ANTIGEN; DARATUMUMAB; DEXAMETHASONE; EPITOPE; ISATUXIMAB; LENALIDOMIDE; LIRILUMAB; MELPHALAN; MONOCLONAL ANTIBODY; MOR 202; MT 4019; POMALIDOMIDE; PREDNISONE; PROTEASOME INHIBITOR; RECOMBINANT HYALURONIDASE; RETINOIC ACID; THALIDOMIDE; UNCLASSIFIED DRUG; PROTEIN BINDING;

ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; AGGRESSIVE NK CELL LEUKEMIA; AMYLOIDOSIS; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIGEN BINDING; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AUTOIMMUNE DISEASE; BONE MARROW DERIVED MONONUCLEAR CELL; BURKITT LYMPHOMA; CANCER COMBINATION CHEMOTHERAPY; CHRONIC LYMPHATIC LEUKEMIA; COMPLEMENT DEPENDENT CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME REGULATION; FOLLICULAR LYMPHOMA; HEALTH CARE QUALITY; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOGENETICS; IMMUNOMODULATION; LARGE CELL LYMPHOMA; MANTLE CELL LYMPHOMA; MULTIPLE MYELOMA; NEOPLASM; NK T CELL LYMPHOMA; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHODGKIN LYMPHOMA; OSTEOPOROSIS; PHAGOCYTOSIS; PLASMA CELL LEUKEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; PROTEIN TARGETING; REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS; TISSUE DISTRIBUTION; TUMOR CELL DESTRUCTION; WALDENSTROEM MACROGLOBULINEMIA; ANIMAL; ANTAGONISTS AND INHIBITORS; CLINICAL STUDY; CYTOTOXICITY; DRUG EFFECTS; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; HEMATOLOGIC NEOPLASMS; IMMUNOLOGY; METABOLISM; PRECLINICAL STUDY; RECURRENT DISEASE; TREATMENT OUTCOME;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIGENS, CD38; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CLINICAL STUDIES AS TOPIC; CYTOTOXICITY, IMMUNOLOGIC; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HEMATOLOGIC NEOPLASMS; HUMANS; IMMUNOMODULATION; PROTEIN BINDING; RECURRENCE; TREATMENT OUTCOME;

EID: 84957638157     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12389     Document Type: Review

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