-
1
-
-
84860338675
-
R loops: From transcription byproducts to threats to genome stability
-
Aguilera A, Garcia-Muse T (2012) R loops: from transcription byproducts to threats to genome stability. Mol Cell 46(2):115–124
-
(2012)
Mol Cell
, vol.46
, Issue.2
, pp. 115-124
-
-
Aguilera, A.1
Garcia-Muse, T.2
-
2
-
-
0037650190
-
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
-
Yu K, Chedin F, Hsieh CL, Wilson TE, Lieber MR (2003) R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nat Immunol 4(5):442–451
-
(2003)
Nat Immunol
, vol.4
, Issue.5
, pp. 442-451
-
-
Yu, K.1
Chedin, F.2
Hsieh, C.L.3
Wilson, T.E.4
Lieber, M.R.5
-
3
-
-
0141819093
-
Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination
-
Huertas P, Aguilera A (2003) Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination. Mol Cell 12(3):711–721
-
(2003)
Mol Cell
, vol.12
, Issue.3
, pp. 711-721
-
-
Huertas, P.1
Aguilera, A.2
-
4
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E (2012) A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337 (6096):816–821
-
(2012)
Science
, vol.337
, Issue.6096
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
5
-
-
84964827938
-
Excess of Yra1 RNA-binding factor causes transcription-dependent genome instability, replication impairment and telomere shortening
-
Gavalda S, Santos-Pereira JM, Garcia-Rubio ML, Luna R, Aguilera A (2016) Excess of Yra1 RNA-binding factor causes transcription-dependent genome instability, replication impairment and telomere shortening. PLoS Genet 12(4):e1005966
-
(2016)
Plos Genet
, vol.12
, Issue.4
-
-
Gavalda, S.1
Santos-Pereira, J.M.2
Garcia-Rubio, M.L.3
Luna, R.4
Aguilera, A.5
-
6
-
-
0022516464
-
Characterization of monoclonal antibody to DNA.RNA and its application to immunodetection of hybrids
-
Boguslawski SJ, Smith DE, Michalak MA, Mickelson KE, Yehle CO, Patterson WL, Carrico RJ (1986) Characterization of monoclonal antibody to DNA.RNA and its application to immunodetection of hybrids. J Immunol Methods 89(1):123–130
-
(1986)
J Immunol Methods
, vol.89
, Issue.1
, pp. 123-130
-
-
Boguslawski, S.J.1
Smith, D.E.2
Michalak, M.A.3
Mickelson, K.E.4
Yehle, C.O.5
Patterson, W.L.6
Carrico, R.J.7
-
7
-
-
77954841539
-
Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis
-
El Hage A, French SL, Beyer AL, Tollervey D (2010) Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev 24 (14):1546–1558
-
(2010)
Genes Dev
, vol.24
, Issue.14
, pp. 1546-1558
-
-
El Hage, A.1
French, S.L.2
Beyer, A.L.3
Tollervey, D.4
-
8
-
-
77950473394
-
Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid
-
Pohjoismäki JLO, Holmes JB, Wood SR, Yang M-Y, Yasukawa T, Reyes A, Bailey LJ, Cluett TJ, Goffart S, Willcox S, Rigby RE, Jackson AP, Spelbrink JN, Griffith JD, Crouch RJ, Jacobs HT, Holt IJ (2010) Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid. J Mol Biol 397 (5):1144–1155
-
(2010)
J Mol Biol
, vol.397
, Issue.5
, pp. 1144-1155
-
-
Pohjoismäki, J.L.O.1
Holmes, J.B.2
Wood, S.R.3
Yang, M.-Y.4
Yasukawa, T.5
Reyes, A.6
Bailey, L.J.7
Cluett, T.J.8
Goffart, S.9
Willcox, S.10
Rigby, R.E.11
Jackson, A.P.12
Spelbrink, J.N.13
Griffith, J.D.14
Crouch, R.J.15
Jacobs, H.T.16
Holt, I.J.17
-
9
-
-
78650727733
-
Yeast Sen1 helicase protects the genome from transcription-associated instability
-
Mischo HE, Gómez-González B, Grzechnik P, Rondón AG, Wei W, Steinmetz L, Aguilera A, Proudfoot NJ (2011) Yeast Sen1 helicase protects the genome from transcription-associated instability. Mol Cell 41(1):21–32
-
(2011)
Mol Cell
, vol.41
, Issue.1
, pp. 21-32
-
-
Mischo, H.E.1
Gómez-González, B.2
Grzechnik, P.3
Rondón, A.G.4
Wei, W.5
Steinmetz, L.6
Aguilera, A.7
Proudfoot, N.J.8
-
10
-
-
84255177502
-
RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability
-
Wahba L, Amon JD, Koshland D, Vuica-Ross M (2011) RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability. Mol Cell 44(6):978–988
-
(2011)
Mol Cell
, vol.44
, Issue.6
, pp. 978-988
-
-
Wahba, L.1
Amon, J.D.2
Koshland, D.3
Vuica-Ross, M.4
-
11
-
-
84856253456
-
R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants
-
Stirling PC, Chan YA, Minaker SW, Aristizabal MJ, Barrett I, Sipahimalani P, Kobor MS, Hieter P (2012) R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants. Genes Dev 26(2):163–175
-
(2012)
Genes Dev
, vol.26
, Issue.2
, pp. 163-175
-
-
Stirling, P.C.1
Chan, Y.A.2
Minaker, S.W.3
Aristizabal, M.J.4
Barrett, I.5
Sipahimalani, P.6
Kobor, M.S.7
Hieter, P.8
-
12
-
-
34347218988
-
Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex
-
Gómez-González B, Aguilera A (2007) Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex. Proc Natl Acad Sci U S A 104 (20):8409–8414
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.20
, pp. 8409-8414
-
-
Gómez-González, B.1
Aguilera, A.2
-
13
-
-
84974623814
-
S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation
-
Wahba L, Costantino L, Tan FJ, Zimmer A, Koshland D (2016) S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation. Genes Dev 30 (11):1327–1338
-
(2016)
Genes Dev
, vol.30
, Issue.11
, pp. 1327-1338
-
-
Wahba, L.1
Costantino, L.2
Tan, F.J.3
Zimmer, A.4
Koshland, D.5
-
14
-
-
84859087611
-
R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters
-
Ginno PA, Lott PL, Christensen HC, Korf I, Chédin F (2012) R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters. Mol Cell 45(6):814–825
-
(2012)
Mol Cell
, vol.45
, Issue.6
, pp. 814-825
-
-
Ginno, P.A.1
Lott, P.L.2
Christensen, H.C.3
Korf, I.4
Chédin, F.5
-
15
-
-
84918791689
-
Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability
-
Sollier J, Stork CT, García-Rubio ML, Paulsen RD, Aguilera A, Cimprich KA (2014) Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability. Mol Cell 56(6):777–785
-
(2014)
Mol Cell
, vol.56
, Issue.6
, pp. 777-785
-
-
Sollier, J.1
Stork, C.T.2
García-Rubio, M.L.3
Paulsen, R.D.4
Aguilera, A.5
Cimprich, K.A.6
-
16
-
-
84949256749
-
The Fanconi Anemia Pathway Protects Genome Integrity from R-loops
-
Garcia-Rubio ML, Perez-Calero C, Barroso SI, Tumini E, Herrera-Moyano E, Rosado IV, Aguilera A (2015) The Fanconi Anemia Pathway Protects Genome Integrity from R-loops. PLoS Genet 11(11):e1005674
-
(2015)
Plos Genet
, vol.11
, Issue.11
-
-
Garcia-Rubio, M.L.1
Perez-Calero, C.2
Barroso, S.I.3
Tumini, E.4
Herrera-Moyano, E.5
Rosado, I.V.6
Aguilera, A.7
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