The E2A splice variant E47 regulates the differentiation of projection neurons via p57(KIP2) during cortical development

Development (Cambridge)

Volumn 144, Issue 21, 2017, Pages 3917-3931

  Pfurr, Sabrina ^a,b   Chu, Yu Hsuan ^a,b   Bohrer, Christian ^a,b   Greulich, Franziska ^c   Beattie, Robert ^d,f   Mammadzada, Könül ^a,b   Hils, Miriam ^b,e   Arnold, Sebastian J ^a,b   Taylor, Verdon ^d   Schachtrup, Kristina ^b,e   Henriette Uhlenhaut, N ^c   Schachtrup, Christian ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d UNIVERSITY OF BASEL   (Switzerland)

^e UNIVERSITY OF FREIBURG   (Germany)

^f INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA   (Austria)

Author keywords

Basic helix loop helix transcription factor; Cell cycle regulation; Cortical neurogenesis; E2A; Enhancer; Neurite outgrowth; P57(KIP2)

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1C; DNA; E47 PROTEIN; HETERODIMER; HOMODIMER; MESSENGER RNA; TRANSCRIPTION FACTOR E2A; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CDKN1C PROTEIN, MOUSE; PROTEIN BINDING; TCF3 PROTEIN, MOUSE; TRANSCRIPTION FACTOR 3;

ANIMAL CELL; ANTIBODY LABELING; ANTIBODY SPECIFICITY; APOPTOSIS; ARTICLE; BINDING SITE; BRAIN CORTEX; BRAIN DEVELOPMENT; CELL ADHESION; CELL CYCLE PROGRESSION; CELL SIZE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA BINDING; DNA SEQUENCE; ELECTROPORATION; EMBRYO; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENE LOCUS; IMMUNOPRECIPITATION; IN VITRO STUDY; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURITE OUTGROWTH; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEPLETION; QUANTITATIVE ANALYSIS; RNA HYBRIDIZATION; RNA SEQUENCE; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING; ALTERNATIVE RNA SPLICING; ANIMAL; C57BL MOUSE; CELL CYCLE; CELL DIFFERENTIATION; CHROMATIN; CYTOLOGY; DEFICIENCY; EMBRYOLOGY; ENHANCER REGION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NERVE CELL; NEURAL STEM CELL; NUCLEOTIDE SEQUENCE;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; CELL CYCLE; CELL DIFFERENTIATION; CEREBRAL CORTEX; CHROMATIN; CYCLIN-DEPENDENT KINASE INHIBITOR P57; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE, INBRED C57BL; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; PROTEIN BINDING; TRANSCRIPTION FACTOR 3; TRANSCRIPTION, GENETIC;

EID: 85032785926     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.145698     Document Type: Article

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