Intra-arterial verapamil post-thrombectomy is feasible, safe, and neuroprotective in stroke

Journal of Cerebral Blood Flow and Metabolism

Volumn 37, Issue 11, 2017, Pages 3531-3543

  Fraser, Justin F ^a   Maniskas, Michael ^a   Trout, Amanda ^a   Lukins, Doug ^a   Parker, Lindsey ^a   Stafford, W Lane ^a   Alhajeri, Abdulnasser ^a   Roberts, Jill ^a   Bix, Gregory J ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

emergent large vessel occlusion; Ischemic stroke; neuroprotection; thrombectomy; verapamil

Indexed keywords

VERAPAMIL; ANTIARRHYTHMIC AGENT; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ARTICLE; BRAIN CELL; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL SURVIVAL; CEREBROVASCULAR ACCIDENT; CLINICAL OUTCOME; CONTROLLED STUDY; CORONARY ARTERY RECANALIZATION; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; IMMUNOHISTOCHEMISTRY; LD50; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEURITE OUTGROWTH; NEUROPROTECTION; NONHUMAN; PERCUTANEOUS THROMBECTOMY; PRIORITY JOURNAL; RECANALIZATION; THROMBECTOMY; ADULT; AGED; ANIMAL; BRAIN HYPOXIA; C57BL MOUSE; CELL CULTURE; CELL DEATH; CLINICAL TRIAL; DRUG EFFECTS; FEMALE; HUMAN; INTRAARTERIAL DRUG ADMINISTRATION; MIDDLE AGED; NEURITE; PATHOLOGY; PHASE 1 CLINICAL TRIAL; PRIMARY CELL CULTURE; TREATMENT OUTCOME; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTI-ARRHYTHMIA AGENTS; BRAIN ISCHEMIA; CELL DEATH; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; HYPOXIA, BRAIN; INJECTIONS, INTRA-ARTERIAL; MALE; MICE, INBRED C57BL; MIDDLE AGED; NEURITES; NEUROPROTECTIVE AGENTS; PRIMARY CELL CULTURE; STROKE; THROMBECTOMY; TREATMENT OUTCOME; VERAPAMIL;

EID: 85032720291     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1177/0271678X17705259     Document Type: Article

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