Selective intra-arterial drug administration in a model of large vessel ischemia

Journal of Neuroscience Methods

Volumn 240, Issue , 2015, Pages 22-27

  Maniskas, Michael ^a   Bix, Gregory ^a   Fraser, Justin ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Endovascular thrombectomy; Intra arterial; Recanalization; Stroke

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BRAIN BLOOD FLOW; BRAIN CIRCULATION; BRAIN ISCHEMIA; CAROTID ARTERY BIFURCATION; DRUG DELIVERY SYSTEM; EXPERIMENTAL MODEL; FLOW RATE; INTRAARTERIAL DRUG ADMINISTRATION; INTRAVASCULAR CATHETER; LARGE VESSEL ISCHEMIC STROKE; LASER DOPPLER FLOWMETRY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; NYLON SUTURE; PERCUTANEOUS THROMBECTOMY; RECANALIZATION; REPERFUSION; ANIMAL; BLOOD VESSEL PROSTHESIS; BRAIN; C57BL MOUSE; COMMON CAROTID ARTERY; DEVICES; DISEASE MODEL; DRUG EFFECTS; ECHOGRAPHY; ENDOVASCULAR SURGERY; FEASIBILITY STUDY; FIBRINOLYTIC THERAPY; MIDDLE CEREBRAL ARTERY; NEUROSURGERY; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; STROKE; SURGERY;

ANIMALS; BLOOD VESSEL PROSTHESIS; BRAIN; BRAIN ISCHEMIA; CAROTID ARTERY, COMMON; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; ENDOVASCULAR PROCEDURES; FEASIBILITY STUDIES; INJECTIONS, INTRA-ARTERIAL; LASER-DOPPLER FLOWMETRY; MICE, INBRED C57BL; MIDDLE CEREBRAL ARTERY; NEUROSURGICAL PROCEDURES; STROKE; THROMBOLYTIC THERAPY;

EID: 84911888792     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2014.10.015     Document Type: Article

References (12)

1. Aronowski J., Cho K.H., Strong R., Grotta J.C. Neurofilament proteolysis after focal ischemia; when do cells die after experimental stroke?. J Cereb Blood Flow Metab: Off J Int Soc Cereb Blood Flow Metab 1999, 19:652-660.
2. Broderick J.P., Palesch Y.Y., Demchuk A.M., Yeatts S.D., Khatri P., Hill M.D., et al. Interventional management of stroke IIII (2013) endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med 2013, 368:893-903.
3. Chen L., Swartz K.R., Toborek M. Vessel microport technique for applications in cerebrovascular research. J Neurosci Res 2009, 87:1718-1727.
4. Fargen K.M., Meyers P.M., Khatri P., Mocco J. Improvements in recanalization with modern stroke therapy: a review of prospective ischemic stroke trials during the last two decades. J Neurointerv Surg 2013, 5:506-511.
5. Hasan M.R., Herz J., Hermann D.M., Doeppner T.R. Visualization of macroscopic cerebral vessel anatomy - a new and reliable technique in mice. J Neurosci Methods 2012, 204:249-253.
6. Investigators IIT The interventional management of stroke (IMS) II study. Stroke: J Cereb Circ 2007, 38:2127-2135.
7. Lee B., Clarke D., Al Ahmad A., Kahle M., Parham C., Auckland L., et al. Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents. J Clin Invest 2011, 121:3005-3023.
8. Lees K.R., Zivin J.A., Ashwood T., Davalos A., Davis S.M., Diener H.C., et al. Stroke-acute ischemic NXYTTI (2006) NXY-059 for acute ischemic stroke. N Engl J Med 2006, 354:588-600.
9. Lichtman J.H., Watanabe E., Allen N.B., Jones S.B., Dostal J., Goldstein L.B. Hospital arrival time and intravenous t-PA use in US Academic Medical Centers, 2001-2004. Stroke: J Cereb Circ 2009, 40:3845-3850.
10. Saver J.L., Jahan R., Levy E.I., Jovin T.G., Baxter B., Nogueira R.G., et al. Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial. Lancet 2012, 380:1241-1249.
11. Savitz S.I. A critical appraisal of the NXY-059 neuroprotection studies for acute stroke: a need for more rigorous testing of neuroprotective agents in animal models of stroke. Exp Neurol 2007, 205:20-25.
12. Van Winkle J.A., Chen B., Lei I.F., Pereira B., Rajput P.S., Lyden P.D. Concurrent middle cerebral artery occlusion and intra-arterial drug infusion via ipsilateral common carotid artery catheter in the rat. J Neurosci Methods 2013, 213:63-69.