Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 43, 2017, Pages E9026-E9035

  Couce, Alejandro ^a   Caudwell, Larissa Viraphong ^b   Feinauer, Christoph ^d   Hindré, Thomas ^b   Feugeas, Jean Paul ^a   Weigt, Martin ^c   Lenski, Richard E ^d,e   Schneider, Dominique ^b   Tenaillon, Olivier ^a  

^a UNIVERSITÉ PARIS DIDEROT   (France)

^b UNIV GRENOBLE ALPES   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d Michigan State University ^*  (United States)

^e MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Experimental evolution; GC content; Genetic draft; Hypermutability; Selection

Indexed keywords

MUTAGENIC AGENT;

ALLELE; ARTICLE; BACTERIAL GENOME; ESCHERICHIA COLI; GENE MUTATION; LOSS OF FUNCTION MUTATION; MUTATION ACCUMULATION; MUTATION RATE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; GENETIC SELECTION; GENETICS; MOLECULAR EVOLUTION; MUTATION; PHYLOGENY; PHYSIOLOGY;

ESCHERICHIA COLI; EVOLUTION, MOLECULAR; GENOME, BACTERIAL; MUTATION; MUTATION RATE; PHYLOGENY; SELECTION, GENETIC;

EID: 85032181011     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1705887114     Document Type: Article

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