Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

Cell Reports

Volumn 21, Issue 3, 2017, Pages 679-691

  Fernández, Esperanza ^a,j,m   Collins, Mark O ^a,l   Frank, René A W ^a,b   Zhu, Fei ^a,c   Kopanitsa, Maksym V ^a,d,n   Nithianantharajah, Jess ^a,c   Lemprière, Sarah A ^c   Fricker, David ^a,d   Elsegood, Kathryn A ^a,c   McLaughlin, Catherine L ^c   Croning, Mike D R ^c   Mclean, Colin ^e   Armstrong, J Douglas ^e   Hill, W David ^e   Deary, Ian J ^e   Cencelli, Giulia ^j,k   Bagni, Claudia ^j,k,o   Fromer, Menachem ^f,g,h   Purcell, Shaun M ^h   Pocklington, Andrew J ⁱ   Choudhary, Jyoti S ^a   Komiyama, Noboru H ^a,c   Grant, Seth G N ^a,c   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d Synomics Ltd   (United Kingdom)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^h MOUNT SINAI SCHOOL OF MEDICINE   (United States)

ⁱ CARDIFF UNIVERSITY   (United Kingdom)

^j UNIVERSITY OF LEUVEN   (Belgium)

^k UNIVERSITY OF ROME TOR VERGATA   (Italy)

^l UNIVERSITY OF SHEFFIELD   (United Kingdom)

^m GHENT UNIVERSITY   (Belgium)

ⁿ Charles River Discovery Research Services   (Finland)

^o UNIVERSITY OF LAUSANNE   (Switzerland)

more..

Author keywords

Arc; cognition; genetic variants; intellectual disability; PSD95; schizophrenia; supercomplexes; synaptic complexes; tandem affinity purification

Indexed keywords

CYTOSKELETON PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN ARC; UNCLASSIFIED DRUG; ACTIVITY REGULATED CYTOSKELETAL-ASSOCIATED PROTEIN; DISKS LARGE HOMOLOG 4; DLG4 PROTEIN, MOUSE; NERVE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN TISSUE; COGNITION; EPILEPSY; HUMAN; INTELLECTUAL IMPAIRMENT; INTELLIGENCE; KNOCKOUT MOUSE; MALE; MOUSE; NEURAL DYSFUNCTION; NEUROLOGIC DISEASE; NONHUMAN; PHENOTYPE; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEOMICS; SCHIZOPHRENIA; SYNAPSE; WILD TYPE; ANIMAL; GENE KNOCK-IN; METABOLISM; NERVOUS SYSTEM; PATHOPHYSIOLOGY;

ANIMALS; CYTOSKELETAL PROTEINS; DISKS LARGE HOMOLOG 4 PROTEIN; GENE KNOCK-IN TECHNIQUES; HUMANS; INTELLIGENCE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NERVOUS SYSTEM; PROTEOMICS; SYNAPSES;

EID: 85032003354     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.09.045     Document Type: Article

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