Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA

Immunity

Volumn 47, Issue 3, 2017, Pages 435-449.e8

  Mowel, Walter K ^a,b   McCright, Sam J ^a,b   Kotzin, Jonathan J ^a,b   Collet, Magalie A ^c   Uyar, Asli ^c   Chen, Xin ^c,d   DeLaney, Alexandra ^a   Spencer, Sean P ^a,b   Virtue, Anthony T ^a,b   Yang, EnJun ^a,b   Villarino, Alejandro ^e   Kurachi, Makoto ^b   Dunagin, Margaret C ^f   Pritchard, Gretchen Harms ^a   Stein, Judith ^g,h   Hughes, Cynthia ^g,h   Fonseca Pereira, Diogo ⁱ   Veiga Fernandes, Henrique ^i,j   Raj, Arjun ^f   Kambayashi, Taku ^a,b   Brodsky, Igor E ^a   O'Shea, John J ^e   Wherry, E John ^b   Goff, Loyal A ^k,l   Rinn, John L ^m,n   Williams, Adam ^c,o   Flavell, Richard A ^f,g   Henao Mejia, Jorge ^a,b   more..

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c JACKSON LABORATORY   (United States)

^d UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^e NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h YALE UNIVERSITY   (United States)

ⁱ INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^j CHAMPALIMAUD CENTRE FOR THE UNKNOWN   (Portugal)

^k JOHNS HOPKINS UNIVERSITY   (United States)

^l JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^m HARVARD MEDICAL SCHOOL   (United States)

ⁿ Harvard University   (United States)

^o UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

more..

Author keywords

Id2; ILC1; innate lymphoid cells; lineage identity; lncRNA; transcriptional regulation

Indexed keywords

INHIBITOR OF DIFFERENTIATION 2; INTERLEUKIN 15; LONG UNTRANSLATED RNA; STAT5 PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINEAGE; CELL MATURATION; CHROMATIN; GENE EXPRESSION; GENE LOCUS; HOMEOSTASIS; LYMPHOID CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY SEQUENCE; RROID GENE; ANIMAL; CELL DIFFERENTIATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CYTOLOGY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; LYMPHOCYTE; LYMPHOCYTE SUBPOPULATION; MALE; METABOLISM; NATURAL KILLER CELL;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CHROMATIN ASSEMBLY AND DISASSEMBLY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC LOCI; HOMEOSTASIS; IMMUNITY, INNATE; INHIBITOR OF DIFFERENTIATION PROTEIN 2; KILLER CELLS, NATURAL; LYMPHOCYTE SUBSETS; LYMPHOCYTES; MALE; MICE; PROMOTER REGIONS, GENETIC; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, LONG NONCODING; STAT5 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC;

EID: 85031753412     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.08.012     Document Type: Article

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