Innovation in microbiome-based strategies for promoting metabolic health

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 20, Issue 6, 2017, Pages 484-491

  Romaní Pérez, Marina ^a   Agusti, Ana ^a   Sanz, Yolanda ^a  

^a INSTITUTO DE AGROQUÍMICA Y TECNOLOGÍA DE ALIMENTOS CSIC   (Spain)

Author keywords

comorbidities; gut microbiota; microbiota replacement; next generation probiotics; obesity

Indexed keywords

PROBIOTIC AGENT; MEMBRANE PROTEIN; VOLATILE FATTY ACID;

ABSORPTION; BACTEROIDES; CALORIC INTAKE; CLINICAL TRIAL (TOPIC); COMORBIDITY; DIET SUPPLEMENTATION; DIETARY SUPPLEMENT; ENERGY EXPENDITURE; EUBACTERIUM; HEALTH PROMOTION; HUMAN; METABOLISM; MICROBIOME; MICROFLORA; MORTALITY; OBESITY; REVIEW; ANIMAL; DIET; DISEASE MANAGEMENT; DISEASE MODEL; GASTROINTESTINAL TRACT; INTESTINE FLORA; MICROBIOLOGY;

ANIMALS; BACTEROIDES; DIET; DISEASE MANAGEMENT; DISEASE MODELS, ANIMAL; EUBACTERIUM; FATTY ACIDS, VOLATILE; GASTROINTESTINAL MICROBIOME; GASTROINTESTINAL TRACT; HUMANS; MEMBRANE PROTEINS; OBESITY; PROBIOTICS;

EID: 85030774594     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0000000000000419     Document Type: Review

References (42)

1. Roberto CA, Swinburn B, Hawkes C, et al. Patchy progress on obesity prevention: emerging examples, entrenched barriers, and new thinking. Lancet 2015; 385:2400-2409.
2. Doulberis M, Kotronis G, Gialamprinou D, et al. Nonalcoholic fatty liver disease: an update with special focus on the role of gut microbiota. Metabolism 2017; 71:182-197.
3. Sonnenburg JL, Bäckhed F. Diet-microbiota interactions as moderators of human metabolism. Nature 2016; 535:56-64.
4. Dahiya DK, Renuka. Puniya M, et al. Gut microbiota modulation and its relationship with obesity using prebiotic fibers and probiotics: a review. Front Microbiol 2017; 8:563.
5. Li J, Zhao F, Wang Y, et al. Gut microbiota dysbiosis contributes to the development of hypertension. Microbiome 2017; 5:14.
6. Ridaura VK, Faith JJ, Rey FE, et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 2013; 341:1241214.
7. Bentez-Paez A, Sanz Y. Multi-locus and long amplicon sequencing approach to study microbial diversity at species level using the MinIONTM portable nanopore sequencer. GigaScience 2017; 6:1-12.
8. Xiao L, Estelle J, Kiilerich P, et al. A reference gene catalogue of the pig gut microbiome. Nat Microbiol 2016; 1:1-6.
9. Chapman BC, Moore HB, Overbey DM, et al. Fecal microbiota transplant in patients with Clostridium difficile infection: a systematic review. J Trauma Acute Care Surg 2016; 81:756-764.
10. Choi HH, Cho Y-S. Fecal microbiota transplantation: current applications, effectiveness, and future perspectives. Clin Endosc 2016; 49:257-265.
11. Carlucci C, Petrof EO, Allen-Vercoe E. Fecal microbiota-based therapeutics for recurrent Clostridium difficile infection, ulcerative colitis and obesity. EBioMedicine 2016; 13:37-45.
12. Marotz CA, Zarrinpar A. Treating obesity and metabolic syndrome with fecal microbiota transplantation. Yale J Biol Med 2016; 89:383-388.
13. de Vos WM. Microbe profile: Akkermansia muciniphila: a conserved intestinal symbiont that acts as the gatekeeper of our mucosa. Microbiol Read Engl 2017; 163:646-648.
14. Derrien M, Belzer C, de Vos WM. Akkermansia muciniphila and its role in regulating host functions. Microb Pathog 2017; 106:171-181.
15. Dao MC, Everard A, Aron-Wisnewsky J, et al. Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology. Gut 2016; 65:426-436.
16. Schneeberger M, Everard A, Gomez-Valades AG, et al. Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice. Sci Rep 2015; 5:16643.
17. Everard A, Belzer C, Geurts L, et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci U S A 2013; 110:9066-9071.
18. Plovier H, Everard A, Druart C, et al. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nat Med 2017; 23:107-113.
19. Greer RL, Dong X, Moraes AC, et al. Akkermansia muciniphila mediates negative effects of IFNg on glucose metabolism. Nat Commun 2016; 7:13329.
20. Sanz Y, Olivares M, Moya-Perez A , Agostoni C. Understanding the role of gut microbiome in metabolic disease risk. Pediatr Res 2015; 77(1-2): 236-244.
21. Andoh A, Nishida A, Takahashi K, et al. Comparison of the gut microbial community between obese and lean peoples using 16S gene sequencing in a Japanese population. J Clin Biochem Nutr 2016; 59:65-70.
22. Wang J, Jia H. Metagenome-wide association studies: fine-mining the microbiome. Nat Rev Microbiol 2016; 14:508-522.
23. De Filippis F, Pellegrini N, Laghi L, et al. Unusual sub-genus associations of faecal Prevotella and Bacteroides with specific dietary patterns. Microbiome 2016; 4:57.
24. Simpson HL, Campbell BJ. Review article: dietary fibre-microbiota interactions. Aliment Pharmacol Ther 2015; 42:158-179.
25. Heinritz SN, Weiss E, Eklund M, et al. Impact of a high-fat or high-fiber diet on intestinal microbiota and metabolic markers in a pig model. Nutrients 2016; 8:1-16.
26. Macpherson AJ, Kö ller Y, McCoy KD. The bilateral responsiveness between intestinal microbes and IgA. Trends Immunol 2015; 36:460-470.
27. Steimle A, Frick J-S. Molecular mechanisms of induction of tolerant and tolerogenic intestinal dendritic cells in mice. J Immunol Res 2016; 2016: 1958650.
28. Sanz Y, Moya-Perez A. Microbiota, inflammation and obesity. Adv Exp Med Biol 2014; 817:291-317.
29. Fernández-Murga ML, Sanz Y. Safety assessment of Bacteroides uniformis CECT 7771 isolated from stools of healthy breast-fed infants. PLoS One 2016; 11:e0145503.
30. Yang J-Y, Lee Y-S, Kim Y, et al. Gut commensal Bacteroides acidifaciens prevents obesity and improves insulin sensitivity in mice. Mucosal Immunol 2017; 10:104-116.
31. Udayappan S, Manneras-Holm L, Chaplin-Scott A, et al. Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice. NPJ Biofilms Microbiomes 2016; 2:16009.
32. de Clercq N, Frissen MN, Groen AK, Nieuwdorp M. Gut microbiota and the gut-brain axis: new insights in the pathophysiology of metabolic syndrome. Psychosom Med 2017; in press. doi: 10.1097/PSY.0000000000000495.
33. Husted AS, Trauelsen M, Rudenko O, et al. GPCR-mediated signaling of metabolites. Cell Metab 2017; 25:777-796.
34. Psichas A, Reimann F, Gribble FM. Gut chemosensing mechanisms. J Clin Invest 2015; 125:908-917;
35. Byrne CS, Chambers ES, Morrison DJ, Frost G. The role of short chain fatty acids in appetite regulation and energy homeostasis. Int J Obes 2015; 39:1331-1338.
36. Greiner TU, Bäckhed F. Microbial regulation of GLP-1 and L-cell biology. Mol Metab 2016; 5:753-758.
37. Chambers ES, Viardot A, Psichas A, et al. Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults. Gut 2015; 64:1744-1754.
38. Pingitore A, Chambers ES, Hill T, et al. The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro. Diabetes Obes Metab 2017; 19:257-265.
39. Weitkunat K, Stuhlmann C, Postel A, et al. Short-chain fatty acids and inulin, but not guar gum, prevent diet-induced obesity and insulin resistance through differential mechanisms in mice. Sci Rep 2017; 7:6109.
40. Chá vez-Talavera O, Tailleux A, Lefebvre P, Staels B. Bile acid control of metabolism and inflammation in obesity, type 2 diabetes, dyslipidemia, and nonalcoholic fatty liver disease. Gastroenterology 2017; 152:1679-1694; e3.
41. Tremaroli V, Karlsson F, Werling M, et al. Roux-en-Y gastric bypass and vertical banded gastroplasty induce long-term changes on the human gut microbiome contributing to fat mass regulation. Cell Metab 2015; 22:228-238.
42. Somm E, Henry H, Bruce SJ, et al. b-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue. JCI Insight 2017; 2:56.