-
1
-
-
78149373656
-
Projection of the year 2050 burden of diabetes in the US adult population: Dynamic modeling of incidence, mortality, and, prediabetes prevalence
-
Boyle, J. P., Thompson, T. J., Gregg, E. W., Barker, L. E. & Williamson, D. F. Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalence. Popul. Health Metr. 8, 29 (2010).
-
(2010)
Popul. Health Metr
, vol.8
, pp. 29
-
-
Boyle, J.P.1
Thompson, T.J.2
Gregg, E.W.3
Barker, L.E.4
Williamson, D.F.5
-
2
-
-
84910131419
-
Microbial modulation of insulin sensitivity
-
Khan, M. T., Nieuwdorp, M. & Backhed, F. Microbial modulation of insulin sensitivity. Cell Metab. 20, 753-760 (2014).
-
(2014)
Cell Metab
, vol.20
, pp. 753-760
-
-
Khan, M.T.1
Nieuwdorp, M.2
Backhed, F.3
-
3
-
-
84878709716
-
Gut metagenome in European women with normal, impaired and diabetic glucose control
-
Karlsson, F. H. et al. Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature 498, 99-103 (2013).
-
(2013)
Nature
, vol.498
, pp. 99-103
-
-
Karlsson, F.H.1
-
4
-
-
84883110880
-
Richness of human gut microbiome correlates with metabolic markers
-
Le Chatelier, E. et al. Richness of human gut microbiome correlates with metabolic markers. Nature 500, 541-546 (2013).
-
(2013)
Nature
, vol.500
, pp. 541-546
-
-
Le Chatelier, E.1
-
5
-
-
67649238355
-
Butyrate improves insulin sensitivity and increases energy expenditure in mice
-
Gao, Z. et al. Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes 58, 1509-1517 (2009).
-
(2009)
Diabetes
, vol.58
, pp. 1509-1517
-
-
Gao, Z.1
-
6
-
-
84883478660
-
Gut microbiota from twins discordant for obesity modulate metabolism in mice
-
Ridaura, V. K. et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 341, 1241214 (2013).
-
(2013)
Science
, vol.341
, pp. 1241214
-
-
Ridaura, V.K.1
-
7
-
-
84866738529
-
Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome
-
Vrieze, A. et al. Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. Gastroenterology 143, 913-916 917 (2012).
-
(2012)
Gastroenterology
, vol.143
, Issue.917
, pp. 913-916
-
-
Vrieze, A.1
-
8
-
-
77649119543
-
Diversity of human colonic butyrate-producing bacteria revealed by analysis of the butyryl-CoA:acetate CoA-Transferase gene
-
Louis, P., Young, P., Holtrop, G. & Flint, H. J. Diversity of human colonic butyrate-producing bacteria revealed by analysis of the butyryl-CoA:acetate CoA-Transferase gene. Environ. Microbiol. 12, 304-314 (2010).
-
(2010)
Environ. Microbiol
, vol.12
, pp. 304-314
-
-
Louis, P.1
Young, P.2
Holtrop, G.3
Flint, H.J.4
-
9
-
-
8144224956
-
Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product
-
Duncan, S. H., Louis, P. & Flint, H. J. Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product. Appl. Environ. Microb. 70, 5810-5817 (2004).
-
(2004)
Appl. Environ. Microb
, vol.70
, pp. 5810-5817
-
-
Duncan, S.H.1
Louis, P.2
Flint, H.J.3
-
10
-
-
79952749979
-
Systemic gut microbial modulation of bile acid metabolism in host tissue compartments
-
Swann, J. R. et al. Systemic gut microbial modulation of bile acid metabolism in host tissue compartments. Proc. Natl Acad. Sci. USA 108, 4523-4530 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 4523-4530
-
-
Swann, J.R.1
-
11
-
-
69449095892
-
Bile acids as regulatory molecules
-
Hylemon, P. B. et al. Bile acids as regulatory molecules. J. Lipid Res. 50, 1509-1520 (2009).
-
(2009)
J. Lipid Res
, vol.50
, pp. 1509-1520
-
-
Hylemon, P.B.1
-
12
-
-
0034664729
-
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
-
Sinal, C. J. et al. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102, 731-744 (2000).
-
(2000)
Cell
, vol.102
, pp. 731-744
-
-
Sinal, C.J.1
-
13
-
-
77953980094
-
Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine
-
Beuling, E. et al. Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine. Gut 59, 888-895 (2010).
-
(2010)
Gut
, vol.59
, pp. 888-895
-
-
Beuling, E.1
-
14
-
-
33745569311
-
Efficacy of an encapsulated probiotic bifidobacterium infantis 35624 in women with irritable bowel syndrome
-
Whorwell, P. J. et al. Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. Am. J. Gastroenterol. 101, 1581-1590 (2006).
-
(2006)
Am. J. Gastroenterol
, vol.101
, pp. 1581-1590
-
-
Whorwell, P.J.1
-
15
-
-
84878465280
-
Cross-Talk between akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
-
Everard, A. et al. Cross-Talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc. Natl Acad. Sci. USA 110, 9066-9071 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 9066-9071
-
-
Everard, A.1
-
16
-
-
84892814749
-
Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits
-
De Vadder, F. et al. Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits. Cell 156, 84-96 (2014).
-
(2014)
Cell
, vol.156
, pp. 84-96
-
-
De Vadder, F.1
-
17
-
-
70849133150
-
Bile acid transporters
-
Dawson, P. A., Lan, T. & Rao, A. Bile acid transporters. J. Lipid Res. 50, 2340-2357 (2009).
-
(2009)
J. Lipid Res
, vol.50
, pp. 2340-2357
-
-
Dawson, P.A.1
Lan, T.2
Rao, A.3
-
18
-
-
70349430938
-
Bile acids: Regulation of synthesis
-
Chiang, J. Y. L. Bile acids: Regulation of synthesis. J. Lipid Res. 50, 1955-1966 (2009).
-
(2009)
J. Lipid Res
, vol.50
, pp. 1955-1966
-
-
Chiang, J.Y.L.1
-
19
-
-
33644941373
-
Bile salt hydrolase activity in probiotics
-
Begley, M., Hill, C. & Gahan, C. G. M. Bile salt hydrolase activity in probiotics. Appl. Environ. Microb. 72, 1729-1738 (2006).
-
(2006)
Appl. Environ. Microb
, vol.72
, pp. 1729-1738
-
-
Begley, M.1
Hill, C.2
Gahan, C.G.M.3
-
20
-
-
84901020405
-
Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut
-
Joyce, S. A. et al. Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut. Proc. Natl Acad. Sci. USA 111, 7421-7426 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 7421-7426
-
-
Joyce, S.A.1
-
21
-
-
84904765600
-
Prednisolone increases enterohepatic cycling of bile acids by induction of Asbt and promotes reverse cholesterol transport
-
Out, C. et al. Prednisolone increases enterohepatic cycling of bile acids by induction of Asbt and promotes reverse cholesterol transport. J. Hepatol. 61, 351-357 (2014).
-
(2014)
J. Hepatol
, vol.61
, pp. 351-357
-
-
Out, C.1
-
22
-
-
73349101418
-
Administration of ampicillin elevates hepatic primary bile acid synthesis through suppression of ileal fibroblast growth factor 15 expression
-
Miyata, M., Takamatsu, Y., Kuribayashi, H. & Yamazoe, Y. Administration of ampicillin elevates hepatic primary bile acid synthesis through suppression of ileal fibroblast growth factor 15 expression. J. Pharmacol. Exp. Ther. 331, 1079-1085 (2009).
-
(2009)
J. Pharmacol. Exp. Ther
, vol.331
, pp. 1079-1085
-
-
Miyata, M.1
Takamatsu, Y.2
Kuribayashi, H.3
Yamazoe, Y.4
-
23
-
-
84887960056
-
Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity
-
Li, F. et al. Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity. Nat. Commun. 4: 2384. (2013).
-
(2013)
Nat. Commun
, vol.4
, pp. 2384
-
-
Li, F.1
-
24
-
-
84898023722
-
Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr-Fgf15 axis in mice
-
Degirolamo, C., Rainaldi, S., Bovenga, F., Murzilli, S. & Moschetta, A. Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr-Fgf15 axis in mice. Cell Rep. 7, 12-18 (2014).
-
(2014)
Cell Rep.
, vol.7
, pp. 12-18
-
-
Degirolamo, C.1
Rainaldi, S.2
Bovenga, F.3
Murzilli, S.4
Moschetta, A.5
-
25
-
-
84925507991
-
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
-
Fang, S. et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nat. Med. 21, 159-165 (2015).
-
(2015)
Nat. Med
, vol.21
, pp. 159-165
-
-
Fang, S.1
-
26
-
-
79953129095
-
FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis
-
Kir, S. et al. FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis. Science 331, 1621-1624 (2011).
-
(2011)
Science
, vol.331
, pp. 1621-1624
-
-
Kir, S.1
-
27
-
-
84878698171
-
GENOMICS: A gut prediction
-
de Vos, W. M. & Nieuwdorp, M. GENOMICS: A gut prediction. Nature 498, 48-49 (2013).
-
(2013)
Nature
, vol.498
, pp. 48-49
-
-
De Vos, W.M.1
Nieuwdorp, M.2
-
28
-
-
84883428628
-
Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet
-
Cansby, E. et al. Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet. FASEB J. 27, 3660-3671 (2013).
-
(2013)
FASEB J
, vol.27
, pp. 3660-3671
-
-
Cansby, E.1
-
29
-
-
63849164050
-
Effect of inulin on the human gut microbiota: Stimulation of bifidobacterium adolescentis and faecalibacterium prausnitzii
-
Ramirez-Farias, C. et al. Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii. Br. J. Nutr. 101, 541-550 (2009).
-
(2009)
Br. J. Nutr
, vol.101
, pp. 541-550
-
-
Ramirez-Farias, C.1
-
30
-
-
67649945513
-
Development and application of the human intestinal tract chip, a phylogenetic microarray: Analysis of universally conserved phylotypes in the abundant microbiota of young and elderly adults
-
Rajilic-Stojanovic, M. et al. Development and application of the human intestinal tract chip, a phylogenetic microarray: Analysis of universally conserved phylotypes in the abundant microbiota of young and elderly adults. Environ. Microbiol. 11, 1736-1751 (2009).
-
(2009)
Environ. Microbiol.
, vol.11
, pp. 1736-1751
-
-
Rajilic-Stojanovic, M.1
-
31
-
-
78449287303
-
Probabilistic analysis of probe reliability in differential gene expression studies with short oligonucleotide arrays
-
Lahti, L., Elo, L. L., Aittokallio, T. & Kaski, S. Probabilistic analysis of probe reliability in differential gene expression studies with short oligonucleotide arrays. IEEE/ACM Trans. Comput. Biol. 8, 217-225 (2011).
-
(2011)
IEEE/ACM Trans. Comput. Biol
, vol.8
, pp. 217-225
-
-
Lahti, L.1
Elo, L.L.2
Aittokallio, T.3
Kaski, S.4
-
33
-
-
84873342775
-
Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
-
Sayin, S. I. et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metab. 17, 225-235 (2013).
-
(2013)
Cell Metab
, vol.17
, pp. 225-235
-
-
Sayin, S.I.1
|