Nuclear import inhibitor N-(4-hydroxyphenyl) retinamide targets Zika virus (ZIKV) nonstructural protein 5 to inhibit ZIKV infection

Biochemical and Biophysical Research Communications

Volumn 493, Issue 4, 2017, Pages 1555-1559

  Wang, Chunxiao ^a   Yang, Sundy N Y ^a   Smith, Kate ^b   Forwood, Jade K ^b   Jans, David A ^a  

^a MONASH UNIVERSITY   (Australia)

^b CHARLES STURT UNIVERSITY   (Australia)

Author keywords

Flavivirus; Importins; Nuclear transport inhibitors; Viral infection; Zika virus

Indexed keywords

FENRETINIDE; IVERMECTIN; KARYOPHERIN ALPHA; KARYOPHERIN BETA; NONSTRUCTURAL PROTEIN 5; ANTIVIRUS AGENT; NS5 PROTEIN, DENGUE VIRUS; VIRAL PROTEIN;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; EC50; IC50; NONHUMAN; PRIORITY JOURNAL; VERO CELL LINE; VIRUS CELL INTERACTION; ZIKA FEVER; ZIKA VIRUS; AMINO ACID SEQUENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHLOROCEBUS AETHIOPS; CONSERVED SEQUENCE; DRUG EFFECTS; GENETICS; HUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PHYSIOLOGY; VIROLOGY; VIRUS REPLICATION; ZIKA VIRUS INFECTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ALPHA KARYOPHERINS; AMINO ACID SEQUENCE; ANIMALS; ANTIVIRAL AGENTS; BETA KARYOPHERINS; CERCOPITHECUS AETHIOPS; CONSERVED SEQUENCE; FENRETINIDE; HUMANS; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85030750923     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2017.10.016     Document Type: Article

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