메뉴 건너뛰기




Volumn 8, Issue , 2017, Pages

Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase

Author keywords

[No Author keywords available]

Indexed keywords

RNA DIRECTED RNA POLYMERASE; ANTIVIRUS AGENT; NS5 PROTEIN, FLAVIVIRUS; VIRAL PROTEIN;

EID: 85016145551     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms14764     Document Type: Article
Times cited : (97)

References (24)
  • 1
    • 84961653991 scopus 로고    scopus 로고
    • Zika virus in the Americas: Early epidemiological and genetic findings
    • Faria, N. R., et al. Zika virus in the Americas: early epidemiological and genetic findings. Science 352, 345-349 (2016).
    • (2016) Science , vol.352 , pp. 345-349
    • Faria, N.R.1
  • 2
    • 85006484748 scopus 로고    scopus 로고
    • Fetal infection by Zika virus in the third trimester-report of 2 cases
    • Soares de Souza, A., et al. Fetal infection by Zika virus in the third trimester-report of 2 cases. Clin. Infect. Dis. 63, 1622-1625 (2016).
    • (2016) Clin. Infect. Dis. , vol.63 , pp. 1622-1625
    • Soares De Souza, A.1
  • 3
    • 84990033155 scopus 로고    scopus 로고
    • Zika virus in semen of a patient returning from a non-epidemic area
    • Mansuy, J. M., et al. Zika virus in semen of a patient returning from a non-epidemic area. Lancet Infect. Dis. 16, 894-895 (2016).
    • (2016) Lancet Infect. Dis. , vol.16 , pp. 894-895
    • Mansuy, J.M.1
  • 4
    • 84928889480 scopus 로고    scopus 로고
    • The dengue virus NS5 protein as a target for drug discovery
    • Lim, S. P., Noble, C. G., Shi, P.-Y. The dengue virus NS5 protein as a target for drug discovery. Antiviral Res. 119, 57-67 (2015).
    • (2015) Antiviral Res. , vol.119 , pp. 57-67
    • Lim, S.P.1    Noble, C.G.2    Shi, P.-Y.3
  • 5
    • 79952170633 scopus 로고    scopus 로고
    • Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase NS5B
    • Powdrill, M. H., Bernatchez, J. A., Götte, M. Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase NS5B. Viruses 2, 2169-2195 (2010).
    • (2010) Viruses , vol.2 , pp. 2169-2195
    • Powdrill, M.H.1    Bernatchez, J.A.2    Götte, M.3
  • 6
    • 84984824834 scopus 로고    scopus 로고
    • Potent allosteric dengue virus NS5 polymerase inhibitors: Mechanism of action and resistance profiling
    • Lim, S. P., et al. Potent allosteric dengue virus NS5 polymerase inhibitors: mechanism of action and resistance profiling. PLoS Pathog. 12, e1005737 (2016).
    • (2016) PLoS Pathog. , vol.12 , pp. e1005737
    • Lim, S.P.1
  • 7
    • 84966264850 scopus 로고    scopus 로고
    • Discovery of potent non-nucleoside inhibitors of dengue viral RNA-dependent RNA polymerase from a fragment hit using structure-based drug design
    • Yokokawa, F., et al. Discovery of potent non-nucleoside inhibitors of dengue viral RNA-dependent RNA polymerase from a fragment hit using structure-based drug design. J. Med. Chem. 59, 3935-3952 (2016).
    • (2016) J. Med. Chem. , vol.59 , pp. 3935-3952
    • Yokokawa, F.1
  • 8
    • 84976562760 scopus 로고    scopus 로고
    • Identification of dengue viral RNA-dependent RNA polymerase inhibitor using computational fragmentbased approaches and molecular dynamics study
    • Anusuya, S., Velmurugan, D., Gromiha, M. M. Identification of dengue viral RNA-dependent RNA polymerase inhibitor using computational fragmentbased approaches and molecular dynamics study. J. Biomol. Struct. Dyn. 34, 1512-1532 (2016).
    • (2016) J. Biomol. Struct. Dyn. , vol.34 , pp. 1512-1532
    • Anusuya, S.1    Velmurugan, D.2    Gromiha, M.M.3
  • 9
    • 84908177059 scopus 로고    scopus 로고
    • Regulation of Flavivirus RNA synthesis and replication
    • Selisko, B., Wang, C., Harris, E., Canard, B. Regulation of Flavivirus RNA synthesis and replication. Curr. Opin. Virol. 9, 74-83 (2014).
    • (2014) Curr. Opin. Virol. , vol.9 , pp. 74-83
    • Selisko, B.1    Wang, C.2    Harris, E.3    Canard, B.4
  • 10
    • 34249845069 scopus 로고    scopus 로고
    • Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
    • Malet, H., et al. Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5. J. Biol. Chem. 282, 10678-10689 (2007).
    • (2007) J. Biol. Chem. , vol.282 , pp. 10678-10689
    • Malet, H.1
  • 11
    • 84895824915 scopus 로고    scopus 로고
    • RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state
    • Surana, P., Satchidanandam, V., Nair, D. T. RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state. Nucleic Acids Res. 42, 2758-2773 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. 2758-2773
    • Surana, P.1    Satchidanandam, V.2    Nair, D.T.3
  • 12
    • 34247610261 scopus 로고    scopus 로고
    • Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1. 85-angstrom resolution
    • Yap, T. L., et al. Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1. 85-angstrom resolution. J. Virol. 81, 4753-4765 (2007).
    • (2007) J. Virol. , vol.81 , pp. 4753-4765
    • Yap, T.L.1
  • 13
    • 84988592621 scopus 로고    scopus 로고
    • Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor
    • Tarantino, D., et al. Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor. Antiviral Res. 134, 226-235 (2016).
    • (2016) Antiviral Res. , vol.134 , pp. 226-235
    • Tarantino, D.1
  • 14
    • 0025085655 scopus 로고
    • Ligation-independent cloning of PCR products (LIC-PCR)
    • Aslanidis, C., de Jong, P. J. Ligation-independent cloning of PCR products (LIC-PCR). Nucleic Acids Res. 18, 6069-6074 (1990).
    • (1990) Nucleic Acids Res. , vol.18 , pp. 6069-6074
    • Aslanidis, C.1    De Jong, P.J.2
  • 15
    • 0032619552 scopus 로고    scopus 로고
    • Protein identification and analysis tools in the ExPASy server
    • Wilkins, M. R., et al. Protein identification and analysis tools in the ExPASy server. Methods Mol. Biol. 112, 531-552 (1999).
    • (1999) Methods Mol. Biol. , vol.112 , pp. 531-552
    • Wilkins, M.R.1
  • 18
    • 34447508216 scopus 로고    scopus 로고
    • Phaser crystallographic software
    • McCoy, A. J., et al. Phaser crystallographic software. J. Appl. Crystallogr. 40, 658-674 (2007).
    • (2007) J. Appl. Crystallogr. , vol.40 , pp. 658-674
    • McCoy, A.J.1
  • 19
    • 37349103121 scopus 로고    scopus 로고
    • Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard
    • Terwilliger, T. C., et al. Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard. Acta Crystallogr. D Biol. Crystallogr. 64, 61-69 (2008).
    • (2008) Acta Crystallogr. D Biol. Crystallogr. , vol.64 , pp. 61-69
    • Terwilliger, T.C.1
  • 20
    • 76449098262 scopus 로고    scopus 로고
    • PHENIX: A comprehensive Python-based system for macromolecular structure solution
    • Adams, P. D., et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D Biol. Crystallogr. 66, 213-221 (2010).
    • (2010) Acta Crystallogr. D Biol. Crystallogr. , vol.66 , pp. 213-221
    • Adams, P.D.1
  • 21
    • 84860273177 scopus 로고    scopus 로고
    • Towards automated crystallographic structure refinement with phenix. Refine
    • Afonine, P. V., et al. Towards automated crystallographic structure refinement with phenix. refine. Acta Crystallogr. D Biol. Crystallogr. 68, 352-367 (2012).
    • (2012) Acta Crystallogr. D Biol. Crystallogr. , vol.68 , pp. 352-367
    • Afonine, P.V.1
  • 23
    • 74549178560 scopus 로고    scopus 로고
    • MolProbity: All-atom structure validation for macromolecular crystallography
    • Chen, V. B., et al. MolProbity: all-atom structure validation for macromolecular crystallography. Acta Crystallogr. D Biol. Crystallogr. 66, 12-21 (2010).
    • (2010) Acta Crystallogr. D Biol. Crystallogr. , vol.66 , pp. 12-21
    • Chen, V.B.1
  • 24
    • 84891668860 scopus 로고    scopus 로고
    • Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server
    • Zheng, H., et al. Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server. Nat. Protoc. 9, 156-170 (2014).
    • (2014) Nat. Protoc. , vol.9 , pp. 156-170
    • Zheng, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.