An AlphaScreen®-based assay for high-throughput screening for specific inhibitors of nuclear import

Journal of Biomolecular Screening

Volumn 16, Issue 2, 2011, Pages 192-200

  Wagstaff, Kylie M ^a   Rawlinson, Stephen M ^a   Hearps, Anna C ^b   Jans, David A ^a  

^a MONASH UNIVERSITY   (Australia)

^b BURNET INSTITUTE   (Australia)

Author keywords

AlphaScreen ; high throughput screen; HIV 1 integrase inhibitors; importins; protein interactions

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; GREEN FLUORESCENT PROTEIN; INTEGRASE; INTEGRASE INHIBITOR; IVERMECTIN; KARYOPHERIN ALPHA; KARYOPHERIN BETA; MIFEPRISTONE; NUCLEAR PROTEIN;

ARTICLE; BIOTINYLATION; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG SCREENING; DRUG SPECIFICITY; FEMALE; GENETIC TRANSFECTION; HELA CELL; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NUCLEAR IMPORT; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SCREENING TEST;

ACTIVE TRANSPORT, CELL NUCLEUS; ALPHA KARYOPHERINS; ANTIPARASITIC AGENTS; BETA KARYOPHERINS; CELL NUCLEUS; DRUG DISCOVERY; HELA CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HIV INTEGRASE; HORMONE ANTAGONISTS; HUMANS; IVERMECTIN; MIFEPRISTONE; PROTEIN BINDING; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 79951975187     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057110390360     Document Type: Article

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