Emergence and clonal spread of colistin resistance due to multiple mutational mechanisms in carbapenemase-producing Klebsiella pneumoniae in London

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Otter, Jonathan A ^a,b   Doumith, Michel ^c   Davies, Frances ^b   Mookerjee, Siddharth ^b   Dyakova, Eleonora ^b   Gilchrist, Mark ^b   Brannigan, Eimear T ^b   Bamford, Kathleen ^b   Galletly, Tracey ^b   Donaldson, Hugo ^b   Aanensen, David M ^d,e   Ellington, Matthew J ^a,c   Hill, Robert ^c   Turton, Jane F ^c   Hopkins, Katie L ^a,c   Woodford, Neil ^a,c   Holmes, Alison ^a,b  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b ST MARY S HOSPITAL   (United Kingdom)

^c PUBLIC HEALTH ENGLAND   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e Centre for Genomic Pathogen Surveillance (cGPS)   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BETA LACTAMASE; CARBAPENEMASE; COLISTIN;

AGED; ANTIBIOTIC RESISTANCE; BACTERIAL GENOME; CHEMISTRY; DRUG EFFECT; ENGLAND; EPIDEMIC; FEMALE; GENETICS; HUMAN; KLEBSIELLA INFECTION; KLEBSIELLA PNEUMONIAE; MALE; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MIDDLE AGED; MUTATION; PATHOGENICITY; VERY ELDERLY; WHOLE GENOME SEQUENCING;

AGED; AGED, 80 AND OVER; BACTERIAL PROTEINS; BETA-LACTAMASES; COLISTIN; DISEASE OUTBREAKS; DRUG RESISTANCE, BACTERIAL; FEMALE; GENOME, BACTERIAL; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LONDON; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MUTATION; WHOLE GENOME SEQUENCING;

EID: 85030668575     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-12637-4     Document Type: Article

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