메뉴 건너뛰기




Volumn 70, Issue 8, 2015, Pages 2261-2270

Unravelling of a mechanism of resistance to colistin in Klebsiella pneumoniae using atomic force microscopy

Author keywords

Atomic force microscopy; Capsules; Colistin resistance; Gene expression; K. pneumoniae

Indexed keywords

COLISTIN; LIPOPOLYSACCHARIDE; ANTIINFECTIVE AGENT;

EID: 84939529266     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkv118     Document Type: Article
Times cited : (51)

References (56)
  • 1
    • 34848848435 scopus 로고    scopus 로고
    • The changing face of Klebsiella pneumoniae infections in the community
    • Keynan Y, Rubinstein E. The changing face of Klebsiella pneumoniae infections in the community. Int J Antimicrob Agents 2007; 30: 385-9.
    • (2007) Int J Antimicrob Agents , vol.30 , pp. 385-389
    • Keynan, Y.1    Rubinstein, E.2
  • 2
    • 0031792165 scopus 로고    scopus 로고
    • Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors
    • Podschun R, Ullmann U. Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev 1998; 11: 589-603.
    • (1998) Clin Microbiol Rev , vol.11 , pp. 589-603
    • Podschun, R.1    Ullmann, U.2
  • 3
    • 0141928012 scopus 로고    scopus 로고
    • Extended spectrum b lactamase-producing Klebsiella pneumoniae infections: a review of the literature
    • Gupta A, Ampofo K, Rubenstein D et al. Extended spectrum b lactamase-producing Klebsiella pneumoniae infections: a review of the literature. J Perinatol 2003; 23: 439-43.
    • (2003) J Perinatol , vol.23 , pp. 439-443
    • Gupta, A.1    Ampofo, K.2    Rubenstein, D.3
  • 4
    • 84862868998 scopus 로고    scopus 로고
    • Current epidemiology and growing resistance of Gram-negative pathogens
    • Livermore DM. Current epidemiology and growing resistance of Gram-negative pathogens. Korean J Intern Med 2012; 27: 128-42.
    • (2012) Korean J Intern Med , vol.27 , pp. 128-142
    • Livermore, D.M.1
  • 5
    • 0026089266 scopus 로고
    • Properties of plasmids responsible for production of extended-spectrum β-lactamases
    • Jacoby GA, Sutton L. Properties of plasmids responsible for production of extended-spectrum β-lactamases. Antimicrob Agents Chemother 1991; 35: 164-9.
    • (1991) Antimicrob Agents Chemother , vol.35 , pp. 164-169
    • Jacoby, G.A.1    Sutton, L.2
  • 7
    • 0033836155 scopus 로고    scopus 로고
    • Characterization of the extendedspectrum β-lactamase reference strain, Klebsiella pneumoniae K6 (ATCC 700603), which produces the novel enzyme SHV-18
    • Rasheed JK, Anderson GJ, Yigit H et al. Characterization of the extendedspectrum β-lactamase reference strain, Klebsiella pneumoniae K6 (ATCC 700603), which produces the novel enzyme SHV-18. Antimicrob Agents Chemother 2000; 44: 2382-8.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2382-2388
    • Rasheed, J.K.1    Anderson, G.J.2    Yigit, H.3
  • 8
    • 82455185152 scopus 로고    scopus 로고
    • Sensitive and specific modified Hodge test for KPC and metallo-β-lactamase detection in Pseudomonas aeruginosa by use of a novel indicator strain, Klebsiella pneumoniae ATCC 700603
    • Pasteran F, Veliz O, Rapoport M et al. Sensitive and specific modified Hodge test for KPC and metallo-β-lactamase detection in Pseudomonas aeruginosa by use of a novel indicator strain, Klebsiella pneumoniae ATCC 700603. J Clin Microbiol 2011; 49: 4301-3.
    • (2011) J Clin Microbiol , vol.49 , pp. 4301-4303
    • Pasteran, F.1    Veliz, O.2    Rapoport, M.3
  • 9
    • 77149165713 scopus 로고    scopus 로고
    • Updated functional classification of β-lactamases
    • Bush K, Jacoby GA. Updated functional classification of β-lactamases. Antimicrob Agents Chemother 2010; 54: 969-76.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 969-976
    • Bush, K.1    Jacoby, G.A.2
  • 10
    • 84882712084 scopus 로고    scopus 로고
    • Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases
    • Munoz-Price LS, Poirel L, Bonomo RA et al. Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases. Lancet Infect Dis 2013; 13: 785-96.
    • (2013) Lancet Infect Dis , vol.13 , pp. 785-796
    • Munoz-Price, L.S.1    Poirel, L.2    Bonomo, R.A.3
  • 12
    • 84880681078 scopus 로고    scopus 로고
    • Novel derivatives of polymyxins
    • Vaara M. Novel derivatives of polymyxins. J Antimicrob Chemother 2013; 68: 1213-9.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 1213-1219
    • Vaara, M.1
  • 13
    • 0014801502 scopus 로고
    • Adverse effects of sodium colistimethate. Manifestations and specific reaction rates during 317 courses of therapy
    • Koch-Weser J, Sidel VW, Federman EB et al. Adverse effects of sodium colistimethate. Manifestations and specific reaction rates during 317 courses of therapy. Ann Intern Med 1970; 72: 857-68.
    • (1970) Ann Intern Med , vol.72 , pp. 857-868
    • Koch-Weser, J.1    Sidel, V.W.2    Federman, E.B.3
  • 14
    • 70350528719 scopus 로고    scopus 로고
    • Colistin in the 21st century
    • Nation RL, Li J. Colistin in the 21st century. Curr Opin Infect Dis 2009; 22: 535-43.
    • (2009) Curr Opin Infect Dis , vol.22 , pp. 535-543
    • Nation, R.L.1    Li, J.2
  • 16
    • 77949346087 scopus 로고    scopus 로고
    • Structure-activity relationships of polymyxin antibiotics
    • Velkov T, Thompson PE, Nation RL et al. Structure-activity relationships of polymyxin antibiotics. J Med Chem 2010; 53: 1898-916.
    • (2010) J Med Chem , vol.53 , pp. 1898-1916
    • Velkov, T.1    Thompson, P.E.2    Nation, R.L.3
  • 17
    • 0034424412 scopus 로고    scopus 로고
    • Interactions of bacterial cationic peptide antibiotics with outer and cytoplasmic membranes of Pseudomonas aeruginosa
    • Zhang L, Dhillon P, Yan H et al. Interactions of bacterial cationic peptide antibiotics with outer and cytoplasmic membranes of Pseudomonas aeruginosa. Antimicrob Agents Chemother 2000; 44: 3317-21.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 3317-3321
    • Zhang, L.1    Dhillon, P.2    Yan, H.3
  • 18
    • 84878293341 scopus 로고    scopus 로고
    • Pharmacology of polymyxins: new insights into an 'old' class of antibiotics
    • Velkov T, Roberts KD, Nation RL et al. Pharmacology of polymyxins: new insights into an 'old' class of antibiotics. Future Microbiol 2013; 8: 711-24.
    • (2013) Future Microbiol , vol.8 , pp. 711-724
    • Velkov, T.1    Roberts, K.D.2    Nation, R.L.3
  • 19
    • 84987804431 scopus 로고    scopus 로고
    • Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria
    • Olaitan AO, Morand S, Rolain J-M. Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria. Antimicrob Resist Chemother 2014; 5: 643.
    • (2014) Antimicrob Resist Chemother , vol.5 , pp. 643
    • Olaitan, A.O.1    Morand, S.2    Rolain, J.-M.3
  • 21
    • 77957951965 scopus 로고    scopus 로고
    • Resistance to polymyxins: mechanisms, frequency and treatment options
    • Falagas ME, Rafailidis PI, Matthaiou DK. Resistance to polymyxins: mechanisms, frequency and treatment options. Drug Resist Updat 2010; 13: 132-8.
    • (2010) Drug Resist Updat , vol.13 , pp. 132-138
    • Falagas, M.E.1    Rafailidis, P.I.2    Matthaiou, D.K.3
  • 22
    • 0347479229 scopus 로고    scopus 로고
    • Molecular basis of bacterial outer membrane permeability revisited
    • Nikaido H. Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biol Rev 2003; 67: 593-656.
    • (2003) Microbiol Mol Biol Rev , vol.67 , pp. 593-656
    • Nikaido, H.1
  • 23
    • 84885909781 scopus 로고    scopus 로고
    • In vivo emergence of colistin resistance in Klebsiella pneumoniae producing KPC-type carbapenemases mediated by insertional inactivation of the PhoQ/PhoP mgrB regulator
    • Cannatelli A, D'Andrea MM, Giani T et al. In vivo emergence of colistin resistance in Klebsiella pneumoniae producing KPC-type carbapenemases mediated by insertional inactivation of the PhoQ/PhoP mgrB regulator. Antimicrob Agents Chemother 2013; 57: 5521-6.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 5521-5526
    • Cannatelli, A.1    D'Andrea, M.M.2    Giani, T.3
  • 24
    • 84926489004 scopus 로고    scopus 로고
    • The mgrB gene as a key target for acquired resistance to colistin in Klebsiella pneumoniae
    • Poirel L, Jayol A, Bontron S et al. The mgrB gene as a key target for acquired resistance to colistin in Klebsiella pneumoniae. J Antimicrob Chemother 2015; 70: 75-80.
    • (2015) J Antimicrob Chemother , vol.70 , pp. 75-80
    • Poirel, L.1    Jayol, A.2    Bontron, S.3
  • 26
    • 79960924956 scopus 로고    scopus 로고
    • Atomic force microscopy: a nanoscopic window on the cell surface
    • Müller DJ, Dufrêne YF. Atomic force microscopy: a nanoscopic window on the cell surface. Trends Cell Biol 2011; 21: 461-9.
    • (2011) Trends Cell Biol , vol.21 , pp. 461-469
    • Müller, D.J.1    Dufrêne, Y.F.2
  • 27
    • 84855334394 scopus 로고    scopus 로고
    • Nanoscale effects of antibiotics on P. aeruginosa
    • Formosa C, Grare M, Duval RE et al. Nanoscale effects of antibiotics on P. aeruginosa. Nanomedicine 2012; 8: 12-6.
    • (2012) Nanomedicine , vol.8 , pp. 12-16
    • Formosa, C.1    Grare, M.2    Duval, R.E.3
  • 28
    • 84866059120 scopus 로고    scopus 로고
    • Nanoscale analysis of the effects of antibiotics and CX1 on a Pseudomonas aeruginosa multidrug-resistant strain
    • Formosa C, Grare M, Jauvert E et al. Nanoscale analysis of the effects of antibiotics and CX1 on a Pseudomonas aeruginosa multidrug-resistant strain. Sci Rep 2012; 2: 575.
    • (2012) Sci Rep , vol.2 , pp. 575
    • Formosa, C.1    Grare, M.2    Jauvert, E.3
  • 29
    • 84880314273 scopus 로고    scopus 로고
    • Nanoscale effects of caspofungin against two yeast species, Saccharomyces cerevisiae and Candida albicans
    • Formosa C, Schiavone M, Martin-Yken H et al. Nanoscale effects of caspofungin against two yeast species, Saccharomyces cerevisiae and Candida albicans. Antimicrob Agents Chemother 2013; 57: 3498-506.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 3498-3506
    • Formosa, C.1    Schiavone, M.2    Martin-Yken, H.3
  • 30
    • 84872702002 scopus 로고    scopus 로고
    • Nanoscale analysis of caspofungin-induced cell surface remodelling in Candida albicans
    • El-Kirat-Chatel S, Beaussart A, Alsteens D et al. Nanoscale analysis of caspofungin-induced cell surface remodelling in Candida albicans. Nanoscale 2013; 5: 1105-15.
    • (2013) Nanoscale , vol.5 , pp. 1105-1115
    • El-Kirat-Chatel, S.1    Beaussart, A.2    Alsteens, D.3
  • 31
    • 80255123890 scopus 로고    scopus 로고
    • Effect of colistin exposure and growth phase on the surface properties of live Acinetobacter baumannii cells examined by atomic force microscopy
    • Soon RL, Nation RL, Harper M et al. Effect of colistin exposure and growth phase on the surface properties of live Acinetobacter baumannii cells examined by atomic force microscopy. Int J Antimicrob Agents 2011; 38: 493-501.
    • (2011) Int J Antimicrob Agents , vol.38 , pp. 493-501
    • Soon, R.L.1    Nation, R.L.2    Harper, M.3
  • 32
    • 71249141054 scopus 로고    scopus 로고
    • Atomic force microscopy investigation of the morphology and topography of colistin-heteroresistant Acinetobacter baumannii strains as a function of growth phase and in response to colistin treatment
    • Soon RL, Nation RL, Hartley PG et al. Atomic force microscopy investigation of the morphology and topography of colistin-heteroresistant Acinetobacter baumannii strains as a function of growth phase and in response to colistin treatment. Antimicrob Agents Chemother 2009; 53: 4979-86.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 4979-4986
    • Soon, R.L.1    Nation, R.L.2    Hartley, P.G.3
  • 33
    • 65449120367 scopus 로고    scopus 로고
    • Effects of colistin on surface ultrastructure and nanomechanics of Pseudomonas aeruginosa cells
    • Mortensen NP, Fowlkes JD, Sullivan CJ et al. Effects of colistin on surface ultrastructure and nanomechanics of Pseudomonas aeruginosa cells. Langmuir 2009; 25: 3728-33.
    • (2009) Langmuir , vol.25 , pp. 3728-3733
    • Mortensen, N.P.1    Fowlkes, J.D.2    Sullivan, C.J.3
  • 35
    • 41849091845 scopus 로고    scopus 로고
    • Nanostructure and nanomechanics of live Phaeodactylum tricornutum morphotypes
    • Francius G, Tesson B, Dague E et al. Nanostructure and nanomechanics of live Phaeodactylum tricornutum morphotypes. Environ Microbiol 2008; 10: 1344-56.
    • (2008) Environ Microbiol , vol.10 , pp. 1344-1356
    • Francius, G.1    Tesson, B.2    Dague, E.3
  • 36
    • 36449007442 scopus 로고
    • Calibration of atomic-force microscope tips
    • Hutter JL, Bechhoefer J. Calibration of atomic-force microscope tips. Rev Sci Instrum 1993; 64: 1868-73.
    • (1993) Rev Sci Instrum , vol.64 , pp. 1868-1873
    • Hutter, J.L.1    Bechhoefer, J.2
  • 37
    • 84934701192 scopus 로고
    • Ueber die Beruhrung fester elastischer Korper
    • Hertz H. Ueber die Beruhrung fester elastischer Korper. J Reine Angew Math 1881; 92: 156-71.
    • (1881) J Reine Angew Math , vol.92 , pp. 156-171
    • Hertz, H.1
  • 38
    • 0034214948 scopus 로고    scopus 로고
    • Bacterial turgor pressure can be measured by atomic force microscopy
    • Arnoldi M, Fritz M, Bäuerlein E et al. Bacterial turgor pressure can be measured by atomic force microscopy. Phys Rev E 2000; 62: 1034-44.
    • (2000) Phys Rev E , vol.62 , pp. 1034-1044
    • Arnoldi, M.1    Fritz, M.2    Bäuerlein, E.3
  • 39
    • 84875957066 scopus 로고    scopus 로고
    • Imaging living cells surface and quantifying its properties at high resolution using AFM in QITM mode
    • Chopinet L, Formosa C, Rols MP et al. Imaging living cells surface and quantifying its properties at high resolution using AFM in QITM mode. Micron 2013; 48: 26-33.
    • (2013) Micron , vol.48 , pp. 26-33
    • Chopinet, L.1    Formosa, C.2    Rols, M.P.3
  • 40
    • 84902248183 scopus 로고    scopus 로고
    • Differential expression of two-component systems, pmrAB and phoPQ, with different growth phases of Klebsiella pneumoniae in the presence or absence of colistin
    • Kim SY, Choi HJ, Ko KS. Differential expression of two-component systems, pmrAB and phoPQ, with different growth phases of Klebsiella pneumoniae in the presence or absence of colistin. Curr Microbiol 2014; 69: 37-41.
    • (2014) Curr Microbiol , vol.69 , pp. 37-41
    • Kim, S.Y.1    Choi, H.J.2    Ko, K.S.3
  • 41
    • 84911918980 scopus 로고    scopus 로고
    • Worldwide emergence of colistin resistance in Klebsiella pneumoniae from healthy humans and patients in Lao PDR, Thailand, Israel, Nigeria and France owing to inactivation of the PhoP/PhoQ regulator mgrB: an epidemiological and molecular study
    • Olaitan AO, Diene SM, Kempf M et al. Worldwide emergence of colistin resistance in Klebsiella pneumoniae from healthy humans and patients in Lao PDR, Thailand, Israel, Nigeria and France owing to inactivation of the PhoP/PhoQ regulator mgrB: an epidemiological and molecular study. Int J Antimicrob Agents 2014; 44: 500-7.
    • (2014) Int J Antimicrob Agents , vol.44 , pp. 500-507
    • Olaitan, A.O.1    Diene, S.M.2    Kempf, M.3
  • 42
    • 84905394181 scopus 로고    scopus 로고
    • In vivo evolution to colistin resistance by PmrB sensor kinase mutation in KPC-producing Klebsiella pneumoniae is associated with low-dosage colistin treatment
    • Cannatelli A, Pilato VD, Giani T et al. In vivo evolution to colistin resistance by PmrB sensor kinase mutation in KPC-producing Klebsiella pneumoniae is associated with low-dosage colistin treatment. Antimicrob Agents Chemother 2014; 58: 4399-403.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 4399-4403
    • Cannatelli, A.1    Pilato, V.D.2    Giani, T.3
  • 43
    • 84905399119 scopus 로고    scopus 로고
    • Resistance to colistin associated with a single amino acid change in protein PmrB among Klebsiella pneumoniae isolates of worldwide origin
    • Jayol A, Poirel L, Brink A et al. Resistance to colistin associated with a single amino acid change in protein PmrB among Klebsiella pneumoniae isolates of worldwide origin. Antimicrob Agents Chemother 2014; 58: 4762-6.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 4762-4766
    • Jayol, A.1    Poirel, L.2    Brink, A.3
  • 44
    • 34548605458 scopus 로고    scopus 로고
    • Lipid A modification systems in Gram-negative bacteria
    • Raetz CRH, Reynolds CM, Trent MS et al. Lipid A modification systems in Gram-negative bacteria. Annu Rev Biochem 2007; 76: 295-329.
    • (2007) Annu Rev Biochem , vol.76 , pp. 295-329
    • Raetz, C.R.H.1    Reynolds, C.M.2    Trent, M.S.3
  • 45
    • 74249107490 scopus 로고    scopus 로고
    • Feedback inhibition in the PhoQ/PhoP signaling system by a membrane peptide
    • Lippa AM, Goulian M. Feedback inhibition in the PhoQ/PhoP signaling system by a membrane peptide. PLoS Genet 2009; 5: e1000788.
    • (2009) PLoS Genet , vol.5
    • Lippa, A.M.1    Goulian, M.2
  • 46
    • 84939542979 scopus 로고    scopus 로고
    • Effects of the strain background and autolysis process on the composition and biophysical properties of the cell wall from two different industrial yeasts
    • Schiavone M, Sieczkowski N, Castex M et al. Effects of the strain background and autolysis process on the composition and biophysical properties of the cell wall from two different industrial yeasts. FEMS Yeast Res 2015; 15: 1-11.
    • (2015) FEMS Yeast Res , vol.15 , pp. 1-11
    • Schiavone, M.1    Sieczkowski, N.2    Castex, M.3
  • 47
    • 84867655439 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of 'old' polymyxins: what is new?
    • Bergen PJ, Landersdorfer CB, Zhang J et al. Pharmacokinetics and pharmacodynamics of 'old' polymyxins: what is new? Diagn Microbiol Infect Dis 2012; 74: 213-23.
    • (2012) Diagn Microbiol Infect Dis , vol.74 , pp. 213-223
    • Bergen, P.J.1    Landersdorfer, C.B.2    Zhang, J.3
  • 48
    • 70849102756 scopus 로고    scopus 로고
    • Gramicidin S and polymyxins: the revival of cationic cyclic peptide antibiotics
    • Mogi T, Kita K. Gramicidin S and polymyxins: the revival of cationic cyclic peptide antibiotics. Cell Mol Life Sci 2009; 66: 3821-6.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 3821-3826
    • Mogi, T.1    Kita, K.2
  • 49
    • 37349104237 scopus 로고    scopus 로고
    • Alternative mechanisms of action of cationic antimicrobial peptides on bacteria
    • Hale JD, Hancock RE. Alternative mechanisms of action of cationic antimicrobial peptides on bacteria. Expert Rev Anti Infect Ther 2007; 5: 951-9.
    • (2007) Expert Rev Anti Infect Ther , vol.5 , pp. 951-959
    • Hale, J.D.1    Hancock, R.E.2
  • 50
    • 0021999551 scopus 로고
    • Antibacterial action of colistin (polymyxin E) against Mycobacterium aurum
    • David HL, Rastogi N. Antibacterial action of colistin (polymyxin E) against Mycobacterium aurum. Antimicrob Agents Chemother 1985; 27: 701-7.
    • (1985) Antimicrob Agents Chemother , vol.27 , pp. 701-707
    • David, H.L.1    Rastogi, N.2
  • 51
    • 14544282377 scopus 로고    scopus 로고
    • Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?
    • Brogden KA. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol 2005; 3: 238-50.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 238-250
    • Brogden, K.A.1
  • 52
    • 9244224674 scopus 로고    scopus 로고
    • Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides
    • Campos MA, Vargas MA, Regueiro V et al. Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides. Infect Immun 2004; 72: 7107-14.
    • (2004) Infect Immun , vol.72 , pp. 7107-7114
    • Campos, M.A.1    Vargas, M.A.2    Regueiro, V.3
  • 53
    • 58949097012 scopus 로고    scopus 로고
    • Capsule polysaccharide is a bacterial decoy for antimicrobial peptides
    • Llobet E, Tomás JM, Bengoechea JA. Capsule polysaccharide is a bacterial decoy for antimicrobial peptides. Microbiology 2008; 154: 3877-86.
    • (2008) Microbiology , vol.154 , pp. 3877-3886
    • Llobet, E.1    Tomás, J.M.2    Bengoechea, J.A.3
  • 54
    • 84899452876 scopus 로고    scopus 로고
    • In situ mechanical characterization of the cell nucleus by atomic force microscopy
    • Liu H, Wen J, Xiao Y et al. In situ mechanical characterization of the cell nucleus by atomic force microscopy. ACS Nano 2014; 8: 3821-8.
    • (2014) ACS Nano , vol.8 , pp. 3821-3828
    • Liu, H.1    Wen, J.2    Xiao, Y.3
  • 55
    • 12844253726 scopus 로고    scopus 로고
    • Nanoscale operation of a living cell using an atomic force microscope with a nanoneedle
    • Obataya I, Nakamura C, Han S et al. Nanoscale operation of a living cell using an atomic force microscope with a nanoneedle. Nano Lett 2005; 5: 27-30.
    • (2005) Nano Lett , vol.5 , pp. 27-30
    • Obataya, I.1    Nakamura, C.2    Han, S.3
  • 56
    • 65249143305 scopus 로고    scopus 로고
    • Bacteria survive multiple puncturings of their cell walls
    • Suo Z, Avci R, Deliorman M et al. Bacteria survive multiple puncturings of their cell walls. Langmuir ACS J Surf Colloids 2009; 25: 4588-94.
    • (2009) Langmuir ACS J Surf Colloids , vol.25 , pp. 4588-4594
    • Suo, Z.1    Avci, R.2    Deliorman, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.