A genome-wide CRISPR screen reconciles the role of N-linked glycosylation in galectin-3 transport to the cell surface

Journal of Cell Science

Volumn 130, Issue 19, 2017, Pages 3234-3247

  Stewart, Sarah E ^a   Menzies, Sam A ^b   Popa, Stephanie J ^a   Savinykh, Natalia ^a   Harrison, Anna Petrunkina ^a   Lehner, Paul J ^b   Moreau, Kevin ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Galectin; Glycosylation; Unconventional secretion

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; ADAM10 ENDOPEPTIDASE; APLP2 PROTEIN; ARTN PROTEIN; C2 PROTEIN; CD302 PROTEIN; CD33 ANTIGEN; CHRM4 PROTEIN; CLCA1 PROTEIN; CTNND2 PROTEIN; DSG3 PROTEIN; FAP PROTEIN; FGF17 PROTEIN; FRAS1 PROTEIN; GALECTIN 3; GIF PROTEIN; GLYCOPROTEIN; HIST1H2BD PROTEIN; HS6ST2 PROTEIN; INTERLEUKIN 27; ITGB3 PROTEIN; LAMB2 PROTEIN; LUM PROTEIN; MAN1A2 PROTEIN; MPZL3 PROTEIN; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 3; NDST2 PROTEIN; NHLRC3 PROTEIN; NPR1 PROTEIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; GALECTIN-3, HUMAN;

ARTICLE; BINDING AFFINITY; CELL SURFACE; CONTROLLED STUDY; CRISPR-CAS9 SYSTEM; CYTOSOL; EXOSOME; EXTRACELLULAR SPACE; GLYCOSYLATION; HUMAN; HUMAN CELL; N LINKED GLYCOSYLATION; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN TRANSPORT; CRISPR CAS SYSTEM; ENDOPLASMIC RETICULUM; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GOLGI COMPLEX; HELA CELL LINE; METABOLISM; PHYSIOLOGY;

CRISPR-CAS SYSTEMS; ENDOPLASMIC RETICULUM; GALECTIN 3; GENOME-WIDE ASSOCIATION STUDY; GLYCOSYLATION; GOLGI APPARATUS; HELA CELLS; HUMANS; PROTEIN TRANSPORT;

EID: 85030530681     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.206425     Document Type: Article

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