Galectin-3 in patients with chronic heart failure: Association with oxidative stress, inflammation, renal dysfunction and prognosis

Minerva Cardioangiologica

Volumn 64, Issue 6, 2016, Pages 595-602

  Medvedeva, Elena A ^a   Berezin, Ivan I ^a   Surkova, Elena A ^a,b   Yaranov, Dmitry M ^c   Shchukin, Yuri V ^a  

^a SAMARA STATE MEDICAL UNIVERSITY   (Russian Federation)

^b UNIVERSITY OF PADOVA   (Italy)

^c DANBURY HOSPITAL   (United States)

Author keywords

Cystatin C; Galectin 3; Heart failure; Inflammation

Indexed keywords

3 NITROTYROSINE; BRAIN NATRIURETIC PEPTIDE; C REACTIVE PROTEIN; CYSTATIN C; EXTRACELLULAR SUPEROXIDE DISMUTASE; GALECTIN 3; INTERLEUKIN 6; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; BIOLOGICAL MARKER; CYTOKINE; GALECTIN-3, HUMAN;

ADULT; COHORT ANALYSIS; CONFERENCE PAPER; ECHOCARDIOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HEART FAILURE; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; INFLAMMATION; KIDNEY DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OXIDATIVE STRESS; PROGNOSIS; PROSPECTIVE STUDY; AGED; BLOOD; COMPLICATION; KIDNEY DISEASE;

AGED; BIOMARKERS; COHORT STUDIES; CYTOKINES; FEMALE; GALECTIN 3; HEART FAILURE; HUMANS; INFLAMMATION; KIDNEY DISEASES; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; OXIDATIVE STRESS; PROGNOSIS; PROSPECTIVE STUDIES;

EID: 84992154214     PISSN: 00264725     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (25)

1. Morrow DA, O'Donoghue ML. Galectin-3 in cardiovascular disease. Apossible window into early myocardial fibrosis. J Am Coll Cardiol 2012;60:1257-8.
2. Sharma UC, Pokharel S, van Brakel TJ, van Berlo JH, Cleutjens JP, Schroen B, et al. Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation 2004;110:3121-8.
3. Ueland T, Aukrust P, Broch K, Aakhus S, Skårdal R, Muntendam P, et al. Galectin-3 in heart failure: high levels are associated with all-cause mortality. Int J Cardiol 2011;150:361-4.
4. Lok DJ, Van Der Meer P, de la Porte PW, Lipsic E, Van Wijngaarden J, Hilledge HL, et al. Prognostic value of galectin-3, a novel marker of fibrosis, in patients with chronic heart failure: data from the DEAL-HF study. Clin Res Cardiol 2010;99:323-8.
5. de Boer RA, Lok DJ, Jaarsma T, Van Der Meer P, Voors AA, Hilledge HL, et al. Predictive value of plasma galectin-3 levels in heart failure with reduced and preserved ejection fraction. Ann Med 2011;43:60-8.
6. Felker GM, Fiuzat M, Shaw LK, Clare R, Whellan DJ, Bettari L, et al. Galectin-3 in ambulatory patients with heart failure: results from the HF-ACTION study. Circ Heart Fail 2012;5:72-8.
7. Gruson D, Ko G. Galectins testing: New promises for the diagnosis and risk stratification of chronic diseases? Clin Biochem 2012;45:719-26.
8. Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Drazner MH, et al. 2013 ACCF/AHAHeart Failure Guideline. Circulation 2013;128:e240-327.
9. Ragino Ju I, Voevoda MI, Dushkin MI. Application of new biochemical methods for an estimation of oxidative-antioxidative potential of low density lipoproteins. Clinical and laboratory diagnostics 2005;4:11-5 [Article in Russian].
10. Lu Z, Xu X, Hu X. Extracellular superoxide dismutase deficiency exacerbates pressure overload-induced left ventricular hypertrophy and dysfunction. Hypertension 2008;51:19-25.
11. Smilde TD, Van Veldhuisen DJ, Navis G, Voors AA, Hillege HL. Drawbacks and prognostic value of formulas estimating renal function in patients with chronic heart failure and systolic dysfunction. Circulation 2006;114:1572-80.
12. Henderson NC, Mackinnon AC, Farnworth SL, Kipari T, Haslett C, Iredale JP, et al. Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis. Am J Pathol 2008;172:288-98.
13. Paclik D, Werner L, Guckelberger O, Wiedenmann B, Sturm A. Galectins distinctively regulate central monocyte and macrophage function. Cell Immunol 2011;271:97-103.
14. Sharma UC, Pokharel S, van Brakel TJ, van Berlo JH, Cleutjes JP, Schroen B, et al. Galectin-3 marks activated macrophages in in failure-prone hypertrophiedhearts and contributes to cardiac dysfunction. Circulation 2004;110:3121-28.
15. Gopal DM, Kommineni M, Ayalon N, Koelbl C, Ayalon R, Biolo A, et al. Relationship of plasma galectin-3 to renal failure in patients with heart failure: effects of clinical status, pathophysiology of heart failure and presence or absence of heart failure. J Am Heart Assoc 2012 1:e000760.
16. Zhu W, Sano H, Nagai R, Fukuhara K, Miyazaki A, Horiuchi S. The role of galectin-3 in endocytosis of advanced glycation end products and modified low density lipoproteins. Biochem Biophys Res Commun 2001;2:1183-8.
17. de Filippi CR, Felker GM. Galectin-3 in heart failure-linking fibrosis, remodeling, and progression. US Cardiology 2010;7:67-70.
18. Liu YH, D'Ambrosio M, Liao TD, Peng H, Rhaleb NE, Sharma U, et al. N-acetyl-seryl-aspartyl-lysyl-proline prevents cardiac remodeling and dysfunction induced by galectin-3, a mammalian adhesion/growth-regulatory lectin. Am J Physiol Heart Circ Physiol 2009;296:404-12.
19. Boer RA, Yu L, Veldhuisen DJ. Galectin-3 in cardiac remodeling and heart failure. Curr Heart Fail Rep 2010;7:1-8.
20. Toprak G, Yüksel H, Demirpençe O, Islamoglu Y, Evliyaoglu O, Mete N Fibrosis in heart failure subtypes. Eur Rev Med Pharmacol Sci 2013;17:2302-9.
21. Suzuki Y, Inoue T, Yoshimaru T, Ra C. Galectin-3 but not galectin-1 induces mast cell death by oxidative stress and mitochondrial permeability transition. Biochim Biophys Acta 2008;1783:924-34.
22. Molnár A, Tóth A, Bagi Z, Papp Z, Edes I, Vaszily M, et al. Activation of the poly(ADP-Ribose) polymerase pathway in human heart failure. Mol Med 2006;12:143-52.
23. Lu Z, Xu X, Hu X. Extracellular superoxide dismutase deficiency exacerbates pressure overload-induced left ventricular hypertrophy and dysfunction. Hypertension 2008;51:19-25.
24. Leone M, Iacoviello M. The predictive value of plasma biomarkers in discharged heart failure patients: role of galectin-3. Minerva Cardioangiol 2016;64:181-94.
25. Calvier L, Miana M, Reboul P, Cachofeiro V, Martinez-Martinez E, de Boer RA, et al. Galectin-3 Mediates Aldosterone-Induced Vascular Fibrosis. Arterioscler Thromb Vasc Biol 2013;33:67-75.