Beyond RAS and BRAF: A target rich disease that is ripe for picking

Journal of Gastrointestinal Oncology

Volumn 7, Issue 5, 2016, Pages 705-712

  Friedrich, Tyler ^a   Leong, Stephen ^a   Lieu, Christopher H ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Colonic neoplasms; Mitogen activated protein kinases (MAPKs); Molecular targeted therapy; Protooncogene proteins B raf

Indexed keywords

B RAF KINASE; B RAF KINASE INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; K RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN KINASE B;

ADVANCED CANCER; CANCER IMMUNOTHERAPY; CANCER PROGNOSIS; COLORECTAL CANCER; DRUG TARGETING; GENE MUTATION; HUMAN; MOLECULARLY TARGETED THERAPY; MUTATIONAL ANALYSIS; NEXT GENERATION SEQUENCING; NONHUMAN; ONCOGENE; ONCOGENE BRAF; ONCOGENE RAS; PREDICTIVE VALUE; REVIEW; SIGNAL TRANSDUCTION;

EID: 85030225597     PISSN: 20786891     EISSN: 2219679X     Source Type: Journal    
DOI: 10.21037/jgo.2016.06.11     Document Type: Review

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