메뉴 건너뛰기




Volumn 16, Issue 3, 2018, Pages 727-736

A synthetic biology approach for consistent production of plant-made recombinant polyclonal antibodies against snake venom toxins

Author keywords

molecular pharming; recombinant polyclonal antibodies; snake antivenoms

Indexed keywords

PLANTIBODY; SNAKE VENOM; VENOM ANTISERUM;

EID: 85030123782     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/pbi.12823     Document Type: Article
Times cited : (31)

References (41)
  • 1
    • 84964478820 scopus 로고    scopus 로고
    • Synthetic biology tackles global antivenom shortage
    • Arnold, C. (2016) Synthetic biology tackles global antivenom shortage. Nature, 532, 292.
    • (2016) Nature , vol.532 , pp. 292
    • Arnold, C.1
  • 2
    • 77957338351 scopus 로고    scopus 로고
    • Mining human antibody repertoires
    • Beerli, R.R. and Rader, C. (2010) Mining human antibody repertoires. MAbs, 2, 365–378.
    • (2010) MAbs , vol.2 , pp. 365-378
    • Beerli, R.R.1    Rader, C.2
  • 3
    • 77950383145 scopus 로고    scopus 로고
    • Rapid, high-yield production in plants of individualized idiotype vaccines for non-Hodgkin's lymphoma
    • Bendandi, M., Marillonnet, S., Kandzia, R., Thieme, F., Nickstadt, A., Herz, S., Frode, R. et al. (2010) Rapid, high-yield production in plants of individualized idiotype vaccines for non-Hodgkin's lymphoma. Ann. Oncol. 21, 2420–2427.
    • (2010) Ann. Oncol. , vol.21 , pp. 2420-2427
    • Bendandi, M.1    Marillonnet, S.2    Kandzia, R.3    Thieme, F.4    Nickstadt, A.5    Herz, S.6    Frode, R.7
  • 4
    • 0015341766 scopus 로고
    • Toxicity of Costa Rican snake venoms for the white mouse
    • Bolanos, R. (1972) Toxicity of Costa Rican snake venoms for the white mouse. Am. J. Trop. Med. Hyg. 21, 360–363.
    • (1972) Am. J. Trop. Med. Hyg. , vol.21 , pp. 360-363
    • Bolanos, R.1
  • 5
    • 0032428679 scopus 로고    scopus 로고
    • Snake-bites: appraisal of the global situation
    • Chippaux, J.P. (1998) Snake-bites: appraisal of the global situation. Bull. World Health Organ. 76, 515–524.
    • (1998) Bull. World Health Organ. , vol.76 , pp. 515-524
    • Chippaux, J.P.1
  • 8
    • 0024372242 scopus 로고
    • Comparative study on coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom
    • Gene, J.A., Roy, A., Rojas, G., Gutierrez, J.M. and Cerdas, L. (1989) Comparative study on coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom. Toxicon, 27, 841–848.
    • (1989) Toxicon , vol.27 , pp. 841-848
    • Gene, J.A.1    Roy, A.2    Rojas, G.3    Gutierrez, J.M.4    Cerdas, L.5
  • 9
    • 84928571820 scopus 로고    scopus 로고
    • History of passive antibody administration for prevention and treatment of infectious diseases
    • Graham, B.S. and Ambrosino, D.M. (2015) History of passive antibody administration for prevention and treatment of infectious diseases. Current Opin. HIV AIDS, 10, 129–134.
    • (2015) Current Opin. HIV AIDS , vol.10 , pp. 129-134
    • Graham, B.S.1    Ambrosino, D.M.2
  • 10
    • 84927764135 scopus 로고    scopus 로고
    • Current challenges for confronting the public health problem of snakebite envenoming in Central America
    • Gutierrez, J.M. (2014a) Current challenges for confronting the public health problem of snakebite envenoming in Central America. J. Venom Anim. Toxins Incl. Trop. Dis. 20, 7.
    • (2014) J. Venom Anim. Toxins Incl. Trop. Dis. , vol.20 , pp. 7
    • Gutierrez, J.M.1
  • 11
    • 84906055495 scopus 로고    scopus 로고
    • Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead
    • Gutierrez, J.M. (2014b) Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead. Trans. R. Soc. Trop. Med. Hyg. 108, 530–537.
    • (2014) Trans. R. Soc. Trop. Med. Hyg. , vol.108 , pp. 530-537
    • Gutierrez, J.M.1
  • 12
    • 0022354215 scopus 로고
    • Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom
    • Gutierrez, J.M., Gene, J.A., Rojas, G. and Cerdas, L. (1985) Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom. Toxicon, 23, 887–893.
    • (1985) Toxicon , vol.23 , pp. 887-893
    • Gutierrez, J.M.1    Gene, J.A.2    Rojas, G.3    Cerdas, L.4
  • 14
    • 55949105234 scopus 로고    scopus 로고
    • Snake venomics of the Lesser Antillean pit vipers Bothrops caribbaeus and Bothrops lanceolatus: correlation with toxicological activities and immunoreactivity of a heterologous antivenom
    • Gutierrez, J.M., Sanz, L., Escolano, J., Fernandez, J., Lomonte, B., Angulo, Y., Rucavado, A. et al. (2008) Snake venomics of the Lesser Antillean pit vipers Bothrops caribbaeus and Bothrops lanceolatus: correlation with toxicological activities and immunoreactivity of a heterologous antivenom. J. Proteome Res. 7, 4396–4408.
    • (2008) J. Proteome Res. , vol.7 , pp. 4396-4408
    • Gutierrez, J.M.1    Sanz, L.2    Escolano, J.3    Fernandez, J.4    Lomonte, B.5    Angulo, Y.6    Rucavado, A.7
  • 15
    • 73649132296 scopus 로고    scopus 로고
    • Impact of regional variation in Bothrops asper snake venom on the design of antivenoms: integrating antivenomics and neutralization approaches
    • Gutierrez, J.M., Sanz, L., Flores-Diaz, M., Figueroa, L., Madrigal, M., Herrera, M., Villalta, M. et al. (2010) Impact of regional variation in Bothrops asper snake venom on the design of antivenoms: integrating antivenomics and neutralization approaches. J. Proteome Res. 9, 564–577.
    • (2010) J. Proteome Res. , vol.9 , pp. 564-577
    • Gutierrez, J.M.1    Sanz, L.2    Flores-Diaz, M.3    Figueroa, L.4    Madrigal, M.5    Herrera, M.6    Villalta, M.7
  • 16
    • 79957509785 scopus 로고    scopus 로고
    • Antivenoms for the treatment of snakebite envenomings: the road ahead
    • Gutierrez, J.M., Leon, G. and Burnouf, T. (2011) Antivenoms for the treatment of snakebite envenomings: the road ahead. Biologicals, 39, 129–142.
    • (2011) Biologicals , vol.39 , pp. 129-142
    • Gutierrez, J.M.1    Leon, G.2    Burnouf, T.3
  • 18
    • 84874985385 scopus 로고    scopus 로고
    • A coat-independent superinfection exclusion rapidly imposed in Nicotiana benthamiana cells by tobacco mosaic virus is not prevented by depletion of the movement protein
    • Julve, J.M., Gandia, A., Fernandez-Del-Carmen, A., Sarrion-Perdigones, A., Castelijns, B., Granell, A. and Orzaez, D. (2013) A coat-independent superinfection exclusion rapidly imposed in Nicotiana benthamiana cells by tobacco mosaic virus is not prevented by depletion of the movement protein. Plant Mol. Biol. 81, 553–564.
    • (2013) Plant Mol. Biol. , vol.81 , pp. 553-564
    • Julve, J.M.1    Gandia, A.2    Fernandez-Del-Carmen, A.3    Sarrion-Perdigones, A.4    Castelijns, B.5    Granell, A.6    Orzaez, D.7
  • 19
    • 84990227021 scopus 로고    scopus 로고
    • Snakebites: costing recombinant antivenoms
    • Laustsen, A.H. (2016) Snakebites: costing recombinant antivenoms. Nature, 538, 41.
    • (2016) Nature , vol.538 , pp. 41
    • Laustsen, A.H.1
  • 21
    • 84866676037 scopus 로고    scopus 로고
    • Antivenoms for snakebite: design, function, and controversies
    • Lavonas, E.J. (2012) Antivenoms for snakebite: design, function, and controversies. Curr. Pharm. Biotechnol. 13, 1980–1986.
    • (2012) Curr. Pharm. Biotechnol. , vol.13 , pp. 1980-1986
    • Lavonas, E.J.1
  • 22
    • 2342525801 scopus 로고    scopus 로고
    • In planta engineering of viral RNA replicons: Efficient assembly by recombination of DNA modules delivered by Agrobacterium
    • Marillonnet, S., Giritch, A., Gils, M., Kandzia, R., Klimyuk, V. and Gleba, Y. (2004) In planta engineering of viral RNA replicons: Efficient assembly by recombination of DNA modules delivered by Agrobacterium. Proc. Natl. Acad. Sci. USA, 101, 6852–6857.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 6852-6857
    • Marillonnet, S.1    Giritch, A.2    Gils, M.3    Kandzia, R.4    Klimyuk, V.5    Gleba, Y.6
  • 23
    • 24944498904 scopus 로고    scopus 로고
    • Systemic Agrobacterium tumefaciens-mediated transfection of viral replicons for efficient transient expression in plants
    • Marillonnet, S., Thoeringer, C., Kandzia, R., Klimyuk, V. and Gleba, Y. (2005) Systemic Agrobacterium tumefaciens-mediated transfection of viral replicons for efficient transient expression in plants. Nat. Biotechnol. 23, 718–723.
    • (2005) Nat. Biotechnol. , vol.23 , pp. 718-723
    • Marillonnet, S.1    Thoeringer, C.2    Kandzia, R.3    Klimyuk, V.4    Gleba, Y.5
  • 24
    • 79953234180 scopus 로고    scopus 로고
    • Plant-made pharmaceuticals: leading products and production platforms
    • Paul, M. and Ma, J.K. (2011) Plant-made pharmaceuticals: leading products and production platforms. Biotechnol. Appl. Biochem. 58, 58–67.
    • (2011) Biotechnol. Appl. Biochem. , vol.58 , pp. 58-67
    • Paul, M.1    Ma, J.K.2
  • 25
    • 84942191097 scopus 로고    scopus 로고
    • Commercialization of new biotechnology: a systematic review of 16 commercial case studies in a novel manufacturing sector
    • Paul, M.J., Thangaraj, H. and Ma, J.K. (2015) Commercialization of new biotechnology: a systematic review of 16 commercial case studies in a novel manufacturing sector. Plant Biotechnol. J. 13, 1209–1220.
    • (2015) Plant Biotechnol. J. , vol.13 , pp. 1209-1220
    • Paul, M.J.1    Thangaraj, H.2    Ma, J.K.3
  • 26
    • 84863778657 scopus 로고    scopus 로고
    • Second generation snake antivenomics: comparing immunoaffinity and immunodepletion protocols
    • Pla, D., Gutierrez, J.M. and Calvete, J.J. (2012) Second generation snake antivenomics: comparing immunoaffinity and immunodepletion protocols. Toxicon, 60, 688–699.
    • (2012) Toxicon , vol.60 , pp. 688-699
    • Pla, D.1    Gutierrez, J.M.2    Calvete, J.J.3
  • 28
    • 84962710108 scopus 로고    scopus 로고
    • A heterologous multiepitope DNA prime/recombinant protein boost immunisation strategy for the development of an antiserum against micrurus corallinus (Coral Snake) venom
    • Ramos, H.R., Junqueira-de-Azevedo Ide, L., Novo, J.B., Castro, K., Duarte, C.G., Machado-de-Avila, R.A., Chavez-Olortegui, C. et al. (2016) A heterologous multiepitope DNA prime/recombinant protein boost immunisation strategy for the development of an antiserum against micrurus corallinus (Coral Snake) venom. PLoS Negl. Trop Dis. 10, e0004484.
    • (2016) PLoS Negl. Trop Dis. , vol.10
    • Ramos, H.R.1    Junqueira-de-Azevedo Ide, L.2    Novo, J.B.3    Castro, K.4    Duarte, C.G.5    Machado-de-Avila, R.A.6    Chavez-Olortegui, C.7
  • 31
    • 77956060887 scopus 로고    scopus 로고
    • Preclinical assessment of the neutralizing capacity of antivenoms produced in six Latin American countries against medically-relevant Bothrops snake venoms
    • Segura, A., Castillo, M.C., Nunez, V., Yarleque, A., Goncalves, L.R., Villalta, M., Bonilla, C. et al. (2010) Preclinical assessment of the neutralizing capacity of antivenoms produced in six Latin American countries against medically-relevant Bothrops snake venoms. Toxicon, 56, 980–989.
    • (2010) Toxicon , vol.56 , pp. 980-989
    • Segura, A.1    Castillo, M.C.2    Nunez, V.3    Yarleque, A.4    Goncalves, L.R.5    Villalta, M.6    Bonilla, C.7
  • 32
    • 0006157257 scopus 로고
    • Biochemical and immunological aspects of the exclusion of lambda by superinfection with T4
    • Soller, A. and Epstein, H.T. (1965) Biochemical and immunological aspects of the exclusion of lambda by superinfection with T4. Virology, 26, 715–726.
    • (1965) Virology , vol.26 , pp. 715-726
    • Soller, A.1    Epstein, H.T.2
  • 35
    • 84055209237 scopus 로고    scopus 로고
    • Facilitative and antagonistic interactions between plant viruses in mixed infections
    • Syller, J. (2012) Facilitative and antagonistic interactions between plant viruses in mixed infections. Mol. Plant Pathol. 13, 204–216.
    • (2012) Mol. Plant Pathol. , vol.13 , pp. 204-216
    • Syller, J.1
  • 36
    • 0021061641 scopus 로고
    • Development of simple standard assay procedures for the characterization of snake venom
    • Theakston, R.D. and Reid, H.A. (1983) Development of simple standard assay procedures for the characterization of snake venom. Bull. World Health Organ. 61, 949–956.
    • (1983) Bull. World Health Organ. , vol.61 , pp. 949-956
    • Theakston, R.D.1    Reid, H.A.2
  • 37
    • 84920959275 scopus 로고    scopus 로고
    • Techno-economic analysis of horseradish peroxidase production using a transient expression system in Nicotiana benthamiana
    • Walwyn, D.R., Huddy, S.M. and Rybicki, E.P. (2015) Techno-economic analysis of horseradish peroxidase production using a transient expression system in Nicotiana benthamiana. Appl. Biochem. Biotechnol. 175, 841–854.
    • (2015) Appl. Biochem. Biotechnol. , vol.175 , pp. 841-854
    • Walwyn, D.R.1    Huddy, S.M.2    Rybicki, E.P.3
  • 38
    • 4744363468 scopus 로고    scopus 로고
    • A novel P-I class metalloproteinase with broad substrate-cleaving activity, agkislysin, from Agkistrodon acutus venom
    • Wang, W.J., Shih, C.H. and Huang, T.F. (2004) A novel P-I class metalloproteinase with broad substrate-cleaving activity, agkislysin, from Agkistrodon acutus venom. Biochem. Biophys. Res. Commun. 324, 224–230.
    • (2004) Biochem. Biophys. Res. Commun. , vol.324 , pp. 224-230
    • Wang, W.J.1    Shih, C.H.2    Huang, T.F.3
  • 39
    • 0141877349 scopus 로고    scopus 로고
    • Wilensky, U. (1999) NetLogo. http://ccl.northwestern.edu/netlogo/.
    • (1999) NetLogo
    • Wilensky, U.1
  • 41
    • 81555234540 scopus 로고    scopus 로고
    • iAssembler: a package for de novo assembly of Roche-454/Sanger transcriptome sequences
    • Zheng, Y., Zhao, L., Gao, J. and Fei, Z. (2011) iAssembler: a package for de novo assembly of Roche-454/Sanger transcriptome sequences. BMC Bioinform. 12, 453.
    • (2011) BMC Bioinform. , vol.12 , pp. 453
    • Zheng, Y.1    Zhao, L.2    Gao, J.3    Fei, Z.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.