Dietary alterations modulate susceptibility to Plasmodium infection

Nature Microbiology

Volumn 2, Issue 12, 2017, Pages 1600-1607

  Zuzarte Luís, Vanessa ^a   Mello Vieira, João ^a   Marreiros, Inês M ^a   Liehl, Peter ^a   Chora, Ângelo F ^a   Carret, Céline K ^a,b   Carvalho, Tânia ^a   Mota, Maria M ^a  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b EMBO   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ETOMOXIR; REACTIVE OXYGEN METABOLITE; ANTIOXIDANT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; FATTY ACID OXIDATION; GENETIC ANALYSIS; HEPATITIS; INFECTION CONTROL; LIPID DIET; LIVER CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARASITE LOAD; PARASITOSIS; PLASMODIUM; PLASMODIUM INFECTION; PRIORITY JOURNAL; SPOROZOITE; SURVIVAL; TRANSCRIPTION REGULATION; VIRUS REPLICATION; ANIMAL; BLOOD; C57BL MOUSE; DIET THERAPY; DISEASE MODEL; FEMALE; GENE EXPRESSION PROFILING; GENETICS; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; GLUCOSE TOLERANCE TEST; HEP-G2 CELL LINE; HOST PARASITE INTERACTION; HUMAN; LIVER; LIVER DISEASE; MACROPHAGE; MALARIA; MALE; METABOLISM; PARASITOLOGY; PATHOLOGY; PLASMODIUM BERGHEI; PROCEDURES; SICKLE CELL TRAIT;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; GLUCOSE TOLERANCE TEST; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; HEP G2 CELLS; HEPATOCYTES; HOST-PARASITE INTERACTIONS; HUMANS; LIVER; LIVER DISEASES; MACROPHAGES; MALARIA; MALE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PARASITE LOAD; PLASMODIUM BERGHEI; REACTIVE OXYGEN SPECIES; SICKLE CELL TRAIT; SPOROZOITES;

EID: 85029821671     PISSN: None     EISSN: 20585276     Source Type: Journal    
DOI: 10.1038/s41564-017-0025-2     Document Type: Article

References (36)

1. Karlsson, E. K., Kwiatkowski, D. P. & Sabeti, P. C. Natural selection and infectious disease in human populations. Nat. Rev. Genet. 15, 379-393 (2014).
2. Traoré, K., Arama, C., Médebielle, M., Doumbo, O. & Picot, S. Do advanced glycation end-products play a role in malaria susceptibility? Parasite 23, 15 (2016).
3. Wymann, M. P. & Schneiter, R. Lipid signalling in disease. Nat. Rev. Mol. Cell Biol. 9, 162-176 (2008).
4. Medzhitov, R. Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1, 135-145 (2001).
5. Matsuzawa-Nagata, N. et al. Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity. Metabolism 57, 1071-1077 (2008).
6. Wenk, M. R. Lipidomics of host-pathogen interactions. FEBS Lett. 580, 5541-5551 (2006).
7. Prudêncio, M., Rodriguez, A. & Mota, M. M. The silent path to thousands of merozoites: the Plasmodium liver stage. Nat. Rev. Microbiol. 4, 849-856 (2006).
8. Deschermeier, C. et al. Mitochondrial lipoic acid scavenging is essential for Plasmodium berghei liver stage development. Cell. Microbiol. 14, 416-430 (2012).
9. Itoe, M. A. et al. Host cell phosphatidylcholine is a key mediator of malaria parasite survival during liver stage infection. Cell Host Microbe 16, 778-786 (2014).
10. Wiedemann, M. S. et al. Short-term HFD does not alter lipolytic function of adipocytes. Adipocyte 3, 115-120 (2014).
11. Sinnis, P., Willnow, T. E., Briones, M. R. S. & Herzfl, J. Remnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes. J. Exp. Med. 184, 945-954 (1996).
12. Liehl, P. & Mota, M. M. Innate recognition of malarial parasites by mammalian hosts. Int. J. Parasitol. 42, 557-566 (2012).
13. Mota, M. M. & Rodriguez, A. (eds) Malaria: Immune Response to Infection and Vaccination (Springer, Cham, 2017).
14. Lyons, C. L., Kennedy, E. B. & Roche, H. M. Metabolic inflammationdifferential modulation by dietary constituents. Nutrients 8, E247 (2016).
15. Deng, Z. et al. Immature myeloid cells induced by a high-fat diet contribute to liver inflammation. Hepatology 50, 1412-1420 (2009).
16. Fritsche, K. L. The science of fatty acids and inflammation. Adv. Nutr. 6, 293S-301S (2015).
17. Hanson, K. K. et al. Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins. Proc. Natl. Acad. Sci. USA 110, E2838-E2847 (2013).
18. Raj, L. et al. Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature 475, 231-234 (2011).
19. Cardoso, A. R., Kakimoto, P. A. H. B. & Kowaltowski, A. J. Diet-sensitive sources of reactive oxygen species in liver mitochondria: role of very long chain acyl-CoA dehydrogenases. PLoS ONE http://doi.org/10.1371/journal. pone.0077088 (2013).
20. Luiken, J. J. F. P. et al. Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition in vivo does not alter cardiac long-chain fatty acid uptake and oxidation rates. Biochem. J. 419, 447-455 (2009).
21. Kwiatkowski, D. P. P. How malaria has affected the human genome and what human genetics can teach us about malaria. Am. J. Hum. Genet. 77, 171-190 (2005).
22. Mejia, P. et al. Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression. Nat. Commun. 6, 6050 (2015).
23. Mancio-Silva, L. et al. Nutrient sensing modulates malaria parasite virulence. Nature 547, 213-216 (2017).
24. Miller, J. L., Harupa, A., Kappe, S. H. I. & Mikolajczak, S. A. Plasmodium yoelii macrophage migration inhibitory factor is necessary for efficient liver-stage development. Infect. Immun. 80, 1399-1407 (2012).
25. Ng, S. et al. Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro. Dis. Model. Mech. 7, 215-224 (2014).
26. Cappellini, M. & Fiorelli, G. Glucose-6-phosphate dehydrogenase deficiency. Lancet 371, 64-74 (2008).
27. Voskou, S., Aslan, M., Fanis, P., Phylactides, M. & Kleanthous, M. Oxidative stress in beta-thalassaemia and sickle cell disease. Redox Biol. 6, 226-239 (2015).
28. NCD Risk Factor Collaboration (NCD-RisC). et al. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants. Lancet 387, 1377-1396 (2016).
29. Arama, C. et al. Ethnic differences in susceptibility to malaria: what have we learned from immuno-epidemiological studies in West Africa? Acta Tropica 146, 152-156 (2015).
30. Glew, R. H. et al. Lipid profiles and trans fatty acids in serum phospholipids of semi-nomadic fulani in Northern Nigeria. J. Heal. Popul. Nutr. 28, 159-166 (2010).
31. Zuzarte-Luis, V., Sales-Dias, J. & Mota, M. M. Simple, sensitive and quantitative bioluminescence assay for determination of malaria pre-patent period. Malar. J. 13, 15 (2014).
32. Thoolen, B. et al. Proliferative and nonproliferative lesions of the rat and mouse hepatobiliary system. Toxicol. Pathol. 38, 5S-81S (2010).
33. van Goor, H., Gerrits, P. O. & Grond, J. The application of lipid-soluble stains in plastic-embedded sections. Histochemistry 85, 251-253 (1986).
34. Umemura, A. et al. Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. Cell Metab. 20, 133-144 (2014).
35. Zhang, W. et al. PCB 126 and other dioxin-like PCBs specifically suppress hepatic PEPCK expression via the aryl hydrocarbon receptor. PLoS ONE 7, e37103 (2012).
36. Gonçalves, L. A., Vigário, A. M. & Penha-Gonçalves, C. Improved isolation of murine hepatocytes for in vitro malaria liver stage studies. Malar. J. 6, 169 (2007).